NO314486B1 - Anvendelse av et antidepressivt middel i kombinasjon med fenylalanin ellertyrosin for tillaging av medisin for behandling av multippelsklerose eller andre demyelinerende tilstander, samt et kombinasjonspreparat og enenhetsdoseform - Google Patents
Anvendelse av et antidepressivt middel i kombinasjon med fenylalanin ellertyrosin for tillaging av medisin for behandling av multippelsklerose eller andre demyelinerende tilstander, samt et kombinasjonspreparat og enenhetsdoseform Download PDFInfo
- Publication number
- NO314486B1 NO314486B1 NO19971539A NO971539A NO314486B1 NO 314486 B1 NO314486 B1 NO 314486B1 NO 19971539 A NO19971539 A NO 19971539A NO 971539 A NO971539 A NO 971539A NO 314486 B1 NO314486 B1 NO 314486B1
- Authority
- NO
- Norway
- Prior art keywords
- phenylalanine
- lofepramine
- preparation
- tyrosine
- antidepressant
- Prior art date
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/688—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols both hydroxy compounds having nitrogen atoms, e.g. sphingomyelins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7135—Compounds containing heavy metals
- A61K31/714—Cobalamins, e.g. cyanocobalamin, i.e. vitamin B12
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
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- Medicinal Chemistry (AREA)
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- General Health & Medical Sciences (AREA)
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- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
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- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Molecular Biology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Hospice & Palliative Care (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Control Of El Displays (AREA)
- Control Of Indicators Other Than Cathode Ray Tubes (AREA)
- Fodder In General (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9420116A GB9420116D0 (en) | 1994-10-05 | 1994-10-05 | A therapeutic drug treatment for compensating for the effects of nerve damage caused by multiple sclerosis and other demyelinating conditions |
| GBGB9508482.8A GB9508482D0 (en) | 1995-04-26 | 1995-04-26 | A therapeutic drug treatment for compensating for the effects of nerve damage caused by multiple sclerosis and other demyelinating conditions, and the product |
| PCT/GB1995/002361 WO1996011009A1 (en) | 1994-10-05 | 1995-10-05 | Treatment of multiple sclerosis (ms) and other demyelinating conditions using lofepramine in combination with l-phenylalanine, tyrosine or tryptophan and possibly a vitamin b12 compound |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO971539D0 NO971539D0 (no) | 1997-04-04 |
| NO971539L NO971539L (no) | 1997-04-04 |
| NO314486B1 true NO314486B1 (no) | 2003-03-31 |
Family
ID=26305745
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19971539A NO314486B1 (no) | 1994-10-05 | 1997-04-04 | Anvendelse av et antidepressivt middel i kombinasjon med fenylalanin ellertyrosin for tillaging av medisin for behandling av multippelsklerose eller andre demyelinerende tilstander, samt et kombinasjonspreparat og enenhetsdoseform |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US6096737A (de) |
| EP (1) | EP0784476B1 (de) |
| JP (1) | JPH10508583A (de) |
| AT (1) | ATE227124T1 (de) |
| AU (1) | AU710339B2 (de) |
| CA (1) | CA2200761C (de) |
| CZ (1) | CZ293873B6 (de) |
| DE (1) | DE69528773T2 (de) |
| DK (1) | DK0784476T3 (de) |
| ES (1) | ES2184808T3 (de) |
| FI (1) | FI116659B (de) |
| HU (1) | HU225493B1 (de) |
| IS (1) | IS1956B (de) |
| NO (1) | NO314486B1 (de) |
| NZ (1) | NZ293642A (de) |
| PL (1) | PL181802B1 (de) |
| PT (1) | PT784476E (de) |
| SK (1) | SK281932B6 (de) |
| WO (1) | WO1996011009A1 (de) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6335323B2 (en) * | 1996-07-05 | 2002-01-01 | The Wwk Trust | Compositions for the treatment of peripheral neuropathies containing antidepressants and/or monoamine oxidase inhibitors and/or vitamin B12 and/or precursors or inducers of a neurotransmitter |
