DK0751775T3 - Hypocholesterolæmiske, antiatherosclerotiske og hypotriglyceridæmiske mercaptoacetylamidderivater - Google Patents
Hypocholesterolæmiske, antiatherosclerotiske og hypotriglyceridæmiske mercaptoacetylamidderivaterInfo
- Publication number
- DK0751775T3 DK0751775T3 DK95913501T DK95913501T DK0751775T3 DK 0751775 T3 DK0751775 T3 DK 0751775T3 DK 95913501 T DK95913501 T DK 95913501T DK 95913501 T DK95913501 T DK 95913501T DK 0751775 T3 DK0751775 T3 DK 0751775T3
- Authority
- DK
- Denmark
- Prior art keywords
- hypotriglyceridemic
- antiatherosclerotic
- hypocholesterolemic
- mercaptoacetylamide
- derivatives
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Peptides Or Proteins (AREA)
- Artificial Filaments (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/217,781 US5484783A (en) | 1994-03-24 | 1994-03-24 | Hypocholesterolemic, antiatherosclerotic and hypotriglyceridemic mercaptoacetylamide and benzazapine derivatives |
PCT/US1995/002476 WO1995025548A2 (en) | 1994-03-24 | 1995-02-28 | Hypocholesterolemic, antiatherosclerotic and hypotriglyceridemic mercaptoacetylamide derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0751775T3 true DK0751775T3 (da) | 2002-08-26 |
Family
ID=22812484
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK95913501T DK0751775T3 (da) | 1994-03-24 | 1995-02-28 | Hypocholesterolæmiske, antiatherosclerotiske og hypotriglyceridæmiske mercaptoacetylamidderivater |
Country Status (20)
Country | Link |
---|---|
US (1) | US5484783A (da) |
EP (1) | EP0751775B1 (da) |
JP (1) | JPH09510220A (da) |
KR (1) | KR970701550A (da) |
CN (1) | CN1144483A (da) |
AT (1) | ATE217527T1 (da) |
AU (1) | AU705029B2 (da) |
CA (1) | CA2184693C (da) |
DE (1) | DE69526731T2 (da) |
DK (1) | DK0751775T3 (da) |
ES (1) | ES2173180T3 (da) |
FI (1) | FI118414B (da) |
HU (1) | HU226643B1 (da) |
IL (1) | IL113074A (da) |
NO (1) | NO313176B1 (da) |
NZ (1) | NZ282949A (da) |
PT (1) | PT751775E (da) |
TW (1) | TW323954B (da) |
WO (1) | WO1995025548A2 (da) |
ZA (1) | ZA952285B (da) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6635632B1 (en) | 1996-12-23 | 2003-10-21 | Athena Neurosciences, Inc. | Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds |
US5834353A (en) * | 1997-10-20 | 1998-11-10 | Texas Instruments-Acer Incorporated | Method of making deep sub-micron meter MOSFET with a high permitivity gate dielectric |
US6378430B1 (en) | 1999-10-15 | 2002-04-30 | King Press Corporation | Cylinder with plate gripping device |
DE10229180A1 (de) * | 2002-06-28 | 2004-01-29 | Aventis Pharma Deutschland Gmbh | Verwendung von Vasopeptidase-Inhibitoren bei der Behandlung von metabolischen Erkrankungen, Nephropathie und mit AGE assoziierten Erkrankungen |
AU2004282101A1 (en) * | 2003-10-08 | 2005-04-28 | Eli Lilly And Company | Compounds and methods for treating dyslipidemia |
Family Cites Families (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3334095A (en) * | 1965-02-16 | 1967-08-01 | Sandoz Ag | Novel pyrrolo-oxazines and pyrrolo-oxazoles |
US3334091A (en) * | 1965-03-25 | 1967-08-01 | Sandoz Ag | Sedatives |
