NO963988D0 - Hypokolesterolemiske-, antiatherosklerotiske-, og hypotriglyceridemiske mercaptoacetylamidderivater - Google Patents

Hypokolesterolemiske-, antiatherosklerotiske-, og hypotriglyceridemiske mercaptoacetylamidderivater

Info

Publication number
NO963988D0
NO963988D0 NO963988A NO963988A NO963988D0 NO 963988 D0 NO963988 D0 NO 963988D0 NO 963988 A NO963988 A NO 963988A NO 963988 A NO963988 A NO 963988A NO 963988 D0 NO963988 D0 NO 963988D0
Authority
NO
Norway
Prior art keywords
pct
hypotriglyceridemic
hypocholesterolemic
atherosclerotic
sec
Prior art date
Application number
NO963988A
Other languages
English (en)
Other versions
NO963988L (no
Inventor
Gary Alan Flynn
John Fitzhugh French
Richard Cyrus Dage
Original Assignee
Merrell Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Pharma Inc filed Critical Merrell Pharma Inc
Publication of NO963988D0 publication Critical patent/NO963988D0/no
Publication of NO963988L publication Critical patent/NO963988L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06—Tripeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05—Dipeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
NO963988A 1994-03-24 1996-09-23 Hypokolesterolemiske-, antiatherosklerotiske-, og hypotriglyceridemiske mercaptoacetylamidderivater NO963988L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21747194A 1994-03-24 1994-03-24
PCT/US1995/002448 WO1995025519A1 (en) 1994-03-24 1995-02-28 Hypocholesterolemic, antiatherosclerotic and hypotriglyceridemic mercaptoacetylamide disulfide derivatives

Publications (2)

Publication Number Publication Date
NO963988D0 true NO963988D0 (no) 1996-09-23
NO963988L NO963988L (no) 1996-11-22

Family

ID=22811224

Family Applications (1)

Application Number Title Priority Date Filing Date
NO963988A NO963988L (no) 1994-03-24 1996-09-23 Hypokolesterolemiske-, antiatherosklerotiske-, og hypotriglyceridemiske mercaptoacetylamidderivater

Country Status (18)

Country Link
US (1) US6013645A (no)
EP (1) EP0751774B1 (no)
JP (1) JPH10503468A (no)
CN (1) CN1144482A (no)
AT (1) ATE246927T1 (no)
AU (1) AU688012B2 (no)
CA (1) CA2184692C (no)
DE (1) DE69531489T2 (no)
DK (1) DK0751774T3 (no)
ES (1) ES2201100T3 (no)
FI (1) FI963784A0 (no)
HU (1) HUP9774624A2 (no)
IL (1) IL113073A (no)
NO (1) NO963988L (no)
NZ (1) NZ282565A (no)
PT (1) PT751774E (no)
WO (1) WO1995025519A1 (no)
ZA (1) ZA952289B (no)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6667299B1 (en) * 2000-03-16 2003-12-23 Hollis-Eden Pharmaceuticals, Inc. Pharmaceutical compositions and treatment methods
GB0119305D0 (en) * 2001-04-12 2001-10-03 Aventis Pharma Gmbh Mercaptoacetylamide derivatives,a process for their preparation and their use

Family Cites Families (29)

* Cited by examiner, † Cited by third party
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US3334095A (en) * 1965-02-16 1967-08-01 Sandoz Ag Novel pyrrolo-oxazines and pyrrolo-oxazoles
US3334091A (en) * 1965-03-25 1967-08-01 Sandoz Ag Sedatives
GB1525845A (en) * 1976-07-30 1978-09-20 Ucb Sa 1,2,4,5-tetrahydro-3h-2-benzazepin-3-ones
IE50839B1 (en) * 1980-02-26 1986-07-23 Wyeth John & Brother Ltd Novel processes for preparing proline derivatives and analogous compounds
EP0042100A1 (de) * 1980-06-13 1981-12-23 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Pyrazolopyridazin-Derivate, Zwischenprodukte und Verfahren zu deren Herstellung, sowie diese enthaltende Arzneimittel
US4320057A (en) * 1980-06-23 1982-03-16 American Home Products Corporation Aryl--pyrrolo--thiazepin--diones and aryl--piperidino--thiazepin--diones
US4415496A (en) * 1981-03-23 1983-11-15 Merck & Co., Inc. Bicyclic lactams
NZ204130A (en) * 1982-05-12 1986-03-14 Hoffmann La Roche Bicyclic heterocyclic compounds and pharmaceutical compositions
GB2128984B (en) * 1982-05-12 1985-05-22 Hoffmann La Roche Diaza-bicyclic compounds
US4552889A (en) * 1983-06-09 1985-11-12 Eli Lilly And Company 3-Mercaptomethyl-2-oxo-1-pyrrolidine acetic acids and use for hypertension
US4692438A (en) * 1984-08-24 1987-09-08 Hoffmann-La Roche Inc. Pyridazo-diazepines, diazocines, and -triazepines having anti-hypertensive activity
US4584294A (en) * 1984-11-07 1986-04-22 Merck & Co., Inc. Fused tricyclic lactams as angiotensin converting enzyme inhibitors and as antihypertensive agents
KR880001092B1 (ko) * 1985-04-30 1988-06-23 일라이 릴리 앤드 캄파니 7-치환된 바이시클릭 피라졸리디논 및 그의 제조방법
ZA874106B (en) * 1986-06-13 1987-12-08 Merrell Dow Pharmaceuticals Inc. Novel antihypertensive agent
US4973585A (en) * 1986-06-13 1990-11-27 Merrell Dow Pharmaceuticals Tricyclic lactams active as antihypertensive agents
CA1337654C (en) * 1986-06-13 1995-11-28 Gary A. Flynn Fused tricyclic lactams as antihypertensive agents
GB8629875D0 (en) * 1986-12-15 1987-01-28 Hoffmann La Roche Pyridazodiazepine derivatives
US4824832A (en) * 1987-12-30 1989-04-25 Merrell Dow Pharmaceuticals Inc. Sulfhydryl containing tricyclic lactams and their pharmacological methods of use
US4902684A (en) * 1988-06-20 1990-02-20 E. R. Squibb & Sons, Inc. Benzazepine and benzothiazepine derivatives
GB8926512D0 (en) * 1989-11-23 1990-01-10 Pfizer Ltd Therapeutic agents
US5407960A (en) * 1989-12-22 1995-04-18 Schering Corporation Mercaptocycloacyl aminoacid endopeptidase inhibitors
ATE195653T1 (de) * 1990-06-06 2000-09-15 Ruth Korth Behandlung von erkrankungen mit paf-antagonisten und verfahren zur bestimmung deren wirksamkeit
CA2053340C (en) * 1990-10-18 2002-04-02 Timothy P. Burkholder Mercaptoacetylamide derivatives useful as inhibitors of enkephalinase and ace
US5208230A (en) * 1990-12-21 1993-05-04 Merrell Dow Pharmaceuticals Amino and nitro containing tricyclic compounds useful as inhibitors of ACE
ATE158303T1 (de) * 1990-12-21 1997-10-15 Merrell Pharma Inc Neue trizyklische amino- und nitro verbindungen mit ace-hemmenden eigenschaften
FR2679564A1 (fr) * 1991-07-23 1993-01-29 Inst Nat Sante Rech Med Nouveaux acylmercaptoalcanoldipeptides, leur preparation et les compositions qui les contiennent.
ATE235474T1 (de) * 1992-04-20 2003-04-15 Takeda Chemical Industries Ltd 4,1-benzoxazepinderivate als squalen-synthetase inhibitoren und ihre verwendung zur behandlung von hypercholesterämie und als fungizide
RU2124503C1 (ru) * 1992-05-18 1999-01-10 И.Р.Сквибб энд Санз, Инк. Гетероциклические азотсодержащие производные карбоновой кислоты, способ их получения и фармацевтическая композиция
US5238932A (en) * 1992-05-20 1993-08-24 Merrell Dow Pharmaceuticals Inc. Mercaptoacetylamide tricyclic derivatives useful as inhibitors of enkephalinase

Also Published As

Publication number Publication date
CA2184692C (en) 2001-01-02
JPH10503468A (ja) 1998-03-31
AU688012B2 (en) 1998-03-05
DE69531489T2 (de) 2004-04-08
FI963784A (fi) 1996-09-23
AU1972095A (en) 1995-10-09
US6013645A (en) 2000-01-11
WO1995025519A1 (en) 1995-09-28
IL113073A0 (en) 1995-06-29
CN1144482A (zh) 1997-03-05
NO963988L (no) 1996-11-22
FI963784A0 (fi) 1996-09-23
PT751774E (pt) 2003-11-28
DK0751774T3 (da) 2003-12-08
NZ282565A (en) 1999-11-29
EP0751774B1 (en) 2003-08-13
EP0751774A1 (en) 1997-01-08
ES2201100T3 (es) 2004-03-16
ZA952289B (en) 1996-01-09
ATE246927T1 (de) 2003-08-15
DE69531489D1 (de) 2003-09-18
HUP9774624A2 (en) 1997-01-28
HU9602602D0 (en) 1996-11-28
CA2184692A1 (en) 1995-09-28
IL113073A (en) 2001-03-19

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application