FI950294A - Nya inklusionskomplex av nimesulidsalt och cyklodextrin - Google Patents

Nya inklusionskomplex av nimesulidsalt och cyklodextrin Download PDF

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Publication number
FI950294A
FI950294A FI950294A FI950294A FI950294A FI 950294 A FI950294 A FI 950294A FI 950294 A FI950294 A FI 950294A FI 950294 A FI950294 A FI 950294A FI 950294 A FI950294 A FI 950294A
Authority
FI
Finland
Prior art keywords
pct
cyclodextrin
inclusion complexes
complexes
new inclusion
Prior art date
Application number
FI950294A
Other languages
English (en)
Finnish (fi)
Other versions
FI950294A0 (sv
Inventor
Joseph Geczy
Original Assignee
Europharmaceuticals Sa
Cyclolab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Europharmaceuticals Sa, Cyclolab Ltd filed Critical Europharmaceuticals Sa
Publication of FI950294A publication Critical patent/FI950294A/sv
Publication of FI950294A0 publication Critical patent/FI950294A0/sv

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/63Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0012Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
    • C08B37/0015Inclusion compounds, i.e. host-guest compounds, e.g. polyrotaxanes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Nanotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Biochemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FI950294A 1993-05-24 1995-01-24 Nya inklusionskomplex av nimesulidsalt och cyklodextrin FI950294A0 (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU9301518A HU210922B (en) 1993-05-24 1993-05-24 Nimesulide alkali salt cyclodextrin inclusion complexes their preparation and pharmaceutical compositions containing them
PCT/HU1994/000014 WO1994028031A1 (en) 1993-05-24 1994-05-18 New nimesulide salt cyclodextrin inclusion complexes

Publications (2)

Publication Number Publication Date
FI950294A true FI950294A (sv) 1995-01-24
FI950294A0 FI950294A0 (sv) 1995-01-24

Family

ID=10983630

Family Applications (1)

Application Number Title Priority Date Filing Date
FI950294A FI950294A0 (sv) 1993-05-24 1995-01-24 Nya inklusionskomplex av nimesulidsalt och cyklodextrin

Country Status (17)

Country Link
US (1) US5744165A (sv)
EP (1) EP0656015B1 (sv)
JP (1) JPH07509498A (sv)
KR (1) KR950702580A (sv)
AT (1) ATE170194T1 (sv)
AU (1) AU675146B2 (sv)
CA (1) CA2140887C (sv)
CZ (1) CZ285962B6 (sv)
DE (1) DE69412760T2 (sv)
DK (1) DK0656015T3 (sv)
ES (1) ES2124893T3 (sv)
FI (1) FI950294A0 (sv)
HU (1) HU210922B (sv)
NO (1) NO307570B1 (sv)
RU (1) RU2129564C1 (sv)
SI (1) SI0656015T1 (sv)
WO (1) WO1994028031A1 (sv)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU672285B2 (en) * 1993-02-19 1996-09-26 Taisho Pharmaceutical Co., Ltd. 5-Aminoacetylaminosulfonanilide compound
HUP9601442A3 (en) * 1995-07-25 1999-03-29 Panacea Biotec Ltd Nes antinflammatory and analgetic pharmaceutical compositions, containing nimesulid for transdermal use, and process for producing them
UA57734C2 (uk) 1996-05-07 2003-07-15 Пфайзер Інк. Комплекси включення арилгетероциклічних солей
IN186315B (sv) * 1996-12-12 2001-08-04 Panacea Biotec Ltd
ES2129010B1 (es) * 1997-01-02 2000-01-16 Gold Oscar Composicion de accion prolongada en granulos que contienen 4-nitro-2- fenoximetansulfonanilida y su procedimiento de preparacion.
IT1291895B1 (it) 1997-04-24 1999-01-21 Errekappa Euroterapici S P A Preparazione farmaceutica fluida a base di nimesulide per uso orale e rinofaringeo
IT1298221B1 (it) * 1998-02-10 1999-12-20 Helsinn Healthcare Sa Sali micronizzati di nimesulide
EP1172101A1 (en) * 2000-06-20 2002-01-16 Helsinn Healthcare S.A. The use of nimesulide for the treatment of psoriasis and psoriatic arthritis
IT1318588B1 (it) * 2000-06-20 2003-08-27 Helsinn Healthcare Sa Uso della nimesulide nel trattamento di patologie dermatologiche.
TWI321054B (en) 2000-12-19 2010-03-01 California Inst Of Techn Compositions containing inclusion complexes
EP3332811A1 (en) 2002-09-06 2018-06-13 Cerulean Pharma Inc. Cyclodextrin-based polymers for delivering covalently attached camptothecin
MXPA05003591A (es) 2002-10-09 2005-09-30 Insert Therapeutics Inc Materiales basados en ciclodextrina, composiciones y usos relacionados a los mismos.
CN1511828A (zh) * 2002-12-31 2004-07-14 �й������ž�����ҽѧ��ѧԺ����ҽ 磺酰苯胺类衍生物及其医药用途
DE102004060914A1 (de) * 2004-12-17 2006-07-06 Bioghurt Biogarde Gmbh & Co. Kg Verwendung von Liponsäure-haltigen Cyclodextrin-Komplexen
JP2010516625A (ja) 2007-01-24 2010-05-20 インサート セラピューティクス, インコーポレイテッド 制御された薬物送達のためのテザー基を有するポリマー−薬物コンジュゲート
US20140094432A1 (en) 2012-10-02 2014-04-03 Cerulean Pharma Inc. Methods and systems for polymer precipitation and generation of particles
CN109608370A (zh) * 2019-01-22 2019-04-12 山西康斯亚森生物科技有限公司 尼美舒利衍生物和制备方法及用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5920230A (ja) * 1982-07-19 1984-02-01 チバ−ガイギ−・アクチエンゲゼルシヤフト ピルプロフエン含有薬剤
GB8813682D0 (en) * 1988-06-09 1988-07-13 Reckitt & Colmann Prod Ltd Pharmaceutical compositions
IT1248475B (it) * 1990-05-22 1995-01-19 Angeli Inst Spa Composti di inclusione di nimesulide con ciclodestrine

Also Published As

Publication number Publication date
SI0656015T1 (en) 1999-02-28
ES2124893T3 (es) 1999-02-16
CZ285962B6 (cs) 1999-12-15
JPH07509498A (ja) 1995-10-19
EP0656015A1 (en) 1995-06-07
CZ16395A3 (en) 1995-10-18
DK0656015T3 (da) 1999-05-25
NO950243D0 (no) 1995-01-23
US5744165A (en) 1998-04-28
AU675146B2 (en) 1997-01-23
DE69412760D1 (de) 1998-10-01
AU7081394A (en) 1994-12-20
NO307570B1 (no) 2000-04-25
CA2140887A1 (en) 1994-12-08
HUT68239A (en) 1995-06-28
KR950702580A (ko) 1995-07-29
HU9301518D0 (en) 1993-09-28
NO950243L (no) 1995-03-13
RU95105977A (ru) 1997-02-10
HU210922B (en) 1995-09-28
CA2140887C (en) 2000-08-01
WO1994028031A1 (en) 1994-12-08
ATE170194T1 (de) 1998-09-15
FI950294A0 (sv) 1995-01-24
RU2129564C1 (ru) 1999-04-27
EP0656015B1 (en) 1998-08-26
DE69412760T2 (de) 1999-05-20

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