GB1525845A (en) * | 1976-07-30 | 1978-09-20 | Ucb Sa | 1,2,4,5-tetrahydro-3h-2-benzazepin-3-ones |
IE50839B1 (en) * | 1980-02-26 | 1986-07-23 | Wyeth John & Brother Ltd | Novel processes for preparing proline derivatives and analogous compounds |
EP0042100A1 (de) * | 1980-06-13 | 1981-12-23 | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft | Pyrazolopyridazin-Derivate, Zwischenprodukte und Verfahren zu deren Herstellung, sowie diese enthaltende Arzneimittel |
US4320057A (en) * | 1980-06-23 | 1982-03-16 | American Home Products Corporation | Aryl--pyrrolo--thiazepin--diones and aryl--piperidino--thiazepin--diones |
US4415496A (en) * | 1981-03-23 | 1983-11-15 | Merck & Co., Inc. | Bicyclic lactams |
GB2128984B (en) * | 1982-05-12 | 1985-05-22 | Hoffmann La Roche | Diaza-bicyclic compounds |
ZA833214B (en) * | 1982-05-12 | 1983-12-28 | Hoffmann La Roche | Bicyclic compounds |
US4552889A (en) * | 1983-06-09 | 1985-11-12 | Eli Lilly And Company | 3-Mercaptomethyl-2-oxo-1-pyrrolidine acetic acids and use for hypertension |
US4692438A (en) * | 1984-08-24 | 1987-09-08 | Hoffmann-La Roche Inc. | Pyridazo-diazepines, diazocines, and -triazepines having anti-hypertensive activity |
US4584294A (en) * | 1984-11-07 | 1986-04-22 | Merck & Co., Inc. | Fused tricyclic lactams as angiotensin converting enzyme inhibitors and as antihypertensive agents |
AU5675586A (en) * | 1985-04-30 | 1986-11-13 | Eli Lilly And Company | 1,5-diazabicyclo (3.3.0) octa-2-ene derivatives |
ZA874106B (en) * | 1986-06-13 | 1987-12-08 | Merrell Dow Pharmaceuticals Inc. | Novel antihypertensive agent |
US4973585A (en) * | 1986-06-13 | 1990-11-27 | Merrell Dow Pharmaceuticals | Tricyclic lactams active as antihypertensive agents |
CA1337654C (en) * | 1986-06-13 | 1995-11-28 | Gary A. Flynn | Fused tricyclic lactams as antihypertensive agents |
GB8629875D0 (en) * | 1986-12-15 | 1987-01-28 | Hoffmann La Roche | Pyridazodiazepine derivatives |
US4824832A (en) * | 1987-12-30 | 1989-04-25 | Merrell Dow Pharmaceuticals Inc. | Sulfhydryl containing tricyclic lactams and their pharmacological methods of use |
US5061694A (en) * | 1989-10-23 | 1991-10-29 | E. R. Squibb & Sons, Inc. | Method for stabilizing or causing regression of atherosclerosis in coronary arteries employing an ace inhibitor |
GB8926512D0 (en) * | 1989-11-23 | 1990-01-10 | Pfizer Ltd | Therapeutic agents |
WO1991009840A1 (en) * | 1989-12-22 | 1991-07-11 | Schering Corporation | Mercaptocycloacyl aminoacid endopeptidase inhibitors |
CA2053340C (en) * | 1990-10-18 | 2002-04-02 | Timothy P. Burkholder | Mercaptoacetylamide derivatives useful as inhibitors of enkephalinase and ace |
US5208230A (en) * | 1990-12-21 | 1993-05-04 | Merrell Dow Pharmaceuticals | Amino and nitro containing tricyclic compounds useful as inhibitors of ACE |
NZ241023A (en) * | 1990-12-21 | 1994-10-26 | Merrell Dow Pharma | Condensed benzazepine derivatives and pharmaceutical compositions |
FR2679564A1 (fr) * | 1991-07-23 | 1993-01-29 | Inst Nat Sante Rech Med | Nouveaux acylmercaptoalcanoldipeptides, leur preparation et les compositions qui les contiennent. |
AU2650692A (en) * | 1991-09-16 | 1993-04-27 | Schering Corporation | Pharmaceutical compositions comprising natriuretic peptides or neutral endopeptidase inhibitors for treating or preventing myointimal proliferation |
RU2124503C1 (ru) * | 1992-05-18 | 1999-01-10 | И.Р.Сквибб энд Санз, Инк. | Гетероциклические азотсодержащие производные карбоновой кислоты, способ их получения и фармацевтическая композиция |
US5238932A (en) * | 1992-05-20 | 1993-08-24 | Merrell Dow Pharmaceuticals Inc. | Mercaptoacetylamide tricyclic derivatives useful as inhibitors of enkephalinase |
-
1994
- 1994-03-24 US US08/217,781 patent/US5484783A/en not_active Expired - Lifetime
-
1995
- 1995-02-28 PT PT95913501T patent/PT751775E/pt unknown
- 1995-02-28 DK DK95913501T patent/DK0751775T3/da active
- 1995-02-28 AT AT95913501T patent/ATE217527T1/de active
- 1995-02-28 WO PCT/US1995/002476 patent/WO1995025548A2/en active IP Right Grant
- 1995-02-28 JP JP7523719A patent/JPH09510220A/ja active Pending
- 1995-02-28 KR KR1019960705294A patent/KR970701550A/ko not_active Application Discontinuation
- 1995-02-28 NZ NZ282949A patent/NZ282949A/en not_active IP Right Cessation
- 1995-02-28 ES ES95913501T patent/ES2173180T3/es not_active Expired - Lifetime
- 1995-02-28 EP EP95913501A patent/EP0751775B1/en not_active Expired - Lifetime
- 1995-02-28 DE DE69526731T patent/DE69526731T2/de not_active Expired - Lifetime
- 1995-02-28 AU AU20914/95A patent/AU705029B2/en not_active Ceased
- 1995-02-28 HU HU9602603A patent/HU226643B1/hu not_active IP Right Cessation
- 1995-02-28 CA CA002184693A patent/CA2184693C/en not_active Expired - Fee Related
- 1995-02-28 CN CN95192242A patent/CN1144483A/zh active Pending
- 1995-03-20 ZA ZA952285A patent/ZA952285B/xx unknown
- 1995-03-21 TW TW084102716A patent/TW323954B/zh not_active IP Right Cessation
- 1995-03-22 IL IL11307495A patent/IL113074A/xx not_active IP Right Cessation
-
1996
- 1996-09-23 FI FI963785A patent/FI118414B/fi not_active IP Right Cessation
- 1996-09-23 NO NO19963989A patent/NO313176B1/no not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
PT751775E (pt) | 2002-10-31 |
AU2091495A (en) | 1995-10-09 |
CA2184693C (en) | 2001-01-02 |
KR970701550A (ko) | 1997-04-12 |
WO1995025548A3 (en) | 1995-11-09 |
TW323954B (en) | 1998-01-01 |
US5484783A (en) | 1996-01-16 |
DE69526731D1 (en) | 2002-06-20 |
CA2184693A1 (en) | 1995-09-28 |
NO963989L (no) | 1996-11-22 |
ES2173180T3 (es) | 2002-10-16 |
FI963785A (fi) | 1996-09-23 |
FI118414B (fi) | 2007-11-15 |
HU226643B1 (en) | 2009-05-28 |
ZA952285B (en) | 1996-01-09 |
EP0751775B1 (en) | 2002-05-15 |
CN1144483A (zh) | 1997-03-05 |
FI963785A0 (fi) | 1996-09-23 |
HU9602603D0 (en) | 1996-11-28 |
NO313176B1 (no) | 2002-08-26 |
AU705029B2 (en) | 1999-05-13 |
JPH09510220A (ja) | 1997-10-14 |
DE69526731T2 (de) | 2003-02-06 |
IL113074A (en) | 2000-07-26 |
NZ282949A (en) | 1997-07-27 |
ATE217527T1 (de) | 2002-06-15 |
IL113074A0 (en) | 1995-06-29 |
WO1995025548A2 (en) | 1995-09-28 |
HUT74886A (en) | 1997-02-28 |
EP0751775A1 (en) | 1997-01-08 |
NO963989D0 (no) | 1996-09-23 |
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