NO307570B1 - Inklusjonskomplekser oppnådd fra nimesulidalkali- og nimesulidjordalkalisalter og cyklodekstriner eller cyklodekstrinderivater, samt farmasøytisk preparat inneholdende nevnte inklusjonskompleks og fremgangsmåte for å fremstille samme - Google Patents
Inklusjonskomplekser oppnådd fra nimesulidalkali- og nimesulidjordalkalisalter og cyklodekstriner eller cyklodekstrinderivater, samt farmasøytisk preparat inneholdende nevnte inklusjonskompleks og fremgangsmåte for å fremstille sammeInfo
- Publication number
- NO307570B1 NO307570B1 NO950243A NO950243A NO307570B1 NO 307570 B1 NO307570 B1 NO 307570B1 NO 950243 A NO950243 A NO 950243A NO 950243 A NO950243 A NO 950243A NO 307570 B1 NO307570 B1 NO 307570B1
- Authority
- NO
- Norway
- Prior art keywords
- nimesulide
- cyclodextrins
- alkaline earth
- well
- inclusion
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
- A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
- C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
- C08B37/0015—Inclusion compounds, i.e. host-guest compounds, e.g. polyrotaxanes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Nanotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Biophysics (AREA)
- Materials Engineering (AREA)
- Polymers & Plastics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Medical Informatics (AREA)
- Biochemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- Pain & Pain Management (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU9301518A HU210922B (en) | 1993-05-24 | 1993-05-24 | Nimesulide alkali salt cyclodextrin inclusion complexes their preparation and pharmaceutical compositions containing them |
| PCT/HU1994/000014 WO1994028031A1 (en) | 1993-05-24 | 1994-05-18 | New nimesulide salt cyclodextrin inclusion complexes |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO950243D0 NO950243D0 (no) | 1995-01-23 |
| NO950243L NO950243L (no) | 1995-03-13 |
| NO307570B1 true NO307570B1 (no) | 2000-04-25 |
Family
ID=10983630
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO950243A NO307570B1 (no) | 1993-05-24 | 1995-01-23 | Inklusjonskomplekser oppnådd fra nimesulidalkali- og nimesulidjordalkalisalter og cyklodekstriner eller cyklodekstrinderivater, samt farmasøytisk preparat inneholdende nevnte inklusjonskompleks og fremgangsmåte for å fremstille samme |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US5744165A (sv) |
| EP (1) | EP0656015B1 (sv) |
| JP (1) | JPH07509498A (sv) |
| KR (1) | KR950702580A (sv) |
| AT (1) | ATE170194T1 (sv) |
| AU (1) | AU675146B2 (sv) |
| CA (1) | CA2140887C (sv) |
| CZ (1) | CZ285962B6 (sv) |
| DE (1) | DE69412760T2 (sv) |
| DK (1) | DK0656015T3 (sv) |
| ES (1) | ES2124893T3 (sv) |
| FI (1) | FI950294A0 (sv) |
| HU (1) | HU210922B (sv) |
| NO (1) | NO307570B1 (sv) |
| RU (1) | RU2129564C1 (sv) |
| SI (1) | SI0656015T1 (sv) |
| WO (1) | WO1994028031A1 (sv) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU672285B2 (en) * | 1993-02-19 | 1996-09-26 | Taisho Pharmaceutical Co., Ltd. | 5-Aminoacetylaminosulfonanilide compound |
| HUP9601442A3 (en) * | 1995-07-25 | 1999-03-29 | Panacea Biotec Ltd | Nes antinflammatory and analgetic pharmaceutical compositions, containing nimesulid for transdermal use, and process for producing them |
| UA57734C2 (uk) | 1996-05-07 | 2003-07-15 | Пфайзер Інк. | Комплекси включення арилгетероциклічних солей |
| IN186315B (sv) * | 1996-12-12 | 2001-08-04 | Panacea Biotec Ltd | |
| ES2129010B1 (es) * | 1997-01-02 | 2000-01-16 | Gold Oscar | Composicion de accion prolongada en granulos que contienen 4-nitro-2- fenoximetansulfonanilida y su procedimiento de preparacion. |
| IT1291895B1 (it) | 1997-04-24 | 1999-01-21 | Errekappa Euroterapici S P A | Preparazione farmaceutica fluida a base di nimesulide per uso orale e rinofaringeo |
| IT1298221B1 (it) * | 1998-02-10 | 1999-12-20 | Helsinn Healthcare Sa | Sali micronizzati di nimesulide |
| EP1172101A1 (en) * | 2000-06-20 | 2002-01-16 | Helsinn Healthcare S.A. | The use of nimesulide for the treatment of psoriasis and psoriatic arthritis |
| IT1318588B1 (it) * | 2000-06-20 | 2003-08-27 | Helsinn Healthcare Sa | Uso della nimesulide nel trattamento di patologie dermatologiche. |
| TWI321054B (en) | 2000-12-19 | 2010-03-01 | California Inst Of Techn | Compositions containing inclusion complexes |
| EP3332811A1 (en) | 2002-09-06 | 2018-06-13 | Cerulean Pharma Inc. | Cyclodextrin-based polymers for delivering covalently attached camptothecin |
| MXPA05003591A (es) | 2002-10-09 | 2005-09-30 | Insert Therapeutics Inc | Materiales basados en ciclodextrina, composiciones y usos relacionados a los mismos. |
| CN1511828A (zh) * | 2002-12-31 | 2004-07-14 | �й������ž�����ҽѧ��ѧԺ����ҽ | 磺酰苯胺类衍生物及其医药用途 |
| DE102004060914A1 (de) * | 2004-12-17 | 2006-07-06 | Bioghurt Biogarde Gmbh & Co. Kg | Verwendung von Liponsäure-haltigen Cyclodextrin-Komplexen |
| JP2010516625A (ja) | 2007-01-24 | 2010-05-20 | インサート セラピューティクス， インコーポレイテッド | 制御された薬物送達のためのテザー基を有するポリマー−薬物コンジュゲート |
| US20140094432A1 (en) | 2012-10-02 | 2014-04-03 | Cerulean Pharma Inc. | Methods and systems for polymer precipitation and generation of particles |
| CN109608370A (zh) * | 2019-01-22 | 2019-04-12 | 山西康斯亚森生物科技有限公司 | 尼美舒利衍生物和制备方法及用途 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5920230A (ja) * | 1982-07-19 | 1984-02-01 | チバ−ガイギ−・アクチエンゲゼルシヤフト | ピルプロフエン含有薬剤 |
| GB8813682D0 (en) * | 1988-06-09 | 1988-07-13 | Reckitt & Colmann Prod Ltd | Pharmaceutical compositions |
| IT1248475B (it) * | 1990-05-22 | 1995-01-19 | Angeli Inst Spa | Composti di inclusione di nimesulide con ciclodestrine |
-
1993
- 1993-05-24 HU HU9301518A patent/HU210922B/hu not_active IP Right Cessation
-
1994
- 1994-05-18 SI SI9430204T patent/SI0656015T1/xx unknown
- 1994-05-18 DK DK94919796T patent/DK0656015T3/da active
- 1994-05-18 JP JP7500436A patent/JPH07509498A/ja active Pending
- 1994-05-18 AU AU70813/94A patent/AU675146B2/en not_active Ceased
- 1994-05-18 CA CA002140887A patent/CA2140887C/en not_active Expired - Fee Related
- 1994-05-18 US US08/374,765 patent/US5744165A/en not_active Expired - Lifetime
- 1994-05-18 RU RU95105977A patent/RU2129564C1/ru active
- 1994-05-18 DE DE69412760T patent/DE69412760T2/de not_active Expired - Fee Related
- 1994-05-18 KR KR1019950700275A patent/KR950702580A/ko not_active Application Discontinuation
- 1994-05-18 WO PCT/HU1994/000014 patent/WO1994028031A1/en active IP Right Grant
- 1994-05-18 CZ CZ95163A patent/CZ285962B6/cs not_active IP Right Cessation
- 1994-05-18 EP EP94919796A patent/EP0656015B1/en not_active Expired - Lifetime
- 1994-05-18 ES ES94919796T patent/ES2124893T3/es not_active Expired - Lifetime
- 1994-05-18 AT AT94919796T patent/ATE170194T1/de not_active IP Right Cessation
-
1995
- 1995-01-23 NO NO950243A patent/NO307570B1/no not_active IP Right Cessation
- 1995-01-24 FI FI950294A patent/FI950294A0/sv unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SI0656015T1 (en) | 1999-02-28 |
| ES2124893T3 (es) | 1999-02-16 |
| CZ285962B6 (cs) | 1999-12-15 |
| JPH07509498A (ja) | 1995-10-19 |
| EP0656015A1 (en) | 1995-06-07 |
| CZ16395A3 (en) | 1995-10-18 |
| DK0656015T3 (da) | 1999-05-25 |
| NO950243D0 (no) | 1995-01-23 |
| US5744165A (en) | 1998-04-28 |
| AU675146B2 (en) | 1997-01-23 |
| DE69412760D1 (de) | 1998-10-01 |
| AU7081394A (en) | 1994-12-20 |
| CA2140887A1 (en) | 1994-12-08 |
| FI950294A (sv) | 1995-01-24 |
| HUT68239A (en) | 1995-06-28 |
| KR950702580A (ko) | 1995-07-29 |
| HU9301518D0 (en) | 1993-09-28 |
| NO950243L (no) | 1995-03-13 |
| RU95105977A (ru) | 1997-02-10 |
| HU210922B (en) | 1995-09-28 |
| CA2140887C (en) | 2000-08-01 |
| WO1994028031A1 (en) | 1994-12-08 |
| ATE170194T1 (de) | 1998-09-15 |
| FI950294A0 (sv) | 1995-01-24 |
| RU2129564C1 (ru) | 1999-04-27 |
| EP0656015B1 (en) | 1998-08-26 |
| DE69412760T2 (de) | 1999-05-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM1K | Lapsed by not paying the annual fees |
Free format text: LAPSED IN NOVEMBER 2002 |