JP2001518509A - グルココルチコイド関連機能不全に関連した精神病の処置のための方法。 - Google Patents
グルココルチコイド関連機能不全に関連した精神病の処置のための方法。Info
- Publication number
- JP2001518509A JP2001518509A JP2000514650A JP2000514650A JP2001518509A JP 2001518509 A JP2001518509 A JP 2001518509A JP 2000514650 A JP2000514650 A JP 2000514650A JP 2000514650 A JP2000514650 A JP 2000514650A JP 2001518509 A JP2001518509 A JP 2001518509A
- Authority
- JP
- Japan
- Prior art keywords
- psychosis
- glucocorticoid receptor
- receptor antagonist
- psychotic
- mifepristone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
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- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
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Landscapes
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| PCT/US1998/020906 WO1999017779A1 (en) | 1997-10-06 | 1998-10-05 | Methods for treating psychosis associated with glucocorticoid related dysfunction |
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| JP2008271442A Division JP2009051858A (ja) | 1997-10-06 | 2008-10-21 | グルココルチコイド関連機能不全に関連した精神病の処置のための方法。 |
| JP2009071039A Division JP5180125B2 (ja) | 1997-10-06 | 2009-03-23 | グルココルチコイド関連機能不全に関連した精神病の処置のための方法。 |
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| JP2008271442A Withdrawn JP2009051858A (ja) | 1997-10-06 | 2008-10-21 | グルココルチコイド関連機能不全に関連した精神病の処置のための方法。 |
| JP2009071039A Expired - Fee Related JP5180125B2 (ja) | 1997-10-06 | 2009-03-23 | グルココルチコイド関連機能不全に関連した精神病の処置のための方法。 |
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| JP2009071039A Expired - Fee Related JP5180125B2 (ja) | 1997-10-06 | 2009-03-23 | グルココルチコイド関連機能不全に関連した精神病の処置のための方法。 |
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| EP (1) | EP1023074B1 (https=) |
| JP (3) | JP2001518509A (https=) |
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| CN (3) | CN1528315A (https=) |
| AT (1) | ATE332696T1 (https=) |
| AU (1) | AU747956B2 (https=) |
| CA (1) | CA2302586C (https=) |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2005513024A (ja) * | 2001-11-23 | 2005-05-12 | アクゾ・ノベル・エヌ・ベー | グルココルチコイド受容体アンタゴニストを用いる大うつ病性障害の治療 |
| JP2005521637A (ja) * | 2001-10-26 | 2005-07-21 | アクゾ・ノベル・エヌ・ベー | 大うつ病性障害の治療における（１１β，１７β）−１１−（１，３−ベンゾジオキソール−５−イル）−１７−ヒドロキシ−１７−（１−プロピニル）エストラ−４，９−ジエン−３−オンの使用 |
| JP2005526843A (ja) * | 2002-04-29 | 2005-09-08 | コーセプト セラピューティクス， インコーポレイテッド | 電気痙攣療法（「ｅｃｔ」）に対する治療応答を増大させるための方法 |
| JP2015007128A (ja) * | 2007-06-15 | 2015-01-15 | リサーチ トライアングル インスティテュート | Ｇａｂａレセプタークロライドイオノフォアの潜在的アロステリック調節特性を有するアンドロスタンステロイドおよびプレグナンステロイド |
| JP2018507226A (ja) * | 2015-03-02 | 2018-03-15 | コーセプト セラピューティクス， インコーポレイテッド | Ａｃｔｈ分泌腫瘍を処置するための糖質コルチコイドレセプターアンタゴニストおよびソマトスタチンアナログの使用 |
| JP2018127492A (ja) * | 2011-02-03 | 2018-08-16 | ポップ テスト オンコロジー エルエルシー | 診断と治療のためのシステムおよび方法 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| EP0903146A1 (en) * | 1997-09-23 | 1999-03-24 | Applied Research Systems ARS Holdings N.V. | 21-Hydroy-6,19-oxidoprogesterone (210h-60p) as antiglucocorticoid |
