NO20083378L - Syntese av glukagon-lignende peptid - Google Patents

Syntese av glukagon-lignende peptid

Info

Publication number
NO20083378L
NO20083378L NO20083378A NO20083378A NO20083378L NO 20083378 L NO20083378 L NO 20083378L NO 20083378 A NO20083378 A NO 20083378A NO 20083378 A NO20083378 A NO 20083378A NO 20083378 L NO20083378 L NO 20083378L
Authority
NO
Norway
Prior art keywords
peptide
glucagon
synthesis
devised
new method
Prior art date
Application number
NO20083378A
Other languages
English (en)
Inventor
Matthieu Giraud
Oleg Werbitzky
Stephane Varray
Carsten Meininghaus
Original Assignee
Lonza Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza Ag filed Critical Lonza Ag
Publication of NO20083378L publication Critical patent/NO20083378L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/10—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using coupling agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

En ny metode for syntetisering av GLP-1 peptid er utformet.
NO20083378A 2006-02-08 2008-08-04 Syntese av glukagon-lignende peptid NO20083378L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06002537 2006-02-08
PCT/EP2007/000198 WO2007090496A1 (en) 2006-02-08 2007-01-11 Synthesis of glucagon-like peptide

Publications (1)

Publication Number Publication Date
NO20083378L true NO20083378L (no) 2008-10-31

Family

ID=37697824

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20083378A NO20083378L (no) 2006-02-08 2008-08-04 Syntese av glukagon-lignende peptid

Country Status (19)

Country Link
US (2) US8445433B2 (no)
EP (1) EP1987052B1 (no)
JP (1) JP5199126B2 (no)
KR (1) KR101297942B1 (no)
CN (1) CN101379075B (no)
AT (1) ATE507235T1 (no)
AU (1) AU2007214088B2 (no)
BR (1) BRPI0707599A2 (no)
CA (1) CA2641053A1 (no)
DE (1) DE602007014184D1 (no)
DK (1) DK1987052T3 (no)
ES (1) ES2364982T3 (no)
IL (1) IL193134A (no)
MX (1) MX2008010136A (no)
NO (1) NO20083378L (no)
PT (1) PT1987052E (no)
TW (1) TWI404724B (no)
WO (1) WO2007090496A1 (no)
ZA (1) ZA200806690B (no)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101835794A (zh) 2007-10-27 2010-09-15 霍夫曼-拉罗奇有限公司 使用固相和溶液相组合技术的促胰岛素肽合成法
AU2008334783A1 (en) * 2007-12-11 2009-06-18 F. Hoffmann-La Roche Ag Insulinotropic peptide synthesis using solid and solution phase combination techniques
JP2012525348A (ja) * 2009-05-01 2012-10-22 エフ．ホフマン−ラ ロシュ アーゲー 固相及び溶液相の組み合わせ技術を用いたインスリン分泌促進ペプチド合成
CN102250235A (zh) * 2011-06-23 2011-11-23 成都圣诺科技发展有限公司 奈西立肽的制备方法
GB201310921D0 (en) 2013-06-19 2013-07-31 Chemical & Biopharmaceutical Lab Of Patras S A Peptide-resin conjugate and use thereof
WO2015086686A2 (en) * 2013-12-13 2015-06-18 Medimmune Limited Protease resistant peptides
CN104017064B (zh) * 2014-06-13 2016-08-24 杭州阿诺生物医药科技股份有限公司 一种制备特立帕肽的方法
GR20140100479A (el) 2014-09-23 2016-05-05 Novetide, Ltd., Συνθεση λιραγλουτιδης
CN104356221B (zh) * 2014-10-24 2018-06-26 杭州阿诺生物医药科技股份有限公司 一种制备培西加南的方法
CN109641946A (zh) * 2016-03-23 2019-04-16 巴切姆股份公司 胰高血糖素样肽的制备方法
US20200317721A1 (en) 2017-10-04 2020-10-08 Chemical & Biopharmaceutical Laboratories Of Patras S.A. A process for preparing a glucagon-like peptide
WO2020127476A1 (en) 2018-12-19 2020-06-25 Krka, D.D., Novo Mesto Pharmaceutical composition comprising glp-1 analogue
WO2020190757A1 (en) 2019-03-15 2020-09-24 Novetide Ltd. Improved processes for the preparation of semaglutide
WO2021123228A1 (en) 2019-12-18 2021-06-24 Krka, D.D., Novo Mesto Pharmaceutical composition comprising glp-1 analogue
CN116925237A (zh) 2019-12-31 2023-10-24 北京质肽生物医药科技有限公司 Glp-1和gdf15的融合蛋白以及其缀合物
EP4222176A4 (en) 2020-09-30 2024-02-28 Beijing QL Biopharmaceutical Co., Ltd. POLYPEPTIDE CONJUGATES AND METHODS OF USE
CN114249808A (zh) * 2021-12-27 2022-03-29 杭州诺泰澳赛诺医药技术开发有限公司 一种Cagrilintide的合成方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3421303A1 (de) 1984-06-08 1985-12-12 Hoechst Ag, 6230 Frankfurt Salze aus 3-hydroxy-4-oxo-3,4-dihydro-1,2,3-benzotriazin und amino-verbindungen
US5574008A (en) 1994-08-30 1996-11-12 Eli Lilly And Company Biologically active fragments of glucagon-like insulinotropic peptide
US6268343B1 (en) * 1996-08-30 2001-07-31 Novo Nordisk A/S Derivatives of GLP-1 analogs
CA2501421A1 (en) * 1999-05-17 2000-11-23 Conjuchem Inc. Long lasting exendin-4
ATE264870T1 (de) 2000-01-27 2004-05-15 Lilly Co Eli Verfahren zur lösung von glucagon-ähnlichen peptid-1 (glp-1) verbindungen
US6969702B2 (en) * 2002-11-20 2005-11-29 Neuronova Ab Compounds and methods for increasing neurogenesis
BRPI0414539B8 (pt) 2003-09-19 2021-05-25 Novo Nordisk As composto, composição farmacêutica, e, uso de um composto
CA2596926A1 (en) * 2005-03-18 2006-09-21 Novo Nordisk A/S Extended glp-1 compounds

Also Published As

Publication number Publication date
EP1987052B1 (en) 2011-04-27
PT1987052E (pt) 2011-07-25
DK1987052T3 (da) 2011-08-15
IL193134A (en) 2014-06-30
KR20080100448A (ko) 2008-11-18
ES2364982T3 (es) 2011-09-20
KR101297942B1 (ko) 2013-08-19
US8445433B2 (en) 2013-05-21
US9040480B2 (en) 2015-05-26
TW200745157A (en) 2007-12-16
TWI404724B (zh) 2013-08-11
JP2009525997A (ja) 2009-07-16
AU2007214088A1 (en) 2007-08-16
MX2008010136A (es) 2008-12-19
US20130324699A1 (en) 2013-12-05
EP1987052A1 (en) 2008-11-05
IL193134A0 (en) 2009-02-11
CN101379075A (zh) 2009-03-04
CN101379075B (zh) 2013-05-15
AU2007214088B2 (en) 2012-03-22
JP5199126B2 (ja) 2013-05-15
DE602007014184D1 (de) 2011-06-09
BRPI0707599A2 (pt) 2011-05-10
US20090292106A1 (en) 2009-11-26
ATE507235T1 (de) 2011-05-15
CA2641053A1 (en) 2007-08-16
WO2007090496A1 (en) 2007-08-16
ZA200806690B (en) 2009-07-29

Similar Documents

Publication Publication Date Title
NO20083378L (no) Syntese av glukagon-lignende peptid
MX2010003599A (es) Intermediarios y metodos para la sintesis de analogos de halicondrina b.
EA200601795A1 (ru) Синтез эфиров бороновой кислоты и кислотных соединений
MX2009008271A (es) Procesos e intermediarios para la preparacion de un inhibidor de proteasa macrocilico del vhc.
CY1112495T1 (el) Κυτταροτοξικοι παραγοντες που περιλαμβανουν νεα παραγωγα τομαϋμυκινης
EA201101015A1 (ru) Способ получения бивалирудина
ATE480561T1 (de) Verfahren zur festphasen-peptidsynthese
HRP20080554B1 (hr) Postupak priprave inhibitora proteaze hiv
TW200728310A (en) Process for the preparation of ferri-succinylcasein
EA200970373A1 (ru) АНТИДЕПРЕССАНТ, НЕЙРОПРОТЕКТОР, ИНГИБИТОР ОТЛОЖЕНИЙ β-АМИЛОИДА ИЛИ СРЕДСТВО, ЗАМЕДЛЯЮЩЕЕ СТАРЕНИЯ, СОДЕРЖАЩИЕ ГЕТЕРОЦИКЛИЧЕСКОЕ СОЕДИНЕНИЕ КОНКРЕТНОЙ СТРУКТУРЫ
ATE517869T1 (de) Herstellung substituierter morphinan-6-one und salzen und zwischenprodukten davon
EA200801884A1 (ru) Новый способ синтеза ранелата стронция и его гидратов
SV2011003923A (es) 3-aminociclopentancarboxamidas
GEP20146019B (en) Novel method of synthesizing ivabradine and pharmaceutically acceptable acid-additive salts thereof
IS8338A (is) Framleiðsla sómatóstatínpeptíða
HK1079513A1 (en) Process for preparing intermediates
ATE501127T1 (de) Neue cysteinproteasehemmer und ihre therapeutische anwendung
TW200825088A (en) Processes for preparing intermediates of pemetrexed
CY1112443T1 (el) Νεα θεραπευτικη χρηση για τη θεραπεια των λευχαιμιων
ES2530436T3 (es) Combinación
DK1856125T3 (da) Syntese af proteasehæmmerforstadie
MX2010011055A (es) Derivados peptidicos de opiorfina como potentes inhibidores de ectopeptidasas degradadoras de encefalinas.
WO2007099227A3 (fr) Utilisation de la proteine a homeodomaine engrailed comme anxiolytique
TW200628487A (en) On-resin peptide cyclisation
EA200900982A1 (ru) Новый способ синтеза прамипексола и его фармацевтически приемлемых солей

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application