NO20073802L - Leuprolidacetat og acetylkolinsteraseinhibitor eller NMDA-reseptorantagonister for behandlingen av Alzheimers sykdom - Google Patents
Leuprolidacetat og acetylkolinsteraseinhibitor eller NMDA-reseptorantagonister for behandlingen av Alzheimers sykdomInfo
- Publication number
- NO20073802L NO20073802L NO20073802A NO20073802A NO20073802L NO 20073802 L NO20073802 L NO 20073802L NO 20073802 A NO20073802 A NO 20073802A NO 20073802 A NO20073802 A NO 20073802A NO 20073802 L NO20073802 L NO 20073802L
- Authority
- NO
- Norway
- Prior art keywords
- alzheimer
- disease
- treatment
- acetylcholine
- receptor antagonists
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Endocrinology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Reproductive Health (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Hospice & Palliative Care (AREA)
- Diabetes (AREA)
- Toxicology (AREA)
- Psychiatry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US63812304P | 2004-12-23 | 2004-12-23 | |
PCT/US2005/024656 WO2006071274A2 (fr) | 2004-12-23 | 2005-07-13 | Acetate de leuprolide et inhibiteurs de l'acetylcholinesterase ou antagonistes des recepteurs nmda pour le traitement de la maladie d'alzheimer |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20073802L true NO20073802L (no) | 2007-09-24 |
Family
ID=36615349
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20073802A NO20073802L (no) | 2004-12-23 | 2007-07-20 | Leuprolidacetat og acetylkolinsteraseinhibitor eller NMDA-reseptorantagonister for behandlingen av Alzheimers sykdom |
Country Status (8)
Country | Link |
---|---|
US (2) | US20060142186A1 (fr) |
EP (3) | EP1827468B1 (fr) |
JP (1) | JP2008525439A (fr) |
CN (1) | CN101087618A (fr) |
AU (1) | AU2005322611A1 (fr) |
CA (1) | CA2590997A1 (fr) |
NO (1) | NO20073802L (fr) |
WO (1) | WO2006071274A2 (fr) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008055945A1 (fr) | 2006-11-09 | 2008-05-15 | Probiodrug Ag | Dérivés 3-hydr0xy-1,5-dihydr0-pyrr0l-2-one utiles en tant qu' inhibiteurs de la glutaminyl-cyclase dans le traitement des ulcères, du cancer et d'autres maladies |
ATE554085T1 (de) | 2006-11-30 | 2012-05-15 | Probiodrug Ag | Neue inhibitoren von glutaminylcyclase |
US20100028361A1 (en) * | 2006-12-19 | 2010-02-04 | Smith Mark A | Brain-derived gonadotropins and cognition |
EP2117540A1 (fr) | 2007-03-01 | 2009-11-18 | Probiodrug AG | Nouvelle utilisation d'inhibiteurs de la glutaminyl cyclase |
JP5667440B2 (ja) | 2007-04-18 | 2015-02-12 | プロビオドルグ エージー | グルタミニルシクラーゼ阻害剤としてのチオ尿素誘導体 |
SG178953A1 (en) | 2009-09-11 | 2012-04-27 | Probiodrug Ag | Heterocylcic derivatives as inhibitors of glutaminyl cyclase |
EP2533645B1 (fr) | 2010-02-09 | 2016-07-27 | The Johns Hopkins University | Procédés et compositions pour améliorer la fonction cognitive |
US9181233B2 (en) | 2010-03-03 | 2015-11-10 | Probiodrug Ag | Inhibitors of glutaminyl cyclase |
AU2011226074B2 (en) | 2010-03-10 | 2015-01-22 | Vivoryon Therapeutics N.V. | Heterocyclic inhibitors of glutaminyl cyclase (QC, EC 2.3.2.5) |
US8541596B2 (en) | 2010-04-21 | 2013-09-24 | Probiodrug Ag | Inhibitors |
ES2570167T3 (es) | 2011-03-16 | 2016-05-17 | Probiodrug Ag | Derivados de benzimidazol como inhibidores de glutaminil ciclasa |
EP2919788A4 (fr) | 2012-11-14 | 2016-05-25 | Univ Johns Hopkins | Méthodes et compositions pour le traitement de la schizophrénie |
US9339457B2 (en) | 2013-03-13 | 2016-05-17 | Transdermal Biotechnology, Inc. | Cardiovascular disease treatment and prevention |
US9314422B2 (en) | 2013-03-13 | 2016-04-19 | Transdermal Biotechnology, Inc. | Peptide systems and methods for metabolic conditions |
US9295647B2 (en) | 2013-03-13 | 2016-03-29 | Transdermal Biotechnology, Inc. | Systems and methods for delivery of peptides |
US9724419B2 (en) | 2013-03-13 | 2017-08-08 | Transdermal Biotechnology, Inc. | Peptide systems and methods for metabolic conditions |
US9849160B2 (en) | 2013-03-13 | 2017-12-26 | Transdermal Biotechnology, Inc. | Methods and systems for treating or preventing cancer |
US9750787B2 (en) * | 2013-03-13 | 2017-09-05 | Transdermal Biotechnology, Inc. | Memory or learning improvement using peptide and other compositions |
US20140271937A1 (en) * | 2013-03-13 | 2014-09-18 | Transdermal Biotechnology, Inc. | Brain and neural treatments comprising peptides and other compositions |
US9241899B2 (en) | 2013-03-13 | 2016-01-26 | Transdermal Biotechnology, Inc. | Topical systems and methods for treating sexual dysfunction |
US9387159B2 (en) | 2013-03-13 | 2016-07-12 | Transdermal Biotechnology, Inc. | Treatment of skin, including aging skin, to improve appearance |
US9687520B2 (en) | 2013-03-13 | 2017-06-27 | Transdermal Biotechnology, Inc. | Memory or learning improvement using peptide and other compositions |
US20140271938A1 (en) | 2013-03-13 | 2014-09-18 | Transdermal Biotechnology, Inc. | Systems and methods for delivery of peptides |
US9314433B2 (en) | 2013-03-13 | 2016-04-19 | Transdermal Biotechnology, Inc. | Methods and systems for treating or preventing cancer |
US9295636B2 (en) | 2013-03-13 | 2016-03-29 | Transdermal Biotechnology, Inc. | Wound healing using topical systems and methods |
US9320758B2 (en) | 2013-03-13 | 2016-04-26 | Transdermal Biotechnology, Inc. | Brain and neural treatments comprising peptides and other compositions |
US9320706B2 (en) | 2013-03-13 | 2016-04-26 | Transdermal Biotechnology, Inc. | Immune modulation using peptides and other compositions |
US9314423B2 (en) | 2013-03-13 | 2016-04-19 | Transdermal Biotechnology, Inc. | Hair treatment systems and methods using peptides and other compositions |
US9295637B2 (en) | 2013-03-13 | 2016-03-29 | Transdermal Biotechnology, Inc. | Compositions and methods for affecting mood states |
US9393264B2 (en) | 2013-03-13 | 2016-07-19 | Transdermal Biotechnology, Inc. | Immune modulation using peptides and other compositions |
US9314417B2 (en) | 2013-03-13 | 2016-04-19 | Transdermal Biotechnology, Inc. | Treatment of skin, including aging skin, to improve appearance |
US20140271731A1 (en) | 2013-03-13 | 2014-09-18 | Transdermal Biotechnology, Inc. | Cardiovascular disease treatment and prevention |
US9393265B2 (en) | 2013-03-13 | 2016-07-19 | Transdermal Biotechnology, Inc. | Wound healing using topical systems and methods |
EP2968237A4 (fr) | 2013-03-15 | 2016-08-31 | Univ Johns Hopkins | Procédés et compositions pour améliorer la fonction cognitive |
DK2968220T3 (da) | 2013-03-15 | 2021-06-14 | Agenebio Inc | Fremgangsmåder og sammensætninger til forbedring af kognitiv funktion |
BR112017025031B1 (pt) | 2015-05-22 | 2023-03-21 | Agenebio, Inc | Composições farmacêuticas de liberação prolongada de levetiracetam |
ES2812698T3 (es) | 2017-09-29 | 2021-03-18 | Probiodrug Ag | Inhibidores de glutaminil ciclasa |
CN108837143B (zh) * | 2018-09-29 | 2022-03-01 | 南华大学 | 曲普瑞林的应用 |
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US4005063A (en) * | 1973-10-11 | 1977-01-25 | Abbott Laboratories | [Des-gly]10 -GnRH nonapeptide anide analogs in position 6 having ovulation-inducing activity |
GB8600783D0 (en) * | 1986-01-14 | 1986-02-19 | Merck Sharp & Dohme | N-methyl-d-aspartate receptor antagonists |
US4663318A (en) * | 1986-01-15 | 1987-05-05 | Bonnie Davis | Method of treating Alzheimer's disease |
AU5186090A (en) * | 1989-02-23 | 1990-09-26 | Colorado State University Research Foundation | Gnrh analogs for destroying gonadotrophs |
US5693668A (en) * | 1989-06-22 | 1997-12-02 | Merrell Pharmaceuticals Inc. | Acetylcholinesterase inhibitors |
US5132313A (en) * | 1989-10-26 | 1992-07-21 | University Of Pittsburgh | Non-competitive NMDA receptor antagonists and methods for their use |
US5169932A (en) * | 1989-10-30 | 1992-12-08 | The Salk Institute For Biological Studies | Gnrh analogs |
CA2113115A1 (fr) * | 1991-07-29 | 1993-02-18 | Vlad E. Gregor | Derives de la quinazoline comme inhibiteurs de l'acethylcholinesterase |
TW263504B (fr) * | 1991-10-03 | 1995-11-21 | Pfizer | |
US5354758A (en) * | 1992-12-16 | 1994-10-11 | Japan Tobacco Inc. | Benzomorphans useful as NMDA receptor antagonists |
EP0627400A1 (fr) * | 1993-06-04 | 1994-12-07 | Merrell Dow Pharmaceuticals Inc. | Inhibiteurs aromatiques d'acétylcholinesterase |
US6316439B1 (en) * | 1993-10-15 | 2001-11-13 | Aventis Pharamaceuticals Inc. | Galanthamine derivatives as acetylcholinesterase inhibitors |
JPH07206619A (ja) * | 1994-01-26 | 1995-08-08 | Nematetsuku:Kk | 植物寄生性線虫防除用製剤及び防除方法 |
US6664369B1 (en) * | 1994-08-10 | 2003-12-16 | Creighton University | GnRH analogues with antitumour effects and pharmaceutical compositions thereof |
GB9418443D0 (en) * | 1994-09-13 | 1994-11-02 | Pfizer Ltd | Therapeutic agents |
GB9514448D0 (en) * | 1995-07-14 | 1995-09-13 | Iaf Biochem Int | Novel heterocyclic NMDA-receptor antagonists |
ES2100129B1 (es) * | 1995-10-11 | 1998-02-16 | Medichem Sa | Nuevos compuestos aminopiridinicos policiclicos inhibidores de acetilcolinesterasa, procedimiento para su preparacion y su utilizacion. |
ZA9610736B (en) * | 1995-12-22 | 1997-06-27 | Warner Lambert Co | 2-Substituted piperidine analogs and their use as subtypeselective nmda receptor antagonists |
US6100276A (en) * | 1996-04-12 | 2000-08-08 | Aventis Pharmaceuticals Inc. | Isatin derivatives as acetylcholinesterase inhibitors and analgesics |
AU1153097A (en) * | 1996-06-07 | 1998-01-05 | Eisai Co. Ltd. | Stable polymorphs of donepezil (1-benzyl-4-{(5,6-dimethoxy-1-indanon)-2-yl}methylpiperidine ) hydrochloride and process for production |
US6071966A (en) * | 1997-06-30 | 2000-06-06 | Merz + Co. Gmbh & Co. | 1-amino-alkylcyclohexane NMDA receptor antagonists |
AU744997B2 (en) * | 1997-09-05 | 2002-03-07 | Glaxo Group Limited | 2,3-diaryl-pyrazolo(1,5-B)pyridazines derivatives, their preparation and their use as cyclooxygenase 2 (COX-2) inhibitors |
US6242421B1 (en) * | 1997-11-06 | 2001-06-05 | Richard Lloyd Bowen | Methods for preventing and treating Alzheimer's disease |
PE20000728A1 (es) * | 1998-06-26 | 2000-08-21 | Cocensys Inc | Heterociclos 4-bencil piperidina alquilsulfoxido y su uso como antagonistas receptores subtipo-selectivo nmda |
JP2002521337A (ja) * | 1998-07-21 | 2002-07-16 | ユニバーシティ・カレッジ・ダブリン | ベンゾキノリジジン及びベンゾインドリジジンの誘導体、並びにその治療用途 |
EP1163220A1 (fr) * | 1999-03-23 | 2001-12-19 | Sumitomo Pharmaceuticals Company, Limited | Compose d'acide indole-2-carboxylique tricyclique utilise comme antagoniste du recepteur nmda |
US6833370B1 (en) * | 1999-05-21 | 2004-12-21 | Abbott Laboratories | Heterocycle substituted aminoazacycles useful as central nervous system agents |
WO2001009115A2 (fr) * | 1999-07-29 | 2001-02-08 | Eli Lilly And Company | NOUVELLE FORME CRISTALLINE DE CHLORHYDRATE DE 6-HYDROXY-3-(4-[2-(PIPERIDIN-E1-YL)ETHOXY]PHENOXY)-2-(4-METHOXYPHENYL)BENZO[b]THIOPHENE |
US6610706B1 (en) * | 1999-07-29 | 2003-08-26 | Eli Lilly And Company | Crystalline form of 6-hydroxy-3-(4-[2-(piperidin-1-yl)ethoxy]phenoxy)-2-(4-methoxyphenyl)benzo[b]thiophene hydrochloride |
DE19936719A1 (de) * | 1999-08-06 | 2001-02-15 | Gruenenthal Gmbh | Substituierte 1,5-Dihydropyrrol-2-on-Derivate |
US6323179B1 (en) * | 1999-10-15 | 2001-11-27 | Theresa Siler-Khodr | Chicken GNRH analogs and uses thereof in regulation of fertility and pregnancy |
US6635739B2 (en) * | 1999-10-15 | 2003-10-21 | Theresa Siler-Khodr | Non-mammalian GnRH analogs and uses thereof in regulation of fertility and pregnancy |
WO2001078728A1 (fr) * | 2000-04-13 | 2001-10-25 | Eisai Co., Ltd. | Inhibiteurs d'acetylcholinesterases contenant des sels de 1-benzyl-pyridinium |
KR20030007797A (ko) * | 2000-05-31 | 2003-01-23 | 워너-램버트 캄파니 | 바이시클릭 시클로헥실아민 및 nmda 수용체길항제로서의 그의 용도 |
WO2001092204A1 (fr) * | 2000-06-01 | 2001-12-06 | Warner-Lambert Company | Derives de cyclohexylamine utilises comme antagonistes des recepteurs n-methyl d-aspartate de nmda selectifs de sous-type. |
HU227197B1 (en) * | 2000-10-24 | 2010-10-28 | Richter Gedeon Nyrt | Nmda receptor antagonist carboxylic acid amide derivatives and pharmaceutical compositions containing them |
US7288517B2 (en) * | 2001-04-30 | 2007-10-30 | Aeterna Zentaris Gmbh | Treatment of dementia and neurodegenerative diseases with intermediate doses of LHRH antagonists |
EP1556019A2 (fr) * | 2002-10-24 | 2005-07-27 | Merz Pharma GmbH & Co. KGaA | Therapie combinee faisant appel a des derives de 1-aminocyclohexane ainsi qu'a des inhibiteurs d'acetylcholinesterase |
-
2005
- 2005-07-13 US US11/179,608 patent/US20060142186A1/en not_active Abandoned
- 2005-07-13 CN CNA2005800447705A patent/CN101087618A/zh active Pending
- 2005-07-13 EP EP05771273A patent/EP1827468B1/fr not_active Not-in-force
- 2005-07-13 WO PCT/US2005/024656 patent/WO2006071274A2/fr active Application Filing
- 2005-07-13 EP EP11181112A patent/EP2425845A1/fr not_active Withdrawn
- 2005-07-13 AU AU2005322611A patent/AU2005322611A1/en not_active Abandoned
- 2005-07-13 CA CA002590997A patent/CA2590997A1/fr not_active Abandoned
- 2005-07-13 EP EP11181114A patent/EP2425846A1/fr not_active Withdrawn
- 2005-07-13 JP JP2007548185A patent/JP2008525439A/ja active Pending
-
2007
- 2007-07-20 NO NO20073802A patent/NO20073802L/no not_active Application Discontinuation
- 2007-08-08 US US11/889,061 patent/US20080214639A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CA2590997A1 (fr) | 2006-07-06 |
US20080214639A1 (en) | 2008-09-04 |
EP2425846A1 (fr) | 2012-03-07 |
WO2006071274A3 (fr) | 2007-01-11 |
EP1827468A4 (fr) | 2009-08-05 |
EP1827468B1 (fr) | 2012-08-22 |
US20060142186A1 (en) | 2006-06-29 |
JP2008525439A (ja) | 2008-07-17 |
WO2006071274A2 (fr) | 2006-07-06 |
EP2425845A1 (fr) | 2012-03-07 |
EP1827468A2 (fr) | 2007-09-05 |
AU2005322611A1 (en) | 2006-07-06 |
CN101087618A (zh) | 2007-12-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |