NO20080665L - Fag-fremvisning i a benytte kontraslasjonell translokasjon av fusjonspolypeptider - Google Patents
Fag-fremvisning i a benytte kontraslasjonell translokasjon av fusjonspolypeptiderInfo
- Publication number
- NO20080665L NO20080665L NO20080665A NO20080665A NO20080665L NO 20080665 L NO20080665 L NO 20080665L NO 20080665 A NO20080665 A NO 20080665A NO 20080665 A NO20080665 A NO 20080665A NO 20080665 L NO20080665 L NO 20080665L
- Authority
- NO
- Norway
- Prior art keywords
- phage
- translocation
- polypeptides
- phage display
- contralateral
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
- C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
- C12N15/625—DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/034—Fusion polypeptide containing a localisation/targetting motif containing a motif for targeting to the periplasmic space of Gram negative bacteria as a soluble protein, i.e. signal sequence should be cleaved
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
- C07K2319/43—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation containing a FLAG-tag
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/50—Fusion polypeptide containing protease site
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/735—Fusion polypeptide containing domain for protein-protein interaction containing a domain for self-assembly, e.g. a viral coat protein (includes phage display)
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/02—Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP05106236 | 2005-07-08 | ||
PCT/EP2006/063729 WO2007006665A1 (en) | 2005-07-08 | 2006-06-30 | Phage display using cotranslational translocation of fusion polypeptides |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20080665L true NO20080665L (no) | 2008-02-05 |
Family
ID=35063135
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20080665A NO20080665L (no) | 2005-07-08 | 2008-02-05 | Fag-fremvisning i a benytte kontraslasjonell translokasjon av fusjonspolypeptider |
Country Status (21)
Country | Link |
---|---|
US (2) | US8846577B2 (de) |
EP (1) | EP1902131B1 (de) |
JP (1) | JP5042218B2 (de) |
KR (1) | KR101268939B1 (de) |
CN (1) | CN101213299B (de) |
AT (1) | ATE448305T1 (de) |
AU (1) | AU2006268780B2 (de) |
BR (1) | BRPI0613593A2 (de) |
CA (1) | CA2614512C (de) |
DE (1) | DE602006010386D1 (de) |
DK (1) | DK1902131T3 (de) |
ES (1) | ES2335136T3 (de) |
HK (1) | HK1122839A1 (de) |
IL (1) | IL188518A (de) |
MX (1) | MX2008000345A (de) |
NO (1) | NO20080665L (de) |
NZ (1) | NZ564695A (de) |
PL (1) | PL1902131T3 (de) |
RU (1) | RU2412249C2 (de) |
WO (1) | WO2007006665A1 (de) |
ZA (1) | ZA200710687B (de) |
Families Citing this family (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1539235A2 (de) | 2002-07-01 | 2005-06-15 | Human Genome Sciences, Inc. | Spezifisch an reg iv bindende antikörper |
CA2677179C (en) * | 2007-01-31 | 2016-02-16 | Dow Global Technologies Inc. | Bacterial leader sequences for increased expression |
ES2836948T3 (es) | 2008-11-03 | 2021-06-28 | Molecular Partners Ag | Proteínas de unión que inhiben la interacción del receptor de VEGF-A |
GB0917647D0 (en) * | 2009-10-08 | 2009-11-25 | Glaxosmithkline Biolog Sa | Expression system |
ES2636971T3 (es) | 2009-11-05 | 2017-10-10 | F. Hoffmann-La Roche Ag | Procedimientos y composición para la secreción de polipéptidos heterógenos |
TWI510246B (zh) | 2010-04-30 | 2015-12-01 | Molecular Partners Ag | 抑制vegf-a受體交互作用的經修飾結合性蛋白質 |
