NO307051B1 - 3-alkoksy-, fenoksy- eller benzyloksybenzo[b]tiofen-2- karboksamider som hemmere av celleadhesjon - Google Patents
3-alkoksy-, fenoksy- eller benzyloksybenzo[b]tiofen-2- karboksamider som hemmere av celleadhesjonInfo
- Publication number
- NO307051B1 NO307051B1 NO943126A NO943126A NO307051B1 NO 307051 B1 NO307051 B1 NO 307051B1 NO 943126 A NO943126 A NO 943126A NO 943126 A NO943126 A NO 943126A NO 307051 B1 NO307051 B1 NO 307051B1
- Authority
- NO
- Norway
- Prior art keywords
- carboxamides
- benzyloxybenzo
- thiophene
- phenoxy
- inhibitors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D333/70—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/840,361 US5208253A (en) | 1992-02-24 | 1992-02-24 | 3-alkyloxy-, aryloxy-, or arylalkyloxy-benzo(b) thiophene-2-carboxamides as inhibitors of cell adhesion |
| US08/015,005 US5356926A (en) | 1992-02-24 | 1993-02-09 | 3-alkyloxy-, aryloxy-, or arylalkyloxy-benzo [β]thiophene-2-carboxamides as inhibitors of cell adhesion |
| PCT/US1993/001672 WO1993017008A1 (en) | 1992-02-24 | 1993-02-23 | 3-ALKYLOXY-, ARYLOXY-, OR ARYLALKYLOXYBENZO[b]THIOPHENE-2-CARBOXAMIDES AS INHIBITORS OF CELL ADHESION |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO943126L NO943126L (no) | 1994-08-24 |
| NO943126D0 NO943126D0 (no) | 1994-08-24 |
| NO307051B1 true NO307051B1 (no) | 2000-01-31 |
Family
ID=26686829
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO943126A NO307051B1 (no) | 1992-02-24 | 1994-08-24 | 3-alkoksy-, fenoksy- eller benzyloksybenzo[b]tiofen-2- karboksamider som hemmere av celleadhesjon |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US5356926A (ja) |
| EP (2) | EP0628038B1 (ja) |
| JP (1) | JP3329460B2 (ja) |
| AT (2) | ATE182890T1 (ja) |
| AU (1) | AU665631B2 (ja) |
| CA (1) | CA2128701A1 (ja) |
| CZ (1) | CZ290968B6 (ja) |
| DE (2) | DE69332961T2 (ja) |
| DK (2) | DK0916666T3 (ja) |
| ES (2) | ES2198639T3 (ja) |
| FI (1) | FI943850A (ja) |
| GR (1) | GR3031095T3 (ja) |
| HU (1) | HUT68655A (ja) |
| NO (1) | NO307051B1 (ja) |
| NZ (1) | NZ249756A (ja) |
| PT (1) | PT916666E (ja) |
| RU (1) | RU2117665C1 (ja) |
| WO (1) | WO1993017008A1 (ja) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4317076A1 (de) * | 1993-05-21 | 1994-11-24 | Bayer Ag | Benzthiophencarbonsäureamid-S-oxide |
| US5484808A (en) * | 1995-02-09 | 1996-01-16 | Eli Lilly And Company | Methods of inhibiting cell-cell adhesion |
| DE19642451A1 (de) * | 1996-10-15 | 1998-04-16 | Merck Patent Gmbh | Aminothiophencarbonsäureamide |
| PL191760B1 (pl) * | 1996-12-13 | 2006-06-30 | Shionogi & Co | Związki, pochodne benzotiofenokarboksyamidu, związki pośrednie, kompozycja farmaceutyczna zawierająca te pochodne oraz lek do leczenia blokady nosa |
| FR2777886B1 (fr) * | 1998-04-27 | 2002-05-31 | Adir | Nouveaux derives benzothiopheniques, benzofuraniques et indoliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| EP1310488A4 (en) | 2000-08-09 | 2005-08-10 | Mitsubishi Pharma Corp | CONDENSED BICYCLIC AMIDE COMPOUNDS AND MEDICAL USES THEREOF |
| AR037097A1 (es) | 2001-10-05 | 2004-10-20 | Novartis Ag | Compuestos acilsulfonamidas, composiciones farmaceuticas y el uso de dichos compuestos para la preparacion de un medicamento |
| JP2005194192A (ja) * | 2002-01-11 | 2005-07-21 | Meiji Seika Kaisha Ltd | （４−オキソピペリジン−１−イル）安息香酸誘導体およびこれを用いたインテグリンαｖβ３阻害剤の製造法 |
| US7674822B2 (en) * | 2004-11-24 | 2010-03-09 | Wyeth | PTP1b inhibitors |
| WO2006101454A1 (en) * | 2005-03-21 | 2006-09-28 | S*Bio Pte Ltd | Benzothiophene derivatives: preparation and pharmaceutical applications |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4703053A (en) * | 1985-10-28 | 1987-10-27 | Warner-Lambert Company | Benzothiophenes and benzofurans and antiallergic use thereof |
