NO307377B1 - Pyridyltioforbindelser for bekjempelse av Helicobacter- bakterier - Google Patents
Pyridyltioforbindelser for bekjempelse av Helicobacter- bakterierInfo
- Publication number
- NO307377B1 NO307377B1 NO970225A NO970225A NO307377B1 NO 307377 B1 NO307377 B1 NO 307377B1 NO 970225 A NO970225 A NO 970225A NO 970225 A NO970225 A NO 970225A NO 307377 B1 NO307377 B1 NO 307377B1
- Authority
- NO
- Norway
- Prior art keywords
- pct
- helicobacter bacteria
- pyridylthio
- compounds
- control
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/70—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH230394 | 1994-07-20 | ||
| PCT/EP1995/002851 WO1996002505A1 (de) | 1994-07-20 | 1995-07-19 | Pyridylthioverbindungen zur bekämpfung von helicobacter-bakterien |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO970225D0 NO970225D0 (no) | 1997-01-17 |
| NO970225L NO970225L (no) | 1997-03-17 |
| NO307377B1 true NO307377B1 (no) | 2000-03-27 |
Family
ID=4230644
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO970225A NO307377B1 (no) | 1994-07-20 | 1997-01-17 | Pyridyltioforbindelser for bekjempelse av Helicobacter- bakterier |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US6162809A (cs) |
| EP (1) | EP0772593B1 (cs) |
| JP (1) | JPH10502660A (cs) |
| KR (1) | KR970704688A (cs) |
| CN (1) | CN1157610A (cs) |
| AT (1) | ATE238990T1 (cs) |
| AU (1) | AU702609B2 (cs) |
| BG (1) | BG62401B1 (cs) |
| CA (1) | CA2195444A1 (cs) |
| CZ (1) | CZ288524B6 (cs) |
| DE (1) | DE59510667D1 (cs) |
| FI (1) | FI970203A0 (cs) |
| HU (1) | HUT76639A (cs) |
| NO (1) | NO307377B1 (cs) |
| NZ (1) | NZ290422A (cs) |
| PL (1) | PL318298A1 (cs) |
| RU (1) | RU2149872C1 (cs) |
| SK (1) | SK281683B6 (cs) |
| WO (1) | WO1996002505A1 (cs) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA56992C2 (uk) * | 1995-05-08 | 2003-06-16 | Фармація Енд Апджон Компані | <font face="Symbol">a</font>-ПІРИМІДИНТІОАЛКІЛЗАМІЩЕНІ ТА <font face="Symbol">a</font>-ПІРИМІДИНОКСОАЛКІЛЗАМІЩЕНІ СПОЛУКИ |
| US6362009B1 (en) | 1997-11-21 | 2002-03-26 | Merck & Co., Inc. | Solid phase synthesis of heterocycles |
| US6479514B1 (en) | 1998-05-23 | 2002-11-12 | Altana Pharma Ag | Quinoline-aminomethyl-pyridyl derivatives with anti-helicobacter activity |
| EP1091957B1 (en) * | 1998-05-23 | 2004-12-15 | ALTANA Pharma AG | Pyrimidin-aminomethyl-pyridine derivatives, their preparation and their use in the control of helicobacter bacteria |
| US6904489B2 (en) * | 2001-10-23 | 2005-06-07 | Digi International Inc. | Methods and systems for remotely accessing universal serial bus devices |
| ZA200701232B (en) | 2004-07-15 | 2008-08-27 | Amr Technology Inc | Aryl-and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine and serotonin |
| JP5053992B2 (ja) * | 2006-03-10 | 2012-10-24 | アリジェン製薬株式会社 | 抗ヘリコバクター・ピロリ作用を有する新規ピリジン誘導体 |
| ES2390611T3 (es) * | 2006-12-18 | 2012-11-14 | Arigen Pharmaceuticals, Inc. | Agente de erradicación de Helicobacter pylori que tiene actividad inhibidora sobre la secreción de ácido gástrico |
| US9156812B2 (en) | 2008-06-04 | 2015-10-13 | Bristol-Myers Squibb Company | Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine |
| CN101486706B (zh) * | 2009-03-09 | 2012-12-19 | 邓菊娟 | 一种奥美拉唑钠化合物及其合成方法 |
| CA2760837C (en) * | 2009-05-12 | 2018-04-03 | Albany Molecular Research, Inc. | 7-([1,2,4]triazolo[1,5-.alpha.]pyridin-6-yl)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroisoquinoline and use thereof |
| WO2010132437A1 (en) | 2009-05-12 | 2010-11-18 | Albany Molecular Research, Inc. | Aryl, heteroaryl, and heterocycle substituted tetrahydroisoquinolines and use thereof |
| JP5739415B2 (ja) | 2009-05-12 | 2015-06-24 | ブリストル−マイヤーズ スクウィブ カンパニー | （Ｓ）−７−（［１，２，４］トリアゾロ［１，５−ａ］ピリジン−６−イル）−４−（３，４−ジクロロフェニル）−１，２，３，４−テトラヒドロイソキノリンの結晶形態およびその使用 |
| AU2011261375B2 (en) | 2010-06-04 | 2016-09-22 | Albany Molecular Research, Inc. | Glycine transporter-1 inhibitors, methods of making them, and uses thereof |
| CN105622599B (zh) * | 2016-03-01 | 2018-08-31 | 浙江工业大学 | 一种2-取代苄硫基-5-(4,6-二甲基嘧啶-2-)硫甲基-1,3,4-噻二唑类化合物及其应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS62209062A (ja) * | 1986-03-10 | 1987-09-14 | Yamanouchi Pharmaceut Co Ltd | ２−ピリジルメチルチオ−または２−ピリジルメチルスルフイニル−置換縮合環化合物 |
| EP0673246A1 (de) * | 1992-12-10 | 1995-09-27 | Byk Gulden Lomberg Chemische Fabrik GmbH | Verwendung von alkylthiopyridinen zur bekämpfung von heliobacter-bakterien |
-
1995
- 1995-07-19 NZ NZ290422A patent/NZ290422A/xx unknown
- 1995-07-19 EP EP95926959A patent/EP0772593B1/de not_active Expired - Lifetime
- 1995-07-19 SK SK1687-96A patent/SK281683B6/sk unknown
- 1995-07-19 CZ CZ1997170A patent/CZ288524B6/cs not_active IP Right Cessation
- 1995-07-19 AU AU31155/95A patent/AU702609B2/en not_active Ceased
- 1995-07-19 HU HU9700023A patent/HUT76639A/hu unknown
- 1995-07-19 CN CN95195063A patent/CN1157610A/zh active Pending
- 1995-07-19 WO PCT/EP1995/002851 patent/WO1996002505A1/de active IP Right Grant
- 1995-07-19 AT AT95926959T patent/ATE238990T1/de not_active IP Right Cessation
- 1995-07-19 DE DE59510667T patent/DE59510667D1/de not_active Expired - Fee Related
- 1995-07-19 PL PL95318298A patent/PL318298A1/xx unknown
- 1995-07-19 RU RU97102557A patent/RU2149872C1/ru active
- 1995-07-19 KR KR1019970700444A patent/KR970704688A/ko not_active Application Discontinuation
- 1995-07-19 JP JP8504717A patent/JPH10502660A/ja active Pending
- 1995-07-19 US US08/776,047 patent/US6162809A/en not_active Expired - Fee Related
- 1995-07-19 CA CA002195444A patent/CA2195444A1/en not_active Abandoned
-
1997
- 1997-01-06 BG BG101109A patent/BG62401B1/bg unknown
- 1997-01-17 FI FI970203A patent/FI970203A0/fi unknown
- 1997-01-17 NO NO970225A patent/NO307377B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| SK281683B6 (sk) | 2001-06-11 |
| JPH10502660A (ja) | 1998-03-10 |
| US6162809A (en) | 2000-12-19 |
| SK168796A3 (en) | 1997-09-10 |
| WO1996002505A1 (de) | 1996-02-01 |
| NO970225D0 (no) | 1997-01-17 |
| FI970203A (fi) | 1997-01-17 |
| EP0772593A1 (de) | 1997-05-14 |
| FI970203A0 (fi) | 1997-01-17 |
| ATE238990T1 (de) | 2003-05-15 |
| CA2195444A1 (en) | 1996-02-01 |
| HUT76639A (en) | 1997-10-28 |
| BG101109A (en) | 1997-08-29 |
| NO970225L (no) | 1997-03-17 |
| HU9700023D0 (en) | 1997-02-28 |
| NZ290422A (en) | 1999-02-25 |
| AU702609B2 (en) | 1999-02-25 |
| KR970704688A (ko) | 1997-09-06 |
| CZ288524B6 (cs) | 2001-07-11 |
| DE59510667D1 (de) | 2003-06-05 |
| CN1157610A (zh) | 1997-08-20 |
| EP0772593B1 (de) | 2003-05-02 |
| CZ17097A3 (en) | 1997-09-17 |
| PL318298A1 (en) | 1997-06-09 |
| BG62401B1 (bg) | 1999-10-29 |
| RU2149872C1 (ru) | 2000-05-27 |
| AU3115595A (en) | 1996-02-16 |
| MX9700524A (es) | 1998-05-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM1K | Lapsed by not paying the annual fees |
Free format text: LAPSED IN JANUARY 2003 |