NO307828B1 - FremgangsmÕte for fremstilling av Astaxantin og nye mellomprodukter derav - Google Patents
FremgangsmÕte for fremstilling av Astaxantin og nye mellomprodukter deravInfo
- Publication number
- NO307828B1 NO307828B1 NO942523A NO942523A NO307828B1 NO 307828 B1 NO307828 B1 NO 307828B1 NO 942523 A NO942523 A NO 942523A NO 942523 A NO942523 A NO 942523A NO 307828 B1 NO307828 B1 NO 307828B1
- Authority
- NO
- Norway
- Prior art keywords
- astaxanthin
- preparation
- new intermediates
- intermediates
- new
- Prior art date
Links
- JEBFVOLFMLUKLF-IFPLVEIFSA-N Astaxanthin Natural products CC(=C/C=C/C(=C/C=C/C1=C(C)C(=O)C(O)CC1(C)C)/C)C=CC=C(/C)C=CC=C(/C)C=CC2=C(C)C(=O)C(O)CC2(C)C JEBFVOLFMLUKLF-IFPLVEIFSA-N 0.000 title 1
- MQZIGYBFDRPAKN-ZWAPEEGVSA-N astaxanthin Chemical compound C([C@H](O)C(=O)C=1C)C(C)(C)C=1/C=C/C(/C)=C/C=C/C(/C)=C/C=C/C=C(C)C=CC=C(C)C=CC1=C(C)C(=O)[C@@H](O)CC1(C)C MQZIGYBFDRPAKN-ZWAPEEGVSA-N 0.000 title 1
- 229940022405 astaxanthin Drugs 0.000 title 1
- 235000013793 astaxanthin Nutrition 0.000 title 1
- 239000001168 astaxanthin Substances 0.000 title 1
- 239000000543 intermediate Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
- C07C403/24—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by six-membered non-aromatic rings, e.g. beta-carotene
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
- C07C403/04—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
- C07C403/06—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms
- C07C403/08—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms by hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
- C07C403/06—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms
- C07C403/10—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms by etherified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/54—Quaternary phosphonium compounds
- C07F9/5435—Cycloaliphatic phosphonium compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/54—Quaternary phosphonium compounds
- C07F9/5442—Aromatic phosphonium compounds (P-C aromatic linkage)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4322277A DE4322277A1 (de) | 1993-07-05 | 1993-07-05 | Verbessertes Verfahren zur Herstellung von Astaxanthin, neue Zwischenprodukte hierfür sowie ein Verfahren zu deren Herstellung |
Publications (3)
Publication Number | Publication Date |
---|---|
NO942523D0 NO942523D0 (no) | 1994-07-04 |
NO942523L NO942523L (no) | 1995-01-06 |
NO307828B1 true NO307828B1 (no) | 2000-06-05 |
Family
ID=6491956
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO942523A NO307828B1 (no) | 1993-07-05 | 1994-07-04 | FremgangsmÕte for fremstilling av Astaxantin og nye mellomprodukter derav |
Country Status (7)
Country | Link |
---|---|
US (2) | US5455362A (no) |
EP (1) | EP0633258B1 (no) |
JP (2) | JP3679430B2 (no) |
CN (1) | CN1052001C (no) |
CA (1) | CA2127047C (no) |
DE (2) | DE4322277A1 (no) |
NO (1) | NO307828B1 (no) |
Families Citing this family (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19509955A1 (de) * | 1995-03-18 | 1996-09-19 | Basf Ag | Verfahren zur Herstellung von Astaxanthin |
US6376717B2 (en) * | 2000-04-26 | 2002-04-23 | Prodemex, S.A. De C.V. | Preparation of astaxanthin |
DE10049271A1 (de) * | 2000-09-28 | 2002-04-11 | Basf Ag | Verfahren zur katalytischen Reduktion von Alkinverbindungen |
DE10140180A1 (de) | 2001-08-22 | 2003-03-06 | Basf Ag | Verfahren zur selektiven Reduktion von Alkinverbindungen |
EP1423350A1 (de) * | 2001-08-29 | 2004-06-02 | Basf Aktiengesellschaft | Verfahren zur herstellung von oxo-cyclohexyl- oder oxo-cyclohexylenderivaten |
US6372946B1 (en) * | 2001-09-13 | 2002-04-16 | Prodemex, S.A. De C.V. | Preparation of 4,4′-diketo-β-carotene derivatives |
MX247604B (es) * | 2002-02-06 | 2007-07-30 | Dsm Ip Assets Bv | Esteres de astaxantina. |
US20050059659A1 (en) * | 2002-07-29 | 2005-03-17 | Lockwood Samuel Fournier | Carotenoid analogs or derivatives for controlling C-reactive protein levels |
US7345091B2 (en) * | 2002-07-29 | 2008-03-18 | Cardax Pharmaceuticals, Inc. | Carotenoid ether analogs or derivatives for the inhibition and amelioration of disease |
US7375133B2 (en) | 2002-07-29 | 2008-05-20 | Cardax Pharmaceuticals, Inc. | Pharmaceutical compositions including carotenoid ether analogs or derivatives for the inhibition and amelioration of disease |
US7521584B2 (en) * | 2002-07-29 | 2009-04-21 | Cardax Pharmaceuticals, Inc. | Carotenoid analogs or derivatives for the inhibition and amelioration of disease |
US20050049248A1 (en) * | 2002-07-29 | 2005-03-03 | Lockwood Samuel Fournier | Carotenoid ether analogs or derivatives for controlling C-reactive protein levels |
US7145025B2 (en) * | 2002-07-29 | 2006-12-05 | Hawaii Biotech, Inc. | Structural carotenoid analogs for the inhibition and amelioration of disease |
US7763649B2 (en) * | 2002-07-29 | 2010-07-27 | Cardax Pharmaceuticals, Inc. | Carotenoid analogs or derivatives for controlling connexin 43 expression |
US20050026874A1 (en) * | 2002-07-29 | 2005-02-03 | Lockwood Samuel Fournier | Carotenoid ether analogs or derivatives for the inhibition and amelioration of liver disease |
US20050059635A1 (en) * | 2002-07-29 | 2005-03-17 | Lockwood Samuel Fournier | Carotenoid ester analogs or derivatives for controlling C-reactive protein levels |
US20050148517A1 (en) * | 2002-07-29 | 2005-07-07 | Lockwood Samuel F. | Carotenoid ether analogs or derivatives for controlling connexin 43 expression |
US7320997B2 (en) * | 2002-07-29 | 2008-01-22 | Cardax Pharmaceuticals, Inc. | Pharmaceutical compositions including carotenoid ester analogs or derivatives for the inhibition and amelioration of disease |
US20050143475A1 (en) * | 2002-07-29 | 2005-06-30 | Lockwood Samuel F. | Carotenoid analogs or derivatives for the inhibition and amelioration of ischemic reperfusion injury |
US7723327B2 (en) * | 2002-07-29 | 2010-05-25 | Cardax Pharmaceuticals, Inc. | Carotenoid ester analogs or derivatives for the inhibition and amelioration of liver disease |
US20050009788A1 (en) * | 2002-07-29 | 2005-01-13 | Lockwood Samuel Fournier | Carotenoid ester analogs or derivatives for controlling connexin 43 expression |
US20050004235A1 (en) * | 2002-07-29 | 2005-01-06 | Lockwood Samuel Fournier | Carotenoid analogs or derivatives for the inhibition and amelioration of liver disease |
DE10254809A1 (de) * | 2002-11-22 | 2004-06-03 | Basf Ag | Verfahren zur Herstellung von Carotinoiden |
DE10358003A1 (de) * | 2003-12-11 | 2005-07-14 | Basf Ag | Verfahren zur Herstellung von Astaxanthin- und Canthaxanthin-Vorprodukten |
US20060058269A1 (en) * | 2004-04-14 | 2006-03-16 | Lockwood Samuel F | Carotenoid analogs or derivatives for the inhibition and amelioration of inflammation |
EP1750723A1 (en) * | 2004-04-14 | 2007-02-14 | Hawaii Biotech, Inc. | Carotenoid analogs or derivatives for the inhibition and amelioration of inflammation |
US20060167319A1 (en) * | 2004-10-01 | 2006-07-27 | Lockwood Samuel F | Methods for the synthesis of unsaturated ketone intermediates useful for the synthesis of carotenoids |
US20060078889A1 (en) * | 2004-10-08 | 2006-04-13 | Arindam Bhattacharjee | Array-based methods for producing ribonucleic acids |
US20070099195A1 (en) * | 2005-11-02 | 2007-05-03 | Huang Xiaohua C | Methods and compositions for separating nucleic acids from a solid support |
CN101148434B (zh) * | 2006-09-20 | 2010-07-28 | 浙江医药股份有限公司新昌制药厂 | 十五碳三苯基膦盐的合成方法 |
CN101148433B (zh) * | 2006-09-20 | 2011-01-12 | 浙江医药股份有限公司新昌制药厂 | 十五碳醇的合成方法 |
CL2008001699A1 (es) | 2008-06-09 | 2010-02-05 | Univ Chile | Secuencia de adn que codifica enzima con actividad citocromo p450 reductasa de x. dendrorhous; secuencia de polipeptido codificada; vector o plasmido; celula hesped; proceso de produccion de polipeptido; proceso de produccion de astaxantina desde beta-caroteno; composiciones, productos y/o formulaciones. |
TWI501946B (zh) * | 2010-02-08 | 2015-10-01 | Basf Se | 蝦紅素二琥珀酸二甲酯之製造方法 |
CN102002033B (zh) * | 2010-12-23 | 2013-11-20 | 厦门金达威集团股份有限公司 | 一种虾青素中间体的保护方法 |
CN103087039B (zh) * | 2013-01-22 | 2014-08-13 | 河南师范大学 | 一种多取代苯并[1,3]间二氧杂环戊烷类化合物的合成方法 |
EP3065568B1 (en) * | 2013-11-07 | 2019-12-25 | DSM IP Assets B.V. | Process for the purification of astaxanthin |
EP3065567B1 (en) * | 2013-11-07 | 2019-12-25 | DSM IP Assets B.V. | Process for the purification of astaxanthin |
WO2015067709A1 (en) * | 2013-11-07 | 2015-05-14 | Dsm Ip Assets B.V. | Process for the purification of astaxanthin |
CN109965279A (zh) * | 2013-11-07 | 2019-07-05 | 帝斯曼知识产权资产管理有限公司 | 包含合成的食品级虾青素的粉状制剂、油质悬浮物和膳食补充剂 |
EP3065566B1 (en) * | 2013-11-07 | 2019-10-02 | DSM IP Assets B.V. | Process for the purification of astaxanthin |
WO2015067707A1 (en) * | 2013-11-07 | 2015-05-14 | Dsm Ip Assets B.V. | Process for the purification of astaxanthin |
WO2016023772A1 (de) * | 2014-08-12 | 2016-02-18 | Basf Se | Verfahren zur herstellung zyklischer alpha-ketoalkohole aus zyklischen alpha-ketoenolen |
EP3180311B1 (de) | 2014-08-12 | 2019-04-17 | Basf Se | Verfahren zur herstellung von astaxanthin aus astacin |
CN106316908B (zh) * | 2015-06-30 | 2018-02-13 | 上虞新和成生物化工有限公司 | 一种高纯度虾青素的合成方法 |
CN110088094A (zh) * | 2016-12-19 | 2019-08-02 | 巴斯夫欧洲公司 | 制备立体异构纯c9-缩醛的方法 |
CN107739390B (zh) * | 2017-09-29 | 2019-08-20 | 上虞新和成生物化工有限公司 | 一种虾青素中间体的合成方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2964401D1 (en) * | 1978-06-02 | 1983-02-03 | Hoffmann La Roche | Process for the preparation of cyclohexenyl derivatives, and intermediates produced in the synthesis |
DE2965093D1 (en) * | 1978-06-02 | 1983-05-05 | Hoffmann La Roche | Derivatives of cyclohexene, process for their peparation, as well as their uses |
DE3377127D1 (en) * | 1982-08-20 | 1988-07-28 | Hoffmann La Roche | Process for the preparation of astaxanthine and intermediates in the astaxanthine synthesis |
DE4014203A1 (de) * | 1990-05-03 | 1991-11-07 | Basf Ag | Verfahren zur herstellung von canthaxanthin und astaxanthin |
-
1993
- 1993-07-05 DE DE4322277A patent/DE4322277A1/de not_active Withdrawn
-
1994
- 1994-06-27 DE DE59408898T patent/DE59408898D1/de not_active Expired - Lifetime
- 1994-06-27 EP EP94109921A patent/EP0633258B1/de not_active Expired - Lifetime
- 1994-06-27 US US08/265,741 patent/US5455362A/en not_active Expired - Lifetime
- 1994-06-29 CA CA002127047A patent/CA2127047C/en not_active Expired - Fee Related
- 1994-07-04 NO NO942523A patent/NO307828B1/no not_active IP Right Cessation
- 1994-07-04 JP JP15244394A patent/JP3679430B2/ja not_active Expired - Fee Related
- 1994-07-05 CN CN94108274A patent/CN1052001C/zh not_active Expired - Lifetime
-
1995
- 1995-05-23 US US08/471,314 patent/US5625099A/en not_active Expired - Lifetime
-
2004
- 2004-07-08 JP JP2004202237A patent/JP2004292461A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
CN1098101A (zh) | 1995-02-01 |
CA2127047A1 (en) | 1995-01-06 |
EP0633258A1 (de) | 1995-01-11 |
NO942523D0 (no) | 1994-07-04 |
NO942523L (no) | 1995-01-06 |
DE4322277A1 (de) | 1995-01-12 |
CN1052001C (zh) | 2000-05-03 |
DE59408898D1 (de) | 1999-12-16 |
CA2127047C (en) | 2005-09-20 |
EP0633258B1 (de) | 1999-11-10 |
US5455362A (en) | 1995-10-03 |
JPH0753508A (ja) | 1995-02-28 |
US5625099A (en) | 1997-04-29 |
JP2004292461A (ja) | 2004-10-21 |
JP3679430B2 (ja) | 2005-08-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MK1K | Patent expired |