NO305223B1 - Farmas°ytiske preparater med langsom frigivelse inneholdende nifedipin og fremgangsmÕte for fremstilling derav - Google Patents

Farmas°ytiske preparater med langsom frigivelse inneholdende nifedipin og fremgangsmÕte for fremstilling derav

Info

Publication number
NO305223B1
NO305223B1 NO942622A NO942622A NO305223B1 NO 305223 B1 NO305223 B1 NO 305223B1 NO 942622 A NO942622 A NO 942622A NO 942622 A NO942622 A NO 942622A NO 305223 B1 NO305223 B1 NO 305223B1
Authority
NO
Norway
Prior art keywords
pct
nifedipine
slow release
preparation
preparations containing
Prior art date
Application number
NO942622A
Other languages
English (en)
Norwegian (no)
Other versions
NO942622L (no
NO942622D0 (no
Inventor
David Trigger
Original Assignee
Ethical Pharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ethical Pharma Ltd filed Critical Ethical Pharma Ltd
Publication of NO942622L publication Critical patent/NO942622L/no
Publication of NO942622D0 publication Critical patent/NO942622D0/no
Publication of NO305223B1 publication Critical patent/NO305223B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Hydrogenated Pyridines (AREA)
  • Saccharide Compounds (AREA)
NO942622A 1992-01-13 1994-07-12 Farmas°ytiske preparater med langsom frigivelse inneholdende nifedipin og fremgangsmÕte for fremstilling derav NO305223B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929200607A GB9200607D0 (en) 1992-01-13 1992-01-13 Pharmaceutical compositions containing nifedipine and process for the preparation thereof
PCT/GB1993/000055 WO1993013773A1 (en) 1992-01-13 1993-01-12 Pharmaceutical compositions containing nifedipine and process for the preparation thereof

Publications (3)

Publication Number Publication Date
NO942622L NO942622L (no) 1994-07-12
NO942622D0 NO942622D0 (no) 1994-07-12
NO305223B1 true NO305223B1 (no) 1999-04-26

Family

ID=10708487

Family Applications (1)

Application Number Title Priority Date Filing Date
NO942622A NO305223B1 (no) 1992-01-13 1994-07-12 Farmas°ytiske preparater med langsom frigivelse inneholdende nifedipin og fremgangsmÕte for fremstilling derav

Country Status (24)

