NO307445B1 - Farmasøytiske preparater inneholdende nanokapsler og fremgangsmõte for fremstilling derav - Google Patents

Farmasøytiske preparater inneholdende nanokapsler og fremgangsmõte for fremstilling derav

Info

Publication number
NO307445B1
NO307445B1 NO940111A NO940111A NO307445B1 NO 307445 B1 NO307445 B1 NO 307445B1 NO 940111 A NO940111 A NO 940111A NO 940111 A NO940111 A NO 940111A NO 307445 B1 NO307445 B1 NO 307445B1
Authority
NO
Norway
Prior art keywords
nanocapsules
preparation
suspension
processes
pharmaceutical preparations
Prior art date
Application number
NO940111A
Other languages
English (en)
Norwegian (no)
Other versions
NO940111D0 (no
NO940111L (no
Inventor
Henri Vranckx
Martine Demoustier
Michel Deleers
Original Assignee
Ucb Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ucb Sa filed Critical Ucb Sa
Publication of NO940111D0 publication Critical patent/NO940111D0/no
Publication of NO940111L publication Critical patent/NO940111L/no
Publication of NO307445B1 publication Critical patent/NO307445B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5138—Organic macromolecular compounds; Dendrimers obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727—Heparin; Heparan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5169—Proteins, e.g. albumin, gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5192—Processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/06—Making microcapsules or microballoons by phase separation
    • B01J13/14—Polymerisation; cross-linking
    • B01J13/18—In situ polymerisation with all reactants being present in the same phase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984—Microcapsule with fluid core [includes liposome]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984—Microcapsule with fluid core [includes liposome]
    • Y10T428/2985—Solid-walled microcapsule from synthetic polymer

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Optics & Photonics (AREA)
  • Nanotechnology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Cosmetics (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
NO940111A 1993-01-18 1994-01-12 Farmasøytiske preparater inneholdende nanokapsler og fremgangsmõte for fremstilling derav NO307445B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB939300875A GB9300875D0 (en) 1993-01-18 1993-01-18 Nanocapsule containing pharmaceutical compositions

Publications (3)

Publication Number Publication Date
NO940111D0 NO940111D0 (no) 1994-01-12
NO940111L NO940111L (no) 1994-07-19
NO307445B1 true NO307445B1 (no) 2000-04-10

Family

ID=10728864

Family Applications (1)

Application Number Title Priority Date Filing Date
NO940111A NO307445B1 (no) 1993-01-18 1994-01-12 Farmasøytiske preparater inneholdende nanokapsler og fremgangsmõte for fremstilling derav

Country Status (21)

Country Link
US (1) US5500224A (fi)
EP (1) EP0608207B1 (fi)
JP (1) JP3688731B2 (fi)
KR (1) KR100311056B1 (fi)
AT (1) ATE172111T1 (fi)
AU (1) AU670840B2 (fi)
CA (1) CA2113243C (fi)
CY (1) CY2132B1 (fi)
DE (1) DE69413857T2 (fi)
DK (1) DK0608207T3 (fi)
ES (1) ES2122217T3 (fi)
FI (1) FI111441B (fi)
GB (1) GB9300875D0 (fi)
HU (1) HUT67213A (fi)
NO (1) NO307445B1 (fi)
NZ (1) NZ250673A (fi)
PL (1) PL173254B1 (fi)
RU (1) RU2145498C1 (fi)
SG (1) SG43682A1 (fi)
TW (1) TW336174B (fi)
ZA (1) ZA94205B (fi)

Families Citing this family (48)

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FR2721510B1 (fr) * 1994-06-22 1996-07-26 Rhone Poulenc Rorer Sa Nanoparticules filtrables dans des conditions stériles.
ATE198148T1 (de) * 1995-02-06 2001-01-15 Elan Pharma Int Ltd Formulierungen von verbindungen als nanopartikel dispergiert in verdaubaren ölen oder fettsäuren
JP3759986B2 (ja) * 1995-12-07 2006-03-29 フロイント産業株式会社 シームレスカプセルおよびその製造方法
FR2766368B1 (fr) * 1997-07-24 2000-03-31 Univ Claude Bernard Lyon Procede de preparation de nanocapsules de type vesiculaire, utilisables notamment comme vecteurs colloidaux de principes actifs pharmaceutiques ou autres
US6761903B2 (en) 1999-06-30 2004-07-13 Lipocine, Inc. Clear oil-containing pharmaceutical compositions containing a therapeutic agent
US6248363B1 (en) * 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
US6982281B1 (en) * 2000-11-17 2006-01-03 Lipocine Inc Pharmaceutical compositions and dosage forms for administration of hydrophobic drugs
US20030236236A1 (en) * 1999-06-30 2003-12-25 Feng-Jing Chen Pharmaceutical compositions and dosage forms for administration of hydrophobic drugs
US6458383B2 (en) 1999-08-17 2002-10-01 Lipocine, Inc. Pharmaceutical dosage form for oral administration of hydrophilic drugs, particularly low molecular weight heparin
JP4751556B2 (ja) * 2000-02-28 2011-08-17 ジーンシーグス， インコーポレイテッド ナノカプセルカプセル化システムおよび方法
FR2806005B1 (fr) * 2000-03-10 2002-06-14 Univ Claude Bernard Lyon Procede de preparation de particules colloidales sous forme de nanocapsules
US7153525B1 (en) * 2000-03-22 2006-12-26 The University Of Kentucky Research Foundation Microemulsions as precursors to solid nanoparticles
CN1531436A (zh) * 2001-05-09 2004-09-22 (株)美大富历寿 用于增强粘膜吸收的两亲肝素衍生物制剂
WO2003024425A1 (en) * 2001-09-19 2003-03-27 Elan Pharma International, Ltd. Nanoparticulate insulin formulations
ATE424815T1 (de) * 2001-12-03 2009-03-15 Dor Biopharma Inc Stabilisierte umkehr-mizellen-zusammensetzungen und ihre verwendung
US20040038303A1 (en) * 2002-04-08 2004-02-26 Unger Gretchen M. Biologic modulations with nanoparticles
TR200500108T2 (tr) 2002-07-18 2005-04-21 Helix Biopharma Corp. Kanser Hücresi Gelişiminin İnhibe Edilmesinde Üreaz Kullanımı
WO2004053056A2 (en) * 2002-09-24 2004-06-24 University Of Kentucky Research Foundation Nanoparticle-based vaccine delivery system containing adjuvant
JP2006521366A (ja) * 2003-03-28 2006-09-21 シグモイド・バイオテクノロジーズ・リミテッド シームレスマイクロカプセルを含む固形経口剤形
US20060003002A1 (en) * 2003-11-03 2006-01-05 Lipocine, Inc. Pharmaceutical compositions with synchronized solubilizer release
WO2006035418A2 (en) * 2004-09-27 2006-04-06 Sigmoid Biotechnologies Limited Microcapsules comprising a methylxanthine and a corticosteroid
FR2899800B1 (fr) * 2006-04-13 2008-10-10 Oreal Emulsion eau dans l'huile pour le traitement des fibres keratiniques comprenant un monomere cyanoacrylate
FR2899797A1 (fr) * 2006-04-13 2007-10-19 Oreal Emulsion eau dans l'huile pour le traitement des fibres keratiniques comprenant un monomere cyanoacrylate et de l'ammoniaque
ES2393814T3 (es) 2007-04-04 2012-12-28 Sigmoid Pharma Limited Una composición farmacéutica oral
WO2008132707A1 (en) * 2007-04-26 2008-11-06 Sigmoid Pharma Limited Manufacture of multiple minicapsules
CA2685593A1 (en) * 2007-05-01 2008-11-06 Sigmoid Pharma Limited Combination pharmaceutical compositions
US8861813B2 (en) * 2008-03-13 2014-10-14 Mallinckrodt Llc Multi-function, foot-activated controller for imaging system
EP2273986A2 (en) * 2008-05-06 2011-01-19 Glaxo Group Limited Encapsulation of biologically active agents
US11304960B2 (en) 2009-01-08 2022-04-19 Chandrashekar Giliyar Steroidal compositions
DK2471518T3 (en) 2009-05-18 2017-12-04 Sigmoid Pharma Ltd COMPOSITION INCLUDING OIL DROPS
IN2012DN00781A (fi) 2009-08-12 2015-06-26 Sigmoid Pharma Ltd
GB201020032D0 (en) 2010-11-25 2011-01-12 Sigmoid Pharma Ltd Composition
US9034858B2 (en) 2010-11-30 2015-05-19 Lipocine Inc. High-strength testosterone undecanoate compositions
US9358241B2 (en) 2010-11-30 2016-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US20180153904A1 (en) 2010-11-30 2018-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US20120148675A1 (en) 2010-12-10 2012-06-14 Basawaraj Chickmath Testosterone undecanoate compositions
GB201212010D0 (en) 2012-07-05 2012-08-22 Sigmoid Pharma Ltd Formulations
RU2566069C2 (ru) * 2013-05-31 2015-10-20 Общество с ограниченной ответственностью "Изварино Фарма" Система доставки вещества белковой природы в виде наночастиц и способ ее получения
GB201319791D0 (en) 2013-11-08 2013-12-25 Sigmoid Pharma Ltd Formulations
CN106794150B (zh) * 2014-05-30 2021-12-28 艾伯维德国有限责任两合公司 高药物负载的聚(2-氰基丙烯酸烷基酯)纳米胶囊
WO2016033549A2 (en) 2014-08-28 2016-03-03 Lipocine Inc. (17-ß)-3-OXOANDROST-4-EN-17-YL TRIDECANOATE COMPOSITIONS AND METHODS OF THEIR PREPARATION AND USE
US9498485B2 (en) 2014-08-28 2016-11-22 Lipocine Inc. Bioavailable solid state (17-β)-hydroxy-4-androsten-3-one esters
US10987308B2 (en) 2014-09-03 2021-04-27 Genesegues, Inc. Therapeutic nanoparticles and related compositions, methods and systems
EP3881829A1 (en) 2014-11-07 2021-09-22 Sublimity Therapeutics Limited Compositions comprising cyclosporin
BR112017015582A2 (pt) 2015-01-23 2018-03-13 Helix Biopharma Corp conjugados de anticorpo-urease para propósitos terapêuticos
RU2590651C1 (ru) * 2015-03-30 2016-07-10 Александр Александрович Кролевец Способ получения нанокапсул рибофлавина в геллановой камеди
EP3544614A4 (en) 2016-11-28 2020-08-05 Lipocine Inc. ORAL TESTOSTERONE UNDECANOATE THERAPY
WO2023089240A1 (en) * 2021-11-19 2023-05-25 Nanoform Finland Oyj A composition comprising nanosized active pharmaceutical ingredient

