NO20074722L - Anvendelse av en epidermal vekstfaktor reseptor kinase inhibitor (EGRR) i gefitinib resistente pasienter - Google Patents
Anvendelse av en epidermal vekstfaktor reseptor kinase inhibitor (EGRR) i gefitinib resistente pasienterInfo
- Publication number
- NO20074722L NO20074722L NO20074722A NO20074722A NO20074722L NO 20074722 L NO20074722 L NO 20074722L NO 20074722 A NO20074722 A NO 20074722A NO 20074722 A NO20074722 A NO 20074722A NO 20074722 L NO20074722 L NO 20074722L
- Authority
- NO
- Norway
- Prior art keywords
- kinase inhibitor
- egrr
- growth factor
- factor receptor
- epidermal growth
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4706—4-Aminoquinolines; 8-Aminoquinolines, e.g. chloroquine, primaquine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Abstract
Foreliggende oppfinnelse beskriver en metode for behandling eller hemming av kreft hos et menneske som har minst én av en Exon 19 del E746-A750 og/eller en Exon 21 punktmutasjon omfattende administrering til nevnte menneske gefitinib og/eller iressa alene eller i kombinasjon med andre cytotoksiske midler eller kjemoterapeutiske midler og en effektiv mengde av EGFR kinase inhibitor.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US67128705P | 2005-04-14 | 2005-04-14 | |
PCT/US2006/012877 WO2006113151A2 (en) | 2005-04-14 | 2006-04-07 | Use of an epidermal growth factor receptor kinase inhibitor (egfr) in gefitinib resistant patients |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20074722L true NO20074722L (no) | 2007-11-12 |
Family
ID=36791648
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20074722A NO20074722L (no) | 2005-04-14 | 2007-09-17 | Anvendelse av en epidermal vekstfaktor reseptor kinase inhibitor (EGRR) i gefitinib resistente pasienter |
Country Status (19)
Country | Link |
---|---|
US (1) | US20060235046A1 (no) |
EP (1) | EP1871371A2 (no) |
JP (1) | JP2008536847A (no) |
KR (1) | KR20080002826A (no) |
CN (1) | CN101160129A (no) |
AR (1) | AR053357A1 (no) |
AU (1) | AU2006236940A1 (no) |
BR (1) | BRPI0610574A2 (no) |
CA (1) | CA2646257A1 (no) |
CR (1) | CR9415A (no) |
GT (1) | GT200600146A (no) |
IL (1) | IL186302A0 (no) |
MX (1) | MX2007012662A (no) |
NO (1) | NO20074722L (no) |
PE (1) | PE20061396A1 (no) |
RU (1) | RU2007134908A (no) |
TW (1) | TW200718421A (no) |
WO (1) | WO2006113151A2 (no) |
ZA (1) | ZA200708755B (no) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102886045A (zh) | 2005-02-03 | 2013-01-23 | 综合医院公司 | 治疗吉非替尼耐药性癌症的方法 |
KR101354828B1 (ko) | 2005-11-04 | 2014-02-18 | 와이어쓰 엘엘씨 | mTOR 저해자, 헤르셉틴, 및/또는 HKI-272의항신생물성 조합 |
US8022216B2 (en) | 2007-10-17 | 2011-09-20 | Wyeth Llc | Maleate salts of (E)-N-{4-[3-chloro-4-(2-pyridinylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolinyl}-4-(dimethylamino)-2-butenamide and crystalline forms thereof |
EP3135285B1 (en) | 2008-06-17 | 2018-08-15 | Wyeth LLC | Antineoplastic combinations containing hki-272 and vinorelbine |
