DE69032484D1 - Zusammensetzungen und deren verwendung zur förderung der immunopotentiation - Google Patents
Zusammensetzungen und deren verwendung zur förderung der immunopotentiationInfo
- Publication number
- DE69032484D1 DE69032484D1 DE69032484A DE69032484A DE69032484D1 DE 69032484 D1 DE69032484 D1 DE 69032484D1 DE 69032484 A DE69032484 A DE 69032484A DE 69032484 A DE69032484 A DE 69032484A DE 69032484 D1 DE69032484 D1 DE 69032484D1
- Authority
- DE
- Germany
- Prior art keywords
- protein
- agents
- cells
- heteroconjugate
- immunopotentiating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/085—Staphylococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/7051—T-cell receptor (TcR)-CD3 complex
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55516—Proteins; Peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55544—Bacterial toxins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6056—Antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
- C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US42972989A | 1989-10-27 | 1989-10-27 | |
US52430490A | 1990-05-16 | 1990-05-16 | |
PCT/US1990/006177 WO1991006319A1 (en) | 1989-10-27 | 1990-10-26 | Methods and compositions for promoting immunopotentiation |
Publications (1)
Publication Number | Publication Date |
---|---|
DE69032484D1 true DE69032484D1 (de) | 1998-08-20 |
Family
ID=27028317
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69032484T Expired - Lifetime DE69032484T4 (de) | 1989-10-27 | 1990-10-26 | Zusammensetzungen und deren verwendung zur förderung der immunopotentiation |
DE69032484A Expired - Fee Related DE69032484D1 (de) | 1989-10-27 | 1990-10-26 | Zusammensetzungen und deren verwendung zur förderung der immunopotentiation |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69032484T Expired - Lifetime DE69032484T4 (de) | 1989-10-27 | 1990-10-26 | Zusammensetzungen und deren verwendung zur förderung der immunopotentiation |
Country Status (8)
Country | Link |
---|---|
US (2) | US6113901A (de) |
EP (2) | EP0839536A1 (de) |
JP (1) | JP2546544B2 (de) |
AT (1) | ATE168272T1 (de) |
AU (1) | AU6642390A (de) |
CA (1) | CA2071478A1 (de) |
DE (2) | DE69032484T4 (de) |
WO (1) | WO1991006319A1 (de) |
Families Citing this family (65)
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US6685941B1 (en) | 1988-11-23 | 2004-02-03 | The Regents Of The University Of Michigan | Methods of treating autoimmune disease via CTLA-4Ig |
CA2071478A1 (en) * | 1989-10-27 | 1991-04-28 | Jeffery A. Bluestone | Methods and compositions for promoting immunopotentiation |
US6406696B1 (en) | 1989-10-27 | 2002-06-18 | Tolerance Therapeutics, Inc. | Methods of stimulating the immune system with anti-CD3 antibodies |
US5480895A (en) * | 1991-09-27 | 1996-01-02 | New York Society For The Relief Of The Ruptured And Crippled, Maintaining The Hospital For Special Surgery | Method of producing antibodies to a restricted population of T lymphocytes, antibodies produced therefrom and methods of use thereof |
US20030108548A1 (en) * | 1993-06-01 | 2003-06-12 | Bluestone Jeffrey A. | Methods and materials for modulation of the immunosuppressive activity and toxicity of monoclonal antibodies |
GB9607711D0 (en) * | 1996-04-13 | 1996-06-19 | Univ Sheffield | T-cell dependent vaccine |
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JP4776075B2 (ja) | 1998-12-31 | 2011-09-21 | ノバルティス バクシンズ アンド ダイアグノスティックス,インコーポレーテッド | 改変hivenvポリペプチド |
US6737398B1 (en) * | 1999-09-30 | 2004-05-18 | National Jewish Medical And Research Center | Modulation of γδ T cells to regulate airway hyperresponsiveness |
AU1084901A (en) | 1999-10-14 | 2001-04-23 | Martha S. Hayden-Ledbetter | Dna vaccines encoding antigen linked to a domain that binds cd40 |
US6867041B2 (en) * | 2000-02-24 | 2005-03-15 | Xcyte Therapies, Inc. | Simultaneous stimulation and concentration of cells |
US20030235908A1 (en) * | 2000-02-24 | 2003-12-25 | Xcyte Therapies, Inc. | Activation and expansion of cells |