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FR2515960A1 (fr) * 1981-11-06 1983-05-13 Alkhouri Fallouh Nazir Nanocapsules ou nanoparticules biodegradables contenant une substance biologiquement active, leur preparation et leur application
JPS6061521A (ja) * 1983-09-16 1985-04-09 Kyowa Hakko Kogyo Co Ltd マイクロカプセル化製剤
DE3341001A1 (de) * 1983-11-12 1985-05-23 Krause, Hans Jürgen Nanopartikel aus bioabbaubarem, synthetischem material, verfahren zu deren herstellung und ihre anwendung
FR2659554B1 (fr) * 1990-03-16 1994-09-30 Oreal Composition pour le traitement cosmetique et/ou pharmaceutique des couches superieures de l'epiderme par application topique sur la peau et procede de preparation correspondant.

Also Published As

Publication number Publication date
HU9400107D0 (en) 1994-05-30
FI940115A0 (fi) 1994-01-11
RU2145498C1 (ru) 2000-02-20
US5500224A (en) 1996-03-19
ZA94205B (en) 1994-08-22
KR100311056B1 (ko) 2002-03-21
HUT67213A (en) 1995-03-28
KR940018086A (ko) 1994-08-16
RU94002474A (ru) 1996-11-10
JP3688731B2 (ja) 2005-08-31
NO940111D0 (no) 1994-01-12
PL173254B1 (pl) 1998-02-27
FI111441B (fi) 2003-07-31
GB9300875D0 (en) 1993-03-10
CA2113243A1 (en) 1994-07-19
ES2122217T3 (es) 1998-12-16
JPH06256172A (ja) 1994-09-13
SG43682A1 (en) 1997-11-14
DE69413857T2 (de) 1999-04-15
NZ250673A (en) 1994-11-25
CA2113243C (en) 2008-08-05
EP0608207A1 (fr) 1994-07-27
NO940111L (no) 1994-07-19
EP0608207B1 (fr) 1998-10-14
FI940115A (fi) 1994-07-19
PL301841A1 (en) 1994-07-25
DK0608207T3 (da) 1999-06-23
AU670840B2 (en) 1996-08-01
ATE172111T1 (de) 1998-10-15
DE69413857D1 (de) 1998-11-19
TW336174B (en) 1998-07-11
CY2132B1 (en) 2002-06-21
AU5309794A (en) 1994-07-21

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