EP2326329B1 (en) * | 2008-08-04 | 2017-01-11 | Wyeth LLC | Antineoplastic combinations of 4-anilino-3-cyanoquinolines and capecitabine |
BRPI0918970A2 (pt) * | 2008-09-05 | 2019-09-24 | Avila Therapeutics Inc | algoritmo para projeto de inibidores irreversíveis |
WO2010086382A1 (en) * | 2009-01-30 | 2010-08-05 | Pronota N.V. | Target for treatment of acute heart failure |
DK3000467T3 (da) | 2009-04-06 | 2023-03-27 | Wyeth Llc | Behandling med neratinib mod brystkræft |
SG179172A1 (en) | 2009-09-16 | 2012-04-27 | Avila Therapeutics Inc | Protein kinase conjugates and inhibitors |
MX2012007684A (es) | 2009-12-30 | 2012-10-05 | Avila Therapeutics Inc | Modificacion covalente ligando dirigida de proteina. |
JP6769963B2 (ja) | 2014-08-29 | 2020-10-14 | ティエエッセ ファルマ ソチエタ レスポンサビリタ リミタータ | α−アミノ−β−カルボキシムコン酸セミアルデヒド脱炭酸酵素の阻害剤 |
US9364469B1 (en) * | 2015-08-26 | 2016-06-14 | Macau University Of Science And Technology | Identification of a new AMPK activator for treatment of lung cancer |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0218526D0 (en) * | 2002-08-09 | 2002-09-18 | Astrazeneca Ab | Combination therapy |
CN1832757A (zh) * | 2003-08-01 | 2006-09-13 | 惠氏控股公司 | 表皮生长因子受体激酶抑制剂与细胞毒性剂组合在治疗和抑制癌症中的用途 |
US7399865B2 (en) * | 2003-09-15 | 2008-07-15 | Wyeth | Protein tyrosine kinase enzyme inhibitors |
CN104480200B (zh) * | 2004-03-31 | 2017-12-29 | 综合医院公司 | 测定癌症对表皮生长因子受体靶向性治疗反应性的方法 |
CN102886045A (zh) * | 2005-02-03 | 2013-01-23 | 综合医院公司 | 治疗吉非替尼耐药性癌症的方法 |
-
2006
- 2006-04-07 JP JP2008506526A patent/JP2008536847A/ja not_active Withdrawn
- 2006-04-07 MX MX2007012662A patent/MX2007012662A/es unknown
- 2006-04-07 KR KR1020077023472A patent/KR20080002826A/ko not_active Application Discontinuation
- 2006-04-07 WO PCT/US2006/012877 patent/WO2006113151A2/en active Application Filing
- 2006-04-07 CN CNA2006800123594A patent/CN101160129A/zh active Pending
- 2006-04-07 EP EP06740650A patent/EP1871371A2/en not_active Withdrawn
- 2006-04-07 BR BRPI0610574-2A patent/BRPI0610574A2/pt not_active IP Right Cessation
- 2006-04-07 RU RU2007134908/14A patent/RU2007134908A/ru not_active Application Discontinuation
- 2006-04-07 CA CA002646257A patent/CA2646257A1/en not_active Abandoned
- 2006-04-07 AU AU2006236940A patent/AU2006236940A1/en not_active Abandoned
- 2006-04-10 TW TW095112747A patent/TW200718421A/zh unknown
- 2006-04-10 GT GT200600146A patent/GT200600146A/es unknown
- 2006-04-12 AR ARP060101468A patent/AR053357A1/es unknown
- 2006-04-12 US US11/403,170 patent/US20060235046A1/en not_active Abandoned
- 2006-04-17 PE PE2006000400A patent/PE20061396A1/es not_active Application Discontinuation
-
2007
- 2007-09-17 NO NO20074722A patent/NO20074722L/no not_active Application Discontinuation
- 2007-09-25 IL IL186302A patent/IL186302A0/en unknown
- 2007-10-04 CR CR9415A patent/CR9415A/es not_active Application Discontinuation
- 2007-10-12 ZA ZA200708755A patent/ZA200708755B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
CR9415A (es) | 2008-01-21 |
JP2008536847A (ja) | 2008-09-11 |
GT200600146A (es) | 2006-11-07 |
