NO20073932L - Fuserte bicykliske karboksamidderivater for anvendelse som CXCR2 inhibitorer i behandlingen av inflammasjon - Google Patents
Fuserte bicykliske karboksamidderivater for anvendelse som CXCR2 inhibitorer i behandlingen av inflammasjonInfo
- Publication number
- NO20073932L NO20073932L NO20073932A NO20073932A NO20073932L NO 20073932 L NO20073932 L NO 20073932L NO 20073932 A NO20073932 A NO 20073932A NO 20073932 A NO20073932 A NO 20073932A NO 20073932 L NO20073932 L NO 20073932L
- Authority
- NO
- Norway
- Prior art keywords
- treatment
- inflammation
- fused bicyclic
- carboxamide derivatives
- inhibitors
- Prior art date
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Abstract
Det er beskrevet forbindelser av formel (I) hvori RI, R2, X, A, B, D og Yl til Y4 har betydningene angitt i kravene, og/eller et farmasøytisk akseptabelt salt og/eller et promedikament derav. På grunn av deres egenskaper som inhibitorer av kjemokin-receptorer, spesielt som CXCR2 inhibitorer, er forbindelsene av formel I og de farmasøytisk akseptable saltene og promedikamentene derav egnede for forebyggelse og behandling av kjemokinformidlede lidelser, så som inflammatoriske sykdommer.
Applications Claiming Priority (2)
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EP04031009A EP1676834A1 (en) | 2004-12-30 | 2004-12-30 | Fused bicyclic carboxamide derivates for use as CXCR2 inhibitors in the treatment of inflammation |
PCT/EP2005/013624 WO2006069656A1 (en) | 2004-12-30 | 2005-12-17 | Fused bicyclic carboxamide derivatives for use as cxcr2 inhibitors in the treatment of inflammation |
Publications (1)
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NO20073932A NO20073932L (no) | 2004-12-30 | 2007-07-26 | Fuserte bicykliske karboksamidderivater for anvendelse som CXCR2 inhibitorer i behandlingen av inflammasjon |
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EP (2) | EP1676834A1 (no) |
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UY (1) | UY29322A1 (no) |
WO (1) | WO2006069656A1 (no) |
ZA (1) | ZA200704089B (no) |
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DE602007009865D1 (de) * | 2006-11-23 | 2010-11-25 | Novartis Ag | 5-sulfanylmethylä1,2,4ütriazolä1,5-aüpyrimidin-7-olderivate als cxcr2-antagonisten |
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CN101679346B (zh) * | 2007-06-05 | 2014-10-22 | 塞诺菲-安万特股份有限公司 | 取代的苯甲酰氨基茚满-2-羧酸及相关化合物 |
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JP6215924B2 (ja) * | 2012-06-19 | 2017-10-18 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | 新規の二環式チオフェニルアミド化合物 |
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CN105906608B (zh) * | 2016-05-03 | 2018-10-19 | 中山大学 | 8-氨基喹啉-松果体素杂联体及其药物组合物 |
CN106187974B (zh) * | 2016-07-01 | 2018-01-12 | 广州军区广州总医院 | 具有抗肿瘤作用的鱼藤素断环结构与氨基酸衍生物的合成方法 |
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- 2007-05-21 ZA ZA200704089A patent/ZA200704089B/xx unknown
- 2007-06-24 IL IL184173A patent/IL184173A/en unknown
- 2007-06-26 MA MA30032A patent/MA29113B1/fr unknown
- 2007-06-29 US US11/771,958 patent/US7919628B2/en not_active Expired - Fee Related
- 2007-07-26 NO NO20073932A patent/NO20073932L/no unknown
-
2011
- 2011-04-04 US US13/079,522 patent/US8283479B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
NZ556192A (en) | 2010-06-25 |
ZA200704089B (en) | 2008-09-25 |
US20080090854A1 (en) | 2008-04-17 |
US20110184177A1 (en) | 2011-07-28 |
JP5123667B2 (ja) | 2013-01-23 |
PE20060855A1 (es) | 2006-10-10 |
AU2005321609B2 (en) | 2011-02-17 |
IL184173A0 (en) | 2007-10-31 |
KR20070091634A (ko) | 2007-09-11 |
AU2005321609A1 (en) | 2006-07-06 |
TW200639141A (en) | 2006-11-16 |
AR055830A1 (es) | 2007-09-12 |
IL184173A (en) | 2011-10-31 |
RU2404962C2 (ru) | 2010-11-27 |
US7919628B2 (en) | 2011-04-05 |
BRPI0519452A2 (pt) | 2009-01-27 |
WO2006069656A1 (en) | 2006-07-06 |
EP1836158B1 (en) | 2012-02-01 |
CN101094830A (zh) | 2007-12-26 |
UY29322A1 (es) | 2006-07-31 |
CA2592430A1 (en) | 2006-07-06 |
ATE543795T1 (de) | 2012-02-15 |
EP1676834A1 (en) | 2006-07-05 |
EP1836158A1 (en) | 2007-09-26 |
JP2008526695A (ja) | 2008-07-24 |
MA29113B1 (fr) | 2007-12-03 |
US8283479B2 (en) | 2012-10-09 |
MX2007007068A (es) | 2007-08-08 |
RU2007128949A (ru) | 2009-02-10 |
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