NO20084993L - Forklaring, metoder, og prover for identifisering av nye smakscelle-gener og saltsmak-reseptor mal og prover som anvender disse identifiserte genene eller gen-produktene - Google Patents
Forklaring, metoder, og prover for identifisering av nye smakscelle-gener og saltsmak-reseptor mal og prover som anvender disse identifiserte genene eller gen-produkteneInfo
- Publication number
- NO20084993L NO20084993L NO20084993A NO20084993A NO20084993L NO 20084993 L NO20084993 L NO 20084993L NO 20084993 A NO20084993 A NO 20084993A NO 20084993 A NO20084993 A NO 20084993A NO 20084993 L NO20084993 L NO 20084993L
- Authority
- NO
- Norway
- Prior art keywords
- taste
- genes
- methods
- umami
- bitter
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 13
- 235000019640 taste Nutrition 0.000 title abstract 8
- 238000000034 method Methods 0.000 title abstract 6
- 235000019608 salt taste sensations Nutrition 0.000 title abstract 4
- 108091005708 gustatory receptors Proteins 0.000 title abstract 2
- 235000019583 umami taste Nutrition 0.000 abstract 5
- 210000004027 cell Anatomy 0.000 abstract 4
- 235000009508 confectionery Nutrition 0.000 abstract 4
- 230000008447 perception Effects 0.000 abstract 4
- 238000003556 assay Methods 0.000 abstract 2
- 230000001079 digestive effect Effects 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- 239000000796 flavoring agent Substances 0.000 abstract 2
- 235000019634 flavors Nutrition 0.000 abstract 2
- 210000000214 mouth Anatomy 0.000 abstract 2
- 229940124606 potential therapeutic agent Drugs 0.000 abstract 2
- 208000010470 Ageusia Diseases 0.000 abstract 1
- 101710112752 Cytotoxin Proteins 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 208000008589 Obesity Diseases 0.000 abstract 1
- 235000019647 acidic taste Nutrition 0.000 abstract 1
- 230000002378 acidificating effect Effects 0.000 abstract 1
- 239000011324 bead Substances 0.000 abstract 1
- 235000019658 bitter taste Nutrition 0.000 abstract 1
- 230000000903 blocking effect Effects 0.000 abstract 1
- 230000003822 cell turnover Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 208000012696 congenital leptin deficiency Diseases 0.000 abstract 1
- 231100000599 cytotoxic agent Toxicity 0.000 abstract 1
- 239000002619 cytotoxin Substances 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 208000010643 digestive system disease Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000003623 enhancer Substances 0.000 abstract 1
- 230000002708 enhancing effect Effects 0.000 abstract 1
- 238000001943 fluorescence-activated cell sorting Methods 0.000 abstract 1
- 230000006870 function Effects 0.000 abstract 1
- 210000001035 gastrointestinal tract Anatomy 0.000 abstract 1
- 230000003832 immune regulation Effects 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 238000002372 labelling Methods 0.000 abstract 1
- 230000002503 metabolic effect Effects 0.000 abstract 1
- 230000004060 metabolic process Effects 0.000 abstract 1
- 208000001022 morbid obesity Diseases 0.000 abstract 1
- 108020003175 receptors Proteins 0.000 abstract 1
- 238000010187 selection method Methods 0.000 abstract 1
- 230000014860 sensory perception of taste Effects 0.000 abstract 1
- 210000000130 stem cell Anatomy 0.000 abstract 1
- 235000019605 sweet taste sensations Nutrition 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
- 235000019607 umami taste sensations Nutrition 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1072—Differential gene expression library synthesis, e.g. subtracted libraries, differential screening
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1086—Preparation or screening of expression libraries, e.g. reporter assays
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Immunology (AREA)
- Plant Pathology (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US81176306P | 2006-06-08 | 2006-06-08 | |
| US83119906P | 2006-07-17 | 2006-07-17 | |
| US84899506P | 2006-10-04 | 2006-10-04 | |
| US86617806P | 2006-11-16 | 2006-11-16 | |
| PCT/US2007/013502 WO2007146120A2 (en) | 2006-06-08 | 2007-06-08 | Rationale, methods, and assays for identifying novel taste cell genes and salty taste receptor targets and assays using these identified genes or gene products |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20084993L true NO20084993L (no) | 2008-11-28 |
Family
ID=38832404
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20084993A NO20084993L (no) | 2006-06-08 | 2008-11-28 | Forklaring, metoder, og prover for identifisering av nye smakscelle-gener og saltsmak-reseptor mal og prover som anvender disse identifiserte genene eller gen-produktene |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20080261824A1 (enExample) |