PL2643349T3 (pl) | 2010-11-26 | 2020-03-31 | Molecular Partners Ag | Zaprojektowane białka z powtórzeniami wiążące się z albuminą surowicy |
ES2717657T3 (es) | 2011-02-15 | 2019-06-24 | Immunogen Inc | Métodos para la preparación de conjugados |
TW201302779A (zh) * | 2011-04-13 | 2013-01-16 | Glaxosmithkline Biolog Sa | 融合蛋白質及組合疫苗 |
US8722618B2 (en) | 2011-04-29 | 2014-05-13 | Janssen Biotech, Inc. | IL4/IL13 binding repeat proteins and uses |
BR112013032928A2 (pt) | 2011-06-21 | 2017-01-24 | Immunogen Inc | "derivados de maitansinoide com ligante de peptídeo e conjugados dos mesmos, composição farmacêutica que os compreende e uso dos mesmos" |
EP2867360B1 (de) | 2012-06-28 | 2019-05-08 | Molecular Partners AG | Von blutplättchen abstammender wachstumsfaktor (pdgf)-bindende, konstruierte ankyrin-repeat-proteine |
US9956341B2 (en) | 2012-07-03 | 2018-05-01 | Milestone Scientific, Inc. | Drug infusion with pressure sensing and non-continuous flow for identification of and injection into fluid-filled anatomic spaces |
EP2887965A1 (de) | 2012-08-22 | 2015-07-01 | ImmunoGen, Inc. | Zytotoxische benzodiazepin-derivate |
EP2738180A1 (de) | 2012-11-30 | 2014-06-04 | Molecular Partners AG | Bindeproteine mit mindestens zwei Bindedomänen gegen HER2 |
JP6494533B2 (ja) | 2013-02-28 | 2019-04-03 | イミュノジェン・インコーポレーテッド | 細胞結合剤及び細胞毒性剤としてのマイタンシノイドを含む複合体 |
JP6423804B2 (ja) | 2013-02-28 | 2018-11-14 | イミュノジェン・インコーポレーテッド | 細胞結合剤及び細胞毒性剤を含む複合体 |
US11453708B2 (en) | 2013-05-31 | 2022-09-27 | Molecular Partners Ag | Designed ankyrin repeat proteins binding to hepatocyte growth factor |
WO2014194030A2 (en) | 2013-05-31 | 2014-12-04 | Immunogen, Inc. | Conjugates comprising cell-binding agents and cytotoxic agents |
MA39746A (fr) | 2014-03-14 | 2021-04-28 | Hoffmann La Roche | Compositions de sécrétion de polypeptides hétérologues et procédés associés |
JP2017516458A (ja) | 2014-03-24 | 2017-06-22 | ジェネンテック, インコーポレイテッド | c−met拮抗剤による癌治療及びc−met拮抗剤のHGF発現との相関 |
US9381256B2 (en) | 2014-09-03 | 2016-07-05 | Immunogen, Inc. | Cytotoxic benzodiazepine derivatives |
MA54254A (fr) | 2014-09-03 | 2021-09-22 | Immunogen Inc | Dérivés de benzodiazépine cytotoxique |
KR102427117B1 (ko) | 2015-04-02 | 2022-07-29 | 몰리큘라 파트너스 아게 | 혈청 알부민에 대한 결합 특이성을 갖는 설계된 안키린 반복 도메인 |
US10220180B2 (en) | 2015-10-16 | 2019-03-05 | Milestone Scientific, Inc. | Method and apparatus for performing a peripheral nerve block |
WO2018045184A1 (en) | 2016-08-31 | 2018-03-08 | President And Fellows Of Harvard College | Engineered bacteria secreting therapeutic proteins and methods of use thereof |
MX2019003298A (es) | 2016-09-22 | 2019-09-26 | Molecular Partners Ag | Proteinas de union recombinantes y sus usos. |
US10632255B2 (en) | 2017-02-15 | 2020-04-28 | Milestone Scientific, Inc. | Drug infusion device |
CN116785450A (zh) | 2017-02-28 | 2023-09-22 | 伊缪诺金公司 | 具有自分解肽接头的类美登素衍生物和其缀合物 |
TW201839001A (zh) | 2017-04-20 | 2018-11-01 | 美商伊繆諾金公司 | 細胞毒性苯并二氮平衍生物及其綴合物 |
US11471595B2 (en) | 2017-05-04 | 2022-10-18 | Milestone Scientific, Inc. | Method and apparatus for performing a peripheral nerve block |
WO2019133652A1 (en) | 2017-12-28 | 2019-07-04 | Immunogen, Inc. | Benzodiazepine derivatives |
AU2020240310A1 (en) | 2019-03-21 | 2021-10-07 | Immunogen, Inc. | Methods of preparing cell-binding agent-drug conjugates |
CN113661172A (zh) | 2019-03-29 | 2021-11-16 | 伊缪诺金公司 | 用于抑制异常细胞生长或治疗增生性疾病的细胞毒性双苯并二氮杂䓬衍生物及其与细胞结合剂的缀合物 |
HRP20231619T1 (hr) | 2019-04-26 | 2024-04-26 | Immunogen, Inc. | Derivati kamptotecina |
US10646660B1 (en) | 2019-05-16 | 2020-05-12 | Milestone Scientific, Inc. | Device and method for identification of a target region |
KR20220113492A (ko) | 2019-12-11 | 2022-08-12 | 몰리큘라 파트너스 아게 | 변경된 표면 잔기를 갖는 설계된 안키린 반복 도메인 |
MX2022013945A (es) | 2020-05-06 | 2023-02-14 | Molecular Partners Ag | Nuevas proteinas de union a repeticiones de anquirina y sus usos. |
BR112023018293A2 (pt) | 2021-03-09 | 2023-10-31 | Molecular Partners Ag | Acopladores de célula t multiespecíficos à base de darpin |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999058655A2 (en) * | 1998-05-13 | 1999-11-18 | Diversys Limited | Phage display selection system for folded proteins |
-
2006
- 2006-06-30 NZ NZ564695A patent/NZ564695A/en not_active IP Right Cessation
- 2006-06-30 AU AU2006268780A patent/AU2006268780B2/en not_active Ceased
- 2006-06-30 RU RU2008104174/10A patent/RU2412249C2/ru not_active IP Right Cessation
- 2006-06-30 PL PL06763985T patent/PL1902131T3/pl unknown
- 2006-06-30 EP EP06763985A patent/EP1902131B1/de active Active
- 2006-06-30 AT AT06763985T patent/ATE448305T1/de active
- 2006-06-30 DE DE602006010386T patent/DE602006010386D1/de active Active
- 2006-06-30 CA CA2614512A patent/CA2614512C/en not_active Expired - Fee Related
- 2006-06-30 WO PCT/EP2006/063729 patent/WO2007006665A1/en active Application Filing
- 2006-06-30 JP JP2008519913A patent/JP5042218B2/ja not_active Expired - Fee Related
- 2006-06-30 CN CN2006800243863A patent/CN101213299B/zh not_active Expired - Fee Related
- 2006-06-30 MX MX2008000345A patent/MX2008000345A/es active IP Right Grant
- 2006-06-30 ES ES06763985T patent/ES2335136T3/es active Active
- 2006-06-30 DK DK06763985.6T patent/DK1902131T3/da active
- 2006-06-30 BR BRPI0613593-5A patent/BRPI0613593A2/pt not_active Application Discontinuation
- 2006-06-30 US US11/988,389 patent/US8846577B2/en active Active
-
2007
- 2007-12-07 ZA ZA200710687A patent/ZA200710687B/xx unknown
- 2007-12-31 IL IL188518A patent/IL188518A/en not_active IP Right Cessation
-
2008
- 2008-02-05 KR KR1020087003094A patent/KR101268939B1/ko not_active IP Right Cessation
- 2008-02-05 NO NO20080665A patent/NO20080665L/no not_active Application Discontinuation
- 2008-12-23 HK HK08113901.3A patent/HK1122839A1/xx not_active IP Right Cessation
-
2014
- 2014-08-26 US US14/468,597 patent/US9447142B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
IL188518A0 (en) | 2008-04-13 |
EP1902131A1 (de) | 2008-03-26 |
US20150057186A1 (en) | 2015-02-26 |
ATE448305T1 (de) | 2009-11-15 |
WO2007006665A1 (en) | 2007-01-18 |
MX2008000345A (es) | 2008-04-02 |
CN101213299B (zh) | 2013-03-27 |
AU2006268780A1 (en) | 2007-01-18 |
ZA200710687B (en) | 2008-11-26 |
CA2614512A1 (en) | 2007-01-18 |
JP5042218B2 (ja) | 2012-10-03 |
PL1902131T3 (pl) | 2010-05-31 |
KR20080035603A (ko) | 2008-04-23 |
BRPI0613593A2 (pt) | 2011-01-18 |
DK1902131T3 (da) | 2010-03-01 |
HK1122839A1 (en) | 2009-05-29 |
RU2412249C2 (ru) | 2011-02-20 |
US20110118146A1 (en) | 2011-05-19 |
ES2335136T3 (es) | 2010-03-22 |
KR101268939B1 (ko) | 2013-05-30 |
US9447142B2 (en) | 2016-09-20 |
EP1902131B1 (de) | 2009-11-11 |
CA2614512C (en) | 2014-01-07 |
NZ564695A (en) | 2009-02-28 |
RU2008104174A (ru) | 2009-08-20 |
AU2006268780B2 (en) | 2011-03-24 |
US8846577B2 (en) | 2014-09-30 |
JP2009500027A (ja) | 2009-01-08 |
IL188518A (en) | 2011-04-28 |
DE602006010386D1 (en) | 2009-12-24 |
CN101213299A (zh) | 2008-07-02 |
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