NO2488513T3 - - Google Patents
Info
- Publication number
- NO2488513T3 NO2488513T3 NO10776598A NO10776598A NO2488513T3 NO 2488513 T3 NO2488513 T3 NO 2488513T3 NO 10776598 A NO10776598 A NO 10776598A NO 10776598 A NO10776598 A NO 10776598A NO 2488513 T3 NO2488513 T3 NO 2488513T3
- Authority
- NO
- Norway
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4709—Amyloid plaque core protein
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Ophthalmology & Optometry (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Neurosurgery (AREA)
- Microbiology (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP09173184A EP2311823A1 (en) | 2009-10-15 | 2009-10-15 | 2,6-Diaminopyridine compounds for treating diseases associated with amyloid proteins or for treating ocular diseases |
PCT/EP2010/065439 WO2011045383A2 (en) | 2009-10-15 | 2010-10-14 | 2, 6 -diaminopyridine compounds for treating diseases associated with amyloid proteins or for treating ocular diseases |
EP10776598.4A EP2488513B1 (en) | 2009-10-15 | 2010-10-14 | 2,6-Diaminopyridine compounds for treating diseases associated with amyloid proteins or for treating ocular diseases |
Publications (1)
Publication Number | Publication Date |
---|---|
NO2488513T3 true NO2488513T3 (no) | 2018-05-26 |
Family
ID=41800516
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO10776598A NO2488513T3 (no) | 2009-10-15 | 2010-10-14 |
Country Status (13)
Country | Link |
---|---|
US (2) | US8916590B2 (no) |
EP (2) | EP2311823A1 (no) |
JP (1) | JP5662460B2 (no) |
CN (2) | CN104262243B (no) |
AU (1) | AU2010305770B2 (no) |
BR (1) | BR112012008843B1 (no) |
CA (1) | CA2777509C (no) |
DK (1) | DK2488513T3 (no) |
ES (1) | ES2657701T3 (no) |
MX (1) | MX2012004388A (no) |
NO (1) | NO2488513T3 (no) |
RU (1) | RU2538208C2 (no) |
WO (1) | WO2011045383A2 (no) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2311823A1 (en) | 2009-10-15 | 2011-04-20 | AC Immune S.A. | 2,6-Diaminopyridine compounds for treating diseases associated with amyloid proteins or for treating ocular diseases |
EP2854804B1 (en) * | 2012-05-30 | 2019-11-20 | F.Hoffmann-La Roche Ag | Pyrrolidino heterocycles |
US11099185B2 (en) * | 2016-02-29 | 2021-08-24 | Maintect Gmbh | Predictive markers useful in the treatment of wet age-related macular degeneration |
CN106986876B (zh) * | 2017-03-20 | 2019-02-19 | 北京理工大学 | 一种靶向标记眼晶体上皮细胞的荧光探针、其制备及应用 |
AU2020360928A1 (en) | 2019-09-30 | 2022-04-14 | Nippon Chemiphar Co., Ltd. | Azepan derivative |
Family Cites Families (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5023A (en) * | 1847-03-20 | Stocking-loom | ||
BE606550A (no) * | 1960-07-27 | |||
US3651023A (en) * | 1968-07-02 | 1972-03-21 | Stamicarbon | Preparation of polyamides with special properties |
SU400583A1 (ru) | 1971-07-05 | 1973-10-01 | Донецкое отделение физико органической химии Института физической химии Украинской ССР | Способ получения 2, 3-бисметилал\инопиридина |
JPS604171A (ja) * | 1983-06-23 | 1985-01-10 | Showa Denko Kk | N−アルキルアミノピラゾ−ル誘導体とその製造法および除草剤 |
BR9509421A (pt) | 1994-10-21 | 1997-09-30 | Innogenetics Nv | Novas sequências de genotipos de vírus de hepatite C e uso como agentes profiláticos terapêuticos e diagnósticos |
CN1165482A (zh) | 1994-11-10 | 1997-11-19 | 科西雷佩蒂斯公司 | 用作蛋白激酶抑制剂的吡唑药物组合物 |
US5756662A (en) | 1995-03-14 | 1998-05-26 | Corixa Corporation | Compounds and methods for the detection of T. cruzi infection |
