NO301577B1 - Fremgangsmåte for fremstilling av en stabil vaksineblanding og fremgangsmåte for stabilisering av interleukin i en vaksineblanding - Google Patents

Fremgangsmåte for fremstilling av en stabil vaksineblanding og fremgangsmåte for stabilisering av interleukin i en vaksineblanding Download PDF

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Publication number
NO301577B1
NO301577B1 NO920161A NO920161A NO301577B1 NO 301577 B1 NO301577 B1 NO 301577B1 NO 920161 A NO920161 A NO 920161A NO 920161 A NO920161 A NO 920161A NO 301577 B1 NO301577 B1 NO 301577B1
Authority
NO
Norway
Prior art keywords
interleukin
antigen
bacterial
rhil
alum
Prior art date
Application number
NO920161A
Other languages
English (en)
Norwegian (no)
Other versions
NO920161D0 (no
NO920161L (no
Inventor
Subramonia Pillai
Garvin Bixler
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of NO920161D0 publication Critical patent/NO920161D0/no
Publication of NO920161L publication Critical patent/NO920161L/no
Publication of NO301577B1 publication Critical patent/NO301577B1/no

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55522Cytokines; Lymphokines; Interferons
    • A61K2039/55527Interleukins

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO920161A 1989-07-14 1992-01-13 Fremgangsmåte for fremstilling av en stabil vaksineblanding og fremgangsmåte for stabilisering av interleukin i en vaksineblanding NO301577B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37974289A 1989-07-14 1989-07-14
PCT/US1990/003982 WO1991001143A1 (en) 1989-07-14 1990-07-16 Stable vaccine compositions containing interleukins

Publications (3)

Publication Number Publication Date
NO920161D0 NO920161D0 (no) 1992-01-13
NO920161L NO920161L (no) 1992-03-05
NO301577B1 true NO301577B1 (no) 1997-11-17

Family

ID=23498494

Family Applications (1)

Application Number Title Priority Date Filing Date
NO920161A NO301577B1 (no) 1989-07-14 1992-01-13 Fremgangsmåte for fremstilling av en stabil vaksineblanding og fremgangsmåte for stabilisering av interleukin i en vaksineblanding

Country Status (12)

Country Link
EP (1) EP0482076B1 (ko)
JP (2) JP3485184B2 (ko)
KR (1) KR0177179B1 (ko)
AT (1) ATE121629T1 (ko)
AU (1) AU648509B2 (ko)
CA (1) CA2063587C (ko)
DE (1) DE69018990T2 (ko)
DK (1) DK0482076T3 (ko)
ES (1) ES2075900T3 (ko)
FI (1) FI104233B1 (ko)
NO (1) NO301577B1 (ko)
WO (1) WO1991001143A1 (ko)

Families Citing this family (32)

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US6406696B1 (en) 1989-10-27 2002-06-18 Tolerance Therapeutics, Inc. Methods of stimulating the immune system with anti-CD3 antibodies
DE69032484D1 (de) * 1989-10-27 1998-08-20 Arch Dev Corp Zusammensetzungen und deren verwendung zur förderung der immunopotentiation
GR1000881B (el) * 1990-08-06 1993-03-16 Praxis Biolog Inc Σταθερες συνθεσεις εμβολιου που περιεχουν ιντερλευκινες.
AU9161591A (en) * 1990-12-19 1992-07-22 Schering Corporation Use of il-4 to enhance immune response to immunogens in vaccines
WO1992020370A1 (en) * 1991-05-13 1992-11-26 Regents Of The University Of California Liposomal polysaccharide vaccines
DE4126983A1 (de) 1991-08-15 1993-02-18 Boehringer Mannheim Gmbh Verfahren zur herstellung von humanprotein-enthaltenden, konservierten arzneimitteln fuer infusions- oder injektionszwecke
DE69310182T2 (de) * 1992-08-10 1997-12-04 Us Gov Health & Human Serv Interleukin-4 stimulierter t-lymphozyten-zelltod
ZA936095B (en) * 1992-08-21 1994-03-14 Univ Melbourne Cytokine applications.
US6491916B1 (en) 1994-06-01 2002-12-10 Tolerance Therapeutics, Inc. Methods and materials for modulation of the immunosuppresive activity and toxicity of monoclonal antibodies
WO1996007102A1 (en) * 1994-09-01 1996-03-07 Wisconsin Alumni Research Foundation Therapeutic remodeling in aids
US6509313B1 (en) 1996-02-28 2003-01-21 Cornell Research Foundation, Inc. Stimulation of immune response with low doses of cytokines
AU724743B2 (en) * 1996-05-31 2000-09-28 Genetics Institute, Llc IL-12 as an adjuvant for Bordetella Pertussis vaccines
TW586934B (en) * 1997-05-19 2004-05-11 Sumitomo Pharma Immunopotentiating composition
US6270758B1 (en) 1998-10-08 2001-08-07 Duke University Substantially non-toxic biologically active mucosal adjuvants in vertebrate subjects
US6027731A (en) * 1998-11-17 2000-02-22 Wisconsin Alumni Research Foundation Pertussis toxin induced lymphocytosis
IT1302534B1 (it) 1998-12-21 2000-09-05 Fidia Advanced Biopolymers Srl Composizioni iniettabili, biocompatibili e biodegradabili comprendentialmeno un derivato dell'acido ialuronico, cellule condrogeniche, per
SK782002A3 (en) * 1999-07-21 2003-08-05 Lexigen Pharm Corp FC fusion proteins for enhancing the immunogenicity of protein and peptide antigens
DE60040740D1 (de) 1999-12-03 2008-12-18 Celltech Chiroscience Ltd VERWENDUNG OF INTERLEUkIN-1 MUTEIN ALS IMPFSTOFFADJUVANS
EP2497496A3 (en) 2005-07-11 2013-02-20 Macrogenics, Inc. Methods for the treatment of autoimmune disorders using immunosuppressive monoclonal antibodies with reduced toxicity
JP2009510032A (ja) * 2005-09-30 2009-03-12 リポクセン テクノロジーズ リミテッド 多糖抗原及びタンパク質アジュバントを含む多価リポソームワクチン組成物
BRPI0713426A2 (pt) 2006-06-14 2012-10-09 Macrogenics Inc métodos de tratar, diminuir a progressão, ou melhorar um ou mais sintomas de um distúrbio, e de prevenir ou retardar o inìcio de um distúrbio
US7709010B2 (en) * 2007-03-09 2010-05-04 Merck Sharp & Dohme Corp. Papillomavirus vaccine compositions
ES2641375T3 (es) * 2012-11-02 2017-11-08 Cytuvax Composición que comprende macroagregados de citoquinas
JOP20190242A1 (ar) * 2018-10-12 2020-04-12 Serum Institute Of India Pvt Ltd تركيبة لقاح توليفي تشمل فيروس شلل الأطفال ذو جرعة مخفّضة خاملة التنشيط وطريقة لتحضيرها
CN113365650A (zh) 2018-11-16 2021-09-07 新免疫技术有限公司 用il-7蛋白和免疫检查点抑制剂的组合治疗肿瘤的方法
WO2021146191A1 (en) 2020-01-13 2021-07-22 Neoimmunetech, Inc. Method of treating a tumor with a combination of il-7 protein and a bispecific antibody
JP2023512657A (ja) 2020-02-05 2023-03-28 ワシントン・ユニバーシティ Il-7タンパク質とcar保有免疫細胞の組み合わせで固形腫瘍を治療する方法
US20230398184A1 (en) 2020-10-26 2023-12-14 Neoimmunetech, Inc. Methods of inducing stem cell mobilization
KR20230104176A (ko) 2020-11-02 2023-07-07 네오이뮨텍, 인코퍼레이티드 코로나바이러스의 치료를 위한 인터류킨-7의 용도
AU2021376396A1 (en) 2020-11-05 2023-06-08 Neoimmunetech, Inc. Method of treating a tumor with a combination of an il-7 protein and a nucleotide vaccine
WO2023130081A1 (en) 2021-12-30 2023-07-06 Neoimmunetech, Inc. Method of treating a tumor with a combination of il-7 protein and vegf antagonist
WO2024102722A1 (en) 2022-11-07 2024-05-16 Neoimmunetech, Inc. Methods of treating a tumor with an unmethylated mgmt promoter

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2849632B2 (ja) * 1988-04-08 1999-01-20 社団法人北里研究所 ワクチン製剤
DE3818054C2 (de) * 1988-05-27 1994-02-17 Biotest Pharma Gmbh Verwendung einer Kombination aus einem Antigen bzw. einer Vakzine und humanem Interleukin zur Behandlung der Non-Responsiveness gegenüber immunologischen Defektzuständen
JPH0236129A (ja) * 1988-07-22 1990-02-06 Ajinomoto Co Inc ワクチン効果増強剤

Also Published As

Publication number Publication date
KR0177179B1 (ko) 1999-03-20
EP0482076B1 (en) 1995-04-26
AU6050090A (en) 1991-02-22
FI104233B (fi) 1999-12-15
JP2004002463A (ja) 2004-01-08
ATE121629T1 (de) 1995-05-15
KR920703103A (ko) 1992-12-17
DK0482076T3 (da) 1995-07-17
EP0482076A1 (en) 1992-04-29
NO920161D0 (no) 1992-01-13
JP3485184B2 (ja) 2004-01-13
JPH04506663A (ja) 1992-11-19
WO1991001143A1 (en) 1991-02-07
FI920132A0 (fi) 1992-01-13
AU648509B2 (en) 1994-04-28
ES2075900T3 (es) 1995-10-16
FI104233B1 (fi) 1999-12-15
DE69018990D1 (de) 1995-06-01
NO920161L (no) 1992-03-05
DE69018990T2 (de) 1995-12-14
CA2063587A1 (en) 1991-01-15
CA2063587C (en) 2005-08-30

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