JP2001518509A - グルココルチコイド関連機能不全に関連した精神病の処置のための方法。 - Google Patents
グルココルチコイド関連機能不全に関連した精神病の処置のための方法。Info
- Publication number
- JP2001518509A JP2001518509A JP2000514650A JP2000514650A JP2001518509A JP 2001518509 A JP2001518509 A JP 2001518509A JP 2000514650 A JP2000514650 A JP 2000514650A JP 2000514650 A JP2000514650 A JP 2000514650A JP 2001518509 A JP2001518509 A JP 2001518509A
- Authority
- JP
- Japan
- Prior art keywords
- psychosis
- glucocorticoid receptor
- receptor antagonist
- psychotic
- mifepristone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
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- A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
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- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
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- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
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Landscapes
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| PCT/US1998/020906 WO1999017779A1 (en) | 1997-10-06 | 1998-10-05 | Methods for treating psychosis associated with glucocorticoid related dysfunction |
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| JP2008271442A Division JP2009051858A (ja) | 1997-10-06 | 2008-10-21 | グルココルチコイド関連機能不全に関連した精神病の処置のための方法。 |
| JP2009071039A Division JP5180125B2 (ja) | 1997-10-06 | 2009-03-23 | グルココルチコイド関連機能不全に関連した精神病の処置のための方法。 |
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| JP2008271442A Withdrawn JP2009051858A (ja) | 1997-10-06 | 2008-10-21 | グルココルチコイド関連機能不全に関連した精神病の処置のための方法。 |
| JP2009071039A Expired - Fee Related JP5180125B2 (ja) | 1997-10-06 | 2009-03-23 | グルココルチコイド関連機能不全に関連した精神病の処置のための方法。 |
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| JP2008271442A Withdrawn JP2009051858A (ja) | 1997-10-06 | 2008-10-21 | グルココルチコイド関連機能不全に関連した精神病の処置のための方法。 |
| JP2009071039A Expired - Fee Related JP5180125B2 (ja) | 1997-10-06 | 2009-03-23 | グルココルチコイド関連機能不全に関連した精神病の処置のための方法。 |
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| EP (1) | EP1023074B1 (https=) |
| JP (3) | JP2001518509A (https=) |
| KR (2) | KR100840957B1 (https=) |
| CN (3) | CN1528315A (https=) |
| AT (1) | ATE332696T1 (https=) |
| AU (1) | AU747956B2 (https=) |
| CA (1) | CA2302586C (https=) |
| CY (1) | CY1106330T1 (https=) |
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| NZ (1) | NZ503250A (https=) |
| PT (1) | PT1023074E (https=) |
| WO (1) | WO1999017779A1 (https=) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2005513024A (ja) * | 2001-11-23 | 2005-05-12 | アクゾ・ノベル・エヌ・ベー | グルココルチコイド受容体アンタゴニストを用いる大うつ病性障害の治療 |
| JP2005521637A (ja) * | 2001-10-26 | 2005-07-21 | アクゾ・ノベル・エヌ・ベー | 大うつ病性障害の治療における(11β,17β)−11−(1,3−ベンゾジオキソール−5−イル)−17−ヒドロキシ−17−(1−プロピニル)エストラ−4,9−ジエン−3−オンの使用 |
| JP2005526843A (ja) * | 2002-04-29 | 2005-09-08 | コーセプト セラピューティクス, インコーポレイテッド | 電気痙攣療法(「ect」)に対する治療応答を増大させるための方法 |
| JP2015007128A (ja) * | 2007-06-15 | 2015-01-15 | リサーチ トライアングル インスティテュート | Gabaレセプタークロライドイオノフォアの潜在的アロステリック調節特性を有するアンドロスタンステロイドおよびプレグナンステロイド |
| JP2018507226A (ja) * | 2015-03-02 | 2018-03-15 | コーセプト セラピューティクス, インコーポレイテッド | Acth分泌腫瘍を処置するための糖質コルチコイドレセプターアンタゴニストおよびソマトスタチンアナログの使用 |
| JP2018127492A (ja) * | 2011-02-03 | 2018-08-16 | ポップ テスト オンコロジー エルエルシー | 診断と治療のためのシステムおよび方法 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| EP0903146A1 (en) * | 1997-09-23 | 1999-03-24 | Applied Research Systems ARS Holdings N.V. | 21-Hydroy-6,19-oxidoprogesterone (210h-60p) as antiglucocorticoid |
| GB9915625D0 (en) * | 1999-07-02 | 1999-09-01 | Cortendo Ab | Method |
| US6620802B1 (en) | 1999-11-23 | 2003-09-16 | Corcept Therapeutics, Inc. | Methods of treating mild cognitive impairment using a glucocorticoid-specific receptor antagonist |
| US7071328B2 (en) * | 2000-09-18 | 2006-07-04 | Applied Research System Ars Holding N.V. | Method for the preparation of 21-hydroxy-6,19-oxidoprogesterone (21 oh-6op) |
| DE60232956D1 (de) | 2001-03-23 | 2009-08-27 | Corcept Therapeutics Inc | Verfahren zur behandlung von stressbedingten erkrankungen unter verwendung von glucocorticoid-rezepto-spezifischen antagonisten |
| WO2002096433A1 (en) * | 2001-05-04 | 2002-12-05 | Corcept Therapeutics, Inc. | Methods for treating delirium using glucocorticoid receptor-specific antagonists |
| US7163934B2 (en) | 2001-05-04 | 2007-01-16 | Corcept Therapeutics, Inc. | Methods for treating delirium glucocorticoid receptor-specific antagonists |
| CA2454339C (en) | 2001-07-23 | 2012-01-10 | Corcept Therapeutics, Inc. | Methods for preventing antipsychotic-induced weight gain |
| NZ531477A (en) * | 2001-08-31 | 2006-10-27 | Corcept Therapeutics Inc | Use of a glucocorticoid receptor antagonist comprising a steroidal skeleton with at least one phenyl-containing moiety in the 11-beta position of the steroidal skeleton to decrease cognitive deterioration in adults with Down's syndrome |
| JP2005535664A (ja) * | 2002-07-02 | 2005-11-24 | コーセプト セラピューティクス, インコーポレイテッド | インターフェロン−α治療に関連した精神病を処置するための方法 |
| WO2004054587A1 (en) * | 2002-12-18 | 2004-07-01 | University Of Zurich | Treatment of neuro-psychiatric disorders |
| JP2006516651A (ja) * | 2003-02-04 | 2006-07-06 | コーセプト セラピューティクス, インコーポレイテッド | 産後精神病の処置のための抗糖質コルチコイド |
| US8097606B2 (en) * | 2003-07-23 | 2012-01-17 | Corcept Therapeutics, Inc. | Antiglucocorticoids for the treatment of catatonia |
| GB0400031D0 (en) | 2004-01-03 | 2004-02-04 | Univ Sheffield | Depression treatment |
| US20090156565A1 (en) * | 2004-12-03 | 2009-06-18 | The Children's Hospital Of Philadelphia | Composition and use thereof in enhancing a therapeutic effect of an antiepileptic drug |
| CN100588393C (zh) * | 2004-12-15 | 2010-02-10 | 上海三合生物技术有限公司 | 赛米司酮类用于治疗抑郁症的用途 |
| US20060229505A1 (en) * | 2005-04-08 | 2006-10-12 | Mundt James C | Method and system for facilitating respondent identification with experiential scaling anchors to improve self-evaluation of clinical treatment efficacy |
| WO2007131041A2 (en) * | 2006-05-02 | 2007-11-15 | Corcept Therapeutics, Inc. | The use of a glucocorticoid receptor ii antagonist to treat depression in patients taking il-2 |
| EP1987814A1 (en) * | 2007-04-30 | 2008-11-05 | Exelgyn | Mifepristone pharmaceutical compositions and their methods of preparation |
| RU2327448C1 (ru) | 2007-05-23 | 2008-06-27 | Виктор Иванович Рощин | Средство для лечения зависимости от этилового спирта и/или от наркотиков, фармацевтическая композиция, активный ингредиент фармацевтической композиции, способ лечения зависимости от этилового спирта и/или от наркотиков для лечения психосоматических и неврологических осложнений у алкоголиков и/или наркоманов |
| WO2011150209A1 (en) * | 2010-05-26 | 2011-12-01 | Corcept Therapeutics, Inc. | Treatment of muscular dystrophy |
| US10500216B2 (en) | 2011-11-18 | 2019-12-10 | Corcept Therapeutics, Inc. | Optimizing mifepristone absorption |
| US8986677B2 (en) * | 2012-07-30 | 2015-03-24 | Pop Test Cortisol Llc | Therapeutic compositions and methods |
| US9943526B2 (en) | 2015-04-21 | 2018-04-17 | Corcept Therapeutics, Inc. | Optimizing mifepristone levels for cushing's patients |
| KR20180008627A (ko) * | 2015-05-18 | 2018-01-24 | 코어셉트 쎄라퓨틱스, 잉크. | 쿠싱 증후군을 진단하고 이에 대한 치료를 평가하는 방법 |
| CN114680890A (zh) * | 2016-10-21 | 2022-07-01 | 西铁城时计株式会社 | 检测装置 |
| EP4653047A3 (en) | 2019-03-18 | 2026-02-18 | Nieman, Lynnette K. | Mifepristone for use in improving insulin sensitivity |
| JP7569492B2 (ja) | 2019-12-11 | 2024-10-18 | コーセプト セラピューティクス, インコーポレイテッド | 抗精神病薬誘発性体重増加のミリコリラントによる治療方法 |
| US11878025B2 (en) * | 2021-09-06 | 2024-01-23 | Slayback Pharma Llc | Pharmaceutical compositions of mifepristone |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4814333A (en) * | 1987-07-28 | 1989-03-21 | The Trustees Of Dartmouth College | Method for treatment of hypercortisolemic, depressed patients |
| US5348729A (en) * | 1988-11-30 | 1994-09-20 | The United States Of America As Represented By The Department Of Health And Human Services | Evaluative means for detecting inflammatory reactivity |
| FR2696934B1 (fr) * | 1992-10-20 | 1995-06-02 | Conservatoire Nal Arts Metiers | Dérivés de stéroïdes naturels 3B hydroxyles ayant des propriétés de déclenchement et de stimulation de l'immunité, composition les contenant et procédé pour les obtenir. |
| IL118974A (en) * | 1995-08-17 | 2001-09-13 | Akzo Nobel Nv | History 11 - (Transformed Phenyl) - Astra - 4, 9 - Diane, their preparation and pharmaceutical preparations containing them |
| FR2739029B1 (fr) * | 1995-09-21 | 1997-11-21 | Roussel Uclaf | Nouvelle application therapeutique des composes antimineralo-corticoides |
| EP0954317B1 (en) * | 1996-04-09 | 2007-06-06 | The University Of Edinburgh | Use of 7 apha-substituted steroids to treat neuropsychiatric disorders |
| FR2757400B1 (fr) * | 1996-12-19 | 1999-12-17 | Hoechst Marion Roussel Inc | Application des composes antiglucocorticoides dans le traitement des psychoses ou des comportements addictifs |
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- 1998-10-05 CA CA002302586A patent/CA2302586C/en not_active Expired - Fee Related