CA2290712C (en) | 1995-09-22 | 2003-09-09 | Wakunaga Pharmaceutical Co., Ltd. | Novel pyridonecarboxylic acid derivatives or their salts, and antibacterial agents containing the same as their effective components |
US6385594B1 (en) | 1998-05-08 | 2002-05-07 | Lendingtree, Inc. | Method and computer network for co-ordinating a loan over the internet |
US6436915B1 (en) * | 2000-04-07 | 2002-08-20 | Kinetek Pharmaceuticals, Inc. | Pyrazole compounds |
EP1379239B1 (en) | 2001-03-29 | 2007-09-12 | Eli Lilly And Company | N-(2-arylethyl) benzylamines as antagonists of the 5-ht6 receptor |
AUPR688101A0 (en) | 2001-08-08 | 2001-08-30 | Luminis Pty Limited | Protein domains and their ligands |
WO2003040402A2 (en) | 2001-11-09 | 2003-05-15 | The Regents Of The University Of California | Alpha-helix mimicry by a class of organic molecules |
GB0128287D0 (en) | 2001-11-26 | 2002-01-16 | Smithkline Beecham Plc | Novel method and compounds |
US7574396B2 (en) | 2001-12-04 | 2009-08-11 | Andrew Kalotay Associates, Inc. | Method of and apparatus for administering an asset-backed security using coupled lattice efficiency analysis |
GB0206723D0 (en) | 2002-03-21 | 2002-05-01 | Glaxo Group Ltd | Novel compounds |
DE10221052A1 (de) | 2002-05-10 | 2003-12-04 | Transmit Technologietransfer | Wirkstoffe zu Therapie, Diagnostik und Prophylaxe von Erkrankungen, bei denen abnorme Proteinstrukturen auftreten |
PL210065B1 (pl) | 2002-09-25 | 2011-11-30 | Memory Pharm Corp | Związki indazole, benzotiazole i benzoizotiazole, kompozycje farmaceutyczne je zawierające oraz zastosowanie związków |
US20060135403A1 (en) | 2002-12-24 | 2006-06-22 | Francine Gervais | Therapeutic formulations for the treatment of beta-amyloid related diseases |
US20040205019A1 (en) | 2003-04-08 | 2004-10-14 | Lendingtree, Inc. | Method and system for selecting qualification forms for financial services and financial products |
EP1628666B1 (en) | 2003-05-14 | 2015-09-23 | NeuroGenetic Pharmaceuticals, Inc. | Compouds and uses thereof in modulating amyloid beta |
US7732467B2 (en) * | 2003-05-15 | 2010-06-08 | Alzheimer's Institute Of America, Inc. | Method for reducing amyloid deposition, amyloid neurotoxicity and microgliosis |
MXPA05013631A (es) | 2003-06-30 | 2006-02-24 | Daiichi Seiyaku Co | Derivado heterociclico de metilsulfona. |
TWI301760B (en) | 2004-02-27 | 2008-10-11 | Merz Pharma Gmbh & Co Kgaa | Tetrahydroquinolinones and their use as antagonists of metabotropic glutamate receptors |
KR101331786B1 (ko) | 2004-09-22 | 2013-11-21 | 얀센 파마슈티카 엔.브이. | Mdm2 및 p53간의 상호작용 저해제 |
WO2006039327A2 (en) | 2004-10-01 | 2006-04-13 | Merck & Co., Inc. | Methods of treatment or prophylaxis of amyloidogenic diseases of the eye or optic nerve |
EP1831170A4 (en) | 2004-12-14 | 2009-10-14 | Astrazeneca Ab | SUBSTITUTED AMINOPYRIDINES AND THEIR USE |
US20070073504A1 (en) | 2005-09-26 | 2007-03-29 | Bristol-Myers Squibb Company | Configurable component handling device |
US7882025B1 (en) | 2005-11-18 | 2011-02-01 | Federal Home Loan Mortgage Corporation (Freddie Mac) | Systems and methods of a mortgage pricing service |
KR101152557B1 (ko) | 2005-12-12 | 2012-09-07 | 에이씨 이뮨 에스.에이. | 치료 백신 |
RU2551782C2 (ru) | 2005-12-12 | 2015-05-27 | Ац Иммуне Са | Специфические в отношении амилоида бета (а бета) 1-42 моноклональные антитела, обладающие терапевтическими свойствами |
