NO313538B1 - Anvendelse av citicolin samt farmasöytisk preparat - Google Patents
Anvendelse av citicolin samt farmasöytisk preparat Download PDFInfo
- Publication number
- NO313538B1 NO313538B1 NO19974076A NO974076A NO313538B1 NO 313538 B1 NO313538 B1 NO 313538B1 NO 19974076 A NO19974076 A NO 19974076A NO 974076 A NO974076 A NO 974076A NO 313538 B1 NO313538 B1 NO 313538B1
- Authority
- NO
- Norway
- Prior art keywords
- citicoline
- stroke
- pharmaceutically acceptable
- around
- approx
- Prior art date
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- CGPUWJWCVCFERF-UHFFFAOYSA-N staurosporine Natural products C12=C3N4C5=CC=CC=C5C3=C3CNC(=O)C3=C2C2=CC=CC=C2N1C1CC(NC)C(OC)C4(OC)O1 CGPUWJWCVCFERF-UHFFFAOYSA-N 0.000 description 1
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- PHWBOXQYWZNQIN-UHFFFAOYSA-N ticlopidine Chemical compound ClC1=CC=CC=C1CN1CC(C=CS2)=C2CC1 PHWBOXQYWZNQIN-UHFFFAOYSA-N 0.000 description 1
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- RBKASMJPSJDQKY-RBFSKHHSSA-N tirilazad Chemical compound O=C([C@@H]1[C@@]2(C)CC=C3[C@@]4(C)C=CC(=O)C=C4CC[C@H]3[C@@H]2C[C@H]1C)CN(CC1)CCN1C(N=1)=CC(N2CCCC2)=NC=1N1CCCC1 RBKASMJPSJDQKY-RBFSKHHSSA-N 0.000 description 1
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- DBTJWGHAMYSWQR-OLMHPWOBSA-K trisodium;hydron;[(2r,3s,4s)-3,4,5-trihydroxy-5-(phosphonatooxymethyl)oxolan-2-yl]methyl phosphate;octahydrate Chemical compound [H+].O.O.O.O.O.O.O.O.[Na+].[Na+].[Na+].O[C@H]1[C@H](O)C(O)(COP([O-])([O-])=O)O[C@@H]1COP([O-])([O-])=O DBTJWGHAMYSWQR-OLMHPWOBSA-K 0.000 description 1
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- JWOSSISWAJNJIA-UHFFFAOYSA-N vinconate Chemical compound C12=CC=CC=C2C2=C3N1C(C(=O)OC)=CCC3N(CC)CC2 JWOSSISWAJNJIA-UHFFFAOYSA-N 0.000 description 1
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- ORZXYSPOAVJYRU-HOTGVXAUSA-N z-pro-prolinal Chemical compound O=C[C@@H]1CCCN1C(=O)[C@H]1N(C(=O)OCC=2C=CC=CC=2)CCC1 ORZXYSPOAVJYRU-HOTGVXAUSA-N 0.000 description 1
- BPKIMPVREBSLAJ-QTBYCLKRSA-N ziconotide Chemical compound C([C@H]1C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H]2C(=O)N[C@@H]3C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@H](C(N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CSSC2)C(N)=O)=O)CSSC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CSSC3)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(N1)=O)CCSC)[C@@H](C)O)C1=CC=C(O)C=C1 BPKIMPVREBSLAJ-QTBYCLKRSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Toxicology (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Urology & Nephrology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39926295A | 1995-03-06 | 1995-03-06 | |
| US08/603,102 US5872108A (en) | 1995-03-06 | 1996-02-20 | Reduction of infarct volume using citicoline |
| US08/609,448 US5827832A (en) | 1995-03-06 | 1996-03-01 | Method of protecting brain tissue from cerebral infarction subsequent to ischemia |
| PCT/US1996/003159 WO1996027380A1 (en) | 1995-03-06 | 1996-03-06 | Reduction of infarct volume using citicoline |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO974076D0 NO974076D0 (no) | 1997-09-04 |
| NO974076L NO974076L (no) | 1997-10-28 |
| NO313538B1 true NO313538B1 (no) | 2002-10-21 |
Family
ID=27410335
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19974076A NO313538B1 (no) | 1995-03-06 | 1997-09-04 | Anvendelse av citicolin samt farmasöytisk preparat |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP0813416B1 (zh) |
| JP (1) | JPH11511732A (zh) |
| CN (2) | CN1126546C (zh) |
| AT (1) | ATE296103T1 (zh) |
| AU (1) | AU5304796A (zh) |
| BR (1) | BR9607206A (zh) |
| CA (1) | CA2213000A1 (zh) |
| DE (1) | DE69634773T2 (zh) |
| ES (1) | ES2244968T3 (zh) |
| MX (1) | MX9706808A (zh) |
| NO (1) | NO313538B1 (zh) |
| PL (1) | PL185124B1 (zh) |
| PT (1) | PT813416E (zh) |
| WO (1) | WO1996027380A1 (zh) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5994392A (en) | 1988-02-26 | 1999-11-30 | Neuromedica, Inc. | Antipsychotic prodrugs comprising an antipsychotic agent coupled to an unsaturated fatty acid |