CA2646257A1 (en) | 2006-10-26 |
MX2007012662A (es) | 2008-04-04 |
KR20080002826A (ko) | 2008-01-04 |
WO2006113151A3 (en) | 2007-01-11 |
PE20061396A1 (es) | 2007-01-12 |
TW200718421A (en) | 2007-05-16 |
BRPI0610574A2 (pt) | 2010-07-06 |
CN101160129A (zh) | 2008-04-09 |
WO2006113151A2 (en) | 2006-10-26 |
US20060235046A1 (en) | 2006-10-19 |
IL186302A0 (en) | 2008-08-07 |
AR053357A1 (es) | 2007-05-02 |
EP1871371A2 (en) | 2008-01-02 |
ZA200708755B (en) | 2008-10-29 |
AU2006236940A1 (en) | 2006-10-26 |
RU2007134908A (ru) | 2009-05-20 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO20074722L (no) | Anvendelse av en epidermal vekstfaktor reseptor kinase inhibitor (EGRR) i gefitinib resistente pasienter | |
NO20060398L (no) | Anvendelse av en kombinasjon av en epidermal vekstfaktor reseptor kinase inhibitor og cytotoksiske midler for behandling og hemming av kreft | |
MX2021005011A (es) | Métodos de tratamiento del cáncer en pacientes identificados por biomarcadores con inhibidores no covalentes de cinasa 7 dependiente de ciclina (cdk7). | |
ECSP099414A (es) | Derivados de dihidropiridina de utilidad como inhibidores de la proteína quinasa | |
LU93160I2 (en) | Methode de traitement du cancer resistant au gefitinib | |
TNSN08088A1 (en) | Substituted benzimidazoles as kinase inhibitors | |
MX2012002480A (es) | Inhibidores de jak2 y su uso en el tratamiento de enfermedades mieloproliferativas y cancer. | |
NO20090025L (no) | Pyrrolotriazinkinaseinhibitorer | |
HK1166465A1 (en) | 1h-benzimidazole-4-carboxamides substituted with a quaternary carbon at the 2-position as parp inhibitors for use in treating cancer | |
MX2009009304A (es) | Inhibidores de cinasa pim y metodos para su uso. | |
IS2855B (is) | 4-anilínókínasólínafleiður sem andfjölgunarefni | |
ECSP067080A (es) | DIFENILIMIDAZOPIRIMIDINA Y AMINAS IMIDAZOL COMO INHIBIDORES DE ß-SECRETASA | |
GEP20115283B (en) | Pyrrolopyrimidine compounds and their uses | |
TW200736229A (en) | Substituted 1H-benzimidazole-4-carboxamides are potent PARP inhibitors | |
NO20080168L (no) | Aminoquinolin- og aminoquinoazolinkinasemodulatorer | |
TW200800989A (en) | Pyrrolopyridine kinase inhibiting compounds | |
BRPI0815715A8 (pt) | Compostos 5-(-4-(haloalcóxi)fenil)pirimidina-2-amina e composições como inibidores de quinases. | |
NO20061415L (no) | Kinazolinderivater | |
NO20082894L (no) | Metode for behandling av kognitiv dysfunksjon | |
DE602005023732D1 (de) | Pyrrolotriazinverbindungen | |
WO2007016338A3 (en) | Use of chk2 kinase inhibitors for cancer treatment | |
DE602006017574D1 (de) | Als protein-kinase-inhibitoren nutzbare benzimidazole | |
NO20092035L (no) | Tiazolylforbindelser anvendbare som kinaseinhibitorer | |
BRPI0511475A (pt) | combinação, composição farmacêutica, uso de uma combinação, e, método para o tratamento de cáncer | |
MXPA05011858A (es) | Agentes terapeuticos que comprenden un agente antiagiongenico en combinacion con un inhibidor src y su uso terapeutico. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |