FI960254A0 - Menetelmä N-(4-hydroksifenyyli)-retiiniamidin valmistamiseksi - Google Patents

Menetelmä N-(4-hydroksifenyyli)-retiiniamidin valmistamiseksi

Info

Publication number
FI960254A0
FI960254A0 FI960254A FI960254A FI960254A0 FI 960254 A0 FI960254 A0 FI 960254A0 FI 960254 A FI960254 A FI 960254A FI 960254 A FI960254 A FI 960254A FI 960254 A0 FI960254 A0 FI 960254A0
Authority
FI
Finland
Prior art keywords
retinamide
hydroxyphenyl
preparation
Prior art date
Application number
FI960254A
Other languages
English (en)
Swedish (sv)
Other versions
FI960254A (fi
Inventor
Cynthia A Maryanoff
Original Assignee
Ortho Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Pharma Corp filed Critical Ortho Pharma Corp
Publication of FI960254A0 publication Critical patent/FI960254A0/fi
Publication of FI960254A publication Critical patent/FI960254A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/20—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by carboxyl groups or halides, anhydrides, or (thio)esters thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FI960254A 1993-07-20 1996-01-18 Menetelmä N-(4-hydroksifenyyli)-retiiniamidin valmistamiseksi FI960254A (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/095,075 US5399757A (en) 1993-07-20 1993-07-20 Process for the preparation of N-(4-hydroxyphenyl)-retinamide
PCT/US1994/005772 WO1995003274A1 (en) 1993-07-20 1994-05-18 Process for the preparation of n-(4-hydroxyphenyl)-retinamide

Publications (2)

Publication Number Publication Date
FI960254A0 true FI960254A0 (fi) 1996-01-18
FI960254A FI960254A (fi) 1996-03-19

Family

ID=22249315

Family Applications (1)

Application Number Title Priority Date Filing Date
FI960254A FI960254A (fi) 1993-07-20 1996-01-18 Menetelmä N-(4-hydroksifenyyli)-retiiniamidin valmistamiseksi

Country Status (13)

Country Link
US (1) US5399757A (fi)
EP (1) EP0711276A1 (fi)
JP (1) JPH09500641A (fi)
CN (1) CN1130376A (fi)
AU (1) AU682878B2 (fi)
BR (1) BR9407090A (fi)
CA (1) CA2167582A1 (fi)
CZ (1) CZ13996A3 (fi)
FI (1) FI960254A (fi)
HU (1) HUT73014A (fi)
PL (1) PL312663A1 (fi)
WO (1) WO1995003274A1 (fi)
ZA (1) ZA945261B (fi)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1068181B1 (en) * 1998-03-30 2003-05-07 Lg Chemical Limited Polyethoxylated retinamide derivatives and process for preparing the same
ATE260242T1 (de) 1998-12-17 2004-03-15 Hoffmann La Roche 7-aryl-6(z)heptatriensäure retinamide als apoptose induzierende verbindungen und deren verwendung als antikrebsmittel
KR100392339B1 (ko) * 2000-12-27 2003-07-23 김향자 동물 케이지용 깔짚 및 그 성형장치와 방법
US6696606B2 (en) * 2001-07-06 2004-02-24 The Ohio State University Research Foundation Solid phase synthesis of arylretinamides
EP1692521A1 (en) * 2003-12-11 2006-08-23 Beth Israel Deaconess Medical Center, Inc. Rbp4 in insulin sensitivity/resistance, diabetes, and obesity
EP1768657B1 (en) 2004-06-23 2008-08-13 Sirion Therapeutics, Inc. Methods and compositions for treating ophthalmic conditions with retinyl derivates
EP1804788A4 (en) * 2004-10-25 2008-05-21 Sirion Therapeutics Inc DETECTION AND ANALYSIS OF FLUORESCENT MOLECULES RELATING TO OPHTHALMOLOGY
KR20070091283A (ko) * 2004-11-04 2007-09-10 시리온 테라퓨틱스, 인크. 레티놀-레티놀 결합단백질(ｒｂｐ)-트랜스타이레틴(ｔｔｒ) 복합체 형성의조절 인자
UA81382C2 (en) * 2005-07-11 2007-12-25 Composition for treating retinol-related diseases by modulation of retinol binding
US7321064B1 (en) 2007-03-08 2008-01-22 Cedarburg Pharmaceuticals, Inc. Preparation of amides of retinoic acid via mixed anhydride and mixed carbonate intermediates
EP2263456A1 (de) 2009-06-18 2010-12-22 LANXESS Deutschland GmbH Amidoalkylaminhaltige Azol-Zusammensetzungen für den Schutz technischer Materialien
CN102260186B (zh) * 2011-05-09 2014-03-12 北京吉科特科技有限责任公司 4-羧基苯基视黄酰胺基乙醇合物及其制备方法和药物组合物
ES2686733T3 (es) * 2014-09-17 2018-10-19 Fondazione Irccs Istituto Nazionale Dei Tumori Derivados de 4-oxo-N-(4-hidroxifenil)retinamida como agentes terapéuticos para el tratamiento de cáncer
CN114436924B (zh) * 2022-02-21 2023-09-29 青岛三人行化学有限公司 一种羟基频哪酮视黄酸酯的合成方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4190594A (en) * 1975-11-03 1980-02-26 Johnson & Johnson Retinoic acid derivatives
US4323581A (en) * 1978-07-31 1982-04-06 Johnson & Johnson Method of treating carcinogenesis
EP0063538B1 (de) * 1981-04-13 1986-08-06 Schering Aktiengesellschaft Neue Prostaglandine und Prostacycline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
US4743400A (en) * 1986-09-22 1988-05-10 Mcneilab, Inc. Process for preparing retinoyl chlorides

Also Published As

Publication number Publication date
HU9600121D0 (en) 1996-03-28
PL312663A1 (en) 1996-04-29
HUT73014A (en) 1996-06-28
CN1130376A (zh) 1996-09-04
ZA945261B (en) 1996-01-19
US5399757A (en) 1995-03-21
CA2167582A1 (en) 1995-02-02
WO1995003274A1 (en) 1995-02-02
BR9407090A (pt) 1996-09-10
EP0711276A1 (en) 1996-05-15
AU682878B2 (en) 1997-10-23
CZ13996A3 (en) 1996-06-12
AU6955794A (en) 1995-02-20
JPH09500641A (ja) 1997-01-21
FI960254A (fi) 1996-03-19

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Legal Events

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