NO20092227L - Salter og krystallformer av 2-metyl-2-[4-(3-metyl-2-okso-8-konolin-3-yl-2,3-dihydro-imidazo[4,5-C]kinolin-1-yl)-fenyl]-propionitril - Google Patents

Salter og krystallformer av 2-metyl-2-[4-(3-metyl-2-okso-8-konolin-3-yl-2,3-dihydro-imidazo[4,5-C]kinolin-1-yl)-fenyl]-propionitril

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Publication number
NO20092227L
NO20092227L NO20092227A NO20092227A NO20092227L NO 20092227 L NO20092227 L NO 20092227L NO 20092227 A NO20092227 A NO 20092227A NO 20092227 A NO20092227 A NO 20092227A NO 20092227 L NO20092227 L NO 20092227L
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NO
Norway
Prior art keywords
methyl
quinolin
salts
propionitrile
imidazo
Prior art date
Application number
NO20092227A
Other languages
English (en)
Inventor
Frank Stowasser
Markus Banziger
Sudhakar Devidasrao Garad
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Novartis Ag
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Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of NO20092227L publication Critical patent/NO20092227L/no

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01—Sulfonic acids
    • C07C309/28—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C309/29—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton of non-condensed six-membered aromatic rings
    • C07C309/30—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton of non-condensed six-membered aromatic rings of six-membered aromatic rings substituted by alkyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Foreliggende oppfinnelse angår særlig krystallinske former av 2-metyl-2-[4-(3-metyl-2-okso-8-quinolin-3-yl-2,3-dihydro-imidazo[4,5-clquinolin-1-yl)-fenyl-propionitril, dens hydrater og solvater, dens salter og hydrater og solvater av dens salter, visse fremgangsmåter for deres fremstilling, farmasøytiske sammensetninger som inneholder disse krystallinske formene og deres anvendelse i diagnostiske fremgangsmåter eller, foretrukket, for terapeutisk behandling av vannblodige dyr, særlig mennesker, og deres anvendelse som et intermediat eller for fremstilling av farmasøytiske preparater for anvendelse i diagnostiske fremgangsmåter eller, foretrukket, for den terapeutiske behandlingen av varmblodige dyr, særlig mennesker. (Fig. 1)
NO20092227A 2006-11-20 2009-06-09 Salter og krystallformer av 2-metyl-2-[4-(3-metyl-2-okso-8-konolin-3-yl-2,3-dihydro-imidazo[4,5-C]kinolin-1-yl)-fenyl]-propionitril NO20092227L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US86648306P 2006-11-20 2006-11-20
PCT/US2007/084893 WO2008064093A2 (en) 2006-11-20 2007-11-16 Salts and crystal forms of 2-methyl-2-[4-(3-methyl-2-oxo-8-quinolin-3-yl-2,3-dihydro-imidazo[4,5-c]quinolin-1-yl)-phenyl]-propionitrile

Publications (1)

Publication Number Publication Date
NO20092227L true NO20092227L (no) 2009-08-17

Family

ID=39345299

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20092227A NO20092227L (no) 2006-11-20 2009-06-09 Salter og krystallformer av 2-metyl-2-[4-(3-metyl-2-okso-8-konolin-3-yl-2,3-dihydro-imidazo[4,5-C]kinolin-1-yl)-fenyl]-propionitril

Country Status (36)

Country Link
US (2) US8436177B2 (no)
EP (2) EP2364981A1 (no)
JP (2) JP5562033B2 (no)
KR (3) KR20140091718A (no)
CN (5) CN109970735A (no)
AR (1) AR064256A1 (no)
AU (1) AU2007323820B2 (no)
BR (1) BRPI0719112A2 (no)
CA (1) CA2669199C (no)
CL (1) CL2007003316A1 (no)
CO (1) CO6382134A2 (no)
CR (1) CR10757A (no)
DO (1) DOP2009000116A (no)
EA (1) EA015677B1 (no)
EC (1) ECSP099340A (no)
GE (1) GEP20125436B (no)
GT (1) GT200900133A (no)
HK (1) HK1132739A1 (no)
HR (1) HRP20140627T1 (no)
IL (2) IL198467A (no)
JO (1) JO2903B1 (no)
MA (1) MA30967B1 (no)
MX (1) MX2009005360A (no)
MY (1) MY150216A (no)
NI (1) NI200900091A (no)
NO (1) NO20092227L (no)
NZ (1) NZ576357A (no)
PE (2) PE20120083A1 (no)
PH (1) PH12013502100A1 (no)
RS (1) RS53335B (no)
SM (1) SMP200900041B (no)
TN (1) TN2009000191A1 (no)
TW (2) TW201402567A (no)
UA (1) UA98473C2 (no)
UY (1) UY30728A1 (no)
WO (1) WO2008064093A2 (no)

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WO2008064093A2 (en) 2008-05-29
ECSP099340A (es) 2009-06-30
CN102336752A (zh) 2012-02-01
EA200900638A1 (ru) 2009-12-30
TN2009000191A1 (en) 2010-10-18
CO6382134A2 (es) 2012-02-15
WO2008064093A3 (en) 2008-08-14
DOP2009000116A (es) 2009-05-31
GEP20125436B (en) 2012-03-26
IL219877A0 (en) 2012-06-28
IL198467A (en) 2014-11-30
JO2903B1 (en) 2015-09-15
KR20090080530A (ko) 2009-07-24
KR20140091718A (ko) 2014-07-22
SMP200900041B (it) 2009-09-07
PH12013502100A1 (en) 2015-09-21
CL2007003316A1 (es) 2008-06-27
HK1132739A1 (en) 2010-03-05
EP2094700B1 (en) 2014-04-02
EP2094700A2 (en) 2009-09-02
TW201402567A (zh) 2014-01-16
EA015677B1 (ru) 2011-10-31
US20100168153A1 (en) 2010-07-01
CR10757A (es) 2009-06-11
CA2669199A1 (en) 2008-05-29
RS53335B (en) 2014-10-31
NZ576357A (en) 2011-01-28
CN109970735A (zh) 2019-07-05
NI200900091A (es) 2010-02-17
US8436177B2 (en) 2013-05-07
MX2009005360A (es) 2009-06-05
GT200900133A (es) 2010-05-21
PE20120083A1 (es) 2012-03-01
AU2007323820B2 (en) 2012-02-23
TWI417292B (zh) 2013-12-01
JP5562033B2 (ja) 2014-07-30
UA98473C2 (ru) 2012-05-25
IL198467A0 (en) 2010-02-17
JP2010510240A (ja) 2010-04-02
SMAP200900041A (it) 2009-07-14
CN102993202A (zh) 2013-03-27
PE20081780A1 (es) 2009-01-01
AU2007323820A1 (en) 2008-05-29
CA2669199C (en) 2015-12-29
UY30728A1 (es) 2008-07-03
MA30967B1 (fr) 2009-12-01
EP2364981A1 (en) 2011-09-14
TW200827356A (en) 2008-07-01
CN106045993A (zh) 2016-10-26
AR064256A1 (es) 2009-03-25
US20130289064A1 (en) 2013-10-31
BRPI0719112A2 (pt) 2013-12-10
KR20140129396A (ko) 2014-11-06
JP2013173788A (ja) 2013-09-05
MY150216A (en) 2013-12-13
CN101541793A (zh) 2009-09-23
HRP20140627T1 (hr) 2014-09-26

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