NO322479B1 - IL-6 mutein, fremgangsmate for fremstilling av muteinet, DNA-molekyl som koder for muteinet, samt vektor og vertscelle som inneholder DNA-molekylet og farmasoytisk blanding som omfatter muteinet. - Google Patents

IL-6 mutein, fremgangsmate for fremstilling av muteinet, DNA-molekyl som koder for muteinet, samt vektor og vertscelle som inneholder DNA-molekylet og farmasoytisk blanding som omfatter muteinet. Download PDF

Info

Publication number
NO322479B1
NO322479B1 NO19984697A NO984697A NO322479B1 NO 322479 B1 NO322479 B1 NO 322479B1 NO 19984697 A NO19984697 A NO 19984697A NO 984697 A NO984697 A NO 984697A NO 322479 B1 NO322479 B1 NO 322479B1
Authority
NO
Norway
Prior art keywords
mutein
human
polypeptide
vector
cells
Prior art date
Application number
NO19984697A
Other languages
English (en)
Norwegian (no)
Other versions
NO984697L (no
NO984697D0 (no
Inventor
Marc Ehlers
Stefan Rose-John
Joachim Grotzinger
Original Assignee
Applied Research Systems
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Research Systems filed Critical Applied Research Systems
Publication of NO984697L publication Critical patent/NO984697L/no
Publication of NO984697D0 publication Critical patent/NO984697D0/no
Publication of NO322479B1 publication Critical patent/NO322479B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]
    • C07K14/5412IL-6
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Rheumatology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Details Of Television Scanning (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Amplifiers (AREA)
NO19984697A 1996-04-09 1998-10-08 IL-6 mutein, fremgangsmate for fremstilling av muteinet, DNA-molekyl som koder for muteinet, samt vektor og vertscelle som inneholder DNA-molekylet og farmasoytisk blanding som omfatter muteinet. NO322479B1 (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CA002251355A CA2251355C (fr) 1996-04-09 1996-04-09 Muteine de il-6
CN96180247A CN1131309C (zh) 1996-04-09 1996-04-09 白细胞介素-6突变蛋白
PCT/EP1996/001506 WO1997038103A1 (fr) 1996-04-09 1996-04-09 Muteine de il-6
PCT/EP1997/001736 WO1997038104A1 (fr) 1996-04-09 1997-04-08 Muteine d'il-6

Publications (3)

Publication Number Publication Date
NO984697L NO984697L (no) 1998-10-08
NO984697D0 NO984697D0 (no) 1998-10-08
NO322479B1 true NO322479B1 (no) 2006-10-09

Family

ID=27170853

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19984697A NO322479B1 (no) 1996-04-09 1998-10-08 IL-6 mutein, fremgangsmate for fremstilling av muteinet, DNA-molekyl som koder for muteinet, samt vektor og vertscelle som inneholder DNA-molekylet og farmasoytisk blanding som omfatter muteinet.

Country Status (19)

Country Link
US (1) US6280975B1 (fr)
EP (1) EP0907737B1 (fr)
JP (1) JP4189866B2 (fr)
CN (1) CN1131309C (fr)
AT (1) ATE291087T1 (fr)
AU (1) AU728267B2 (fr)
BR (1) BR9708648B1 (fr)
CA (1) CA2251355C (fr)
DE (1) DE69634497T2 (fr)
DK (1) DK0907737T3 (fr)
EA (1) EA000852B1 (fr)
ES (1) ES2238690T3 (fr)
FI (1) FI982198A (fr)
HK (1) HK1019770A1 (fr)
IL (1) IL126484A0 (fr)
NO (1) NO322479B1 (fr)
PT (1) PT907737E (fr)
UA (1) UA72426C2 (fr)
WO (2) WO1997038103A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100374159C (zh) 1998-03-17 2008-03-12 中外制药株式会社 一种包含il-6拮抗剂活性成分的炎性肠道疾病的预防或治疗剂
KR20060119412A (ko) * 2005-05-20 2006-11-24 아주대학교산학협력단 IL-6 발현 억제를 위한 siRNA 및 이를 함유하는조성물
US8522915B2 (en) * 2007-12-19 2013-09-03 Westerngeco L.L.C. Method and system for selecting parameters of a seismic source array
CN102101885B (zh) * 2010-09-01 2013-06-05 南京发士达生物科技有限公司 低诱导抑制性t细胞的人白细胞介素ⅱ突变体及其用途

Also Published As

Publication number Publication date
CN1131309C (zh) 2003-12-17
HK1019770A1 (en) 2000-02-25
FI982198A0 (fi) 1998-10-09
EP0907737B1 (fr) 2005-03-16
IL126484A0 (en) 1999-08-17
NO984697L (no) 1998-10-08
BR9708648A (pt) 1999-08-03
US6280975B1 (en) 2001-08-28
WO1997038104A1 (fr) 1997-10-16
ATE291087T1 (de) 2005-04-15
EA000852B1 (ru) 2000-06-26
JP4189866B2 (ja) 2008-12-03
UA72426C2 (en) 2005-03-15
AU5686496A (en) 1997-10-29
WO1997038103A1 (fr) 1997-10-16
ES2238690T3 (es) 2005-09-01
EP0907737A1 (fr) 1999-04-14
EA199800914A1 (ru) 1999-04-29
NO984697D0 (no) 1998-10-08
PT907737E (pt) 2005-05-31
AU728267B2 (en) 2001-01-04
DE69634497D1 (de) 2005-04-21
DK0907737T3 (da) 2005-06-27
CA2251355C (fr) 2009-06-09
DE69634497T2 (de) 2006-01-26
FI982198A (fi) 1998-10-09
CN1216063A (zh) 1999-05-05
CA2251355A1 (fr) 1997-10-16
JP2000508164A (ja) 2000-07-04
BR9708648B1 (pt) 2011-02-08

Similar Documents

Publication Publication Date Title
KR100283541B1 (ko) 신규 사이토킨
US7211259B1 (en) 4-1BB polypeptides and DNA encoding 4-1BB polypeptides
AU694232B2 (en) Receptor for oncostatin M
JP3507507B2 (ja) 非免疫原性ペプチドを介して結合されたインターフェロン―αと免疫グロブリンとのハイブリッド
US7138500B1 (en) Antibodies to human 4-1BB
KR100453314B1 (ko) Cd40l 돌연변이 단백질
EP0547163B1 (fr) Polyligands de proteine joints a un noyau de proteine stable
EP0757099A2 (fr) Molécules CTLA4 mutées et leur utilisation
KR20190079636A (ko) 인터류킨 2 및 그로부터 유도된 단백질의 분비 수준을 증가시키는 방법
NO323197B1 (no) Fusjonsproteiner omfattende tumornekrosefaktorreseptor, DNA som koder for dette, fremgangsmate for fremstilling av dette samt farmasoytisk preparat.
NO20092448L (no) IL-17A/F-heterologe polypeptider og terapeutiske anvendelser derav
MXPA06010716A (es) Proteinas bouganin modificadas, citotoxinas y metodos y usos de las mismas.
JP2008019258A (ja) ヘテロ二量体を形成するハイブリッドタンパク質
Janknecht et al. Affinity purification of histidine-tagged proteins transiently produced in HeLa cells
WO1990010070A1 (fr) Analogues d'il-2 contenant des sites de glycosylation a liaison n
NO322479B1 (no) IL-6 mutein, fremgangsmate for fremstilling av muteinet, DNA-molekyl som koder for muteinet, samt vektor og vertscelle som inneholder DNA-molekylet og farmasoytisk blanding som omfatter muteinet.
JPH06220100A (ja) インターフェロン−α/β結合タンパク質、その製造法およびそれを含有する医薬組成物
EP0769055A1 (fr) Variantes du facteur inhibiteur de la leucemie
WO2001090382A2 (fr) Proteines de fusion agissant en tant que fas-ligand
WO2022188883A1 (fr) Protéine de fusion du récepteur tnfr2 et april baff
IL126484A (en) Il-6 mutein, its preparation and pharmaceutical compositions containing it

Legal Events

Date Code Title Description
CREP Change of representative

Representative=s name: ONSAGERS AS, POSTBOKS 6963 ST OLAVS PLASS, 0130 OS

CREP Change of representative

Representative=s name: BRYN AARFLOT AS, POSTBOKS 443 SENTRUM, 0104 OSLO,

MM1K Lapsed by not paying the annual fees