| GB9617990D0 (en) | 1996-08-29 | 1996-10-09 | Scotia Holdings Plc | Treatment of pain |
| EP0835660A1 (de) * | 1996-10-14 | 1998-04-15 | Gaston Edmond Filomena Merckx | Zusammensetzungen enthaltend Methylcobalamin für die Behandlung von Muliple Sklerosis oder andere demyleinisierende Krankheiten |
| US7232830B2 (en) * | 1998-06-26 | 2007-06-19 | Elaine A Delack | Method for treatment of neurodegenerative diseases and effects of aging |
| GB9904252D0 (en) * | 1999-02-24 | 1999-04-21 | Worsley Andrew P | Composition for the treatment of pain |
| GB9906808D0 (en) * | 1999-03-24 | 1999-05-19 | Kilgowan Limited | Formulation for treatment of pain |
| GB2355191A (en) * | 1999-10-12 | 2001-04-18 | Laxdale Ltd | Combination formulations for fatigue, head injury and strokes |
| CA2774959C (en) * | 2000-08-04 | 2016-05-31 | Dmi Biosciences, Inc. | Method of using diketopiperazines and composition containing them |
| US8394813B2 (en) | 2000-11-14 | 2013-03-12 | Shire Llc | Active agent delivery systems and methods for protecting and administering active agents |
| US20020147206A1 (en) * | 2001-04-05 | 2002-10-10 | Pfizer Inc. | Combination treatment of multiple sclerosis (MS), other demyelinating conditions and peripheral neuropathy, especially painful neuropathies and diabetic neuropathy |
| GB0216027D0 (en) | 2002-07-10 | 2002-08-21 | Arachnova Therapeutics Ltd | New therapeutic use |
| US7169752B2 (en) * | 2003-09-30 | 2007-01-30 | New River Pharmaceuticals Inc. | Compounds and compositions for prevention of overdose of oxycodone |
| US6833142B2 (en) * | 2002-03-14 | 2004-12-21 | Duane Bennett | Formulation for the prevention and treatment of multiple sclerosis and other demyelinating conditions |
| EP1571970B1 (de) | 2002-10-02 | 2011-08-17 | DMI Biosciences, Inc. | Diagnose und überwachung von krankheiten |
| PL378108A1 (pl) * | 2003-02-14 | 2006-03-06 | Combinatorx, Incorporated | Leczenie łączone do terapii zapalnych zaburzeń immunologicznych |
| CN103191409A (zh) | 2003-05-15 | 2013-07-10 | Dmi生物科学公司 | T-细胞介导的疾病的治疗 |
| GB0313630D0 (en) * | 2003-06-12 | 2003-07-16 | Wwk Trust The | Compositions for the enhanced treatment of depression |
| US20050192261A1 (en) * | 2003-09-15 | 2005-09-01 | Jost-Price Edward R. | Methods and reagents for the treatment of immunoinflammatory disorders |
| US20110136742A1 (en) * | 2006-02-24 | 2011-06-09 | Travis Mickle | Antidepressant prodrugs |
| US8217047B2 (en) * | 2008-05-27 | 2012-07-10 | Dmi Acquisition Corp. | Therapeutic methods and compounds |
| WO2011011594A2 (en) * | 2009-07-23 | 2011-01-27 | Shriners Hospitals For Children | Intracellular toll-like receptors pathways and axonal degeneration |
| CA2810844C (en) | 2010-09-07 | 2017-03-21 | Dmi Acquisition Corp. | Diketopiperazine compositions for the treatment of metabolic syndrome and related conditions |
| EA027343B1 (ru) | 2011-10-10 | 2017-07-31 | Ампио Фармасьютикалз, Инк. | Имплантируемые устройства медицинского назначения с повышенной иммунной толерантностью и способы изготовления и имплантирования |
| CN104958752B (zh) | 2011-10-10 | 2019-01-18 | 安皮奥制药股份有限公司 | 退行性关节病的治疗 |
| JP6231484B2 (ja) | 2011-10-28 | 2017-11-15 | アンピオ ファーマシューティカルズ，インコーポレイテッド | 鼻炎の処置 |
| KR20150132508A (ko) | 2013-03-15 | 2015-11-25 | 앰피오 파마슈티컬스 인코퍼레이티드 | 줄기세포의 가동화, 회귀, 증식 및 분화를 위한 조성물 및 이의 사용 방법 |
| KR20170045274A (ko) | 2014-08-18 | 2017-04-26 | 앰피오 파마슈티컬스 인코퍼레이티드 | 관절 징후의 치료 |
| EP3310375A4 (de) | 2015-06-22 | 2019-02-20 | Ampio Pharmaceuticals, Inc. | Verwendung von niedermolekularen fraktionen von humanem serumalbumin bei der behandlung von erkrankungen |
| WO2017085437A1 (en) | 2015-11-19 | 2017-05-26 | The Wwk Trust | Combinations for the treatment of dementia, and the enhancement of cognitive function |
| US20190262353A1 (en) * | 2016-10-25 | 2019-08-29 | Uti Limited Partnership | Treatment for progressive multiple sclerosis |
| EP3615053A4 (de) | 2017-04-25 | 2021-07-14 | Temple Otorongo LLC | Pharmazeutische zusammensetzung mit tryptophan- und phyllokininderivat zur verwendung in der behandlung von psychiatrischen und psychologischen störungen |
| EP3431491A1 (de) * | 2017-07-18 | 2019-01-23 | Centre National De La Recherche Scientifique | Verfahren zur reinigung von proteinen mit einer tubulin-carboxypeptidase-aktivität und peptidbasierten inhibitoren davon |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1497306A (en) * | 1975-07-03 | 1978-01-05 | Leo Ab | Preparation of lofepramine and its hydrochloride |
| GB2082910A (en) * | 1980-08-28 | 1982-03-17 | Berk Pharmaceuticals Ltd | Anti-depressant compositions |
| US4409243A (en) * | 1981-11-09 | 1983-10-11 | Julian Lieb | Treatment of auto-immune and inflammatory diseases |
| GB2129299A (en) * | 1982-11-09 | 1984-05-16 | Alec James Coppen | Pharmaceutical compositions |
| DE3519687A1 (de) * | 1985-06-01 | 1986-12-04 | Veit Arend | Aminosaeuren enthaltendes arzneimittel |
| US4650789A (en) * | 1985-10-15 | 1987-03-17 | Commonwealth Medical Corporation Of America | Method and composition for increasing production of serotonin |
| US4843071A (en) * | 1986-12-05 | 1989-06-27 | Serotonin Industries Of Charleston | Method and composition for treating obesity, drug abuse, and narcolepsy |
| DE4204102C2 (de) * | 1992-02-12 | 1998-09-24 | Kragler Peter | Arzneimittel zur Behandlung und/oder Prophylaxe von AIDS und anderen verwandten Erkrankungen |
-
1995
- 1995-10-05 EP EP95933488A patent/EP0784476B1/de not_active Expired - Lifetime
- 1995-10-05 CA CA002200761A patent/CA2200761C/en not_active Expired - Fee Related
- 1995-10-05 DE DE69528773T patent/DE69528773T2/de not_active Expired - Lifetime
- 1995-10-05 JP JP8512415A patent/JPH10508583A/ja active Pending
- 1995-10-05 AU AU36126/95A patent/AU710339B2/en not_active Ceased
- 1995-10-05 DK DK95933488T patent/DK0784476T3/da active
- 1995-10-05 HU HU9702373A patent/HU225493B1/hu not_active IP Right Cessation
- 1995-10-05 SK SK438-97A patent/SK281932B6/sk not_active IP Right Cessation
- 1995-10-05 AT AT95933488T patent/ATE227124T1/de not_active IP Right Cessation
- 1995-10-05 WO PCT/GB1995/002361 patent/WO1996011009A1/en active IP Right Grant
- 1995-10-05 CZ CZ1997995A patent/CZ293873B6/cs not_active IP Right Cessation
- 1995-10-05 PT PT95933488T patent/PT784476E/pt unknown
- 1995-10-05 ES ES95933488T patent/ES2184808T3/es not_active Expired - Lifetime
- 1995-10-05 NZ NZ293642A patent/NZ293642A/xx not_active IP Right Cessation
- 1995-10-05 PL PL95319830A patent/PL181802B1/pl not_active IP Right Cessation
- 1995-10-05 US US08/817,086 patent/US6096737A/en not_active Expired - Lifetime
-
1997
- 1997-03-26 FI FI971290A patent/FI116659B/fi active IP Right Grant
- 1997-03-26 IS IS4454A patent/IS1956B/is unknown
- 1997-04-04 NO NO19971539A patent/NO314486B1/no not_active IP Right Cessation
-
2000
- 2000-06-01 US US09/584,401 patent/US6569850B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| SK43897A3 (en) | 1998-08-05 |
| DK0784476T3 (da) | 2003-03-17 |
| CA2200761C (en) | 2008-02-26 |
| ATE227124T1 (de) | 2002-11-15 |
| ES2184808T3 (es) | 2003-04-16 |
| JPH10508583A (ja) | 1998-08-25 |
| PL319830A1 (en) | 1997-09-01 |
| PT784476E (pt) | 2003-03-31 |
| SK281932B6 (sk) | 2001-09-11 |
| HU225493B1 (en) | 2007-01-29 |
| CA2200761A1 (en) | 1996-04-18 |
| US6569850B1 (en) | 2003-05-27 |
| US6096737A (en) | 2000-08-01 |
| IS1956B (is) | 2004-11-15 |
| NO971539D0 (no) | 1997-04-04 |
| IS4454A (is) | 1997-03-26 |
| AU710339B2 (en) | 1999-09-16 |
| NO971539L (no) | 1997-04-04 |
| DE69528773D1 (de) | 2002-12-12 |
| CZ99597A3 (en) | 1997-11-12 |
| WO1996011009A1 (en) | 1996-04-18 |
| FI971290A0 (fi) | 1997-03-26 |
| EP0784476A1 (de) | 1997-07-23 |
| NZ293642A (en) | 1998-10-28 |
| FI116659B (fi) | 2006-01-31 |
| HUT77380A (hu) | 1998-04-28 |
| PL181802B1 (en) | 2001-09-28 |
| DE69528773T2 (de) | 2003-09-04 |
| AU3612695A (en) | 1996-05-02 |
| FI971290A (fi) | 1997-06-02 |
| EP0784476B1 (de) | 2002-11-06 |
| CZ293873B6 (cs) | 2004-08-18 |
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| MM1K | Lapsed by not paying the annual fees |