NO20083838L - Anvendelse av KCNQ-apnere for a behandle eller redusere symptomene pa schizofreni - Google Patents
Anvendelse av KCNQ-apnere for a behandle eller redusere symptomene pa schizofreniInfo
- Publication number
- NO20083838L NO20083838L NO20083838A NO20083838A NO20083838L NO 20083838 L NO20083838 L NO 20083838L NO 20083838 A NO20083838 A NO 20083838A NO 20083838 A NO20083838 A NO 20083838A NO 20083838 L NO20083838 L NO 20083838L
- Authority
- NO
- Norway
- Prior art keywords
- symptoms
- schizophrenia
- relates
- treat
- reduce
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/136—Amines having aromatic rings, e.g. ketamine, nortriptyline having the amino group directly attached to the aromatic ring, e.g. benzeneamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Oppfinnelsen vedrører en ny fremgangsmåte for behandling eller reduksjon av symptomer på schizofreni, der nevnte fremgangsmåte omfatter å administrere til en vert som trenger det en effektiv mengde av en forbindelse i stand til å selektivt øke ionestrømmen gjennom KCNQ-kaliumkanaler. Videre vedrører oppfinnelsen anvendelsen av selektive KCNQ-kaliumkanalåpnere for fremstillingen av en farmasøytisk sammensetning for behandling eller reduksjon av symptomer på schizofreni og beslektede symptomer, lidelser og sykdommer. Videre vedrører oppfinnelsen en fremgangsmåte for screening av en forbindelse, som er en selektiv KCNQ-kaliumkanalåpner og som er i stand til å ha et antipsykotisk potensial.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US77130406P | 2006-02-07 | 2006-02-07 | |
DKPA200600175 | 2006-02-07 | ||
PCT/DK2007/050013 WO2007090409A1 (en) | 2006-02-07 | 2007-02-02 | Use of kcnq-openers for threating or reducing the symptoms of schizophrenia |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20083838L true NO20083838L (no) | 2008-10-31 |
Family
ID=38055396
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20083838A NO20083838L (no) | 2006-02-07 | 2008-09-05 | Anvendelse av KCNQ-apnere for a behandle eller redusere symptomene pa schizofreni |
Country Status (16)
Country | Link |
---|---|
US (1) | US20090118285A1 (no) |
EP (2) | EP1983974A1 (no) |
JP (1) | JP2009525993A (no) |
KR (1) | KR20080096659A (no) |
CN (1) | CN101378742B (no) |
AR (1) | AR059319A1 (no) |
AU (1) | AU2007214128B2 (no) |
BR (1) | BRPI0707495A2 (no) |
CA (1) | CA2641564C (no) |
EA (1) | EA017915B1 (no) |
IL (1) | IL192745A0 (no) |
MX (1) | MX2008009655A (no) |
NO (1) | NO20083838L (no) |
NZ (1) | NZ569517A (no) |
TW (1) | TWI453013B (no) |
WO (1) | WO2007090409A1 (no) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2011513196A (ja) * | 2007-08-01 | 2011-04-28 | ハー・ルンドベック・アクチエゼルスカベット | ドーパミン作動系が破壊された障害もしくは状態の症状を軽減するためまたはその障害もしくは状態を処置するためのkcnqカリウムチャネル開口薬の使用 |
CA2804165C (en) | 2010-07-08 | 2015-02-24 | Pfizer Inc. | Piperidinyl pyrimidine amides as kv7 potassium channel openers |
US10526280B2 (en) | 2014-11-13 | 2020-01-07 | University of Pittsburgh—of the Commonwealth System of Higher Education | (2-amino-4-(arylamino)phenyl carbamates |
