NO20082365L - Ny metode for fremstilling av 5-amino-3H-tiazolo[4,5-D]pyrimidin-2-on - Google Patents

Ny metode for fremstilling av 5-amino-3H-tiazolo[4,5-D]pyrimidin-2-on

Info

Publication number
NO20082365L
NO20082365L NO20082365A NO20082365A NO20082365L NO 20082365 L NO20082365 L NO 20082365L NO 20082365 A NO20082365 A NO 20082365A NO 20082365 A NO20082365 A NO 20082365A NO 20082365 L NO20082365 L NO 20082365L
Authority
NO
Norway
Prior art keywords
preparation
thiazolo
pyrimidin
amino
new method
Prior art date
Application number
NO20082365A
Other languages
English (en)
Inventor
Stephen E Webber
Tingmin Wang
John S Ng
Original Assignee
Anadys Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anadys Pharmaceuticals Inc filed Critical Anadys Pharmaceuticals Inc
Publication of NO20082365L publication Critical patent/NO20082365L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Foreliggende oppfinnelse angår en fremgangsmåte for fremstilling av tittelforbindelsen, 5-amino-3H-tiazolo[4,5-d]pyrimidin-2-on, som er et anvendelig mellomprodukt ved fremstilling av visse tiazolo[4,5-d]pyrimidin-nukleosider, som kan ha nytte som immunmodulerende midler.
NO20082365A 2005-11-21 2008-05-26 Ny metode for fremstilling av 5-amino-3H-tiazolo[4,5-D]pyrimidin-2-on NO20082365L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US73805505P 2005-11-21 2005-11-21
PCT/US2006/061111 WO2007062355A2 (en) 2005-11-21 2006-11-20 PROCESS FOR THE PREPARATION OF 5-AMINO-3H- THIAZOLO [4 , 5 -d] PYRIMIDIN- 2 -ONE

Publications (1)

Publication Number Publication Date
NO20082365L true NO20082365L (no) 2008-08-18

Family

ID=37908057

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20082365A NO20082365L (no) 2005-11-21 2008-05-26 Ny metode for fremstilling av 5-amino-3H-tiazolo[4,5-D]pyrimidin-2-on

Country Status (18)

Country Link
US (1) US7781581B2 (no)
EP (1) EP1973920B1 (no)
JP (1) JP5117391B2 (no)
KR (1) KR20080090400A (no)
CN (1) CN101365705A (no)
AR (1) AR058210A1 (no)
AT (1) ATE474842T1 (no)
AU (1) AU2006318260B2 (no)
BR (1) BRPI0618789A2 (no)
CA (1) CA2630463C (no)
DE (1) DE602006015700D1 (no)
EA (1) EA200801404A1 (no)
ES (1) ES2345904T3 (no)
IL (1) IL191568A0 (no)
NO (1) NO20082365L (no)
SG (1) SG152296A1 (no)
TW (1) TWI383987B (no)
WO (1) WO2007062355A2 (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2008016518A (es) 2006-06-22 2009-01-19 Anadys Pharmaceuticals Inc Profarmacos de 5-amino-3-(3'-desoxi-beta-d-ribofuranosil)-tiazolo[ 4,5-d]pirimidin-2,7-dion.
JPWO2012102366A1 (ja) * 2011-01-28 2014-06-30 日本たばこ産業株式会社 新規ピペラジン化合物の製造方法
CN103012284A (zh) * 2012-12-26 2013-04-03 无锡捷化医药科技有限公司 一种2-氨基-5-溴嘧啶类化合物的制备方法
WO2016091698A1 (en) 2014-12-08 2016-06-16 F. Hoffmann-La Roche Ag 3-substituted 5-amino-6h-thiazolo[4,5-d]pyrimidine-2,7-dione compounds for the treatment and prophylaxis of virus infection
WO2018127525A1 (en) 2017-01-06 2018-07-12 F. Hoffmann-La Roche Ag PROCESS FOR THE PREPARATION OF 3-SUBSTITUTED 5-AMINO-6H-THIAZOLO[4,5-d]PYRIMIDINE-2,7-DIONE COMPOUNDS
CN111635368B (zh) * 2020-06-12 2021-06-29 东莞市东阳光仿制药研发有限公司 一种胺化合物的制备方法

Family Cites Families (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4643992A (en) 1982-11-09 1987-02-17 Scripps Clinic And Research Foundation Modulation of animal cellular responses with compositions containing 8-substituted guanine derivatives
US4539205A (en) 1982-11-09 1985-09-03 Scripps Clinic And Research Foundation Modulation of animal cellular responses with compositions containing 8-substituted guanine derivatives
US4746651A (en) 1983-11-01 1988-05-24 Scripps Clinic And Research Foundation Antimicrobial chemotherapeutic potentiation using substituted nucleoside derivatives
US5166141A (en) 1983-11-01 1992-11-24 Scripps Clinic And Research Foundation Immunostimulating 7-deaza-7-oxa- and 7-deaza-7-oxo-analogs of 8-substituted-guanine-9-(1'-beta-D-aldoglycosidyl) derivatives and methods of treating test animals
US5011828A (en) 1985-11-15 1991-04-30 Michael Goodman Immunostimulating guanine derivatives, compositions and methods
GB8712745D0 (en) 1987-05-30 1987-07-01 Wellcome Found Antiviral compounds
US5041426A (en) * 1987-12-21 1991-08-20 Brigham Young University Immune system enhancing 3-β-d-ribofuranosylthiazolo[4,5-d]pyridimine nucleosides and nucleotides
US4880784A (en) 1987-12-21 1989-11-14 Brigham Young University Antiviral methods utilizing ribofuranosylthiazolo[4,5-d]pyrimdine derivatives
US5041542A (en) 1988-06-03 1991-08-20 Nucleic Acid Research Institute Substituted pyrimido[5,4-d]pyrimidine nucleosides
GB9015914D0 (en) 1990-07-19 1990-09-05 Wellcome Found Heterocyclic compounds
US5248672A (en) 1990-11-01 1993-09-28 The Regents Of The University Of Michigan Polysubstituted benzimidazole nucleosides as antiviral agents
GB9105899D0 (en) 1991-03-20 1991-05-08 Wellcome Found Therapeutic nucleosides
WO1994007904A1 (en) 1992-10-01 1994-04-14 Mcneilab, Inc. Derivatives of 7,8-disubstituted guanosines
GB9301000D0 (en) 1993-01-20 1993-03-10 Glaxo Group Ltd Chemical compounds
US5395937A (en) 1993-01-29 1995-03-07 Minnesota Mining And Manufacturing Company Process for preparing quinoline amines
US5446045A (en) 1993-12-20 1995-08-29 Revankar; Ganapathi R. Antiviral guanine analogs
US5994321A (en) 1993-12-20 1999-11-30 Aronex Pharmaceuticals, Inc. Antiviral guanine analogs
US5496816A (en) 1994-03-14 1996-03-05 Merck & Co., Inc. Carbapenem antibacterial compounds, compositions containing such compounds and methods of treatment
EP0882727B9 (en) 1996-07-03 2005-06-15 Sumitomo Pharmaceuticals Company, Limited Novel purine derivatives
US6509320B1 (en) 1996-10-16 2003-01-21 Icn Pharmaceuticals, Inc. Purine L-nucleosides, analogs and uses thereof
CZ126799A3 (cs) 1996-10-16 1999-07-14 Icn Pharmaceuticals Purinové L-nukleosidy a jejich analogy a farmaceutické prostředky, které je obsahují
EP0938315B9 (en) 1996-10-25 2008-02-20 Minnesota Mining And Manufacturing Company Immune response modifier compounds for treatment of th2 mediated and related diseases
NZ504800A (en) 1997-11-28 2001-10-26 Sumitomo Pharma 6-Amino-9-benzyl-8-hydroxy-purine derivatives and interferon inducers, antiviral agents, anticancer agents and therapeutic agents for immunologic diseases thereof
TW572758B (en) 1997-12-22 2004-01-21 Sumitomo Pharma Type 2 helper T cell-selective immune response inhibitors comprising purine derivatives
AU3213699A (en) * 1998-04-03 1999-10-25 Du Pont Pharmaceuticals Company Thiazolo(4,5-d)pyrimidines and pyridines as corticotropin releasing factor (CRF)antagonists
US6444652B1 (en) 1998-08-10 2002-09-03 Novirio Pharmaceuticals Limited β-L-2'-deoxy-nucleosides for the treatment of hepatitis B
US6664260B2 (en) 2000-12-08 2003-12-16 3M Innovative Properties Company Heterocyclic ether substituted imidazoquinolines
US6664264B2 (en) 2000-12-08 2003-12-16 3M Innovative Properties Company Thioether substituted imidazoquinolines
US6545017B1 (en) 2000-12-08 2003-04-08 3M Innovative Properties Company Urea substituted imidazopyridines
US6667312B2 (en) 2000-12-08 2003-12-23 3M Innovative Properties Company Thioether substituted imidazoquinolines
US6545016B1 (en) 2000-12-08 2003-04-08 3M Innovative Properties Company Amide substituted imidazopyridines
US20020086871A1 (en) 2000-12-29 2002-07-04 O'neill Brian Thomas Pharmaceutical composition for the treatment of CNS and other disorders
ES2314042T3 (es) 2001-04-17 2009-03-16 Dainippon Sumitomo Pharma Co., Ltd. Derivados nuevos de adenina.
US7321033B2 (en) * 2001-11-27 2008-01-22 Anadys Pharmaceuticals, Inc. 3-B-D-ribofuranosylthiazolo [4,5-d] pyrimidine nucleosides and uses thereof
CN1300165C (zh) 2001-11-27 2007-02-14 安那迪斯药品股份有限公司 3－β－呋喃核糖基噻唑并[4,5－d]嘧啶核苷及其应用
US20040063658A1 (en) 2002-05-06 2004-04-01 Roberts Christopher Don Nucleoside derivatives for treating hepatitis C virus infection
US7196090B2 (en) * 2002-07-25 2007-03-27 Warner-Lambert Company Kinase inhibitors
WO2005016235A2 (en) 2003-04-14 2005-02-24 The Regents Of The University Of California Combined use of impdh inhibitors with toll-like receptor agonists
US7585878B2 (en) * 2003-06-12 2009-09-08 Astellas Pharma Inc. Benzamide derivative or salt thereof
EA200600540A1 (ru) 2003-09-05 2006-08-25 Анадис Фармасьютикалз, Инк. Введение лигандов tlr7 и их пролекарств для лечения инфекции вируса гепатита с
CA2555914A1 (en) * 2004-03-08 2005-09-22 Amgen Inc. Therapeutic modulation of ppar (gamma) activity
MX2007004217A (es) 2004-10-15 2007-06-11 Bayer Pharmaceuticals Corp Preparacion y uso de derivados de acido bifenil-4-il-carbonilamino para el tratamiento de obesidad.
SI1824482T1 (sl) * 2004-12-17 2014-06-30 Anadys Pharmaceuticals, Inc. 3,5-disubstituirane in 3,5,7-trisubstituiran-3H-oksazolo in 3H-tiazolo (4,5-d)pirimidin-2-onske spojine in njihova predzdravila
CN101233132A (zh) 2005-05-09 2008-07-30 海德拉生物科学公司 调节trpv3功能的化合物
MX2008016518A (es) 2006-06-22 2009-01-19 Anadys Pharmaceuticals Inc Profarmacos de 5-amino-3-(3'-desoxi-beta-d-ribofuranosil)-tiazolo[ 4,5-d]pirimidin-2,7-dion.
EP2040712B1 (en) 2006-07-18 2011-03-02 Anadys Pharmaceuticals, Inc. Carbonate and carbamate prodrugs of thiazolo [4,5-d] pyrimidines

Also Published As

Publication number Publication date
CN101365705A (zh) 2009-02-11
TWI383987B (zh) 2013-02-01
EA200801404A1 (ru) 2008-10-30
SG152296A1 (en) 2009-05-29
DE602006015700D1 (de) 2010-09-02
CA2630463A1 (en) 2007-05-31
AU2006318260A1 (en) 2007-05-31
AU2006318260B2 (en) 2012-05-17
JP5117391B2 (ja) 2013-01-16
US7781581B2 (en) 2010-08-24
BRPI0618789A2 (pt) 2016-08-30
EP1973920B1 (en) 2010-07-21
TW200736265A (en) 2007-10-01
CA2630463C (en) 2015-01-06
IL191568A0 (en) 2008-12-29
ATE474842T1 (de) 2010-08-15
WO2007062355A3 (en) 2007-07-26
KR20080090400A (ko) 2008-10-08
EP1973920A2 (en) 2008-10-01
AR058210A1 (es) 2008-01-23
ES2345904T3 (es) 2010-10-05
WO2007062355A2 (en) 2007-05-31
JP2009516709A (ja) 2009-04-23
US20070117979A1 (en) 2007-05-24

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