| GB9915625D0 (en) * | 1999-07-02 | 1999-09-01 | Cortendo Ab | Method |
| US6620802B1 (en) * | 1999-11-23 | 2003-09-16 | Corcept Therapeutics, Inc. | Methods of treating mild cognitive impairment using a glucocorticoid-specific receptor antagonist |
| SI1325022T1 (sl) * | 2000-09-18 | 2007-04-30 | Applied Research Systems | Metoda za pripravo 21-hidroksi-6,19-oksidoprogesterona (21oh-6op) |
| CN1820756A (zh) * | 2001-03-23 | 2006-08-23 | 科塞普特治疗公司 | 使用糖皮质激素受体特效拮抗剂治疗压力症的方法 |
| US7163934B2 (en) | 2001-05-04 | 2007-01-16 | Corcept Therapeutics, Inc. | Methods for treating delirium glucocorticoid receptor-specific antagonists |
| DE60238671D1 (de) * | 2001-05-04 | 2011-02-03 | Corcept Therapeutics Inc | Verwendung von glucocorticoid-rezeptor-spezifischen antagonisten zur behandlung von delirium |
| AU2002319665B2 (en) | 2001-07-23 | 2006-09-21 | Corcept Therapeutics, Inc. | Methods for preventing antipsychotic-induced weight gain |
| IL160649A0 (en) * | 2001-08-31 | 2004-07-25 | Corcept Therapeutics Inc | Methods for inhibiting cognitive deterioration in adults with down syndrome |
| CN1665515A (zh) * | 2002-07-02 | 2005-09-07 | 科塞普特治疗公司 | 治疗与干扰素α治疗相关的精神病的方法 |
| WO2004054587A1 (en) * | 2002-12-18 | 2004-07-01 | University Of Zurich | Treatment of neuro-psychiatric disorders |
| EP1599208A4 (en) * | 2003-02-04 | 2007-09-12 | Corcept Therapeutics Inc | ANTIGLUCOCORTICOIDES FOR THE TREATMENT OF POSTPARTAL PSYCHOSIS |
| US8097606B2 (en) * | 2003-07-23 | 2012-01-17 | Corcept Therapeutics, Inc. | Antiglucocorticoids for the treatment of catatonia |
| GB0400031D0 (en) | 2004-01-03 | 2004-02-04 | Univ Sheffield | Depression treatment |
| US20090156565A1 (en) * | 2004-12-03 | 2009-06-18 | The Children's Hospital Of Philadelphia | Composition and use thereof in enhancing a therapeutic effect of an antiepileptic drug |
| CN100588393C (zh) * | 2004-12-15 | 2010-02-10 | 上海三合生物技术有限公司 | 赛米司酮类用于治疗抑郁症的用途 |
| US20060229505A1 (en) * | 2005-04-08 | 2006-10-12 | Mundt James C | Method and system for facilitating respondent identification with experiential scaling anchors to improve self-evaluation of clinical treatment efficacy |
| JP2009535430A (ja) * | 2006-05-02 | 2009-10-01 | コーセプト セラピューティクス， インコーポレイテッド | Ｉｌ−２を摂取している患者における抑うつを処置するためのグルココルチコイドレセプターｉｉアンタゴニストの使用 |
| EP1987814A1 (en) * | 2007-04-30 | 2008-11-05 | Exelgyn | Mifepristone pharmaceutical compositions and their methods of preparation |
| RU2327448C1 (ru) | 2007-05-23 | 2008-06-27 | Виктор Иванович Рощин | Средство для лечения зависимости от этилового спирта и/или от наркотиков, фармацевтическая композиция, активный ингредиент фармацевтической композиции, способ лечения зависимости от этилового спирта и/или от наркотиков для лечения психосоматических и неврологических осложнений у алкоголиков и/или наркоманов |
| EP2576582B1 (en) * | 2010-05-26 | 2019-09-18 | Corcept Therapeutics, Inc. | Treatment of muscular dystrophy |