| CO4980891A1 (es) * | 1997-11-14 | 2000-11-27 | Sanofi Sa | Asociacion de principios activos para el tratamiento de la demencia senil de tipo azheimer |
| US5977174A (en) * | 1997-11-26 | 1999-11-02 | Neuromedica, Inc. | Cholinergic compositions and uses thereof |
| US6153653A (en) * | 1997-11-26 | 2000-11-28 | Protarga, Inc. | Choline compositions and uses thereof |
| US6197764B1 (en) | 1997-11-26 | 2001-03-06 | Protarga, Inc. | Clozapine compositions and uses thereof |
| JP4530534B2 (ja) * | 1997-12-24 | 2010-08-25 | フエルレル インターナショナル、ソシエダッド アノニマ | 超水和シチコリン、プロセスおよび使用 |
| US6225444B1 (en) | 1998-02-10 | 2001-05-01 | Protarga, Inc. | Neuroprotective peptides and uses thereof |
| ES2169986B1 (es) * | 2000-03-14 | 2003-06-16 | Ferrer Int | Uso de cdp-colina para el tratamiento profilactico de la isquemia cerebral. |
| WO2003039440A2 (en) | 2001-10-15 | 2003-05-15 | Janssen Pharmaceutica N.V. | Substituted 4-phenyl-4-(1h-imidazol-2-yl)-piperidine derivatives for reducing ischaemic damage |
| ES2345802B1 (es) * | 2009-03-30 | 2011-09-08 | Hospital Clinic I Provincial De Barcelona | Composicion farmaceutica para el tratamiento neuroprotector en pacientes con ictus. |
| JP6124417B2 (ja) | 2012-05-31 | 2017-05-10 | 学校法人近畿大学 | 抗癌剤に起因する末梢性神経障害性疼痛の予防及び／又は治療剤 |
| JP6166786B2 (ja) * | 2012-10-30 | 2017-07-19 | 協和発酵バイオ株式会社 | 脳機能低下の予防または改善剤 |
| CN105769882B (zh) * | 2016-03-14 | 2019-02-22 | 北京赛德维康医药研究院 | 一种抑制血栓形成的药物组合物及其用途 |
| WO2018206826A1 (es) | 2017-05-09 | 2018-11-15 | Hospital Clínic De Barcelona | Composición que comprende ácido úrico para el tratamiento de pacientes de infarto cerebral tratados con trombectomía mecánica |
| US11497795B2 (en) | 2018-09-28 | 2022-11-15 | Asahi Kasei Pharma Corporation | Medicament for mitigating conditions and/or suppressing onset of peripheral neuropathy induced by anti-malignant tumor agent |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4386078A (en) * | 1980-03-03 | 1983-05-31 | The Ohio State University Research Foundation | Therapeutic agents for preventing phospholipid degradation and free fatty acid proliferation |
| IT1207106B (it) * | 1980-04-18 | 1989-05-17 | Made Italiana Srl Ora Searle I | Preparazione farmaceutica contenente citidin disfofocolina assorbibile per via orale |
-
1996
- 1996-03-06 WO PCT/US1996/003159 patent/WO1996027380A1/en active IP Right Grant
- 1996-03-06 JP JP8527057A patent/JPH11511732A/ja active Pending
- 1996-03-06 EP EP96909616A patent/EP0813416B1/en not_active Expired - Lifetime
- 1996-03-06 AT AT96909616T patent/ATE296103T1/de not_active IP Right Cessation
- 1996-03-06 CN CN96193176A patent/CN1126546C/zh not_active Expired - Lifetime
- 1996-03-06 BR BR9607206A patent/BR9607206A/pt not_active Application Discontinuation
- 1996-03-06 ES ES96909616T patent/ES2244968T3/es not_active Expired - Lifetime
- 1996-03-06 PL PL96322061A patent/PL185124B1/pl unknown
- 1996-03-06 AU AU53047/96A patent/AU5304796A/en not_active Abandoned
- 1996-03-06 PT PT96909616T patent/PT813416E/pt unknown
- 1996-03-06 DE DE69634773T patent/DE69634773T2/de not_active Expired - Lifetime
- 1996-03-06 CA CA002213000A patent/CA2213000A1/en not_active Abandoned
- 1996-03-06 CN CNA021458014A patent/CN1488353A/zh active Pending
-
1997
- 1997-09-04 NO NO19974076A patent/NO313538B1/no not_active IP Right Cessation
- 1997-09-05 MX MX9706808A patent/MX9706808A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PL322061A1 (en) | 1998-01-05 |
| WO1996027380A1 (en) | 1996-09-12 |
| DE69634773T2 (de) | 2006-05-04 |
| CN1488353A (zh) | 2004-04-14 |
| CN1181015A (zh) | 1998-05-06 |
| MX9706808A (es) | 1998-08-30 |
| EP0813416A1 (en) | 1997-12-29 |
| CN1126546C (zh) | 2003-11-05 |
| JPH11511732A (ja) | 1999-10-12 |
| BR9607206A (pt) | 1997-11-11 |
| DE69634773D1 (de) | 2005-06-30 |
| NO974076L (no) | 1997-10-28 |
| CA2213000A1 (en) | 1996-09-12 |
| NO974076D0 (no) | 1997-09-04 |
| EP0813416B1 (en) | 2005-05-25 |
| AU5304796A (en) | 1996-09-23 |
| ES2244968T3 (es) | 2005-12-16 |
| EP0813416A4 (en) | 2000-11-15 |
| ATE296103T1 (de) | 2005-06-15 |
| PT813416E (pt) | 2005-10-31 |
| PL185124B1 (pl) | 2003-02-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK1K | Patent expired |