NO2640734T3 - - Google Patents

Info

Publication number
NO2640734T3
NO2640734T3 NO11799501A NO11799501A NO2640734T3 NO 2640734 T3 NO2640734 T3 NO 2640734T3 NO 11799501 A NO11799501 A NO 11799501A NO 11799501 A NO11799501 A NO 11799501A NO 2640734 T3 NO2640734 T3 NO 2640734T3
Authority
NO
Norway
Application number
NO11799501A
Other languages
Norwegian (no)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of NO2640734T3 publication Critical patent/NO2640734T3/no

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/7036Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D79/00Kinds or details of packages, not otherwise provided for
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00Processes for the preparation of sugar derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/22Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/228Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to adjacent ring-carbon atoms of the cyclohexane rings
    • C07H15/23Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to adjacent ring-carbon atoms of the cyclohexane rings with only two saccharide radicals in the molecule, e.g. ambutyrosin, butyrosin, xylostatin, ribostamycin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C07H5/04Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
    • C07H5/06Aminosugars

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Mechanical Engineering (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO11799501A 2010-11-18 2011-11-17 NO2640734T3 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41495610P 2010-11-18 2010-11-18
PCT/IL2011/000889 WO2012066546A1 (en) 2010-11-18 2011-11-17 Aminoglycosides and uses thereof in treating genetic disorders

Publications (1)

Publication Number Publication Date
NO2640734T3 true NO2640734T3 (pt) 2018-03-17

Family

ID=45390144

Family Applications (1)

Application Number Title Priority Date Filing Date
NO11799501A NO2640734T3 (pt) 2010-11-18 2011-11-17

Country Status (18)

Country Link
US (7) US8895519B2 (pt)
EP (2) EP2640734B1 (pt)
JP (3) JP5960712B2 (pt)
CA (1) CA2816789C (pt)
CY (1) CY1120082T1 (pt)
DK (1) DK2640734T3 (pt)
ES (2) ES2833938T3 (pt)
HK (1) HK1248709A1 (pt)
HR (1) HRP20180056T1 (pt)
HU (1) HUE036248T2 (pt)
IL (3) IL266495B (pt)
LT (1) LT2640734T (pt)
NO (1) NO2640734T3 (pt)
PL (1) PL2640734T3 (pt)
PT (1) PT2640734T (pt)
RS (1) RS56739B1 (pt)
SI (1) SI2640734T1 (pt)
WO (1) WO2012066546A1 (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2640734B1 (en) 2010-11-18 2017-10-18 Technion Research & Development Foundation Ltd. Aminoglycosides and uses thereof in treating genetic disorders
KR101703137B1 (ko) 2014-05-30 2017-02-07 선문대학교 산학협력단 당 부가 아미노글리코사이드 화합물, 이의 제조방법 및 이를 유효성분으로 함유하는 약학적 조성물
US20170360817A1 (en) * 2014-06-05 2017-12-21 Eloxx Pharmaceuticals Ltd. Use of aminoglycoside analogs in the treatment of rett syndrome
EP3344640A4 (en) 2015-09-02 2019-05-01 Eloxx Pharmaceuticals Ltd. AMINO-LIKES DERIVATIVES AND USES THEREOF FOR THE TREATMENT OF GENETIC DISEASES
WO2017037719A1 (en) * 2015-09-02 2017-03-09 Eloxx Pharmaceuticals Ltd. Aminoglycoside derivatives and uses thereof in treating genetic disorders
WO2017037718A1 (en) * 2015-09-02 2017-03-09 Eloxx Pharmaceuticals Ltd. Aminoglycoside derivatives and uses thereof in treating genetic disorders
EP3400232A4 (en) * 2016-01-05 2019-10-16 Eloxx Pharmaceuticals Ltd. AMINO-L-KOSIDE DERIVATIVES AND USES THEREOF FOR THE TREATMENT OF GENETIC DISEASES
EP3609902A4 (en) * 2017-03-15 2021-01-06 Eloxx Pharmaceuticals Ltd. LARGE-SCALE PREPARATION OF PSEUDO-TRISACCHARIDE AMINOGLYCOSIDES AND INTERMEDIARIES THEREOF
WO2019237076A1 (en) * 2018-06-07 2019-12-12 Eloxx Pharmaceuticals, Inc. Methods, compositions, and kits for inducing readthrough
KR102067477B1 (ko) * 2018-06-20 2020-01-17 고려대학교 산학협력단 스킬로이노사민을 포함하는 아미노사이클리톨 화합물, 이의 제조방법 및 이를 함유하는 약학 조성물
EP3886864A4 (en) * 2018-11-29 2022-08-10 Eloxx Pharmaceuticals METHODS, COMPOSITIONS AND KITS FOR THE TREATMENT OF EYE DISEASES
WO2021061873A1 (en) * 2019-09-23 2021-04-01 Eloxx Pharmaceuticals, Inc. Methods, compositions, and kits for treating polycystic kidney disease
EP4230196A1 (en) 2022-02-21 2023-08-23 Som Innovation Biotech, S.A. Compounds for use in the treatment of dystrophinopathies