| US10500216B2 (en) | 2011-11-18 | 2019-12-10 | Corcept Therapeutics, Inc. | Optimizing mifepristone absorption |
| US8986677B2 (en) * | 2012-07-30 | 2015-03-24 | Pop Test Cortisol Llc | Therapeutic compositions and methods |
| US9943526B2 (en) | 2015-04-21 | 2018-04-17 | Corcept Therapeutics, Inc. | Optimizing mifepristone levels for cushing's patients |
| PH12017502099B1 (en) * | 2015-05-18 | 2023-08-30 | Corcept Therapeutics Inc | Methods for diagnosing and assessing treatment for cushing's syndrome |
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| AU2020239920A1 (en) | 2019-03-18 | 2021-11-04 | Arnold L. Newman | Method of improving insulin sensitivity |
| PH12022551430A1 (en) | 2019-12-11 | 2023-11-20 | Corcept Therapeutics Inc | Methods of treating antipsychotic-induced weight gain with miricorilant |
| WO2023033900A1 (en) | 2021-09-06 | 2023-03-09 | Slayback Pharma Llc | Pharmaceutical compositions of mifepristone |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4814333A (en) * | 1987-07-28 | 1989-03-21 | The Trustees Of Dartmouth College | Method for treatment of hypercortisolemic, depressed patients |
| US5348729A (en) * | 1988-11-30 | 1994-09-20 | The United States Of America As Represented By The Department Of Health And Human Services | Evaluative means for detecting inflammatory reactivity |
| FR2696934B1 (fr) * | 1992-10-20 | 1995-06-02 | Conservatoire Nal Arts Metiers | Dérivés de stéroïdes naturels 3B hydroxyles ayant des propriétés de déclenchement et de stimulation de l'immunité, composition les contenant et procédé pour les obtenir. |
| IL118974A (en) * | 1995-08-17 | 2001-09-13 | Akzo Nobel Nv | History 11 - (Transformed Phenyl) - Astra - 4, 9 - Diane, their preparation and pharmaceutical preparations containing them |
| FR2739029B1 (fr) * | 1995-09-21 | 1997-11-21 | Roussel Uclaf | Nouvelle application therapeutique des composes antimineralo-corticoides |
| DE69737791D1 (de) * | 1996-04-09 | 2007-07-19 | Univ Edinburgh | Verwendung von 7-alpha-substituierten steroiden zur behandlung von neuropsychiatrischen erkrankungen |
| FR2757400B1 (fr) * | 1996-12-19 | 1999-12-17 | Hoechst Marion Roussel Inc | Application des composes antiglucocorticoides dans le traitement des psychoses ou des comportements addictifs |
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- 1998-10-05 CN CNA2006101003657A patent/CN1919199A/zh active Pending
- 1998-10-05 KR KR1020077003769A patent/KR100840957B1/ko not_active Expired - Fee Related
- 1998-10-05 CN CNB988097923A patent/CN1187053C/zh not_active Expired - Fee Related
- 1998-10-05 CA CA002302586A patent/CA2302586C/en not_active Expired - Fee Related
- 1998-10-05 KR KR1020007003683A patent/KR100804558B1/ko not_active Expired - Fee Related
- 1998-10-05 JP JP2000514650A patent/JP2001518509A/ja not_active Withdrawn
- 1998-10-05 DE DE69835225T patent/DE69835225T2/de not_active Expired - Lifetime
- 1998-10-05 NZ NZ503250A patent/NZ503250A/en not_active IP Right Cessation
- 1998-10-05 PT PT98950911T patent/PT1023074E/pt unknown
-
1999
- 1999-02-04 US US09/244,457 patent/US6150349A/en not_active Expired - Lifetime
-
2000
- 2000-04-04 IL IL135469A patent/IL135469A/en not_active IP Right Cessation
- 2000-04-05 NO NO20001744A patent/NO327233B1/no not_active IP Right Cessation
- 2000-08-15 US US09/639,377 patent/US6362173B1/en not_active Expired - Lifetime
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2006
- 2006-10-05 CY CY20061101439T patent/CY1106330T1/el unknown
-
2008
- 2008-10-21 JP JP2008271442A patent/JP2009051858A/ja not_active Withdrawn
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2009
- 2009-03-23 JP JP2009071039A patent/JP5180125B2/ja not_active Expired - Fee Related
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005521637A (ja) * | 2001-10-26 | 2005-07-21 | アクゾ・ノベル・エヌ・ベー | 大うつ病性障害の治療における（１１β，１７β）−１１−（１，３−ベンゾジオキソール−５−イル）−１７−ヒドロキシ−１７−（１−プロピニル）エストラ−４，９−ジエン−３−オンの使用 |
| JP2005513024A (ja) * | 2001-11-23 | 2005-05-12 | アクゾ・ノベル・エヌ・ベー | グルココルチコイド受容体アンタゴニストを用いる大うつ病性障害の治療 |
| JP2005526843A (ja) * | 2002-04-29 | 2005-09-08 | コーセプト セラピューティクス， インコーポレイテッド | 電気痙攣療法（「ｅｃｔ」）に対する治療応答を増大させるための方法 |
| JP2011116771A (ja) * | 2002-04-29 | 2011-06-16 | Corcept Therapeutics Inc | 電気痙攣療法（「ｅｃｔ」）に対する治療応答を増大させるための方法 |
| JP2015007128A (ja) * | 2007-06-15 | 2015-01-15 | リサーチ トライアングル インスティテュート | Ｇａｂａレセプタークロライドイオノフォアの潜在的アロステリック調節特性を有するアンドロスタンステロイドおよびプレグナンステロイド |
| JP2018127492A (ja) * | 2011-02-03 | 2018-08-16 | ポップ テスト オンコロジー エルエルシー | 診断と治療のためのシステムおよび方法 |
| JP2018507226A (ja) * | 2015-03-02 | 2018-03-15 | コーセプト セラピューティクス， インコーポレイテッド | Ａｃｔｈ分泌腫瘍を処置するための糖質コルチコイドレセプターアンタゴニストおよびソマトスタチンアナログの使用 |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1528315A (zh) | 2004-09-15 |
| NZ503250A (en) | 2001-09-28 |
| PT1023074E (pt) | 2006-12-29 |
| JP2009051858A (ja) | 2009-03-12 |
| CN1187053C (zh) | 2005-02-02 |
| WO1999017779A1 (en) | 1999-04-15 |
| NO20001744L (no) | 2000-04-05 |
| DE69835225D1 (de) | 2006-08-24 |
| KR20010024431A (ko) | 2001-03-26 |
| CA2302586A1 (en) | 1999-04-15 |
| AU747956B2 (en) | 2002-05-30 |
| JP5180125B2 (ja) | 2013-04-10 |
| NO327233B1 (no) | 2009-05-18 |
| EP1023074A1 (en) | 2000-08-02 |
| EP1023074B1 (en) | 2006-07-12 |
| CN1919199A (zh) | 2007-02-28 |
| KR100840957B1 (ko) | 2008-06-24 |
| IL135469A (en) | 2007-03-08 |
| CY1106330T1 (el) | 2011-10-12 |
| US6150349A (en) | 2000-11-21 |
| IL135469A0 (en) | 2001-05-20 |
| ATE332696T1 (de) | 2006-08-15 |
| KR100804558B1 (ko) | 2008-02-20 |
| CN1272788A (zh) | 2000-11-08 |
| US6362173B1 (en) | 2002-03-26 |
| DK1023074T3 (da) | 2006-11-06 |
| CA2302586C (en) | 2008-06-10 |
| DE69835225T2 (de) | 2007-07-05 |
| JP2009132743A (ja) | 2009-06-18 |
| KR20070032822A (ko) | 2007-03-22 |
| ES2268792T3 (es) | 2007-03-16 |
| AU9683298A (en) | 1999-04-27 |
| NO20001744D0 (no) | 2000-04-05 |
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