NO312958B1 - Akridinderivater, fremgangsmåte for fremstilling av disse og anvendelse av derivatene - Google Patents

Akridinderivater, fremgangsmåte for fremstilling av disse og anvendelse av derivatene Download PDF

Info

Publication number
NO312958B1
NO312958B1 NO19993320A NO993320A NO312958B1 NO 312958 B1 NO312958 B1 NO 312958B1 NO 19993320 A NO19993320 A NO 19993320A NO 993320 A NO993320 A NO 993320A NO 312958 B1 NO312958 B1 NO 312958B1
Authority
NO
Norway
Prior art keywords
hydrochloride
phenyl
acridin
dimethylaminomethyl
methoxy
Prior art date
Application number
NO19993320A
Other languages
English (en)
Norwegian (no)
Other versions
NO993320D0 (no
NO993320L (no
Inventor
Claudia Katharina Puetz
Wolfgang Werner A Strassburger
Oswald Zimmer
Werner Guenter Englberger
Original Assignee
Gruenenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh
Publication of NO993320D0 publication Critical patent/NO993320D0/no
Publication of NO993320L publication Critical patent/NO993320L/no
Publication of NO312958B1 publication Critical patent/NO312958B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D219/00Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D219/00Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C07D219/06Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D219/00Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/02Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with only hydrogen, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the ring system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D219/00Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C07D219/08Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Press Drives And Press Lines (AREA)
NO19993320A 1998-07-06 1999-07-05 Akridinderivater, fremgangsmåte for fremstilling av disse og anvendelse av derivatene NO312958B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19830105A DE19830105C1 (de) 1998-07-06 1998-07-06 Acridinderivate

Publications (3)

Publication Number Publication Date
NO993320D0 NO993320D0 (no) 1999-07-05
NO993320L NO993320L (no) 2000-01-07
NO312958B1 true NO312958B1 (no) 2002-07-22

Family

ID=7873106

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19993320A NO312958B1 (no) 1998-07-06 1999-07-05 Akridinderivater, fremgangsmåte for fremstilling av disse og anvendelse av derivatene

Country Status (29)

Country Link
US (2) US6077845A (ko)
EP (2) EP1369417A1 (ko)
JP (1) JP2000026426A (ko)
KR (1) KR100601742B1 (ko)
CN (1) CN1206221C (ko)
AR (1) AR019219A1 (ko)
AT (1) ATE247643T1 (ko)
AU (1) AU749935B2 (ko)
BR (1) BR9903115A (ko)
CA (1) CA2276764C (ko)
CO (1) CO5080790A1 (ko)
CZ (1) CZ296559B6 (ko)
DE (2) DE19830105C1 (ko)
DK (1) DK0970949T3 (ko)
ES (1) ES2205642T3 (ko)
HK (1) HK1024699A1 (ko)
HU (1) HU226039B1 (ko)
IL (1) IL130801A (ko)
MY (1) MY124404A (ko)
NO (1) NO312958B1 (ko)
NZ (1) NZ336122A (ko)
PE (1) PE20000733A1 (ko)
PL (1) PL193386B1 (ko)
PT (1) PT970949E (ko)
RU (1) RU2225399C2 (ko)
SI (1) SI0970949T1 (ko)
SK (1) SK284234B6 (ko)
UY (1) UY25592A1 (ko)
ZA (1) ZA994369B (ko)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10000311A1 (de) * 2000-01-05 2001-07-12 Gruenenthal Gmbh Aminomethyl-Phonyl-Cyclohexanonderivate
KR100381716B1 (ko) * 2000-10-09 2003-04-26 한국화학연구원 항암활성을 가지는 아크리딘 유도체
HUE026184T2 (en) * 2008-03-27 2016-05-30 Gruenenthal Gmbh (Hetero-) aryl-cyclohexane derivatives
CN105315205B (zh) * 2015-01-19 2018-03-23 威海惠安康生物科技有限公司 一种以邻硝基苯甲醛和环己醇为原料制备吖啶的方法
RU2616247C1 (ru) * 2016-03-28 2017-04-13 Федеральное государственное бюджетное образовательное учреждение высшего образования "Северо-Осетинский государственный университет имени Коста Левановича Хетагурова" (СОГУ) Твердая лекарственная форма, обладающая холинопозитивным действием, на основе 9-бутиламино-3,3-диметил-1,2,4-тригидроакридина