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5960712A (ja) 1982-09-30 1984-04-06 Toshiba Corp デ−タ判別装置
WO2005078099A1 (en) 2004-02-17 2005-08-25 The Hospital For Sick Children Mecp2e1 gene
PT2390255T (pt) * 2006-04-03 2016-10-24 Technion Res & Dev Foundation Novos aminoglicosídeos e utilizações destes no tratamento de distúrbios genéticos
EP2640734B1 (en) 2010-11-18 2017-10-18 Technion Research & Development Foundation Ltd. Aminoglycosides and uses thereof in treating genetic disorders
US20170360817A1 (en) 2014-06-05 2017-12-21 Eloxx Pharmaceuticals Ltd. Use of aminoglycoside analogs in the treatment of rett syndrome

Also Published As

Publication number Publication date
US20170182078A1 (en) 2017-06-29
US8895519B2 (en) 2014-11-25
EP2640734B1 (en) 2017-10-18
PT2640734T (pt) 2018-01-22
US20180200276A1 (en) 2018-07-19
HK1248709A1 (zh) 2018-10-19
JP5960712B2 (ja) 2016-08-02
IL284067B (en) 2022-03-01
JP2013542981A (ja) 2013-11-28
US9943533B2 (en) 2018-04-17
US10398718B2 (en) 2019-09-03
JP2016121168A (ja) 2016-07-07
US20210228608A1 (en) 2021-07-29
JP2018123135A (ja) 2018-08-09
HUE036248T2 (hu) 2018-06-28
CY1120082T1 (el) 2018-12-12
LT2640734T (lt) 2018-02-12
JP6758338B2 (ja) 2020-09-23
DK2640734T3 (en) 2018-01-22
IL277063B (en) 2021-07-29
US20190224226A9 (en) 2019-07-25
PL2640734T3 (pl) 2018-04-30
IL266495B (en) 2020-09-30
ES2833938T3 (es) 2021-06-16
IL277063A (en) 2020-10-29
RS56739B1 (sr) 2018-03-30
CA2816789A1 (en) 2012-05-24
US20130237489A1 (en) 2013-09-12
IL284067A (en) 2021-07-29
IL266495A (en) 2019-07-31
ES2655916T3 (es) 2018-02-22
US10973839B2 (en) 2021-04-13
CA2816789C (en) 2018-12-11
HRP20180056T1 (hr) 2018-02-09
SI2640734T1 (en) 2018-02-28
EP3296311A1 (en) 2018-03-21
EP3296311B1 (en) 2020-09-30
WO2012066546A1 (en) 2012-05-24
EP2640734A1 (en) 2013-09-25
US9175029B2 (en) 2015-11-03
US20200078386A1 (en) 2020-03-12
US11865128B2 (en) 2024-01-09
US9616079B2 (en) 2017-04-11
US20140357590A1 (en) 2014-12-04
US20160074425A1 (en) 2016-03-17

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