NO305535B1 - FremgangsmÕte for fremstilling av interdigitasjonfusjonsliposomer - Google Patents
FremgangsmÕte for fremstilling av interdigitasjonfusjonsliposomer Download PDFInfo
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- NO305535B1 NO305535B1 NO922735A NO922735A NO305535B1 NO 305535 B1 NO305535 B1 NO 305535B1 NO 922735 A NO922735 A NO 922735A NO 922735 A NO922735 A NO 922735A NO 305535 B1 NO305535 B1 NO 305535B1
- Authority
- NO
- Norway
- Prior art keywords
- liposomes
- lipid
- bioactive agent
- interdigitation
- gel
- Prior art date
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- 239000003193 general anesthetic agent Substances 0.000 description 1
- 238000007429 general method Methods 0.000 description 1
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- GDOPTJXRTPNYNR-UHFFFAOYSA-N methyl-cyclopentane Natural products CC1CCCC1 GDOPTJXRTPNYNR-UHFFFAOYSA-N 0.000 description 1
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- 239000011707 mineral Substances 0.000 description 1
- 239000003068 molecular probe Substances 0.000 description 1
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- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 description 1
- 230000005298 paramagnetic effect Effects 0.000 description 1
- 238000007911 parenteral administration Methods 0.000 description 1
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- 229920001184 polypeptide Polymers 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
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- 229930002330 retinoic acid Natural products 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- PYWVYCXTNDRMGF-UHFFFAOYSA-N rhodamine B Chemical group [Cl-].C=12C=CC(=[N+](CC)CC)C=C2OC2=CC(N(CC)CC)=CC=C2C=1C1=CC=CC=C1C(O)=O PYWVYCXTNDRMGF-UHFFFAOYSA-N 0.000 description 1
- 229960004889 salicylic acid Drugs 0.000 description 1
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- 238000000926 separation method Methods 0.000 description 1
- 238000004513 sizing Methods 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- PXLIDIMHPNPGMH-UHFFFAOYSA-N sodium chromate Chemical compound [Na+].[Na+].[O-][Cr]([O-])(=O)=O PXLIDIMHPNPGMH-UHFFFAOYSA-N 0.000 description 1
- 239000001509 sodium citrate Substances 0.000 description 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
- 238000002798 spectrophotometry method Methods 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
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- 230000001975 sympathomimetic effect Effects 0.000 description 1
- 229940064707 sympathomimetics Drugs 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 239000006188 syrup Substances 0.000 description 1
- 235000020357 syrup Nutrition 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- NLVFBUXFDBBNBW-PBSUHMDJSA-N tobramycin Chemical compound N[C@@H]1C[C@H](O)[C@@H](CN)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](N)[C@H](O)[C@@H](CO)O2)O)[C@H](N)C[C@@H]1N NLVFBUXFDBBNBW-PBSUHMDJSA-N 0.000 description 1
- 229960000707 tobramycin Drugs 0.000 description 1
- 235000010384 tocopherol Nutrition 0.000 description 1
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- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1277—Processes for preparing; Proliposomes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Dispersion Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US46452890A | 1990-01-12 | 1990-01-12 | |
| PCT/US1991/000259 WO1991010422A1 (en) | 1990-01-12 | 1991-01-11 | Interdigitation-fusion liposomes and gels |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO922735D0 NO922735D0 (no) | 1992-07-10 |
| NO922735L NO922735L (no) | 1992-08-12 |
| NO305535B1 true NO305535B1 (no) | 1999-06-21 |
Family
ID=23844291
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO922735A NO305535B1 (no) | 1990-01-12 | 1992-07-10 | FremgangsmÕte for fremstilling av interdigitasjonfusjonsliposomer |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP0510086B1 (de) |
| JP (1) | JP3131923B2 (de) |
| KR (1) | KR920703015A (de) |
| AT (1) | ATE146074T1 (de) |
| AU (1) | AU652552B2 (de) |
| CA (1) | CA2073431C (de) |
| DE (1) | DE69123568T2 (de) |
| DK (1) | DK0510086T3 (de) |
| ES (1) | ES2096646T3 (de) |
| GR (1) | GR3022701T3 (de) |
| HK (1) | HK1007499A1 (de) |
| IE (1) | IE910086A1 (de) |
| NO (1) | NO305535B1 (de) |
| PT (1) | PT96465B (de) |
| WO (1) | WO1991010422A1 (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5882678A (en) * | 1990-01-12 | 1999-03-16 | The Liposome Co, Inc. | Interdigitation-fusion liposomes containing arachidonic acid metabolites |
| US5820848A (en) * | 1990-01-12 | 1998-10-13 | The Liposome Company, Inc. | Methods of preparing interdigitation-fusion liposomes and gels which encapsulate a bioactive agent |
| US6623671B2 (en) | 1990-10-05 | 2003-09-23 | Royden M. Coe | Liposome extrusion process |
| WO1992005772A1 (en) * | 1990-10-05 | 1992-04-16 | The Liposome Company, Inc. | Liposome extrusion process |
| IT1255476B (it) * | 1992-07-30 | 1995-11-02 | Glicerofosfoderivati farmacologicamente attivi | |
| MX9306373A (es) * | 1992-10-14 | 1994-06-30 | Liposome Co Inc | Liposomas y geles de fusion por interdigitacion. |
| WO1995013797A1 (en) * | 1993-11-16 | 1995-05-26 | The Liposome Company, Inc. | Interdigitation-fusion liposomes containing arachidonic acid metabolites |
| US5716526A (en) * | 1994-01-14 | 1998-02-10 | The Liposome Company, Inc. | Method of separating materials from liposomes or lipid complexes |
| CN1148812A (zh) * | 1994-03-28 | 1997-04-30 | 尼科梅德成像有限公司 | “脂质体” |
| WO1996016980A1 (en) * | 1994-11-29 | 1996-06-06 | Novartis Ag | Morpholinoethylamide derivatives |
| US6613352B2 (en) | 1999-04-13 | 2003-09-02 | Universite De Montreal | Low-rigidity liposomal formulation |
| GR20180100082A (el) * | 2018-02-28 | 2019-09-25 | ΝΙΚΟΛΑΟΣ Α. ΦΙΚΙΩΡΗΣ ΚΑΙ ΣΙΑ ΕΤΑΙΡΕΙΑ ΠΕΡΙΟΡΙΣΜΕΝΗΣ ΕΥΘΗΝΗΣ με δ.τ. IN TOUCH HEALTH Ε.Π.Ε | Μεθοδος για την παραγωγη οχηματων μεταφορας λιπιδιων |
| CN111387339B (zh) * | 2020-02-20 | 2022-11-25 | 浙江工商大学 | 一种具有仿母乳脂肪球结构的大尺寸脂质体及其制备方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4515736A (en) * | 1983-05-12 | 1985-05-07 | The Regents Of The University Of California | Method for encapsulating materials into liposomes |
| JPS59218956A (ja) * | 1983-05-27 | 1984-12-10 | Fujirebio Inc | 膜融合測定方法 |
| US4544545A (en) * | 1983-06-20 | 1985-10-01 | Trustees University Of Massachusetts | Liposomes containing modified cholesterol for organ targeting |
| US4789633A (en) * | 1984-04-19 | 1988-12-06 | University Of Tennessee Research Corporation | Fused liposome and acid induced method for liposome fusion |
| US4921706A (en) * | 1984-11-20 | 1990-05-01 | Massachusetts Institute Of Technology | Unilamellar lipid vesicles and method for their formation |
| JPH0751496B2 (ja) * | 1986-04-02 | 1995-06-05 | 武田薬品工業株式会社 | リポソ−ムの製造法 |
| US4962022A (en) * | 1986-09-22 | 1990-10-09 | Becton Dickinson And Company | Storage and use of liposomes |
| US4944948A (en) * | 1989-02-24 | 1990-07-31 | Liposome Technology, Inc. | EGF/Liposome gel composition and method |
-
1991
- 1991-01-11 ES ES91903087T patent/ES2096646T3/es not_active Expired - Lifetime
- 1991-01-11 WO PCT/US1991/000259 patent/WO1991010422A1/en active IP Right Grant
- 1991-01-11 DE DE69123568T patent/DE69123568T2/de not_active Expired - Fee Related
- 1991-01-11 CA CA002073431A patent/CA2073431C/en not_active Expired - Fee Related
- 1991-01-11 KR KR1019920701613A patent/KR920703015A/ko not_active Application Discontinuation
- 1991-01-11 AU AU71817/91A patent/AU652552B2/en not_active Ceased
- 1991-01-11 DK DK91903087.4T patent/DK0510086T3/da active
- 1991-01-11 EP EP91903087A patent/EP0510086B1/de not_active Expired - Lifetime
- 1991-01-11 IE IE008691A patent/IE910086A1/en not_active IP Right Cessation
- 1991-01-11 PT PT96465A patent/PT96465B/pt not_active IP Right Cessation
- 1991-01-11 AT AT91903087T patent/ATE146074T1/de not_active IP Right Cessation
- 1991-01-11 JP JP03503398A patent/JP3131923B2/ja not_active Expired - Fee Related
-
1992
- 1992-07-10 NO NO922735A patent/NO305535B1/no unknown
-
1997
- 1997-02-27 GR GR970400387T patent/GR3022701T3/el unknown
-
1998
- 1998-06-25 HK HK98106750A patent/HK1007499A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| GR3022701T3 (en) | 1997-05-31 |
| DK0510086T3 (da) | 1997-06-09 |
| WO1991010422A1 (en) | 1991-07-25 |
| CA2073431C (en) | 1999-05-25 |
| AU652552B2 (en) | 1994-09-01 |
| EP0510086A4 (en) | 1993-03-17 |
| ES2096646T3 (es) | 1997-03-16 |
| DE69123568T2 (de) | 1997-05-28 |
| ATE146074T1 (de) | 1996-12-15 |
| EP0510086B1 (de) | 1996-12-11 |
| PT96465A (pt) | 1991-10-15 |
| CA2073431A1 (en) | 1991-07-13 |
| JPH05503521A (ja) | 1993-06-10 |
| KR920703015A (ko) | 1992-12-17 |
| DE69123568D1 (de) | 1997-01-23 |
| PT96465B (pt) | 1998-06-30 |
| EP0510086A1 (de) | 1992-10-28 |
| HK1007499A1 (en) | 1999-04-16 |
| AU7181791A (en) | 1991-08-05 |
| NO922735D0 (no) | 1992-07-10 |
| JP3131923B2 (ja) | 2001-02-05 |
| IE910086A1 (en) | 1991-07-17 |
| NO922735L (no) | 1992-08-12 |
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