- 1998-10-05 PT PT98950911T patent/PT1023074E/pt unknown
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- 1998-10-05 JP JP2000514650A patent/JP2001518509A/ja not_active Withdrawn
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- 1998-10-05 DE DE69835225T patent/DE69835225T2/de not_active Expired - Lifetime
- 1998-10-05 KR KR1020077003769A patent/KR100840957B1/ko not_active Expired - Fee Related
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- 1998-10-05 DK DK98950911T patent/DK1023074T3/da active
- 1998-10-05 CN CNA2006101003657A patent/CN1919199A/zh active Pending
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1999
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- 2000-04-05 NO NO20001744A patent/NO327233B1/no not_active IP Right Cessation
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005521637A (ja) * | 2001-10-26 | 2005-07-21 | アクゾ・ノベル・エヌ・ベー | 大うつ病性障害の治療における(11β,17β)−11−(1,3−ベンゾジオキソール−5−イル)−17−ヒドロキシ−17−(1−プロピニル)エストラ−4,9−ジエン−3−オンの使用 |
| JP2005513024A (ja) * | 2001-11-23 | 2005-05-12 | アクゾ・ノベル・エヌ・ベー | グルココルチコイド受容体アンタゴニストを用いる大うつ病性障害の治療 |
| JP2005526843A (ja) * | 2002-04-29 | 2005-09-08 | コーセプト セラピューティクス, インコーポレイテッド | 電気痙攣療法(「ect」)に対する治療応答を増大させるための方法 |
| JP2011116771A (ja) * | 2002-04-29 | 2011-06-16 | Corcept Therapeutics Inc | 電気痙攣療法(「ect」)に対する治療応答を増大させるための方法 |
| JP2015007128A (ja) * | 2007-06-15 | 2015-01-15 | リサーチ トライアングル インスティテュート | Gabaレセプタークロライドイオノフォアの潜在的アロステリック調節特性を有するアンドロスタンステロイドおよびプレグナンステロイド |
| JP2018127492A (ja) * | 2011-02-03 | 2018-08-16 | ポップ テスト オンコロジー エルエルシー | 診断と治療のためのシステムおよび方法 |
| JP2018507226A (ja) * | 2015-03-02 | 2018-03-15 | コーセプト セラピューティクス, インコーポレイテッド | Acth分泌腫瘍を処置するための糖質コルチコイドレセプターアンタゴニストおよびソマトスタチンアナログの使用 |
Also Published As
| Publication number | Publication date |
|---|---|
| NO327233B1 (no) | 2009-05-18 |
| PT1023074E (pt) | 2006-12-29 |
| CA2302586C (en) | 2008-06-10 |
| DE69835225T2 (de) | 2007-07-05 |
| KR100840957B1 (ko) | 2008-06-24 |
| AU9683298A (en) | 1999-04-27 |
| KR100804558B1 (ko) | 2008-02-20 |
| JP5180125B2 (ja) | 2013-04-10 |
| US6362173B1 (en) | 2002-03-26 |
| CA2302586A1 (en) | 1999-04-15 |
| DE69835225D1 (de) | 2006-08-24 |
| DK1023074T3 (da) | 2006-11-06 |
| CN1528315A (zh) | 2004-09-15 |
| KR20010024431A (ko) | 2001-03-26 |
| NO20001744L (no) | 2000-04-05 |
| IL135469A0 (en) | 2001-05-20 |
| NO20001744D0 (no) | 2000-04-05 |
| CN1919199A (zh) | 2007-02-28 |
| CN1272788A (zh) | 2000-11-08 |
| AU747956B2 (en) | 2002-05-30 |
| IL135469A (en) | 2007-03-08 |
| KR20070032822A (ko) | 2007-03-22 |
| ATE332696T1 (de) | 2006-08-15 |
| EP1023074B1 (en) | 2006-07-12 |
| US6150349A (en) | 2000-11-21 |
| JP2009132743A (ja) | 2009-06-18 |
| JP2009051858A (ja) | 2009-03-12 |
| NZ503250A (en) | 2001-09-28 |
| CY1106330T1 (el) | 2011-10-12 |
| WO1999017779A1 (en) | 1999-04-15 |
| CN1187053C (zh) | 2005-02-02 |
| EP1023074A1 (en) | 2000-08-02 |
| ES2268792T3 (es) | 2007-03-16 |
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