NO20075541L - Mono-lysine salter av azolforbindelser - Google Patents

Mono-lysine salter av azolforbindelser

Info

Publication number
NO20075541L
NO20075541L NO20075541A NO20075541A NO20075541L NO 20075541 L NO20075541 L NO 20075541L NO 20075541 A NO20075541 A NO 20075541A NO 20075541 A NO20075541 A NO 20075541A NO 20075541 L NO20075541 L NO 20075541L
Authority
NO
Norway
Prior art keywords
mono
compounds
fungal
formula
triazole
Prior art date
Application number
NO20075541A
Other languages
English (en)
Norwegian (no)
Inventor
Chung-Pin Chen
Michael G Fakes
Yadagiri Pendri
Qi Gao
Susanne Kiau
Blisse Vakkalagadda
Original Assignee
Eisai R&D Man Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai R&D Man Co Ltd filed Critical Eisai R&D Man Co Ltd
Publication of NO20075541L publication Critical patent/NO20075541L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/26Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one amino group bound to the carbon skeleton, e.g. lysine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/08Esters of oxyacids of phosphorus
    • C07F9/09Esters of phosphoric acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65586Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system at least one of the hetero rings does not contain nitrogen as ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO20075541A 2005-05-03 2007-11-02 Mono-lysine salter av azolforbindelser NO20075541L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US67693205P 2005-05-03 2005-05-03
PCT/JP2006/309435 WO2006118351A1 (en) 2005-05-03 2006-05-01 Mono-lysine salts of azole compounds

Publications (1)

Publication Number Publication Date
NO20075541L true NO20075541L (no) 2007-11-28

Family

ID=36910951

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20075541A NO20075541L (no) 2005-05-03 2007-11-02 Mono-lysine salter av azolforbindelser

Country Status (34)

Country Link
US (1) US20060264406A1 (el)
EP (1) EP1877403B1 (el)
JP (1) JP4015691B1 (el)
KR (1) KR100887044B1 (el)
CN (1) CN101213193B (el)
AR (1) AR053862A1 (el)
AT (1) ATE503753T1 (el)
AU (1) AU2006241694B2 (el)
BR (1) BRPI0610423B8 (el)
CA (1) CA2606185C (el)
CY (1) CY1111569T1 (el)
DE (1) DE602006020998D1 (el)
DK (1) DK1877403T3 (el)
EC (1) ECSP077812A (el)
ES (1) ES2361768T3 (el)
HK (1) HK1117502A1 (el)
HR (1) HRP20110467T1 (el)
IL (1) IL187059A (el)
JO (1) JO2691B1 (el)
MX (1) MX2007013605A (el)
MY (1) MY138095A (el)
NO (1) NO20075541L (el)
NZ (1) NZ563092A (el)
PE (1) PE20071423A1 (el)
PL (1) PL1877403T3 (el)
PT (1) PT1877403E (el)
RS (1) RS51779B (el)
RU (1) RU2399625C2 (el)
SA (1) SA06270126B1 (el)
SI (1) SI1877403T1 (el)
TW (1) TWI363630B (el)
UY (1) UY29507A1 (el)
WO (1) WO2006118351A1 (el)
ZA (1) ZA200709127B (el)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2432360T3 (es) * 2005-12-20 2013-12-03 Eisai R&D Management Co., Ltd. Procedimiento para la producción de profármaco de azol soluble en agua
CN101389333A (zh) 2006-02-22 2009-03-18 卫材R&D管理有限公司 稳定化药物组合物
CN105287403A (zh) * 2014-08-02 2016-02-03 陕西合成药业股份有限公司 一种泊沙康唑前体药物的冻干组合物及其制备方法和用途
CN106432338A (zh) * 2015-08-08 2017-02-22 陕西合成药业股份有限公司 泊沙康唑衍生物、合成和在长效制剂中的用途
WO2019106571A1 (en) 2017-11-28 2019-06-06 Roivant Sciences Gmbh Dosing regimens for the treatment of fungal infections
CN110938093B (zh) * 2018-09-21 2022-08-19 华创合成制药股份有限公司 一种泊沙康唑磷酸酯单胆碱盐及其制备方法和用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE186540T1 (de) * 1994-01-24 1999-11-15 Janssen Pharmaceutica Nv Wasserlösliche azol-antifungus
NZ270418A (en) * 1994-02-07 1997-09-22 Eisai Co Ltd Polycyclic triazole & imidazole derivatives, antifungal compositions
US5883097A (en) * 1998-04-16 1999-03-16 Schering Corporation Soluble azole antifungal salt
US6265584B1 (en) * 1998-05-22 2001-07-24 Bristol-Myers Squibb Company Water soluble prodrugs of azole compounds
WO2000030655A1 (en) * 1998-11-20 2000-06-02 Bristol-Myers Squibb Company Water soluble prodrugs of azole compounds
US6235728B1 (en) * 1999-02-19 2001-05-22 Bristol-Myers Squibb Company Water-soluble prodrugs of azole compounds
US6362172B2 (en) * 2000-01-20 2002-03-26 Bristol-Myers Squibb Company Water soluble prodrugs of azole compounds
US6448401B1 (en) * 2000-11-20 2002-09-10 Bristol-Myers Squibb Company Process for water soluble azole compounds

Also Published As

Publication number Publication date
PT1877403E (pt) 2011-05-31
TWI363630B (en) 2012-05-11
EP1877403B1 (en) 2011-03-30
CA2606185A1 (en) 2006-11-09
MX2007013605A (es) 2008-01-24
DK1877403T3 (da) 2011-05-09
MY138095A (en) 2009-04-30
JP4015691B1 (ja) 2007-11-28
CN101213193B (zh) 2011-02-02
JP2008544948A (ja) 2008-12-11
NZ563092A (en) 2010-06-25
DE602006020998D1 (de) 2011-05-12
EP1877403A1 (en) 2008-01-16
ECSP077812A (es) 2008-01-23
CN101213193A (zh) 2008-07-02
IL187059A (en) 2012-08-30
BRPI0610423A2 (pt) 2010-06-22
RS51779B (en) 2011-12-31
CA2606185C (en) 2012-08-28
TW200722093A (en) 2007-06-16
ES2361768T3 (es) 2011-06-22
RU2007140788A (ru) 2009-06-10
AR053862A1 (es) 2007-05-23
ATE503753T1 (de) 2011-04-15
HK1117502A1 (en) 2009-01-16
KR20070088460A (ko) 2007-08-29
BRPI0610423B1 (pt) 2020-11-10
CY1111569T1 (el) 2015-10-07
US20060264406A1 (en) 2006-11-23
ZA200709127B (en) 2008-07-30
SA06270126B1 (ar) 2009-09-02
PL1877403T3 (pl) 2011-08-31
IL187059A0 (en) 2008-02-09
WO2006118351A1 (en) 2006-11-09
JO2691B1 (en) 2013-03-03
BRPI0610423B8 (pt) 2021-05-25
SI1877403T1 (sl) 2011-05-31
UY29507A1 (es) 2006-11-30
HRP20110467T1 (hr) 2011-07-31
AU2006241694B2 (en) 2011-10-20
RU2399625C2 (ru) 2010-09-20
AU2006241694A1 (en) 2006-11-09
KR100887044B1 (ko) 2009-03-04
PE20071423A1 (es) 2006-12-17

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