Country Link
US (1) US5594013A (ru)
EP (1) EP0620733B1 (ru)
JP (1) JPH07503003A (ru)
AT (1) ATE191144T1 (ru)
AU (1) AU659529B2 (ru)
CA (1) CA2126864A1 (ru)
DE (2) DE69328245T2 (ru)
DK (2) DK0620733T3 (ru)
ES (1) ES2146227T3 (ru)
FI (1) FI943316A (ru)
GB (2) GB9200607D0 (ru)
HU (2) HU219338B (ru)
IS (1) IS1620B (ru)
MY (1) MY110660A (ru)
NL (1) NL9320021A (ru)
NO (1) NO305223B1 (ru)
NZ (1) NZ246374A (ru)
PH (1) PH30985A (ru)
PL (1) PL170935B1 (ru)
PT (1) PT620733E (ru)
RU (1) RU2106139C1 (ru)
SE (1) SE9402457L (ru)
WO (1) WO1993013773A1 (ru)
ZA (1) ZA93195B (ru)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994005262A1 (en) * 1992-09-10 1994-03-17 F.H. Faulding & Co. Limited Sustained release matrix composition
US5455046A (en) * 1993-09-09 1995-10-03 Edward Mendell Co., Inc. Sustained release heterodisperse hydrogel systems for insoluble drugs
US5773025A (en) * 1993-09-09 1998-06-30 Edward Mendell Co., Inc. Sustained release heterodisperse hydrogel systems--amorphous drugs
US5871776A (en) * 1995-01-31 1999-02-16 Mehta; Atul M. Controlled-release nifedipine
WO1997008950A1 (en) * 1995-09-07 1997-03-13 Fuisz Technologies, Ltd. System for rendering substantially non-dissoluble bio-affecting agents bio-available
CO4771151A1 (es) * 1996-01-19 1999-04-30 Rachitzky Falicman Pablo Alberto Procedimiento para la elaboracion de una preparacion farmace utica que contiene nifedipina y la preparacion farmaceutica obtenida mediante el mismo
AU695734B2 (en) 1996-07-08 1998-08-20 Penwest Pharmaceuticals Co. Sustained release matrix for high-dose insoluble drugs
IT1284604B1 (it) * 1996-09-27 1998-05-21 Roberto Valducci Composizioni farmaceutiche a rilascio controllato per somministrazione orale contenenti nifedipina come sostanza attiva
US5922352A (en) * 1997-01-31 1999-07-13 Andrx Pharmaceuticals, Inc. Once daily calcium channel blocker tablet having a delayed release core
US5837379A (en) * 1997-01-31 1998-11-17 Andrx Pharmaceuticals, Inc. Once daily pharmaceutical tablet having a unitary core
US6056977A (en) 1997-10-15 2000-05-02 Edward Mendell Co., Inc. Once-a-day controlled release sulfonylurea formulation
US6485748B1 (en) 1997-12-12 2002-11-26 Andrx Pharmaceuticals, Inc. Once daily pharmaceutical tablet having a unitary core
US6264872B1 (en) 1997-12-30 2001-07-24 Kimberly-Clark Worldwide, Inc. Method of forming thin, embossed, textured barrier films
US6969529B2 (en) 2000-09-21 2005-11-29 Elan Pharma International Ltd. Nanoparticulate compositions comprising copolymers of vinyl pyrrolidone and vinyl acetate as surface stabilizers
US6706283B1 (en) 1999-02-10 2004-03-16 Pfizer Inc Controlled release by extrusion of solid amorphous dispersions of drugs
US6168806B1 (en) 1999-03-05 2001-01-02 Fang-Yu Lee Orally administrable nifedipine pellet and process for the preparation thereof
ATE419834T1 (de) * 2000-11-20 2009-01-15 Elan Pharma Int Ltd Nanopartikel bestehend aus einem arzneistoff und copolymeren von vinyl pyrrolidon und vinyl acetat als oberflächenstabilisatoren
SE0100200D0 (sv) * 2001-01-24 2001-01-24 Astrazeneca Ab New film coating
DE20220902U1 (de) * 2001-12-19 2004-06-09 Astrazeneca Ab Neuer Filmüberzug
US6620900B2 (en) * 2002-02-07 2003-09-16 Isp Investments Inc. Proliferous copolymer of vinyl pyrrolidone and vinyl acetate
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
US20070078513A1 (en) * 2002-09-18 2007-04-05 Medtronic Vascular, Inc. Controllable drug releasing gradient coatings for medical devices
JP2008535837A (ja) 2005-04-06 2008-09-04 マリンクロッド・インコーポレイテッド マトリックスをベースとするパルス放出製剤
WO2007106111A2 (en) * 2005-07-01 2007-09-20 Elan Pharma International Limited Nanoparticulate and controlled release compositions comprising nilvadipine
WO2009054550A1 (en) * 2007-10-25 2009-04-30 Bayer Yakuhin, Ltd. Nifedipine-containing press coated tablet and method of preparing the same
RU2629843C1 (ru) * 2016-05-24 2017-09-04 федеральное государственное автономное образовательное учреждение высшего образования Первый Московский государственный медицинский университет имени И.М. Сеченова Министерства здравоохранения Российской Федерации (Сеченовский университет) Способ получения мази нифедипина (варианты)

