UY29264A1 - Tiazolidinonas metasustituidas, su preparación y su uso como medicamento - Google Patents

Tiazolidinonas metasustituidas, su preparación y su uso como medicamento

Info

Publication number
UY29264A1
UY29264A1 UY29264A UY29264A UY29264A1 UY 29264 A1 UY29264 A1 UY 29264A1 UY 29264 A UY29264 A UY 29264A UY 29264 A UY29264 A UY 29264A UY 29264 A1 UY29264 A1 UY 29264A1
Authority
UY
Uruguay
Prior art keywords
thiazolidinones
preparation
metas
replaced
medicinal product
Prior art date
Application number
UY29264A
Other languages
English (en)
Inventor
Olaf Prien
Holger Hess-Stumpp
Dirk Kosemund
Gerhard Siemeister
Volker Schulze
Knut Eis
Lars Wortmann
Uwe Eberspaecher
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35895206&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UY29264(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DE102004061503A external-priority patent/DE102004061503A1/de
Application filed by Schering Ag filed Critical Schering Ag
Publication of UY29264A1 publication Critical patent/UY29264A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/14—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)

Abstract

La invención se relaciona con tiazolidinonas de la fórmula general I Y a su preparación y utilización como inhibidores de la polo-quinasa (PLK) para el tratamiento de varias enfermedades.
UY29264A 2004-12-15 2005-12-20 Tiazolidinonas metasustituidas, su preparación y su uso como medicamento UY29264A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102004061503A DE102004061503A1 (de) 2004-12-15 2004-12-15 Metasubstituierte Thiazolidinone, deren Herstellung und Verwendung als Arzneimittel
US63777704P 2004-12-22 2004-12-22

Publications (1)

Publication Number Publication Date
UY29264A1 true UY29264A1 (es) 2006-06-30

Family

ID=35895206

Family Applications (1)

Application Number Title Priority Date Filing Date
UY29264A UY29264A1 (es) 2004-12-15 2005-12-20 Tiazolidinonas metasustituidas, su preparación y su uso como medicamento

Country Status (18)

Country Link
US (2) US20070015759A1 (es)
EP (1) EP1824834A1 (es)
JP (1) JP2008524139A (es)
KR (1) KR20070092740A (es)
AR (1) AR055698A1 (es)
AU (1) AU2005315835A1 (es)
BR (1) BRPI0519040A2 (es)
CA (1) CA2590396A1 (es)
CR (1) CR9183A (es)
GT (1) GT200500366A (es)
IL (1) IL183395A0 (es)
MX (1) MX2007007245A (es)
NO (1) NO20073631L (es)
PA (1) PA8656501A1 (es)
PE (1) PE20061157A1 (es)
TW (1) TW200628458A (es)
UY (1) UY29264A1 (es)
WO (1) WO2006063806A1 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005005395A1 (de) * 2005-02-03 2006-08-10 Schering Aktiengesellschaft Thiazolidinone, deren Herstellung und Verwendung als Arzneimittel
EP1989330A4 (en) * 2006-01-31 2009-10-21 Elan Pharm Inc ALPHA-SYNUCLEINE KINASE
WO2009103010A2 (en) * 2008-02-13 2009-08-20 Elan Pharmaceuticals, Inc. Alpha-synuclein kinase
EP2141163A1 (de) * 2008-07-02 2010-01-06 Bayer Schering Pharma AG Substituierte Thiazolidinone, deren Herstellung und Verwendung als Arzneimittel
JP5578705B2 (ja) * 2010-03-29 2014-08-27 公益財団法人相模中央化学研究所 （アリール）ジフルオロ酢酸エステル誘導体及びその製造方法
WO2014069434A1 (ja) * 2012-10-30 2014-05-08 カルナバイオサイエンス株式会社 新規チアゾリジノン誘導体
MX2015013348A (es) * 2013-03-20 2016-01-20 Bayer Pharma AG Derivados de 3-acetilamino-1 (fenil-heteroaril-aminocarbonil o fenil-heteroaril-carbonilamino) benceno para el tratamiento de desordenes hiperproliferativos.
CN105579457B (zh) * 2013-03-20 2017-08-04 拜耳制药股份公司 取代的n‑联苯‑3‑乙酰基氨基‑苯甲酰胺和n‑[3‑(乙酰基氨基)苯基]‑联苯‑甲酰胺及其作为wnt信号通路抑制剂用途
WO2015116696A1 (en) 2014-01-28 2015-08-06 Massachusetts Institute Of Technology Combination therapies and methods of use thereof for treating cancer
SG11201610478YA (en) * 2014-06-16 2017-01-27 Univ Lille Ii Droit & Sante Compounds, pharmaceutical composition and their use in treating neurodegenerative diseases
WO2023158514A1 (en) 2022-02-18 2023-08-24 Massachusetts Institute Of Technology Cancer treatment by combined inhibition of polo-like kinase and microtubule polymerization

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2004135533A (ru) * 2002-05-03 2005-07-20 Шеринг Акциенгезельшафт (De) Тиазолидиноны и их применение в качестве ингибиторов polo- подобной киназы
DE10351744A1 (de) * 2003-10-31 2005-06-16 Schering Ag Thiazolidinone, deren Herstellung und Verwendung als Arzneimittel

Also Published As

Publication number Publication date
CA2590396A1 (en) 2006-06-22
MX2007007245A (es) 2008-02-25
GT200500366A (es) 2006-12-04
BRPI0519040A2 (pt) 2009-01-13
AU2005315835A1 (en) 2006-06-22
US20100048891A1 (en) 2010-02-25
JP2008524139A (ja) 2008-07-10
TW200628458A (en) 2006-08-16
NO20073631L (no) 2007-09-12
EP1824834A1 (de) 2007-08-29
US20070015759A1 (en) 2007-01-18
IL183395A0 (en) 2007-09-20
CR9183A (es) 2008-01-21
PA8656501A1 (es) 2006-09-08
AR055698A1 (es) 2007-09-05
PE20061157A1 (es) 2006-11-16
WO2006063806A1 (de) 2006-06-22
KR20070092740A (ko) 2007-09-13

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Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20160606