NO315304B1 - Fremgangsmate for fremstilling av et myseproteinhydrolysat - Google Patents
Fremgangsmate for fremstilling av et myseproteinhydrolysat Download PDFInfo
- Publication number
- NO315304B1 NO315304B1 NO19934310A NO934310A NO315304B1 NO 315304 B1 NO315304 B1 NO 315304B1 NO 19934310 A NO19934310 A NO 19934310A NO 934310 A NO934310 A NO 934310A NO 315304 B1 NO315304 B1 NO 315304B1
- Authority
- NO
- Norway
- Prior art keywords
- whey protein
- protein
- hydrolysis
- slurry
- protein hydrolyzate
- Prior art date
Links
- 108010046377 Whey Proteins Proteins 0.000 title claims abstract description 60
- 102000007544 Whey Proteins Human genes 0.000 title claims abstract description 60
- 235000021119 whey protein Nutrition 0.000 title claims abstract description 59
- 239000003531 protein hydrolysate Substances 0.000 title claims abstract description 49
- 238000004519 manufacturing process Methods 0.000 title claims description 7
- 238000000034 method Methods 0.000 claims abstract description 49
- 238000006460 hydrolysis reaction Methods 0.000 claims abstract description 32
- 230000007062 hydrolysis Effects 0.000 claims abstract description 31
- 239000012466 permeate Substances 0.000 claims abstract description 21
- 239000002002 slurry Substances 0.000 claims abstract description 18
- 238000010438 heat treatment Methods 0.000 claims abstract description 16
- 238000000108 ultra-filtration Methods 0.000 claims abstract description 16
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 13
- 108091005804 Peptidases Proteins 0.000 claims abstract description 7
- 239000004365 Protease Substances 0.000 claims abstract description 7
- 241000194108 Bacillus licheniformis Species 0.000 claims abstract description 3
- 235000014469 Bacillus subtilis Nutrition 0.000 claims abstract description 3
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 claims abstract 3
- 230000000415 inactivating effect Effects 0.000 claims abstract 2
- 235000018102 proteins Nutrition 0.000 claims description 41
- 102000004169 proteins and genes Human genes 0.000 claims description 41
- 108090000623 proteins and genes Proteins 0.000 claims description 41
- 102000004190 Enzymes Human genes 0.000 claims description 35
- 108090000790 Enzymes Proteins 0.000 claims description 35
- 230000029219 regulation of pH Effects 0.000 claims description 14
- 239000000203 mixture Substances 0.000 claims description 13
- AXCZMVOFGPJBDE-UHFFFAOYSA-L calcium dihydroxide Chemical compound [OH-].[OH-].[Ca+2] AXCZMVOFGPJBDE-UHFFFAOYSA-L 0.000 claims description 11
- 239000000920 calcium hydroxide Substances 0.000 claims description 11
- 229910001861 calcium hydroxide Inorganic materials 0.000 claims description 11
- 235000011116 calcium hydroxide Nutrition 0.000 claims description 11
- 239000000047 product Substances 0.000 claims description 8
- 238000001471 micro-filtration Methods 0.000 claims description 5
- 239000000126 substance Substances 0.000 claims description 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract description 36
- 238000001728 nano-filtration Methods 0.000 abstract description 22
- 102000035195 Peptidases Human genes 0.000 abstract description 4
- 238000002156 mixing Methods 0.000 abstract description 2
- 230000008020 evaporation Effects 0.000 abstract 1
- 238000001704 evaporation Methods 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 239000012141 concentrate Substances 0.000 description 39
- 238000001694 spray drying Methods 0.000 description 16
- 239000006227 byproduct Substances 0.000 description 15
- 239000012465 retentate Substances 0.000 description 15
- 108010009355 microbial metalloproteinases Proteins 0.000 description 14
- 229910052799 carbon Inorganic materials 0.000 description 10
- 239000007795 chemical reaction product Substances 0.000 description 9
- 238000009928 pasteurization Methods 0.000 description 9
- 239000007858 starting material Substances 0.000 description 9
- 102000005158 Subtilisins Human genes 0.000 description 8
- 108010056079 Subtilisins Proteins 0.000 description 8
- 230000000721 bacterilogical effect Effects 0.000 description 8
- 238000012512 characterization method Methods 0.000 description 8
- 239000008367 deionised water Substances 0.000 description 8
- 229910021641 deionized water Inorganic materials 0.000 description 8
- 238000011026 diafiltration Methods 0.000 description 8
- 238000001035 drying Methods 0.000 description 8
- 230000007071 enzymatic hydrolysis Effects 0.000 description 8
- 238000006047 enzymatic hydrolysis reaction Methods 0.000 description 8
- 238000011534 incubation Methods 0.000 description 8
- 239000012528 membrane Substances 0.000 description 8
- 239000002994 raw material Substances 0.000 description 8
- 239000007787 solid Substances 0.000 description 8
- 239000007921 spray Substances 0.000 description 8
- 238000011146 sterile filtration Methods 0.000 description 8
- 241000894006 Bacteria Species 0.000 description 7
- 230000003247 decreasing effect Effects 0.000 description 7
- 238000004090 dissolution Methods 0.000 description 7
- 238000000926 separation method Methods 0.000 description 7
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 6
- 230000009849 deactivation Effects 0.000 description 6
- 238000001914 filtration Methods 0.000 description 6
- 230000035484 reaction time Effects 0.000 description 6
- 230000007065 protein hydrolysis Effects 0.000 description 5
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 description 2
- 102000004142 Trypsin Human genes 0.000 description 2
- 108090000631 Trypsin Proteins 0.000 description 2
- 230000002378 acidificating effect Effects 0.000 description 2
- 239000012467 final product Substances 0.000 description 2
- 239000012588 trypsin Substances 0.000 description 2
- FBEHFRAORPEGFH-UHFFFAOYSA-N Allyxycarb Chemical compound CNC(=O)OC1=CC(C)=C(N(CC=C)CC=C)C(C)=C1 FBEHFRAORPEGFH-UHFFFAOYSA-N 0.000 description 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 1
- 239000005862 Whey Substances 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 235000013361 beverage Nutrition 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 235000013351 cheese Nutrition 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 230000002779 inactivation Effects 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 235000010755 mineral Nutrition 0.000 description 1
- 238000010979 pH adjustment Methods 0.000 description 1
- 230000002797 proteolythic effect Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 229910000029 sodium carbonate Inorganic materials 0.000 description 1
- 239000001488 sodium phosphate Substances 0.000 description 1
- 229910000162 sodium phosphate Inorganic materials 0.000 description 1
- 238000005063 solubilization Methods 0.000 description 1
- 230000007928 solubilization Effects 0.000 description 1
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 description 1
- 238000013060 ultrafiltration and diafiltration Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
- A23J3/00—Working-up of proteins for foodstuffs
- A23J3/30—Working-up of proteins for foodstuffs by hydrolysis
- A23J3/32—Working-up of proteins for foodstuffs by hydrolysis using chemical agents
- A23J3/34—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes
- A23J3/341—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes of animal proteins
- A23J3/343—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes of animal proteins of dairy proteins
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Dairy Products (AREA)
- Peptides Or Proteins (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Non-Alcoholic Beverages (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP91610049 | 1991-05-31 | ||
| PCT/DK1992/000170 WO1992021248A1 (en) | 1991-05-31 | 1992-05-27 | Method for production of a whey protein hydrolyzate |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO934310L NO934310L (no) | 1993-11-29 |
| NO934310D0 NO934310D0 (no) | 1993-11-29 |
| NO315304B1 true NO315304B1 (no) | 2003-08-18 |
Family
ID=8208779
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19934310A NO315304B1 (no) | 1991-05-31 | 1993-11-29 | Fremgangsmate for fremstilling av et myseproteinhydrolysat |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5691165A (ja) |
| EP (1) | EP0588841B1 (ja) |
| JP (1) | JP3167723B2 (ja) |
| KR (1) | KR100237147B1 (ja) |
| AT (1) | ATE146657T1 (ja) |
| AU (1) | AU656977B2 (ja) |
| CA (1) | CA2109584C (ja) |
| DE (1) | DE69216231T2 (ja) |
| DK (1) | DK0588841T3 (ja) |
| ES (1) | ES2097328T3 (ja) |
| IE (1) | IE77641B1 (ja) |
| IL (1) | IL102059A (ja) |
| NO (1) | NO315304B1 (ja) |
| NZ (1) | NZ242963A (ja) |
| RU (1) | RU2084172C1 (ja) |
| WO (1) | WO1992021248A1 (ja) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH683695A5 (fr) * | 1992-04-09 | 1994-04-29 | Nestle Sa | Hydrolyse enzymatique. |
| DK71292D0 (ja) * | 1992-05-27 | 1992-05-27 | Novo Nordisk As | |
| FI94089C (fi) * | 1992-12-10 | 1995-07-25 | Valio Oy | Menetelmä allergiaa aiheuttavien yhdisteiden poistamiseksi proteiinipitoisista koostumuksista |
| AU692612B2 (en) * | 1994-10-14 | 1998-06-11 | Morinaga Milk Industry Company Limited | Peptide mixture and products thereof |
| WO1997001966A1 (en) * | 1995-06-30 | 1997-01-23 | Md Foods Amba | A method of producing a peptide mixture |
| ATE275831T1 (de) | 1998-06-17 | 2004-10-15 | New Zealand Dairy Board | Bioaktive molke-eiweisshydrolysate |
| US6120820A (en) * | 1999-02-22 | 2000-09-19 | Land O'lakes, Inc. | Method of modifying the color of a dairy material |
| US6416796B1 (en) | 1999-04-27 | 2002-07-09 | Kraft Foods, Inc. | Whey protein digestion products in cheese |
| US6551636B2 (en) | 1999-07-23 | 2003-04-22 | Novozymes A/S | Modification of foaming properties of proteins |
| NZ518223A (en) * | 2000-08-11 | 2004-11-26 | Novozymes North America Inc | Whey protein emulsion |
| NZ506866A (en) | 2000-09-11 | 2003-05-30 | New Zealand Dairy Board | Bioactive whey protein hydrolysate free of bitter flavours wherein the enzyme used is a heat labile protease |
| US20030078393A1 (en) * | 2001-09-13 | 2003-04-24 | Novozymes Biotech, Inc. | Methods for producing coagulated whey protein |
| US20040047947A1 (en) * | 2002-02-21 | 2004-03-11 | Scott Bloomer | Method of preparing a milk polar lipid and a sphingolipid enriched concentrate |
| US20030224096A1 (en) * | 2002-06-04 | 2003-12-04 | Novozymes A/S | Whey protein hydrolysate |
| TWI317636B (en) * | 2002-11-22 | 2009-12-01 | Meiji Dairies Corp | Nutritional compositions for liver disease patients or for patients underhigh levels of invasive stress |
| US7399496B2 (en) * | 2003-02-07 | 2008-07-15 | Glanbia Nutritionals (Ireland) Limited | Hydrolyzed whey protein compositions |
| US7582326B2 (en) * | 2003-10-29 | 2009-09-01 | Kraft Foods Global Brands Llc | Method of deflavoring whey protein using membrane electrodialysis |
| NO320964B1 (no) * | 2004-05-26 | 2006-02-20 | Norcape Biotechnology As | Hydrolysert marint proteinprodukt og et fôrprodukt omfattende dette, fremgangsmate for fremstilling og anvendelse |
| WO2007143794A1 (en) | 2006-06-15 | 2007-12-21 | Murray Goulburn Co-Operative Co. Limited | Formulation comprising whey protein and hydrolysates for improving muscle recovery |
| US8222372B2 (en) * | 2007-04-16 | 2012-07-17 | Novozymes A/S | Whey protein hydrolysate |
| US9034402B2 (en) * | 2007-04-16 | 2015-05-19 | Solae, Llc | Protein hydrolysate compositions having improved sensory characteristics and physical properties |
| US9055752B2 (en) * | 2008-11-06 | 2015-06-16 | Intercontinental Great Brands Llc | Shelf-stable concentrated dairy liquids and methods of forming thereof |
| RU2011133071A (ru) * | 2009-01-06 | 2013-02-20 | Нестек С.А. | Переработка макронутриентов |
| CA2773686C (en) * | 2009-04-02 | 2018-01-16 | Novozymes A/S | Process for making a milk-based protein hydrolysate |
| JP5177901B2 (ja) * | 2009-12-02 | 2013-04-10 | 株式会社明治 | 栄養組成物 |
| UA112972C2 (uk) | 2010-09-08 | 2016-11-25 | Інтерконтінентал Грейт Брендс ЛЛС | Рідкий молочний концентрат з високим вмістом сухих речовин |
| RU2457689C2 (ru) * | 2010-11-17 | 2012-08-10 | Государственное образовательное учреждение высшего профессионального образования " Кемеровский технологический институт пищевой промышленности" | Способ получения смеси аминокислот из отходов переработки сырья животного или растительного происхождения |
| CZ306184B6 (cs) * | 2010-12-30 | 2016-09-14 | C2P S.R.O. | Způsob výroby hydrolyzátu kvasničné bílkoviny |
| JP5763024B2 (ja) * | 2012-09-07 | 2015-08-12 | 株式会社明治 | 栄養組成物 |
| EP2883457B1 (de) * | 2013-12-10 | 2017-02-15 | DMK Deutsches Milchkontor GmbH | Vorrichtung und Verfahren zur kontinuierlichen Herstellung von Proteinhydrolysaten |
| EP3197288A4 (en) * | 2015-07-15 | 2018-05-16 | Scotland, Rebecca | Isolation of plant oligopeptides and uses thereof |
| KR101698379B1 (ko) * | 2015-09-17 | 2017-01-20 | 삼육대학교산학협력단 | 산양유 단백질 가수분해물, 그것의 제조방법 및 그것의 식품에 사용하는 용도 |
| US20170127698A1 (en) | 2015-10-02 | 2017-05-11 | Michael J. Young | Protein Hydrolysate, Method for Making, and Use |
| RU2663583C2 (ru) * | 2015-12-30 | 2018-08-07 | Федеральное государственное бюджетное научное учреждение "Федеральный научный центр пищевых систем им. В.М. Горбатова" РАН | Способ производства гидролизата сывороточных белков |
| CN108949876B (zh) * | 2018-07-09 | 2020-11-24 | 齐鲁工业大学 | 一种具有抗氧化活性的牡丹籽多肽口服液的制备方法 |
| CN112888313A (zh) * | 2018-10-26 | 2021-06-01 | 株式会社明治 | 高蛋白质的乳原料的制造方法 |
| AU2019364074A1 (en) * | 2018-10-26 | 2021-05-20 | Meiji Co., Ltd. | Method for producing high-protein milk raw material |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2459620B1 (fr) * | 1979-06-26 | 1983-08-05 | Agronomique Inst Nat Rech | Hydrolisat enzymatique total de proteines de lactoserum, obtention et application |
| EP0065663A1 (en) * | 1981-05-11 | 1982-12-01 | Miles Laboratories, Inc. | Method for the preparation of a protein hydrolyzate from whey protein |
| US4636388A (en) * | 1982-02-22 | 1987-01-13 | Stauffer Chemical Company | Preparing protein for hydrolysis and product |
| DK589785A (da) * | 1985-12-18 | 1987-06-19 | Samuelsson Ernst Gunnar | Peptidpraeparat, fremgangsmaade til fremstilling deraf samt anvendelse af peptidpraeparatet |
| FR2608051B1 (fr) * | 1986-12-15 | 1989-04-07 | Bellon Labor Sa Roger | Procede de fabrication d'un hydrolysat enzymatique de proteines riche en di- et tri-peptides, utilisable notamment en nutrition artificielle et en dietetique |
| EP0322589B1 (fr) * | 1987-12-23 | 1993-01-20 | Societe Des Produits Nestle S.A. | Procédé de préparation d'un hydrolysat de protéines de lactosérum et d'un aliment hypoallergéniques |
| BE1003298A3 (nl) * | 1990-01-12 | 1992-02-18 | Tessenderlo Chem Nv | Werkwijze voor het bereiden van een enzymatisch hydrolysaat. |
| DK3991D0 (da) * | 1991-01-10 | 1991-01-10 | Novo Nordisk As | Fremgangsmaade til fremstilling af et proteinhydrolysat |
-
1992
- 1992-05-27 AU AU18827/92A patent/AU656977B2/en not_active Expired
- 1992-05-27 WO PCT/DK1992/000170 patent/WO1992021248A1/en active IP Right Grant
- 1992-05-27 EP EP92911154A patent/EP0588841B1/en not_active Expired - Lifetime
- 1992-05-27 DK DK92911154.0T patent/DK0588841T3/da active
- 1992-05-27 DE DE69216231T patent/DE69216231T2/de not_active Expired - Lifetime
- 1992-05-27 RU RU9293058581A patent/RU2084172C1/ru active
- 1992-05-27 CA CA002109584A patent/CA2109584C/en not_active Expired - Lifetime
- 1992-05-27 KR KR1019930703670A patent/KR100237147B1/ko not_active IP Right Cessation
- 1992-05-27 AT AT92911154T patent/ATE146657T1/de not_active IP Right Cessation
- 1992-05-27 US US08/157,074 patent/US5691165A/en not_active Expired - Fee Related
- 1992-05-27 ES ES92911154T patent/ES2097328T3/es not_active Expired - Lifetime
- 1992-05-27 JP JP51039292A patent/JP3167723B2/ja not_active Expired - Lifetime
- 1992-05-29 NZ NZ242963A patent/NZ242963A/en not_active IP Right Cessation
- 1992-05-29 IL IL10205992A patent/IL102059A/xx not_active IP Right Cessation
- 1992-07-01 IE IE921762A patent/IE77641B1/en not_active IP Right Cessation
-
1993
- 1993-11-29 NO NO19934310A patent/NO315304B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0588841A1 (en) | 1994-03-30 |
| DK0588841T3 (da) | 1997-05-12 |
| WO1992021248A1 (en) | 1992-12-10 |
| NZ242963A (en) | 1993-10-26 |
| CA2109584A1 (en) | 1992-12-10 |
| AU1882792A (en) | 1993-01-08 |
| IL102059A (en) | 1997-02-18 |
| DE69216231D1 (de) | 1997-02-06 |
| NO934310L (no) | 1993-11-29 |
| DE69216231T2 (de) | 1997-06-12 |
| IE77641B1 (en) | 1997-12-31 |
| AU656977B2 (en) | 1995-02-23 |
| US5691165A (en) | 1997-11-25 |
| JPH06507547A (ja) | 1994-09-01 |
| RU2084172C1 (ru) | 1997-07-20 |
| CA2109584C (en) | 2003-04-01 |
| ATE146657T1 (de) | 1997-01-15 |
| EP0588841B1 (en) | 1996-12-27 |
| NO934310D0 (no) | 1993-11-29 |
| IE921762A1 (en) | 1992-12-02 |
| KR100237147B1 (ko) | 2000-01-15 |
| IL102059A0 (en) | 1992-12-30 |
| ES2097328T3 (es) | 1997-04-01 |
| JP3167723B2 (ja) | 2001-05-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK1K | Patent expired |