US10590067B2 (en) | 2018-02-20 | 2020-03-17 | H. Lundbeck A/S | Alcohol derivatives of carboxamides as Kv7 potassium channel openers |
MD3755684T2 (ro) | 2018-02-20 | 2023-11-30 | H Lundbeck As | Derivați de alcool ca deschizători ai canalelor de potasiu Kv7 |
WO2019203951A1 (en) | 2018-04-20 | 2019-10-24 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Selective potassium channel agonists |
JP2022543230A (ja) | 2019-08-02 | 2022-10-11 | ハー・ルンドベック・アクチエゼルスカベット | てんかん又はてんかん発作において使用するためのKv7カリウムチャネル開口薬としてのアルコール誘導体 |
AR119521A1 (es) | 2019-08-02 | 2021-12-22 | H Lundbeck As | DERIVADOS DE ALCOHOL COMO ABRIDORES DEL CANAL DE POTASIO Kv7 |
CN114206830A (zh) | 2019-08-02 | 2022-03-18 | H.隆德贝克有限公司 | 作为Kv7钾通道开放剂的醇衍生物 |
CA3159876A1 (en) * | 2019-12-06 | 2021-06-10 | James MURROUGH | Method of treatment with kcnq channel openers |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4200259A1 (de) * | 1992-01-08 | 1993-07-15 | Asta Medica Ag | Neue 1,2,4-triaminobenzol-derivate und verfahren zu deren herstellung |
JP4294142B2 (ja) | 1999-02-02 | 2009-07-08 | 株式会社日立製作所 | ディスクサブシステム |
GB9915414D0 (en) * | 1999-07-01 | 1999-09-01 | Glaxo Group Ltd | Medical use |
US6472165B1 (en) * | 1999-08-03 | 2002-10-29 | Arzneimittelwerk Dresden Gmbh | Modulatory binding site in potassium channels for screening and finding new active ingredients |
US6495550B2 (en) * | 1999-08-04 | 2002-12-17 | Icagen, Inc. | Pyridine-substituted benzanilides as potassium ion channel openers |
US6469042B1 (en) * | 2001-02-20 | 2002-10-22 | Bristol-Myers Squibb Company | Fluoro oxindole derivatives as modulators if KCNQ potassium channels |
EP1441722A2 (en) * | 2001-02-20 | 2004-08-04 | Bristol-Myers Squibb Company | Modulators of kcnq potassium channels and use thereof in treating migraine and mechanistically related diseases |
US6831080B2 (en) * | 2001-05-31 | 2004-12-14 | Bristol-Myers Squibb Company | Cinnamide derivatives as KCNQ potassium channel modulators |
DE10228103A1 (de) | 2002-06-24 | 2004-01-15 | Bayer Cropscience Ag | Fungizide Wirkstoffkombinationen |
WO2004047744A2 (en) * | 2002-11-22 | 2004-06-10 | Bristol-Myers Squibb Company | 3-heterocyclic benzylamide derivatives as potassium channel openers |
US6933308B2 (en) * | 2002-12-20 | 2005-08-23 | Bristol-Myers Squibb Company | Aminoalkyl thiazole derivatives as KCNQ modulators |
DK1578740T3 (da) * | 2002-12-27 | 2007-07-30 | Lundbeck & Co As H | 1,2,4-triaminobenzenderivater, der er egnede til behandling af lidelser i centralnervesystemet |
JP2006523196A (ja) * | 2003-03-11 | 2006-10-12 | ニューロサーチ、アクティーゼルスカブ | 新規kcnqチャネルを調節する化合物及びその医薬用途 |
AU2004220424B2 (en) * | 2003-03-14 | 2009-01-22 | H. Lundbeck A/S | Substituted aniline derivatives |
EP1613303A1 (en) | 2003-03-21 | 2006-01-11 | H. Lundbeck A/S | Substituted p-diaminobenzene derivatives |
US20060264496A1 (en) * | 2003-04-25 | 2006-11-23 | H. Lundbeck A/S | Substituted indoline and indole derivatives |
US7563748B2 (en) | 2003-06-23 | 2009-07-21 | Cognis Ip Management Gmbh | Alcohol alkoxylate carriers for pesticide active ingredients |
US7223768B2 (en) * | 2003-09-10 | 2007-05-29 | Icagen, Inc. | Fused ring heterocycles as potassium channel modulators |
JP4642034B2 (ja) * | 2004-02-20 | 2011-03-02 | ナショナル センター フォー バイオロジカル サイエンシズ | 新規カリウムチャネルモジュレータペプチド |
TWI349666B (en) * | 2004-03-12 | 2011-10-01 | Lundbeck & Co As H | Substituted morpholine and thiomorpholine derivatives |
WO2006000020A1 (en) | 2004-06-29 | 2006-01-05 | European Nickel Plc | Improved leaching of base metals |
UA89503C2 (uk) * | 2004-09-13 | 2010-02-10 | Х. Луннбек А/С | Заміщені похідні аніліну |
EP1861394A1 (en) * | 2005-03-03 | 2007-12-05 | H.Lundbeck A/S | Substituted pyridine derivatives |
DE602006018447D1 (de) * | 2005-04-13 | 2011-01-05 | Neuraxon Inc | Substituierte indolverbindungen mit nos-hemmender aktivität |
-
2007
- 2007-02-02 CA CA2641564A patent/CA2641564C/en not_active Expired - Fee Related
- 2007-02-02 EP EP07702527A patent/EP1983974A1/en not_active Withdrawn
- 2007-02-02 BR BRPI0707495-6A patent/BRPI0707495A2/pt not_active IP Right Cessation
- 2007-02-02 JP JP2008553621A patent/JP2009525993A/ja not_active Ceased
- 2007-02-02 EA EA200870232A patent/EA017915B1/ru not_active IP Right Cessation
- 2007-02-02 MX MX2008009655A patent/MX2008009655A/es active IP Right Grant
- 2007-02-02 EP EP12190206A patent/EP2554162A1/en not_active Withdrawn
- 2007-02-02 AU AU2007214128A patent/AU2007214128B2/en not_active Ceased
- 2007-02-02 US US12/278,394 patent/US20090118285A1/en not_active Abandoned
- 2007-02-02 WO PCT/DK2007/050013 patent/WO2007090409A1/en active Application Filing
- 2007-02-02 TW TW096103826A patent/TWI453013B/zh not_active IP Right Cessation
- 2007-02-02 CN CN2007800046484A patent/CN101378742B/zh not_active Expired - Fee Related
- 2007-02-02 KR KR1020087019396A patent/KR20080096659A/ko not_active Application Discontinuation
- 2007-02-02 NZ NZ569517A patent/NZ569517A/en not_active IP Right Cessation
- 2007-02-05 AR ARP070100469A patent/AR059319A1/es not_active Application Discontinuation
-
2008
- 2008-07-10 IL IL192745A patent/IL192745A0/en unknown
- 2008-09-05 NO NO20083838A patent/NO20083838L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO2007090409A1 (en) | 2007-08-16 |
TWI453013B (zh) | 2014-09-21 |
NZ569517A (en) | 2011-07-29 |
EP1983974A1 (en) | 2008-10-29 |
MX2008009655A (es) | 2008-09-03 |
EA017915B1 (ru) | 2013-04-30 |
AR059319A1 (es) | 2008-03-26 |
CN101378742A (zh) | 2009-03-04 |
US20090118285A1 (en) | 2009-05-07 |
CA2641564C (en) | 2012-06-12 |
AU2007214128B2 (en) | 2012-05-17 |
CN101378742B (zh) | 2013-07-10 |
IL192745A0 (en) | 2009-02-11 |
BRPI0707495A2 (pt) | 2011-05-03 |
EA200870232A1 (ru) | 2009-02-27 |
TW200808296A (en) | 2008-02-16 |
JP2009525993A (ja) | 2009-07-16 |
AU2007214128A1 (en) | 2007-08-16 |
CA2641564A1 (en) | 2007-08-16 |
EP2554162A1 (en) | 2013-02-06 |
KR20080096659A (ko) | 2008-10-31 |
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Legal Events
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FC2A | Withdrawal, rejection or dismissal of laid open patent application |