| EP (1) | EP2024518A4 (enExample) |
| JP (1) | JP2009539377A (enExample) |
| AU (1) | AU2007258511A1 (enExample) |
| CA (1) | CA2654552A1 (enExample) |
| IL (1) | IL195205A0 (enExample) |
| MX (1) | MX2008015314A (enExample) |
| NO (1) | NO20084993L (enExample) |
| TW (1) | TW200813232A (enExample) |
| WO (1) | WO2007146120A2 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10078087B2 (en) | 2001-05-01 | 2018-09-18 | Senomyx, Inc. | Assays and enhancers of the human delta ENaC sodium channel |
| CA2530497A1 (en) | 2003-07-10 | 2005-02-17 | Senomyx, Inc. | Improved electrophysiological assays using oocytes that express human enac and the use of phenamil to improve the effect of enac enhancers in assays using membrane potential reporting dyes |
| CA2666962C (en) * | 2006-10-19 | 2015-12-08 | Monell Chemical Senses Center | Human salty taste receptor and methods of modulating salty taste perception |
| US20090210953A1 (en) * | 2007-06-08 | 2009-08-20 | Bryan Moyer | Identification of TRPML3 (MCOLN3) as a salty taste receptor and use in assays for identifying taste (salty) modulators and/or therapeutics that modulate sodium transport, absorption or excretion and/or aldosterone, and/or vasopressin production or release |
| EP2164976A4 (en) | 2007-06-08 | 2010-06-30 | Senomyx Inc | THEORETICAL BASIS, METHODS AND TESTS FOR IDENTIFYING FLAVOR SPECIES OF HUMAN AND NON-MUSCLE PRIMATES AND USE THEREOF IN TASTE MODULATOR AND THERAPEUTIC SCREENING TESTS |
| WO2010065863A2 (en) * | 2008-12-05 | 2010-06-10 | Senomyx, Inc. | Assays for identifying genes encoding salty taste receptors and modulators |
| WO2010144773A1 (en) * | 2009-06-12 | 2010-12-16 | Monell Chemical Senses Center | Stg promoter and its use as a marker for taste and oocyte cells |
| JP5206882B2 (ja) | 2009-09-29 | 2013-06-12 | 味の素株式会社 | 塩味調節物質のスクリーニング方法 |
| JP5627479B2 (ja) * | 2011-01-24 | 2014-11-19 | 日清食品ホールディングス株式会社 | Ｓｋｎ−１ａ／ｉノックアウトマウスを用いた味蕾細胞マーカー分子の探索方法 |
| EP3285795B1 (en) * | 2015-04-22 | 2022-11-16 | Cedars-Sinai Medical Center | Enterically delivered bitter oligopeptides for the treatment for type 2 diabetes and obesity |
| JP7357282B2 (ja) * | 2017-12-28 | 2023-10-06 | 日清食品ホールディングス株式会社 | 塩味受容体を用いた塩味増強剤のスクリーニング方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5750339A (en) * | 1994-11-30 | 1998-05-12 | Thomas Jefferson University | Methods for identifying fetal cells |
| US7041448B2 (en) * | 2000-08-18 | 2006-05-09 | The ML4 Foundation | Gene encoding a new TRP channel is mutated in mucolipidosis IV |
| US20020164645A1 (en) * | 2000-12-29 | 2002-11-07 | The Regents Of The University Of California | Assays for taste receptor cell specific ion channel |
| TW201022287A (en) * | 2001-01-03 | 2010-06-16 | Senomyx Inc | T1R taste receptors and genes encoding same |
| US7368285B2 (en) * | 2001-03-07 | 2008-05-06 | Senomyx, Inc. | Heteromeric umami T1R1/T1R3 taste receptors and isolated cells that express same |
| WO2002086079A2 (en) * | 2001-04-20 | 2002-10-31 | Mount Sinai School Of Medicine | T1r3 a novel taste receptor |
| AU2002320294B2 (en) * | 2001-07-03 | 2009-01-15 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Mammalian sweet and amino acid heterodimeric taste receptors |
| DE10155130A1 (de) * | 2001-11-12 | 2003-05-22 | Max Delbrueck Centrum | Verfahren zur Isolierung von Neuronen |
| US20050266442A1 (en) * | 2004-03-25 | 2005-12-01 | Rachel Squillace | Immortalized human Tuberous Sclerosis null angiomyolipoma cell and method of use thereof |
-
2007
- 2007-06-08 WO PCT/US2007/013502 patent/WO2007146120A2/en not_active Ceased
- 2007-06-08 JP JP2009514392A patent/JP2009539377A/ja not_active Abandoned
- 2007-06-08 EP EP07809397A patent/EP2024518A4/en not_active Withdrawn
- 2007-06-08 US US11/808,356 patent/US20080261824A1/en not_active Abandoned
- 2007-06-08 AU AU2007258511A patent/AU2007258511A1/en not_active Abandoned
- 2007-06-08 CA CA002654552A patent/CA2654552A1/en not_active Abandoned
- 2007-06-08 MX MX2008015314A patent/MX2008015314A/es unknown
- 2007-06-08 TW TW096120717A patent/TW200813232A/zh unknown
-
2008
- 2008-11-10 IL IL195205A patent/IL195205A0/en unknown
- 2008-11-28 NO NO20084993A patent/NO20084993L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| IL195205A0 (en) | 2009-08-03 |
| WO2007146120A3 (en) | 2008-12-04 |
| US20080261824A1 (en) | 2008-10-23 |
| MX2008015314A (es) | 2008-12-12 |
| AU2007258511A1 (en) | 2007-12-21 |
| TW200813232A (en) | 2008-03-16 |
| EP2024518A4 (en) | 2010-05-26 |
| CA2654552A1 (en) | 2007-12-21 |
| EP2024518A2 (en) | 2009-02-18 |
| WO2007146120A2 (en) | 2007-12-21 |
| JP2009539377A (ja) | 2009-11-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |