NO20080317L - Substituerte tetrahydro-1H-Pyrido[4,3-B]Indoler som serotonin reseptor-agonister og antagonister - Google Patents
Substituerte tetrahydro-1H-Pyrido[4,3-B]Indoler som serotonin reseptor-agonister og antagonisterInfo
- Publication number
- NO20080317L NO20080317L NO20080317A NO20080317A NO20080317L NO 20080317 L NO20080317 L NO 20080317L NO 20080317 A NO20080317 A NO 20080317A NO 20080317 A NO20080317 A NO 20080317A NO 20080317 L NO20080317 L NO 20080317L
- Authority
- NO
- Norway
- Prior art keywords
- formula
- disorder
- indoles
- pyrido
- antagonists
- Prior art date
Links
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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Abstract
Foreliggende søknad beskriver forbindelser, omfattende alle farmasøytisk akseptable salter, promedikamenter, solvater og stereoisomerer derav, i henhold til formel I, farmasøytiske preparater, omfattende minst én forbindelse med formel I og eventuelt minst ett ytterligere terapeutisk middel samt fremgangsmåter for behandling av forskjellige sykdommer, tilstander og lidelser forbundet med modulering av serotoninreseptorer, som for eksempel: metabolske sykdommer, som omfatter, men er ikke begrenset til, fedme, diabetes, diabetiske komplikasjoner, aterosklerose, svekket glukosetoleranse og dyslipidemi; sentralnervesystemsykdommer som omfatter, men er ikke begrenset til, angst, depresjon, obsessiv-kompulsiv lidelse, panikklidelse, psykose, schizofreni, søvnlidelse, seksuell forstyrrelse og sosiofobier; cefalisk smerte; migrene; og mavetarmlidelser, ved anvendelse av forbindelser med formel I
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US70309105P | 2005-07-28 | 2005-07-28 | |
PCT/US2006/029436 WO2007016353A2 (en) | 2005-07-28 | 2006-07-27 | Substituted tetrahydro-1h-pyrido[4,3,b]indoles as serotonin receptor agonists and antagonists |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20080317L true NO20080317L (no) | 2008-02-21 |
Family
ID=37560045
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20080317A NO20080317L (no) | 2005-07-28 | 2008-01-18 | Substituerte tetrahydro-1H-Pyrido[4,3-B]Indoler som serotonin reseptor-agonister og antagonister |
Country Status (14)
Country | Link |
---|---|
US (1) | US20070027178A1 (no) |
EP (1) | EP1910361A2 (no) |
JP (1) | JP2009502959A (no) |
KR (1) | KR20080034171A (no) |
CN (1) | CN101268075A (no) |
AU (1) | AU2006275694A1 (no) |
BR (1) | BRPI0614485A2 (no) |
CA (1) | CA2617102A1 (no) |
EA (1) | EA200800430A1 (no) |
IL (1) | IL188799A0 (no) |
MX (1) | MX2008000811A (no) |
NO (1) | NO20080317L (no) |
WO (1) | WO2007016353A2 (no) |
ZA (1) | ZA200800512B (no) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
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JP2010540439A (ja) * | 2007-09-20 | 2010-12-24 | ディー2イー,エルエルシー | 神経保護性の及び認知を向上させる性質を備えた水素化されたピリド[4,3−b]インドール類のフッ素を含有する誘導体、調製するための工程、並びに使用 |
RU2007139634A (ru) | 2007-10-25 | 2009-04-27 | Сергей Олегович Бачурин (RU) | Новые тиазол-, триазол- или оксадиазол-содержащие тетрациклические соединения |
AU2009204048B2 (en) * | 2008-01-11 | 2013-08-01 | Albany Molecular Research, Inc. | (1-azinone) -substituted pyridoindoles as MCH antagonists |
HK1150388A1 (en) * | 2008-01-25 | 2011-12-23 | Medivation Technologies Inc | New 2,3,4,5-tetrahydro-1h-pyrido[4,3-b]indole compounds and methods of use thereof 2345--1h-[43-b] |
TWI498328B (zh) * | 2008-01-25 | 2015-09-01 | Medivation Technologies Inc | 新穎之2,3,4,5-四氫-1h-吡啶并〔4,3-b〕吲哚化合物及其使用方法 |
RU2544856C2 (ru) * | 2008-01-25 | 2015-03-20 | Сергей Олегович Бачурин | НОВЫЕ ПРОИЗВОДНЫЕ 2,3,4,5-ТЕТРАГИДРО-1-ПИРИДО[4,3-b]ИНДОЛА И СПОСОБЫ ИХ ПРИМЕНЕНИЯ |
EP2340254B8 (en) | 2008-09-15 | 2014-05-21 | Biovista, Inc. | Compositions and methods for treating epilepsy |
JP2012504137A (ja) * | 2008-09-29 | 2012-02-16 | アボット・ラボラトリーズ | インドール誘導体およびインドリン誘導体ならびにそれらの使用方法 |
US9625475B2 (en) * | 2008-09-29 | 2017-04-18 | Abbvie Inc. | Indole and indoline derivatives and methods of use thereof |
WO2010045265A1 (en) * | 2008-10-13 | 2010-04-22 | Biovista, Inc. | Compositions and methods for treating multiple sclerosis |
JP5551708B2 (ja) | 2008-10-31 | 2014-07-16 | メディベイション テクノロジーズ, インコーポレイテッド | アゼピノ[4,5−b]インドール化合物およびその使用方法 |
EP2346332A4 (en) | 2008-10-31 | 2012-08-08 | Medivation Technologies Inc | PYRIDOÝ4,3-BINDOLES CONTAINING RIGID FRAGMENTS |
WO2010068867A1 (en) * | 2008-12-11 | 2010-06-17 | Biovista, Inc. | Methods for treating multiple sclerosis using tetracyclic pyrazinoindoles |
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- 2006-07-27 CA CA002617102A patent/CA2617102A1/en not_active Abandoned
- 2006-07-27 US US11/494,156 patent/US20070027178A1/en not_active Abandoned
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IL188799A0 (en) | 2008-08-07 |
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US20070027178A1 (en) | 2007-02-01 |
EA200800430A1 (ru) | 2008-06-30 |
MX2008000811A (es) | 2008-03-18 |
JP2009502959A (ja) | 2009-01-29 |
WO2007016353A2 (en) | 2007-02-08 |
KR20080034171A (ko) | 2008-04-18 |
ZA200800512B (en) | 2009-06-24 |
CN101268075A (zh) | 2008-09-17 |
EP1910361A2 (en) | 2008-04-16 |
BRPI0614485A2 (pt) | 2011-03-29 |
AU2006275694A1 (en) | 2007-02-08 |
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