NO2385374T3 - - Google Patents
Info
- Publication number
- NO2385374T3 NO2385374T3 NO10162066A NO10162066A NO2385374T3 NO 2385374 T3 NO2385374 T3 NO 2385374T3 NO 10162066 A NO10162066 A NO 10162066A NO 10162066 A NO10162066 A NO 10162066A NO 2385374 T3 NO2385374 T3 NO 2385374T3
- Authority
- NO
- Norway
Links
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2405/00—Assays, e.g. immunoassays or enzyme assays, involving lipids
- G01N2405/04—Phospholipids, i.e. phosphoglycerides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2570/00—Omics, e.g. proteomics, glycomics or lipidomics; Methods of analysis focusing on the entire complement of classes of biological molecules or subsets thereof, i.e. focusing on proteomes, glycomes or lipidomes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/32—Cardiovascular disorders
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/32—Cardiovascular disorders
- G01N2800/323—Arteriosclerosis, Stenosis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/32—Cardiovascular disorders
- G01N2800/324—Coronary artery diseases, e.g. angina pectoris, myocardial infarction
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/32—Cardiovascular disorders
- G01N2800/325—Heart failure or cardiac arrest, e.g. cardiomyopathy, congestive heart failure
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/50—Determining the risk of developing a disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- Endocrinology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Vascular Medicine (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicinal Preparation (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP10162066.4A EP2385374B2 (en) | 2010-05-05 | 2010-05-05 | Lipidomic biomarkers for atherosclerosis and cardiovascular disease |
Publications (1)
Publication Number | Publication Date |
---|---|
NO2385374T3 true NO2385374T3 (zh) | 2014-06-07 |
Family
ID=42315849
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO10162066A NO2385374T3 (zh) | 2010-05-05 | 2010-05-05 | |
NO11719802A NO2567240T3 (zh) | 2010-05-05 | 2011-05-05 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO11719802A NO2567240T3 (zh) | 2010-05-05 | 2011-05-05 |
Country Status (9)
Country | Link |
---|---|
US (5) | US9046538B2 (zh) |
EP (3) | EP2385374B2 (zh) |
JP (1) | JP5871244B2 (zh) |
CN (1) | CN102971633B (zh) |
CA (1) | CA2798238C (zh) |
DK (2) | DK2385374T4 (zh) |
ES (2) | ES2455124T5 (zh) |
NO (2) | NO2385374T3 (zh) |
WO (1) | WO2011138419A1 (zh) |
Families Citing this family (52)
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US9046540B2 (en) * | 2008-09-29 | 2015-06-02 | Plaxgen Inc. | Assay, composition and non-enzymatic mechanism of statin in modulating lipid metabolism |
CN102884435A (zh) | 2009-11-27 | 2013-01-16 | 贝克Idi心脏和糖尿病研究院控股有限公司 | 用于稳定和不稳定心脏病的脂质生物标记物 |
BR112012018771A2 (pt) | 2010-01-29 | 2017-06-20 | Metanomics Gmbh | ''método para dianosticar insuficência cardíaca em um sujeito'' |
EP2385374B2 (en) | 2010-05-05 | 2018-02-28 | Zora Biosciences OY | Lipidomic biomarkers for atherosclerosis and cardiovascular disease |
CA2801459C (en) * | 2010-06-20 | 2018-04-24 | Zora Biosciences Oy | Lipidomic biomarkers for identification of high-risk coronary artery disease patients |
US8765479B1 (en) * | 2011-03-13 | 2014-07-01 | Atherotech, Inc. | Methods for determining the risk of coronary heart disease and clinical manifestations of coronary heart disease |
US9541565B2 (en) | 2011-04-08 | 2017-01-10 | Zora Biosciences Oy | Biomarkers for sensitive detection of statin-induced muscle toxicity |
EP2592423A1 (en) | 2011-11-08 | 2013-05-15 | Zora Biosciences OY | Lipidomic biomarkers for the prediction of cardiovascular outcomes in coronary artery disease patients not undergoing statin treatment |
EP2592422A1 (en) * | 2011-11-08 | 2013-05-15 | Zora Biosciences OY | Lipidomic biomarkers for the prediction of cardiovascular outcomes in coronary artery disease patients undergoing statin treatment |
EP2642293A1 (en) | 2012-03-22 | 2013-09-25 | Nestec S.A. | 9-oxo-octadecadienoic acid (9-oxo-HODE)as as biomarker for healthy ageing |
EP2642295A1 (en) * | 2012-03-22 | 2013-09-25 | Nestec S.A. | 1-O-alkyl-2-acylglycerophosphocholine (PC-O) 40:1 as biomarker for healthy ageing |
ES2552371T3 (es) * | 2012-05-25 | 2015-11-27 | Zora Biosciences Oy | Biomarcadores sensibles, eficaces e inocuos, para la inhibición de la Proproteína Convertasa Subtilisina/Kexina de tipo 9 (PCSK9) |
CN103149312B (zh) * | 2013-02-05 | 2015-02-04 | 东北农业大学 | 一种利用超高效液相色谱串联四级杆质谱分析婴儿乳粉中唾液酸的方法 |
EP2778686B1 (en) * | 2013-03-13 | 2016-07-27 | Academisch Ziekenhuis Leiden h.o.d.n. LUMC | Lipidomics of familial longevity |
CN105723223B (zh) * | 2013-11-14 | 2019-04-09 | 雀巢产品技术援助有限公司 | 预测健康衰老的脂质生物标志物 |
KR101660328B1 (ko) | 2014-01-14 | 2016-09-27 | 한국과학기술연구원 | 심혈관 질환 진단용 바이오 마커 |
NZ759799A (en) | 2014-04-10 | 2022-12-23 | MEP Equine Solutions LLC | Method for the quantification of parasite eggs in feces |
US9347960B2 (en) | 2014-06-16 | 2016-05-24 | Zora Biosciences, Oy | Ceramides and their use in diagnosing CVD |
EP3177939A1 (en) | 2014-09-11 | 2017-06-14 | Liposcience, Inc. | Cardiovascular risk evaluations using a risk parameter that includes an hdl and inflammatory biomarker interaction parameter |
US10996231B2 (en) | 2014-12-16 | 2021-05-04 | Washington University | Ceramides for evaluating risk of cardiovascular disease |
CA2973116C (en) * | 2015-01-09 | 2023-08-15 | Global Genomics Group, LLC | Blood based biomarkers for diagnosing atherosclerotic coronary artery disease |
EP3121599A1 (en) * | 2015-07-23 | 2017-01-25 | Medizinische Hochschule Hannover | Analysis for atherosclerosis |
WO2017029401A1 (en) * | 2015-08-19 | 2017-02-23 | Metanomics Gmbh | Means and methods for diagnosing cardiac disease in a subject |
WO2017028308A1 (en) * | 2015-08-20 | 2017-02-23 | Bgi Shenzhen | Biomarkers for coronary heart disease |
WO2017097852A2 (en) * | 2015-12-07 | 2017-06-15 | Zora Biosciences Oy | Use of ceramides and lpls in diagnosing cvd |
CN105445408B (zh) * | 2016-01-25 | 2018-06-12 | 齐炼文 | 诊断区分冠状动脉粥样硬化和稳定型心绞痛的代谢标志物 |
CN105486778B (zh) * | 2016-01-25 | 2017-11-03 | 齐炼文 | 诊断区分稳定型心绞痛和急性冠脉综合征的代谢标志物 |
CN108872404A (zh) * | 2017-05-09 | 2018-11-23 | 中国科学院上海生命科学研究院 | 超长链饱和脂肪酸或其检测试剂在代谢综合征患病风险预测中的应用 |
CN107144624B (zh) * | 2017-05-15 | 2021-01-05 | 中国科学院生态环境研究中心 | 甄别二氧化硅颗粒来源的方法 |
TWI835735B (zh) * | 2017-06-12 | 2024-03-21 | 比利時商健生藥品公司 | 減少或預防第ii型糖尿病患者中心血管事件之方法 |
CN109870536B (zh) * | 2017-12-05 | 2021-08-10 | 中国科学院大连化学物理研究所 | 一种基于液相色谱-质谱联用的高覆盖脂质组学分析方法 |
CN114062581A (zh) * | 2017-12-14 | 2022-02-18 | 江苏豪思生物科技有限公司 | 一种用于评估冠状动脉疾病的试剂盒 |
WO2019119049A1 (en) * | 2017-12-20 | 2019-06-27 | Baker Heart and Diabetes Institute | Method of predicting drug therapeutic responder status and methods of treatment |
CN110433282B (zh) * | 2018-05-04 | 2023-03-14 | 上海交通大学医学院附属瑞金医院 | 胰高血糖素样肽-1在制备治疗钙化性主动脉瓣疾病药物方面的应用 |
US20220003791A1 (en) * | 2018-12-06 | 2022-01-06 | Zora Biosciences Oy | Biomarkers for cardiovascular events |
US20220214367A1 (en) * | 2019-04-15 | 2022-07-07 | Board Of Regents, The University Of Texas System | Calibration methods and compositions for biomolecule analysis |
WO2020242796A1 (en) * | 2019-05-28 | 2020-12-03 | Ohio University | Assays and methods for screening for cardiovascular disease using ldl subclasses and endothelial nitric oxide/peroxynitrite balance |
CN112305122B (zh) * | 2020-10-30 | 2021-07-13 | 河北医科大学第二医院 | 代谢物标志物及其在疾病中的应用 |
CN112305124B (zh) * | 2020-10-30 | 2022-03-04 | 河北医科大学第二医院 | 一种生物标志物及其在疾病诊断中的应用 |
CN112147344B (zh) * | 2020-10-30 | 2021-07-13 | 河北医科大学第二医院 | 动脉粥样硬化性脑梗死的代谢标志物及其在诊疗中的应用 |
CN112305119B (zh) * | 2020-10-30 | 2021-08-17 | 河北医科大学第二医院 | 动脉粥样硬化性脑梗死的生物标志物及其应用 |
CN113782177A (zh) * | 2020-12-02 | 2021-12-10 | 北京市心肺血管疾病研究所 | 一种用于鉴别诊断冠心病患者斑块稳定性的数据处理装置、系统 |
CN112630330B (zh) * | 2020-12-08 | 2021-12-21 | 河北医科大学第二医院 | 小分子物质在脑梗死诊断中的应用 |
CA3217229A1 (en) * | 2021-04-21 | 2022-10-27 | Albert Einstein College Of Medicine | Methods of stabilizing the neuronal proteome against collapse and protecting vascular cells |
CN113295793B (zh) * | 2021-05-20 | 2022-11-04 | 复旦大学附属中山医院 | 预测早期糖尿病以及糖尿病发生的生物标志物、其检测方法与应用 |
CN116087487A (zh) * | 2021-11-08 | 2023-05-09 | 中国医学科学院阜外医院 | 糖尿病患者早期预测心血管疾病(cvd)的生物标志物及其用途 |
CN113960222B (zh) * | 2021-12-23 | 2022-02-25 | 中国中医科学院医学实验中心 | 基于血清样本的胆汁酸全通路代谢轮廓的检测方法及其应用 |
CN113960221B (zh) * | 2021-12-23 | 2022-02-25 | 中国中医科学院医学实验中心 | 基于粪便样本的胆汁酸全通路代谢轮廓的检测方法及其应用 |
CN114705873B (zh) * | 2022-06-06 | 2022-08-26 | 首都医科大学宣武医院 | 脂质作为颈动脉粥样硬化斑块诊断标志物的用途 |
CN115267214A (zh) * | 2022-08-10 | 2022-11-01 | 南方医科大学珠江医院 | 一种脂质代谢标志物、其筛选方法及其在颅内动脉瘤中的应用 |
WO2024192471A1 (en) * | 2023-03-20 | 2024-09-26 | Baker Heart and Diabetes Institute | Methods of assessing metabolic health |
CN118258931B (zh) * | 2024-05-29 | 2024-08-16 | 山东第一医科大学附属省立医院(山东省立医院) | 用于预警女性动脉粥样硬化的代谢标志物组合及检测试剂盒 |
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US8137977B2 (en) * | 2006-04-24 | 2012-03-20 | Children's Hospital & Research Center At Oakland | Lipidomic approaches to determining drug response phenotypes in cardiovascular disease |
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CN102884435A (zh) * | 2009-11-27 | 2013-01-16 | 贝克Idi心脏和糖尿病研究院控股有限公司 | 用于稳定和不稳定心脏病的脂质生物标记物 |
BR112012018771A2 (pt) * | 2010-01-29 | 2017-06-20 | Metanomics Gmbh | ''método para dianosticar insuficência cardíaca em um sujeito'' |
EP2385374B2 (en) | 2010-05-05 | 2018-02-28 | Zora Biosciences OY | Lipidomic biomarkers for atherosclerosis and cardiovascular disease |
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2010
- 2010-05-05 EP EP10162066.4A patent/EP2385374B2/en active Active
- 2010-05-05 ES ES10162066.4T patent/ES2455124T5/es active Active
- 2010-05-05 NO NO10162066A patent/NO2385374T3/no unknown
- 2010-05-05 DK DK10162066.4T patent/DK2385374T4/en active
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2011
- 2011-05-05 EP EP18165052.4A patent/EP3399318B1/en active Active
- 2011-05-05 NO NO11719802A patent/NO2567240T3/no unknown
- 2011-05-05 DK DK11719802.8T patent/DK2567240T4/da active
- 2011-05-05 EP EP11719802.8A patent/EP2567240B2/en active Active
- 2011-05-05 CA CA2798238A patent/CA2798238C/en active Active
- 2011-05-05 US US13/695,766 patent/US9046538B2/en active Active
- 2011-05-05 JP JP2013508512A patent/JP5871244B2/ja active Active
- 2011-05-05 CN CN201180032921.0A patent/CN102971633B/zh active Active
- 2011-05-05 WO PCT/EP2011/057254 patent/WO2011138419A1/en active Application Filing
- 2011-05-05 ES ES11719802T patent/ES2672054T5/es active Active
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2015
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2016
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2019
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