NO308842B1 - Nye retinoider, anvendelse derav, og farmasøytiske preparater inneholdende dem - Google Patents

Nye retinoider, anvendelse derav, og farmasøytiske preparater inneholdende dem

Info

Publication number
NO308842B1
NO308842B1 NO971711A NO971711A NO308842B1 NO 308842 B1 NO308842 B1 NO 308842B1 NO 971711 A NO971711 A NO 971711A NO 971711 A NO971711 A NO 971711A NO 308842 B1 NO308842 B1 NO 308842B1
Authority
NO
Norway
Prior art keywords
pharmaceutical compositions
compositions containing
new retinoids
retinoids
new
Prior art date
Application number
NO971711A
Other languages
English (en)
Norwegian (no)
Other versions
NO971711L (no
NO971711D0 (no
Inventor
Michael Klaus
Peter Mohr
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO971711D0 publication Critical patent/NO971711D0/no
Publication of NO971711L publication Critical patent/NO971711L/no
Publication of NO308842B1 publication Critical patent/NO308842B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/20—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by carboxyl groups or halides, anhydrides, or (thio)esters thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/62—Unsaturated compounds containing ether groups, groups, groups, or groups containing rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/732—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids of unsaturated hydroxy carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/09—Geometrical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Nutrition Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO971711A 1996-04-15 1997-04-14 Nye retinoider, anvendelse derav, og farmasøytiske preparater inneholdende dem NO308842B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP96105849 1996-04-15

Publications (3)

Publication Number Publication Date
NO971711D0 NO971711D0 (no) 1997-04-14
NO971711L NO971711L (no) 1997-10-16
NO308842B1 true NO308842B1 (no) 2000-11-06

Family

ID=8222666

Family Applications (1)

Application Number Title Priority Date Filing Date
NO971711A NO308842B1 (no) 1996-04-15 1997-04-14 Nye retinoider, anvendelse derav, og farmasøytiske preparater inneholdende dem

Country Status (29)

Country Link
US (1) US5990329A (zh)
JP (1) JP2801589B2 (zh)
KR (1) KR100240542B1 (zh)
CN (1) CN1116270C (zh)
AR (1) AR006632A1 (zh)
AT (1) ATE187962T1 (zh)
AU (1) AU715816B2 (zh)
BR (1) BR9701790A (zh)
CA (1) CA2202228C (zh)
CO (1) CO4890844A1 (zh)
CZ (1) CZ113397A3 (zh)
DE (1) DE59700872D1 (zh)
DK (1) DK0802181T3 (zh)
ES (1) ES2141556T3 (zh)
HK (1) HK1003054A1 (zh)
HR (1) HRP970204B1 (zh)
HU (1) HU220112B (zh)
IL (1) IL120637A (zh)
MA (1) MA24142A1 (zh)
NO (1) NO308842B1 (zh)
NZ (1) NZ314525A (zh)
PE (1) PE42498A1 (zh)
PL (1) PL319477A1 (zh)
PT (1) PT802181E (zh)
SG (1) SG52949A1 (zh)
TR (1) TR199700297A2 (zh)
TW (1) TW442459B (zh)
YU (1) YU14997A (zh)
ZA (1) ZA972944B (zh)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2344653A1 (en) 1998-09-29 2000-04-06 Gamida Cell Ltd. Methods of controlling proliferation and differentiation of stem and progenitor cells
IL152904A0 (en) 2002-01-24 2003-06-24 Gamida Cell Ltd Utilization of retinoid and vitamin d receptor antagonists for expansion of renewable stem cell populations
WO2003062404A1 (en) 2002-01-25 2003-07-31 Gamida-Cell Ltd. Methods of expanding stem and progenitor cells and expanded cell populations obtained thereby
WO2006030442A2 (en) 2004-09-16 2006-03-23 Gamida-Cell Ltd. Methods of ex vivo progenitor and stem cell expansion by co-culture with mesenchymal cells
US8846393B2 (en) 2005-11-29 2014-09-30 Gamida-Cell Ltd. Methods of improving stem cell homing and engraftment
US20150064273A1 (en) 2012-02-13 2015-03-05 Gamida-Cell Ltd. Mesenchymal Stem Cells Conditioned Medium and Methods of Generating and Using the Same
US9175266B2 (en) 2012-07-23 2015-11-03 Gamida Cell Ltd. Enhancement of natural killer (NK) cell proliferation and activity
US9567569B2 (en) 2012-07-23 2017-02-14 Gamida Cell Ltd. Methods of culturing and expanding mesenchymal stem cells

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4169103A (en) * 1978-04-12 1979-09-25 Hoffmann-La Roche Inc. Nonatetraenoic acid derivatives
DE2843901A1 (de) * 1978-10-07 1980-04-24 Basf Ag Mittel, enthaltend all-e- oder 13-z-7, 8-dehydro-retinsaeure
CH658387A5 (de) * 1984-04-02 1986-11-14 Hoffmann La Roche Pharmazeutische praeparate.
CZ282548B6 (cs) * 1992-01-22 1997-08-13 F. Hoffmann-La Roche Ag Farmaceutický přípravek

Also Published As

Publication number Publication date
DE59700872D1 (de) 2000-01-27
HRP970204A2 (en) 1998-04-30
PT802181E (pt) 2000-05-31
ATE187962T1 (de) 2000-01-15
JP2801589B2 (ja) 1998-09-21
AU715816B2 (en) 2000-02-10
HRP970204B1 (en) 2000-10-31
HU9700747D0 (en) 1997-05-28
NO971711L (no) 1997-10-16
CN1116270C (zh) 2003-07-30
ES2141556T3 (es) 2000-03-16
JPH1036343A (ja) 1998-02-10
IL120637A (en) 2000-11-21
BR9701790A (pt) 1998-11-10
YU14997A (sh) 1999-09-27
MX9702697A (es) 1997-10-31
MA24142A1 (fr) 1997-12-31
HU220112B (hu) 2001-11-28
CO4890844A1 (es) 2000-02-28
AR006632A1 (es) 1999-09-08
SG52949A1 (en) 1998-09-28
CA2202228C (en) 2007-03-06
KR100240542B1 (ko) 2000-01-15
NZ314525A (en) 1998-02-26
HUP9700747A1 (en) 1997-12-29
US5990329A (en) 1999-11-23
CA2202228A1 (en) 1997-10-15
TR199700297A2 (xx) 1997-11-21
CN1167752A (zh) 1997-12-17
KR970069969A (ko) 1997-11-07
HUP9700747A3 (en) 1998-04-28
NO971711D0 (no) 1997-04-14
PE42498A1 (es) 1998-08-18
PL319477A1 (en) 1997-10-27
AU1772697A (en) 1997-10-23
IL120637A0 (en) 1997-08-14
CZ113397A3 (cs) 1998-02-18
TW442459B (en) 2001-06-23
HK1003054A1 (en) 1998-10-09
DK0802181T3 (da) 2000-04-17
ZA972944B (en) 1997-10-15

Similar Documents

Publication Publication Date Title
IL138028A0 (en) Metalloproteinase inhibitors, pharmaceutical compositions containing them and their pharmaceutical use
NO308298B1 (no) Substituerte kinazolinderivater, anvendelse derav og farmasøytiske preparater inneholdende dem
NO973922L (no) Nye taxoider, deres fremstilling og farmasöytiske preparater inneholdende forbindelsene
NO955034D0 (no) Nye substituerte 1H-imidazoler og farmasöytiske preparater inneholdende disse
DK0835246T3 (da) Aromatiske forbindelser og farmaceutiske præparater, der indeholder dem
NO983635D0 (no) Dentalforbindelser, sammensetninger og produkter
NO307707B1 (no) Spiroazabicykliske forbindelser, farmasøytisk preparat inneholdende slike forbindelser og anvendelse derav
NO307925B1 (no) Bicykliske aromatiske forbindelser, anvendelse derav, og farmasøytiske og kosmetiske preparater
DK1112266T3 (da) Substituerede 4-amino-2-arylpyrimidiner, fremstilling og anvendelse deraf og farmaceutiske præparater indeholdende dem
DK0876362T3 (da) Nye taxoider, deres fremstilling og farmaceutiske præparater deraf
NO942835D0 (no) 1-benzensulfonyl-1,3-dihydro-2H-benzimidazol-2-on-derivater, fremstilling derav og farmasöytiske blandinger som inneholder dem
NO976128D0 (no) Forbindelser og farmasöytiske blandinger som inneholder dem
NO975984D0 (no) Aromatiske forbindelser og farmasöytiske blandinger inneholdende dem
NO307092B1 (no) Sordaridin-derivater, anvendelse derav og farmasoeytisk blanding
HUP9904694A3 (en) Spiropyrrolidine derivatives, their use and pharmaceutical compositions containing them
HUP9904682A3 (en) Phenyloxazole and -thiazole derivatives, their use and pharmaceutical compositions containing them
DK0776881T3 (da) Diaromatiske forbindelser, der bærer en adamantylgruppe i parastilling, farmaceutiske og kosmetiske præparater, der indehol
DK0732328T3 (da) Heterocykliske, aromatiske forbindelser, farmaceutiske og kosmetiske sammensætninger, der indeholder dem, og anvendelser
DK0820448T3 (da) Nye taxoider, deres fremstilling og farmaceutiske præparater deraf
HUP9900071A3 (en) Tribenzimidazoles useful as topoisomerase i inhibitors, pharmaceutical compositions containing them and their use
IS4809A (is) Taxóíð, efnasmíði þeirra og lyfjasamsetning sem inniheldur þau
NO983678D0 (no) Nye cefemforbindelser og farmasöytiske anvendelser derav
NO308842B1 (no) Nye retinoider, anvendelse derav, og farmasøytiske preparater inneholdende dem
NO984444D0 (no) Benzothiofener, formuleringer som inneholder de samme, og fremgangsmÕter
NO995838D0 (no) Nye heteroetynylenforbindelser og farmasöytiske og kosmetiske preparater inneholdende de samme

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees

Free format text: LAPSED IN OCTOBER 2002