| US4761424A (en) * | 1985-10-01 | 1988-08-02 | Warner-Lambert Company | Enolamides, pharmaceutical compositions and methods for treating inflammation |
| US4800211A (en) * | 1986-08-18 | 1989-01-24 | Merck & Co., Inc. | 5-methylthio-3-hydroxybenzo [b]thiophene-2-carboxamide derivatives as cyclooxygenase and lipoxygenase inhibitors |
| DE3832848A1 (de) * | 1988-09-28 | 1990-03-29 | Bayer Ag | Benzothiophen-2-carboxamid-s,s-dioxide |
| DE3832846A1 (de) * | 1988-09-28 | 1990-03-29 | Bayer Ag | Verwendung von benzothiophen-2-carboxamid-s,s-dioxiden zur behandlung von krankheiten |
| WO1995005170A1 (en) * | 1993-08-13 | 1995-02-23 | Warner-Lambert Company | Methods of inhibiting hiv and inhibiting the activation of hiv |
-
1993
- 1993-02-09 US US08/015,005 patent/US5356926A/en not_active Expired - Fee Related
- 1993-02-23 DK DK98123718T patent/DK0916666T3/da active
- 1993-02-23 DE DE69332961T patent/DE69332961T2/de not_active Expired - Fee Related
- 1993-02-23 WO PCT/US1993/001672 patent/WO1993017008A1/en active IP Right Grant
- 1993-02-23 DE DE69325899T patent/DE69325899T2/de not_active Expired - Fee Related
- 1993-02-23 CZ CZ19942017A patent/CZ290968B6/cs not_active IP Right Cessation
- 1993-02-23 NZ NZ249756A patent/NZ249756A/en unknown
- 1993-02-23 CA CA002128701A patent/CA2128701A1/en not_active Abandoned
- 1993-02-23 PT PT98123718T patent/PT916666E/pt unknown
- 1993-02-23 ES ES98123718T patent/ES2198639T3/es not_active Expired - Lifetime
- 1993-02-23 AT AT93906217T patent/ATE182890T1/de not_active IP Right Cessation
- 1993-02-23 DK DK93906217T patent/DK0628038T3/da active
- 1993-02-23 EP EP93906217A patent/EP0628038B1/en not_active Expired - Lifetime
- 1993-02-23 AT AT98123718T patent/ATE239718T1/de not_active IP Right Cessation
- 1993-02-23 JP JP51506593A patent/JP3329460B2/ja not_active Expired - Fee Related
- 1993-02-23 RU RU94045150A patent/RU2117665C1/ru not_active IP Right Cessation
- 1993-02-23 EP EP98123718A patent/EP0916666B1/en not_active Expired - Lifetime
- 1993-02-23 AU AU37331/93A patent/AU665631B2/en not_active Ceased
- 1993-02-23 HU HU9402421A patent/HUT68655A/hu unknown
- 1993-02-23 ES ES93906217T patent/ES2137253T3/es not_active Expired - Lifetime
-
1994
- 1994-08-22 FI FI943850A patent/FI943850A/fi not_active IP Right Cessation
- 1994-08-24 NO NO943126A patent/NO307051B1/no not_active IP Right Cessation
-
1999
- 1999-08-26 GR GR990402178T patent/GR3031095T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GR3031095T3 (en) | 1999-12-31 |
| EP0916666A1 (en) | 1999-05-19 |
| EP0916666B1 (en) | 2003-05-07 |
| FI943850A0 (fi) | 1994-08-22 |
| ES2137253T3 (es) | 1999-12-16 |
| AU3733193A (en) | 1993-09-13 |
| ATE182890T1 (de) | 1999-08-15 |
| EP0628038A1 (en) | 1994-12-14 |
| US5356926A (en) | 1994-10-18 |
| DE69325899T2 (de) | 2000-02-24 |
| JP3329460B2 (ja) | 2002-09-30 |
| WO1993017008A1 (en) | 1993-09-02 |
| NO943126L (no) | 1994-08-24 |
| DK0628038T3 (da) | 2000-02-28 |
| AU665631B2 (en) | 1996-01-11 |
| NO943126D0 (no) | 1994-08-24 |
| DE69332961T2 (de) | 2004-03-11 |
| FI943850A (fi) | 1994-10-19 |
| RU94045150A (ru) | 1996-08-10 |
| JPH07504199A (ja) | 1995-05-11 |
| ES2198639T3 (es) | 2004-02-01 |
| HU9402421D0 (en) | 1994-10-28 |
| DE69325899D1 (de) | 1999-09-09 |
| EP0628038B1 (en) | 1999-08-04 |
| ATE239718T1 (de) | 2003-05-15 |
| HUT68655A (en) | 1995-07-28 |
| NZ249756A (en) | 1996-05-28 |
| CZ9402017A3 (en) | 1995-04-12 |
| CZ290968B6 (cs) | 2002-11-13 |
| PT916666E (pt) | 2003-08-29 |
| DK0916666T3 (da) | 2003-09-01 |
| RU2117665C1 (ru) | 1998-08-20 |
| DE69332961D1 (de) | 2003-06-12 |
| CA2128701A1 (en) | 1993-09-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM1K | Lapsed by not paying the annual fees |