NO20074162L - Makrolider med anti-inflammatorisk aktivitet - Google Patents

Makrolider med anti-inflammatorisk aktivitet

Info

Publication number
NO20074162L
NO20074162L NO20074162A NO20074162A NO20074162L NO 20074162 L NO20074162 L NO 20074162L NO 20074162 A NO20074162 A NO 20074162A NO 20074162 A NO20074162 A NO 20074162A NO 20074162 L NO20074162 L NO 20074162L
Authority
NO
Norway
Prior art keywords
macrolides
excessive
inflammatory activity
activity
relates
Prior art date
Application number
NO20074162A
Other languages
English (en)
Norwegian (no)
Inventor
Boska Hrvacic
Sulejman Alihodzic
Ognjen Culic
Martina Bosnar
Nikola Marjanovic
Dubravko Jelic
Vanja Vela
Zorica Marusic-Istuk
Vesna Erakovic
Berislav Bosnjak
Marija Tomaskovic
Vesna Munic
Vanesa Ivetic
Antun Hutinec
Goran Kragol
Marija Leljak
Original Assignee
Glaxosmithkline Zagreb
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Zagreb filed Critical Glaxosmithkline Zagreb
Publication of NO20074162L publication Critical patent/NO20074162L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Otolaryngology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO20074162A 2005-01-13 2007-08-13 Makrolider med anti-inflammatorisk aktivitet NO20074162L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US64384105P 2005-01-13 2005-01-13
US71582805P 2005-09-09 2005-09-09
PCT/IB2006/001238 WO2006087644A2 (en) 2005-01-13 2006-01-13 Macrolides with anti-inflammatory activity

Publications (1)

Publication Number Publication Date
NO20074162L true NO20074162L (no) 2007-09-18

Family

ID=36916830

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20074162A NO20074162L (no) 2005-01-13 2007-08-13 Makrolider med anti-inflammatorisk aktivitet

Country Status (18)

Country Link
US (2) US8080529B2 (OSRAM)
EP (1) EP1851236B1 (OSRAM)
JP (1) JP5036558B2 (OSRAM)
KR (1) KR20070105993A (OSRAM)
CN (1) CN101142225B (OSRAM)
AT (1) ATE476438T1 (OSRAM)
AU (1) AU2006215315B2 (OSRAM)
CA (1) CA2594820A1 (OSRAM)
CY (1) CY1110866T1 (OSRAM)
DE (1) DE602006015919D1 (OSRAM)
DK (1) DK1851236T3 (OSRAM)
HR (1) HRP20100549T1 (OSRAM)
IL (1) IL184438A (OSRAM)
NO (1) NO20074162L (OSRAM)
PL (1) PL1851236T3 (OSRAM)
PT (1) PT1851236E (OSRAM)
RS (1) RS51479B (OSRAM)
WO (1) WO2006087644A2 (OSRAM)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009130189A1 (en) * 2008-04-23 2009-10-29 Glaxosmithkline Istrazivacki Centar Zagreb D.O.O. 2'-o,3'-n-bridged macrolides
CN101423539B (zh) * 2008-12-09 2011-04-27 山东大学 4″,11-二氨基甲酸酯阿奇霉素衍生物、制备方法及其药物组合物
CN102378763A (zh) 2009-01-30 2012-03-14 葛兰素集团有限公司 消炎的大环内酯
ES2582794T3 (es) 2009-08-13 2016-09-15 Basilea Pharmaceutica Ag Nuevos macrólidos y su uso
WO2011131749A1 (en) 2010-04-23 2011-10-27 Glaxo Group Limited New 14 and 15 membered macrolides for the treatment of neutrophil dominated inflammatory diseases
JP6437523B2 (ja) 2013-04-04 2018-12-12 プレジデント アンド フェローズ オブ ハーバード カレッジ マクロライドならびにそれらの調製および使用の方法
CA2908620A1 (en) 2013-04-10 2014-10-16 Probiotic Pharmaceuticals Aps Azithromycin antimicrobial derivatives with non-antibiotic pharmaceutical effect
US10633407B2 (en) 2014-10-08 2020-04-28 President And Fellows Of Harvard College 14-membered ketolides and methods of their preparation and use
EP3273969A4 (en) 2015-03-25 2018-11-21 President and Fellows of Harvard College Macrolides with modified desosamine sugars and uses thereof
GB201520419D0 (en) 2015-11-19 2016-01-06 Epi Endo Pharmaceuticals Ehf Compounds
EP4118092B1 (en) * 2020-03-12 2025-07-16 Zoetis Services LLC Immunomodulating o-het-aryl azalides
WO2022128054A1 (en) 2020-12-14 2022-06-23 Symrise Ag Medicament for fighting inflammatory conditions of human skin (iv)
CN114858953B (zh) * 2022-05-20 2023-11-21 大连工业大学 一种动物源食品中红霉素及降解产物的检测试剂盒及检测方法
GB202404587D0 (en) 2024-03-28 2024-05-15 Epiendo Pharmaceuticals Ehf Chemical forms

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0126344A2 (en) * 1983-05-20 1984-11-28 Abbott Laboratories Tripeptide esters of therapeutic agents
SI9011409A (en) * 1990-07-18 1995-10-31 Pliva Pharm & Chem Works O-methyl azitromycin derivates, methods and intermediates for their preparation and methods for preparation of pharmaceuticals products which comprise them
EP0895999A1 (en) * 1997-08-06 1999-02-10 Pfizer Products Inc. C-4" substituted macrolide antibiotics
HRP980189B1 (en) 1998-04-06 2004-04-30 Pliva Pharm & Chem Works Novel 15-membered lactams ketolides
AU2003255851B2 (en) * 2002-07-08 2009-07-23 Glaxosmithkline Istrazivacki Centar Zagreb D.O.O. New compounds, compositions and methods for treatment of inflammatory diseases and conditions
GB0310986D0 (en) * 2003-05-13 2003-06-18 Glaxo Group Ltd Novel compounds
WO2006077501A2 (en) 2005-01-13 2006-07-27 Glaxosmithkline Istrazivacki Centar Zagreb D.O.O. Decladinosyl-macrolides with anti-inflammatory activity
JP5065910B2 (ja) 2005-01-14 2012-11-07 グラクソ グループ リミテッド ビオチンおよび光親和性基を含む、マクロライド標的同定用のマクロライド化合物
CN102378763A (zh) 2009-01-30 2012-03-14 葛兰素集团有限公司 消炎的大环内酯

Also Published As

Publication number Publication date
US8080529B2 (en) 2011-12-20
HK1112920A1 (en) 2008-09-19
KR20070105993A (ko) 2007-10-31
AU2006215315A1 (en) 2006-08-24
CN101142225B (zh) 2011-09-07
CA2594820A1 (en) 2006-08-24
IL184438A (en) 2011-12-29
CY1110866T1 (el) 2015-06-10
US20080221046A1 (en) 2008-09-11
JP2008526950A (ja) 2008-07-24
EP1851236A2 (en) 2007-11-07
EP1851236B1 (en) 2010-08-04
DK1851236T3 (da) 2010-11-22
AU2006215315B2 (en) 2012-02-16
PL1851236T3 (pl) 2011-05-31
ATE476438T1 (de) 2010-08-15
CN101142225A (zh) 2008-03-12
WO2006087644A3 (en) 2007-03-15
HRP20100549T1 (hr) 2010-11-30
JP5036558B2 (ja) 2012-09-26
DE602006015919D1 (de) 2010-09-16
WO2006087644A2 (en) 2006-08-24
IL184438A0 (en) 2008-12-29
PT1851236E (pt) 2010-10-25
RS51479B (sr) 2011-04-30
US20120058963A1 (en) 2012-03-08

Similar Documents

Publication Publication Date Title
IL184438A0 (en) Macrolides with anti-inflammatory activity
DOP2009000141A (es) Derivados de dihidropiridina de utilidad como inhibidores de la proteína quinasa
ATE416177T1 (de) Hetaryloxy-substituierte phenylaminopyrimidine als rho-kinasehemmer
NO20073719L (no) Kjemiske forbindelser
EA200870019A1 (ru) Лактамовые соединения и способы их применения
NO20074634L (no) Substituerte heterocykler og deres anvendelse som CHK1-, PDK1- og PAK-inhibitorer
DK2024367T3 (da) Tetrahydropyrrolopyrimidindioner og deres anvendelse som inhibitorer af human neutrofil elastase
EA200870216A1 (ru) Амидо соединения и их применение в качестве лекарственных средств
NO20080487L (no) Rekominant interferona2 (IFNa2) mutanter
NO20084024L (no) Imidazolbaserte forbindelser, preparater omfattende slike, og anvendelse av slike
PA8784001A1 (es) Oxazolidinonas sustituidas y su uso
BR122020006906B8 (pt) compostos e composições farmacêuticas antivirais
NO20082026L (no) Deazapuriner som er nyttige som inhibitorer for Janus-kinaser
BRPI0511111A (pt) compostos de pirrol como inibidores de cinase de proteìna de erk, sua sìntese e seus intermediários
BRPI0507462A (pt) compostos de quinolina substituìdos
MX2010001849A (es) Depsipeptidos ciclicos.
ECSP077235A (es) Benzamidas sustituidas por trifluoro-metilo como inhibidores de quinasa
UY29264A1 (es) Tiazolidinonas metasustituidas, su preparación y su uso como medicamento
DOP2006000024A (es) Tiazolidinonas, su preparación y su uso como medicamento
DE602006004555D1 (de) Decladinosyl-macrolide mit entzündungshemmender wirkung
WO2007041614A3 (en) Long acting vegf inhibitors and methods of use
ECSP12011748A (es) Derivados de 3,5-diciano-4-(1h-indazol-5-il)-2,6-dimetil-1,4-dihidropiridina fluoro-sustituidos y procedimientos de uso de los mismos
WO2006108679A3 (en) Substances and pharmaceutical compositions for the inhibition of glyoxalases and their use to combat cancer
DE602006006030D1 (de) Neue makrolide
EP1841420A4 (en) TREATMENT OF REMEDIENT-RESISTANT PROLIFERATIVE DISEASES

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application