EP1829867A1 (en) | 2006-03-03 | 2007-09-05 | Laboratorios Del Dr. Esteve, S.A. | Imidazole compounds having pharmaceutical activity towards the sigma receptor |
US8198094B2 (en) * | 2006-03-15 | 2012-06-12 | The Brigham And Women's Hospital, Inc. | Methods of using gelsolin levels to characterize a subject's risk of developing rheumatoid arthritis |
WO2008011348A2 (en) | 2006-07-14 | 2008-01-24 | Ac Immune S.A. | Humanized antibody against amyloid beta |
US20080109347A1 (en) | 2006-08-22 | 2008-05-08 | Pilcher John W | System and methods for constructing loans |
CA2670418A1 (en) | 2006-11-24 | 2008-05-29 | Ac Immune Sa | N-(methyl)-1h-pyrazol-3-amine, n-(methyl)-pyridin-2-amine and n-(methyl)-thiazol-2-amine derivatives for the treatment of diseases associated with amyloid or amyloid-like proteins, like e.g. alzheimers's |
US8084613B2 (en) * | 2007-05-14 | 2011-12-27 | Nippon Soda Co., Ltd. | Tetrazoyloxime derivative and plant disease control agent |
US8244618B1 (en) | 2009-01-08 | 2012-08-14 | Amherst Holdings, LLC | Loan information analysis system and method |
EP2311823A1 (en) * | 2009-10-15 | 2011-04-20 | AC Immune S.A. | 2,6-Diaminopyridine compounds for treating diseases associated with amyloid proteins or for treating ocular diseases |
-
2009
- 2009-10-15 EP EP09173184A patent/EP2311823A1/en not_active Withdrawn
-
2010
- 2010-10-14 JP JP2012533632A patent/JP5662460B2/ja active Active
- 2010-10-14 EP EP10776598.4A patent/EP2488513B1/en active Active
- 2010-10-14 RU RU2012119757/04A patent/RU2538208C2/ru active
- 2010-10-14 DK DK10776598.4T patent/DK2488513T3/da active
- 2010-10-14 NO NO10776598A patent/NO2488513T3/no unknown
- 2010-10-14 CN CN201410407476.7A patent/CN104262243B/zh active Active
- 2010-10-14 CN CN201080056685.1A patent/CN102656161B/zh active Active
- 2010-10-14 BR BR112012008843-2A patent/BR112012008843B1/pt active IP Right Grant
- 2010-10-14 CA CA2777509A patent/CA2777509C/en active Active
- 2010-10-14 AU AU2010305770A patent/AU2010305770B2/en not_active Ceased
- 2010-10-14 ES ES10776598.4T patent/ES2657701T3/es active Active
- 2010-10-14 MX MX2012004388A patent/MX2012004388A/es active IP Right Grant
- 2010-10-14 WO PCT/EP2010/065439 patent/WO2011045383A2/en active Application Filing
- 2010-10-15 US US12/905,356 patent/US8916590B2/en active Active
-
2014
- 2014-09-30 US US14/502,907 patent/US9701660B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
CA2777509C (en) | 2015-06-02 |
EP2488513B1 (en) | 2017-12-27 |
AU2010305770B2 (en) | 2014-05-22 |
JP5662460B2 (ja) | 2015-01-28 |
CN104262243B (zh) | 2017-04-12 |
CA2777509A1 (en) | 2011-04-21 |
US20110092537A1 (en) | 2011-04-21 |
EP2488513A2 (en) | 2012-08-22 |
CN102656161B (zh) | 2015-02-18 |
CN102656161A (zh) | 2012-09-05 |
AU2010305770A1 (en) | 2012-05-03 |
EP2311823A1 (en) | 2011-04-20 |
US20150023950A1 (en) | 2015-01-22 |
ES2657701T3 (es) | 2018-03-06 |
US8916590B2 (en) | 2014-12-23 |
WO2011045383A2 (en) | 2011-04-21 |
JP2013507428A (ja) | 2013-03-04 |
RU2538208C2 (ru) | 2015-01-10 |
WO2011045383A3 (en) | 2011-06-30 |
US9701660B2 (en) | 2017-07-11 |
DK2488513T3 (da) | 2018-01-29 |
BR112012008843A2 (pt) | 2022-02-08 |
MX2012004388A (es) | 2012-06-08 |
CN104262243A (zh) | 2015-01-07 |
BR112012008843B1 (pt) | 2022-08-30 |
RU2012119757A (ru) | 2013-11-20 |