NO326522B1 - Tricykliske og heterocykliske derivatforbindelser og farmasoytiske preparater inneholdende disse forbindelsene som den aktive bestanddel - Google Patents

Tricykliske og heterocykliske derivatforbindelser og farmasoytiske preparater inneholdende disse forbindelsene som den aktive bestanddel Download PDF

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Publication number
NO326522B1
NO326522B1 NO20032956A NO20032956A NO326522B1 NO 326522 B1 NO326522 B1 NO 326522B1 NO 20032956 A NO20032956 A NO 20032956A NO 20032956 A NO20032956 A NO 20032956A NO 326522 B1 NO326522 B1 NO 326522B1
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Norway
Prior art keywords
methyl
dihydro
methoxyphenyl
pyrazolo
cyclopenta
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NO20032956A
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English (en)
Norwegian (no)
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NO20032956D0 (no
NO20032956L (no
Inventor
Hisao Nakai
Yoshifumi Kagamiishi
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Ono Pharmaceutical Co
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Publication of NO20032956D0 publication Critical patent/NO20032956D0/no
Publication of NO20032956L publication Critical patent/NO20032956L/no
Publication of NO326522B1 publication Critical patent/NO326522B1/no

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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
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    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
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    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
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    • C07D—HETEROCYCLIC COMPOUNDS
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    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14—Ortho-condensed systems
NO20032956A 2000-12-28 2003-06-26 Tricykliske og heterocykliske derivatforbindelser og farmasoytiske preparater inneholdende disse forbindelsene som den aktive bestanddel NO326522B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2000402517 2000-12-28
PCT/JP2001/011581 WO2002053565A1 (fr) 2000-12-28 2001-12-27 Composes de derives tricycliques et heterocycliques et medicaments renfermant ces composes comme principe actif

Publications (3)

Publication Number Publication Date
NO20032956D0 NO20032956D0 (no) 2003-06-26
NO20032956L NO20032956L (no) 2003-08-28
NO326522B1 true NO326522B1 (no) 2008-12-22

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NO20032956A NO326522B1 (no) 2000-12-28 2003-06-26 Tricykliske og heterocykliske derivatforbindelser og farmasoytiske preparater inneholdende disse forbindelsene som den aktive bestanddel

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US (3) US7034153B2 (ru)
EP (2) EP1354884B1 (ru)
JP (2) JP3528968B2 (ru)
KR (1) KR100843281B1 (ru)
CN (2) CN1896076A (ru)
AT (2) ATE526330T1 (ru)
AU (1) AU2002226674B2 (ru)
BR (1) BR0116609A (ru)
CA (1) CA2432148C (ru)
CZ (1) CZ20031777A3 (ru)
DE (1) DE60130924T2 (ru)
DK (1) DK1354884T3 (ru)
ES (2) ES2294047T3 (ru)
HU (1) HUP0303653A3 (ru)
IL (2) IL156609A0 (ru)
MX (1) MXPA03005913A (ru)
NO (1) NO326522B1 (ru)
NZ (1) NZ526712A (ru)
PL (1) PL363381A1 (ru)
PT (1) PT1354884E (ru)
RU (1) RU2291869C2 (ru)
TW (1) TWI293630B (ru)
WO (1) WO2002053565A1 (ru)
ZA (1) ZA200305003B (ru)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6562965B1 (en) * 2000-07-06 2003-05-13 Bristol-Myers Squibb Pharma Company Convergent synthesis of α-aryl-β-ketonitriles
KR100843281B1 (ko) * 2000-12-28 2008-07-09 오노 야꾸힝 고교 가부시키가이샤 삼환식 복소환 유도체 화합물 및 그 화합물을 유효성분으로 하는 의약
UA80295C2 (en) * 2002-09-06 2007-09-10 Biogen Inc Pyrazolopyridines and using the same
US7129239B2 (en) 2002-10-28 2006-10-31 Pfizer Inc. Purine compounds and uses thereof
US7247628B2 (en) 2002-12-12 2007-07-24 Pfizer, Inc. Cannabinoid receptor ligands and uses thereof
US7329658B2 (en) 2003-02-06 2008-02-12 Pfizer Inc Cannabinoid receptor ligands and uses thereof
US7176210B2 (en) 2003-02-10 2007-02-13 Pfizer Inc. Cannabinoid receptor ligands and uses thereof
US7141669B2 (en) 2003-04-23 2006-11-28 Pfizer Inc. Cannabiniod receptor ligands and uses thereof
US7268133B2 (en) 2003-04-23 2007-09-11 Pfizer, Inc. Patent Department Cannabinoid receptor ligands and uses thereof
US7145012B2 (en) 2003-04-23 2006-12-05 Pfizer Inc. Cannabinoid receptor ligands and uses thereof
US7232823B2 (en) 2003-06-09 2007-06-19 Pfizer, Inc. Cannabinoid receptor ligands and uses thereof
US7872133B2 (en) * 2003-06-23 2011-01-18 Ono Pharmaceutical Co., Ltd. Tricyclic heterocycle compound
ATE478873T1 (de) 2003-06-25 2010-09-15 Ono Pharmaceutical Co Methansulfonsäuresalz einer pyrazolopyrimidinverbindung, kristall davon und verfahren zu deren herstellung
WO2005061508A1 (ja) * 2003-12-22 2005-07-07 Ono Pharmaceutical Co., Ltd. 三環式複素環化合物およびその化合物を有効成分とする医薬
WO2005087775A1 (ja) * 2004-03-15 2005-09-22 Ono Pharmaceutical Co., Ltd. 三環式複素環化合物およびその化合物を有効成分として含有する医薬組成物
DK1773345T3 (en) * 2004-06-30 2014-03-24 Athersys Inc NON-imidazol-tertiary amines AS HISTAMINE-3 receptor inhibitors in treating cognitive disorders, sleep disorders, obesity and other CNS DISORDERS
US7868037B2 (en) 2004-07-14 2011-01-11 Ptc Therapeutics, Inc. Methods for treating hepatitis C
BRPI0511834A (pt) 2004-07-14 2008-01-08 Ptc Therapeutics Inc métodos por tratar hepatite c
US7645881B2 (en) 2004-07-22 2010-01-12 Ptc Therapeutics, Inc. Methods for treating hepatitis C
AR051780A1 (es) * 2004-11-29 2007-02-07 Japan Tobacco Inc Compuestos en anillo fusionados que contienen nitrogeno y utilizacion de los mismos
JP4997976B2 (ja) * 2004-12-22 2012-08-15 小野薬品工業株式会社 三環式化合物およびその用途
TW200639163A (en) * 2005-02-04 2006-11-16 Genentech Inc RAF inhibitor compounds and methods
TW200936591A (en) * 2008-01-22 2009-09-01 Takeda Pharmaceutical Tricyclic compounds and use thereof
US8309559B2 (en) 2008-01-24 2012-11-13 Nikolay Filippovich Savchuk (EN) substituted 2-amino-3-sulfonyl-pyrazolo[1,5-A] pyrimidines/antagonists of serotonin 5-HT6 receptors, methods for the production and the use thereof
KR20130043207A (ko) * 2010-07-22 2013-04-29 자프겐 인크. 트리시클릭 화합물 및 이의 제조 및 사용 방법
WO2012047570A1 (en) * 2010-09-28 2012-04-12 Schering Corporation Fused tricyclic inhibitors of mammalian target of rapamycin
WO2012047569A1 (en) * 2010-09-28 2012-04-12 Schering Corporation Fused tricyclic inhibitors of mammalian target of rapamycin
SI2651902T1 (en) * 2010-12-17 2018-02-28 Reata Pharmaceuticals, Inc. Tricyclic pyrazolyl and pyrimidinylenones as antioxidant inflammatory modulators
WO2013046029A1 (en) 2011-09-30 2013-04-04 Ipsen Pharma S.A.S. Macrocyclic lrrk2 kinase inhibitors
CA2960777A1 (en) 2014-09-17 2016-03-24 Oncodesign S.A. Macrocyclic lrrk2 kinase inhibitors
US11220510B2 (en) 2018-04-09 2022-01-11 Incyte Corporation Pyrrole tricyclic compounds as A2A / A2B inhibitors
US11634433B2 (en) * 2019-12-03 2023-04-25 Turning Point Therapeutics, Inc. Macrocycles for use in treating disease

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0503099A4 (en) * 1990-10-09 1993-12-01 Otsuka Pharmaceutical Co., Ltd. Pyrimidine derivative, production thereof, and androgen inhibitor
KR100260292B1 (ko) 1995-09-28 2000-07-01 오쓰카 요시미쓰 진통제
EP0923582B1 (en) 1996-08-28 2006-09-20 Pfizer Inc. Substituted 6,5-hetero-bicyclic derivatives
EP1086103B1 (en) 1998-06-09 2003-05-02 Neurogen Corporation Pyrido 2,3-b]indolizine derivatives and aza analogues thereof; crf 1 specific ligands
DE69903333T2 (de) 1998-11-12 2003-08-07 Neurocrine Biosciences Inc Crf rezeptor-antagonisten und darauf bezogene methoden
DK1129096T3 (da) 1998-11-12 2003-09-15 Neurocrine Biosciences Inc CRF-receptorantagonister og fremgangsmåder, der er relateret dertil
KR100843281B1 (ko) * 2000-12-28 2008-07-09 오노 야꾸힝 고교 가부시키가이샤 삼환식 복소환 유도체 화합물 및 그 화합물을 유효성분으로 하는 의약

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