NO20092117L - Nye lipidforbindelser - Google Patents

Nye lipidforbindelser

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Publication number
NO20092117L
NO20092117L NO20092117A NO20092117A NO20092117L NO 20092117 L NO20092117 L NO 20092117L NO 20092117 A NO20092117 A NO 20092117A NO 20092117 A NO20092117 A NO 20092117A NO 20092117 L NO20092117 L NO 20092117L
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NO
Norway
Prior art keywords
group
hydrogen atom
alkenyl
compounds
alkyl
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NO20092117A
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English (en)
Inventor
Anne Kristin Holmeide
Jenny Rosman
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Pronova Biopharma Norge As
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Application filed by Pronova Biopharma Norge As filed Critical Pronova Biopharma Norge As
Publication of NO20092117L publication Critical patent/NO20092117L/no

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    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS, COOKING OILS
    • A23D9/00—Other edible oils or fats, e.g. shortenings, cooking oils
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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    • A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
    • A61K31/10—Sulfides; Sulfoxides; Sulfones
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    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/225—Polycarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A61K31/232—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having three or more double bonds, e.g. etretinate
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    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/255—Esters, e.g. nitroglycerine, selenocyanates of sulfoxy acids or sulfur analogues thereof
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    • A61K31/265—Esters, e.g. nitroglycerine, selenocyanates of carbonic, thiocarbonic, or thiocarboxylic acids, e.g. thioacetic acid, xanthogenic acid, trithiocarbonic acid
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Abstract

Omega-3 lipidforbindelser med den generelle formel (l): der R1 og R2 er like eller forskjellige og er valgt fra et hydrogenatom, en hydroksygruppe, en alkylgruppe, et halogenatom, en alkoksygruppe, en acyloksygruppe, en acylgruppe, en alkenylgruppe, en alkynylgruppe, en arylgruppe, en alkyltiogruppe, en alkoksykarbonylgruppe, en karboksygruppe, en alkylsulfinylgruppe, en alkylsulfonylgruppe, en aminogruppe og en alkylaminogruppe; P står for et hydrogenatom; der P1, P2 og P3 er valgt fra et hydrogenatom, en alkylgruppe og en C14-C22 alkenylgruppe, der alkyl- og alkenylgruppene eventuelt er substituert med en hydroksygruppe; ; eller og Y er en C14-C22 alkenylgruppe med minst en dobbeltbinding, med E- og/eller Z-konfigurasjon; eller et hvilket som helst farmasøytisk akseptabelt kompleks, solvat, salt eller prodrug derav, med det forbehold at R1 og R2 ikke samtidig er et hydrogenatom. Det er også beskrevet farmasøytiske preparater og lipidpreparater som innbefatter slike forbindelser, og slike forbindelser for anvendelse som medikamenter, i særdeleshet for behandling av kardiovaskulære og metaboliske sykdommer.
NO20092117A 2006-11-01 2009-05-29 Nye lipidforbindelser NO20092117L (no)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US85573306P 2006-11-01 2006-11-01
SE0602310 2006-11-01
US85626806P 2006-11-03 2006-11-03
US85626906P 2006-11-03 2006-11-03
US85626706P 2006-11-03 2006-11-03
SE0602352 2006-11-03
PCT/IB2007/004588 WO2008132552A2 (en) 2006-11-01 2007-11-01 Omega-3 lipid compounds

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NO20092117L true NO20092117L (no) 2009-06-30

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US (1) US20100240616A1 (no)
EP (1) EP2129646A2 (no)
JP (1) JP5552314B2 (no)
KR (1) KR101544584B1 (no)
CN (1) CN101631757A (no)
CA (1) CA2667150A1 (no)
MX (1) MX2009004337A (no)
NO (1) NO20092117L (no)
WO (1) WO2008132552A2 (no)

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CA2765329C (en) * 2009-06-12 2018-01-02 Calanus As Oil composition, formulations comprising the oil composition, and the use thereof to reduce accumulation of visceral fat, improve glucose tolerance, and prevent or treat obesity related diseases and disorders
AU2011324909B2 (en) 2010-11-05 2016-09-08 Pronova Biopharma Norge As Methods of treatment using lipid compounds
ES2748562T3 (es) 2013-02-28 2020-03-17 Basf As Una composición que comprende un compuesto lipídico, un triglicérido y un tensioactivo, y procedimientos de uso de la misma
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GB201521085D0 (en) * 2015-11-30 2016-01-13 Biozep As Use
IL275002B2 (en) 2017-12-06 2024-04-01 Basf As Fatty acid antecedents for the treatment of nonalcoholic fatty liver disease
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WO2008132552A3 (en) 2009-01-15
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US20100240616A1 (en) 2010-09-23
CN101631757A (zh) 2010-01-20
EP2129646A2 (en) 2009-12-09
KR20090112631A (ko) 2009-10-28
WO2008132552A2 (en) 2008-11-06
CA2667150A1 (en) 2008-11-06
JP5552314B2 (ja) 2014-07-16
JP2010508261A (ja) 2010-03-18

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