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2400819C2 (de) * 1974-01-09 1982-04-22 Bayer Ag, 5090 Leverkusen Verfahren zur Herstellung fester Zubereitungen von schwerlöslichen Arzneimittelwirkstoffen in feinster Verteilung
GB1579818A (en) * 1977-06-07 1980-11-26 Yamanouchi Pharma Co Ltd Nifedipine-containing solid preparation composition
EP0001247A1 (en) * 1977-09-14 1979-04-04 Kanebo, Ltd. Pharmaceutical preparation containing nifedipine and a method for producing the same.
CA1146866A (en) * 1979-07-05 1983-05-24 Yamanouchi Pharmaceutical Co. Ltd. Process for the production of sustained release pharmaceutical composition of solid medical material
EP0047894B2 (en) * 1980-09-05 1990-09-05 Argus Chemical Corporation Homogeneous storage-stable liquid barium-cadmium-triphosphite stabilizer systems for polyvinyl chloride resins
DE3033919A1 (de) * 1980-09-09 1982-04-22 Bayer Ag, 5090 Leverkusen Feste arzneizubereitungen enthaltend nifedipin und verfahren zu ihrer herstellung
JPS5846019A (ja) * 1981-09-14 1983-03-17 Kanebo Ltd 持続性ニフエジピン製剤
EP0078430B2 (de) * 1981-10-29 1993-02-10 Bayer Ag Verfahren zur Herstellung von festen, schnellfreisetzenden Arzneizubereitungen mit Dihydropyridinen
DE3580384D1 (de) * 1984-04-09 1990-12-13 Toyo Boseki Praeparat mit verzoegerter freigabe zum aufbringen auf die schleimhaeute der mundhoehle.
DE3424553A1 (de) * 1984-07-04 1986-01-09 Bayer Ag, 5090 Leverkusen Feste arzneizubereitungen mit dihydropyridinen und verfahren zu ihrer herstellung
IT1178511B (it) * 1984-09-14 1987-09-09 Pharmatec Spa Procedimento per la preparazione di una forma solida per uso orale a base di nifedipina con rilascio
DE3438830A1 (de) * 1984-10-23 1986-04-30 Rentschler Arzneimittel Nifedipin enthaltende darreichungsform und verfahren zu ihrer herstellung
FR2579510B1 (fr) * 1985-03-29 1989-12-15 Demler Sa Ets Table vibrante pour la fabrication de produits en beton
FR2585174B1 (fr) * 1985-07-16 1987-11-27 Eurofarad Procede de fabrication d'un composant capacitif multicouche a dielectrique ceramique du type cordierite, et composant ainsi obtenu
IE63321B1 (en) * 1986-02-03 1995-04-05 Elan Corp Plc Drug delivery system
SE8601624D0 (sv) * 1986-04-11 1986-04-11 Haessle Ab New pharmaceutical preparations
GB8613689D0 (en) * 1986-06-05 1986-07-09 Euro Celtique Sa Pharmaceutical composition
US4970075A (en) * 1986-07-18 1990-11-13 Euroceltique, S.A. Controlled release bases for pharmaceuticals
IE59540B1 (en) * 1987-01-09 1994-03-09 Elan Corp Sustained release capsule or tablet formulation
US4968508A (en) * 1987-02-27 1990-11-06 Eli Lilly And Company Sustained release matrix
GB8722306D0 (en) * 1987-09-22 1987-10-28 Aps Research Ltd Sustained-release formulation
GB8903328D0 (en) * 1989-02-14 1989-04-05 Ethical Pharma Ltd Nifedipine-containing pharmaceutical compositions and process for the preparation thereof
ES2077023T3 (es) * 1989-03-10 1995-11-16 Yamanouchi Pharma Co Ltd Material de recubrimiento que controla la liberacion de un medicamento para formulaciones de actividad prolongada.
HU203041B (en) * 1989-03-14 1991-05-28 Egyt Gyogyszervegyeszeti Gyar Process for producing pharmaceutical compositions of controlled releasing factor containing nifedipin
JPH0729926B2 (ja) * 1989-07-25 1995-04-05 大塚製薬株式会社 易吸収性製剤用組成物

Also Published As

Publication number Publication date
WO1993013773A1 (en) 1993-07-22
JPH07503003A (ja) 1995-03-30
NL9320021A (nl) 1995-06-01
GB2277872A (en) 1994-11-16
HU219338B (en) 2001-03-28
ES2146227T3 (es) 2000-08-01
FI943316A0 (fi) 1994-07-12
DE4390075T1 (de) 1994-12-01
FI943316A (fi) 1994-07-12
SE9402457D0 (sv) 1994-07-12
NO942622L (no) 1994-07-12
EP0620733B1 (en) 2000-03-29
DK0620733T3 (da) 2000-07-24
SE9402457L (sv) 1994-09-12
AU659529B2 (en) 1995-05-18
CA2126864A1 (en) 1993-07-22
RU2106139C1 (ru) 1998-03-10
HU9401850D0 (en) 1994-09-28
GB2277872B (en) 1995-10-04
PL170935B1 (pl) 1997-02-28
IS1620B (is) 1996-10-18
EP0620733A1 (en) 1994-10-26
RU94035739A (ru) 1996-09-20
ZA93195B (en) 1993-08-16
NZ246374A (en) 1995-07-26
PT620733E (pt) 2000-08-31
AU3263693A (en) 1993-08-03
HUT67426A (en) 1995-04-28
DK83794A (da) 1994-07-11
US5594013A (en) 1997-01-14
DE69328245D1 (de) 2000-05-04
NO942622D0 (no) 1994-07-12
DE69328245T2 (de) 2000-10-12
GB9200607D0 (en) 1992-03-11
PL300638A1 (en) 1994-03-21
MY110660A (en) 1999-01-30
PH30985A (en) 1997-12-23
IS3966A (is) 1993-07-14
GB9413101D0 (en) 1994-08-31
HU210539A9 (en) 1995-05-29
ATE191144T1 (de) 2000-04-15

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