NO20075766L - Aminoalkyl-amidometyl-substituerte 2-(4-sulfonylamino)-3-hydroksy-3,4-dihydro-2H-kromen-6-yl-derivater og deres anvendelse som kaliumkanalblokkere - Google Patents

Aminoalkyl-amidometyl-substituerte 2-(4-sulfonylamino)-3-hydroksy-3,4-dihydro-2H-kromen-6-yl-derivater og deres anvendelse som kaliumkanalblokkere

Info

Publication number
NO20075766L
NO20075766L NO20075766A NO20075766A NO20075766L NO 20075766 L NO20075766 L NO 20075766L NO 20075766 A NO20075766 A NO 20075766A NO 20075766 A NO20075766 A NO 20075766A NO 20075766 L NO20075766 L NO 20075766L
Authority
NO
Norway
Prior art keywords
sup
amidomethyl
chromene
sulfonylamino
aminoalkyl
Prior art date
Application number
NO20075766A
Other languages
English (en)
Norwegian (no)
Inventor
Dieter Ziegler
Michael Weske
Yvan Fischer
Brian Moloney
Lester Marrison
Michael Mlinaric
Christiane Boecker
Reinhard Brueckner
Klaus Witte
Original Assignee
Solvay Pharm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Solvay Pharm Gmbh filed Critical Solvay Pharm Gmbh
Publication of NO20075766L publication Critical patent/NO20075766L/no

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/68—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with nitrogen atoms directly attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
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    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
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  • Cardiology (AREA)
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  • Ophthalmology & Optometry (AREA)
  • Urology & Nephrology (AREA)
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  • Reproductive Health (AREA)
  • Rheumatology (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
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  • Nutrition Science (AREA)
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  • Gastroenterology & Hepatology (AREA)
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NO20075766A 2005-04-12 2007-11-09 Aminoalkyl-amidometyl-substituerte 2-(4-sulfonylamino)-3-hydroksy-3,4-dihydro-2H-kromen-6-yl-derivater og deres anvendelse som kaliumkanalblokkere NO20075766L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05102868 2005-04-12
PCT/EP2006/061511 WO2006108837A1 (en) 2005-04-12 2006-04-11 Aminoalkyl-amidomethyl-substituted 2- (4-sulphonylamino) -3-hydroxy-3 , 4-dihydro-2h-cromen-6-yl derivatives and their use as potassium channel blockers

Publications (1)

Publication Number Publication Date
NO20075766L true NO20075766L (no) 2007-11-09

Family

ID=34939239

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20075766A NO20075766L (no) 2005-04-12 2007-11-09 Aminoalkyl-amidometyl-substituerte 2-(4-sulfonylamino)-3-hydroksy-3,4-dihydro-2H-kromen-6-yl-derivater og deres anvendelse som kaliumkanalblokkere

Country Status (17)

Country Link
EP (1) EP1871758B1 (de)
JP (1) JP4971304B2 (de)
KR (1) KR20070121024A (de)
CN (1) CN101160301B (de)
AT (1) ATE478855T1 (de)
AU (1) AU2006234295B2 (de)
BR (1) BRPI0610559A2 (de)
CA (1) CA2604356A1 (de)
DE (1) DE602006016420D1 (de)
HK (1) HK1116167A1 (de)
IL (1) IL186513A (de)
MX (1) MX2007011198A (de)
NO (1) NO20075766L (de)
RU (1) RU2413725C2 (de)
UA (1) UA96734C2 (de)
WO (1) WO2006108837A1 (de)
ZA (1) ZA200707473B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO3175985T3 (de) 2011-07-01 2018-04-28
CA2862670A1 (en) 2012-01-27 2013-08-01 Gilead Sciences, Inc. Combination therapies using late sodium ion channel blockers and potassium ion channel blockers
CN103012380B (zh) * 2013-01-10 2015-03-04 山东大学 一种色满类化合物及其制备方法与应用
WO2014134419A1 (en) 2013-03-01 2014-09-04 Gilead Sciences, Inc. Use of ikach blockers for the treatment of cardiac diseases
AU2015315177A1 (en) * 2014-09-10 2017-03-16 Epizyme, Inc. Substituted pyrrolidine carboxamide compounds

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19742508A1 (de) * 1997-09-26 1999-04-01 Hoechst Marion Roussel De Gmbh Sulfonamid-substituierte Chromane, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltende pharmazeutische Zubereitungen
DE19748469A1 (de) * 1997-11-03 1999-05-06 Hoechst Marion Roussel De Gmbh Sulfonamid-substituierte Benzopyranderivate, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament sowie sie enthaltende pharmazeutische Zubereitungen
JP2002523451A (ja) * 1998-09-01 2002-07-30 ブリストル−マイヤーズ スクイブ カンパニー カリウムチャネル抑制剤および方法
IL141341A0 (en) * 1998-09-04 2002-03-10 Procter & Gamble Substituted dihydrobenzopyrans useful as antiarrhythmic agents
WO2000058300A1 (fr) * 1999-03-25 2000-10-05 Nissan Chemical Industries, Ltd. Derives du chroman
DE10348298A1 (de) * 2003-10-17 2005-05-19 Solvay Pharmaceuticals Gmbh Amidomethyl-substituierte 2-(4-Sulfonylamino)-3-hydroxy-3,4-dihydro-2H-chromen-6-ylderivade, Verfahren und Zwischenprodukte zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel

Also Published As

Publication number Publication date
KR20070121024A (ko) 2007-12-26
UA96734C2 (en) 2011-12-12
IL186513A0 (en) 2008-01-20
WO2006108837A1 (en) 2006-10-19
CN101160301B (zh) 2012-03-28
JP4971304B2 (ja) 2012-07-11
BRPI0610559A2 (pt) 2010-06-29
ATE478855T1 (de) 2010-09-15
AU2006234295B2 (en) 2011-10-13
AU2006234295A1 (en) 2006-10-19
IL186513A (en) 2013-03-24
DE602006016420D1 (de) 2010-10-07
ZA200707473B (en) 2008-12-31
RU2413725C2 (ru) 2011-03-10
CN101160301A (zh) 2008-04-09
EP1871758A1 (de) 2008-01-02
EP1871758B1 (de) 2010-08-25
CA2604356A1 (en) 2006-10-19
HK1116167A1 (en) 2008-12-19
JP2008536842A (ja) 2008-09-11
MX2007011198A (es) 2007-10-17
RU2007141564A (ru) 2009-05-20

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