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US20030119185A1 (en) * | 2000-02-24 | 2003-06-26 | Xcyte Therapies, Inc. | Activation and expansion of cells |
US6797514B2 (en) * | 2000-02-24 | 2004-09-28 | Xcyte Therapies, Inc. | Simultaneous stimulation and concentration of cells |
US7572631B2 (en) * | 2000-02-24 | 2009-08-11 | Invitrogen Corporation | Activation and expansion of T cells |
JP2003534283A (ja) * | 2000-05-25 | 2003-11-18 | エクサイト セラピーズ, インコーポレイテッド | 天然で誘導されたかまたは人工的に誘導された免疫抑制後にt細胞免疫サーベイランスを回復もしくは増強するための方法 |
US8178098B2 (en) | 2001-04-03 | 2012-05-15 | National Jewish Health | Method to inhibit airway hyperresponsiveness using aerosolized T cell receptor antibodies |
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JP2006506987A (ja) * | 2002-06-28 | 2006-03-02 | エクサイト セラピーズ インコーポレーティッド | 自己免疫および臓器または造血幹細胞移植に関連する免疫学的欠損を有する患者における免疫レパートリー回復のための組成物および方法 |
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US20150174242A1 (en) | 2013-12-19 | 2015-06-25 | Mayo Foundation For Medical Education And Research | Monovalent anti-cd3 adjuvants |
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CN109071627B (zh) | 2016-02-05 | 2023-04-04 | 奥里尼斯生物科学私人有限公司 | Cd8结合剂 |
TWI790206B (zh) | 2016-07-18 | 2023-01-21 | 法商賽諾菲公司 | 特異性結合至cd3和cd123的雙特異性抗體樣結合蛋白 |
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US20220348660A1 (en) | 2019-10-02 | 2022-11-03 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for the treatment of adult t-cell leukemia/lymphoma |
EP4117727A2 (de) | 2020-03-10 | 2023-01-18 | Tiziana Life Sciences PLC | Zusammensetzungen von il-6/il-6r-antikörpern und verfahren zur verwendung davon |
EP4168537A1 (de) | 2020-06-17 | 2023-04-26 | Tiziana Life Sciences PLC | Zusammensetzungen und verfahren zur verstärkung von t-zelltherapien mit chimärem antigenrezeptor (car) |
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US5885573A (en) * | 1993-06-01 | 1999-03-23 | Arch Development Corporation | Methods and materials for modulation of the immunosuppressive activity and toxicity of monoclonal antibodies |
AU7107794A (en) * | 1993-06-10 | 1995-01-03 | Regents Of The University Of Michigan, The | Cd28 pathway immunosuppression |
WO1995003408A1 (en) * | 1993-07-26 | 1995-02-02 | Dana-Farber Cancer Institute | B7-2: ctl a4/cd 28 counter receptor |
AU7526894A (en) * | 1993-08-16 | 1995-03-14 | Arch Development Corporation | B7-2: ctla4/cd28 counter receptor |
AUPQ960500A0 (en) * | 2000-08-23 | 2000-09-14 | Infinity Beautification Enterprises Pty Ltd | A planter box |
-
1990
- 1990-10-26 CA CA002071478A patent/CA2071478A1/en not_active Abandoned
- 1990-10-26 AT AT90916853T patent/ATE168272T1/de not_active IP Right Cessation
- 1990-10-26 DE DE69032484T patent/DE69032484T4/de not_active Expired - Lifetime
- 1990-10-26 JP JP2515665A patent/JP2546544B2/ja not_active Expired - Lifetime
- 1990-10-26 EP EP98100138A patent/EP0839536A1/de not_active Withdrawn
- 1990-10-26 EP EP90916853A patent/EP0497883B1/de not_active Expired - Lifetime
- 1990-10-26 AU AU66423/90A patent/AU6642390A/en not_active Abandoned
- 1990-10-26 DE DE69032484A patent/DE69032484D1/de not_active Expired - Fee Related
- 1990-10-26 WO PCT/US1990/006177 patent/WO1991006319A1/en active IP Right Grant
-
1994
- 1994-08-05 US US08/286,805 patent/US6113901A/en not_active Expired - Lifetime
-
1995
- 1995-06-02 US US08/458,462 patent/US6143297A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DE69032484T4 (de) | 1999-09-16 |
DE69032484T2 (de) | 1999-03-11 |
AU6642390A (en) | 1991-05-31 |
CA2071478A1 (en) | 1991-04-28 |
US6143297A (en) | 2000-11-07 |
EP0497883B1 (de) | 1998-07-15 |
ATE168272T1 (de) | 1998-08-15 |
US6113901A (en) | 2000-09-05 |
EP0497883A1 (de) | 1992-08-12 |
JP2546544B2 (ja) | 1996-10-23 |
WO1991006319A1 (en) | 1991-05-16 |
JPH05504554A (ja) | 1993-07-15 |
EP0839536A1 (de) | 1998-05-06 |
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