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3652589A (en) * 1967-07-27 1972-03-28 Gruenenthal Chemie 1-(m-substituted phenyl)-2-aminomethyl cyclohexanols
US4851536A (en) * 1987-05-07 1989-07-25 American Home Products Corporation Cyclohexylquinolines as inhibitors of interleukin 1
DE19525137C2 (de) * 1995-07-11 2003-02-27 Gruenenthal Gmbh 6-Dimethylaminomethyl-1-phenyl-cyclohexanverbin -dungen als Zwischenprodukte zur Herstellung pharmazeutischer Wirkstoffe
DE19547766A1 (de) * 1995-12-20 1997-06-26 Gruenenthal Gmbh 1-Phenyl-2-dimethylaminomethyl-cyclohexan-1-ol-verbindungen als pharmazeutische Wirkstoffe
DE19609847A1 (de) * 1996-03-13 1997-09-18 Gruenenthal Gmbh Dimethyl-(3-aryl-but-3-enyl)-aminverbindungen als pharmazeutische Wirkstoffe
DE19805370A1 (de) * 1997-03-14 1998-09-17 Gruenenthal Gmbh Substituierte Aminoverbindungen und ihre Verwendung als analgetisch wirksame Substanzen
DE19755480A1 (de) * 1997-12-13 1999-06-24 Gruenenthal Gmbh Substituierte heterocyclische Benzocycloalkene und ihre Verwendung als analgetisch wirksame Substanzen

Also Published As

Publication number Publication date
IL130801A0 (en) 2001-01-28
CN1206221C (zh) 2005-06-15
NO993320D0 (no) 1999-07-05
NZ336122A (en) 2001-02-23
ES2205642T3 (es) 2004-05-01
AU3798399A (en) 2000-01-20
JP2000026426A (ja) 2000-01-25
KR100601742B1 (ko) 2006-07-19
PE20000733A1 (es) 2000-08-12
CO5080790A1 (es) 2001-09-25
HK1024699A1 (en) 2000-10-20
CA2276764C (en) 2009-08-18
US6274768B1 (en) 2001-08-14
HU9902270D0 (en) 1999-09-28
SK284234B6 (en) 2004-11-03
BR9903115A (pt) 2000-06-20
CN1240788A (zh) 2000-01-12
DE59906645D1 (de) 2003-09-25
SI0970949T1 (en) 2003-12-31
EP1369417A1 (de) 2003-12-10
ZA994369B (en) 2000-01-11
HUP9902270A1 (hu) 2000-06-28
NO993320L (no) 2000-01-07
RU2225399C2 (ru) 2004-03-10
CA2276764A1 (en) 2000-01-06
EP0970949A1 (de) 2000-01-12
DE19830105C1 (de) 2000-02-17
MY124404A (en) 2006-06-30
KR20000011483A (ko) 2000-02-25
CZ296559B6 (cs) 2006-04-12
CZ240799A3 (cs) 2000-01-12
SK90899A3 (en) 2000-03-13
EP0970949B1 (de) 2003-08-20
HU226039B1 (en) 2008-03-28
UY25592A1 (es) 2001-05-31
US6077845A (en) 2000-06-20
PT970949E (pt) 2003-12-31
DK0970949T3 (da) 2003-11-24
AU749935B2 (en) 2002-07-04
AR019219A1 (es) 2001-12-26
PL193386B1 (pl) 2007-02-28
ATE247643T1 (de) 2003-09-15
IL130801A (en) 2006-06-11

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