NO20072158L - Mutert amyloidprotein - Google Patents
Mutert amyloidprotein Download PDFInfo
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- NO20072158L NO20072158L NO20072158A NO20072158A NO20072158L NO 20072158 L NO20072158 L NO 20072158L NO 20072158 A NO20072158 A NO 20072158A NO 20072158 A NO20072158 A NO 20072158A NO 20072158 L NO20072158 L NO 20072158L
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- Prior art keywords
- amyloid
- protein
- stated
- variant protein
- amino acids
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Classifications
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0007—Nervous system antigens; Prions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
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- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
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- Bioinformatics & Cheminformatics (AREA)
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- Epidemiology (AREA)
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- Hematology (AREA)
- Urology & Nephrology (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- General Chemical & Material Sciences (AREA)
- Mycology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- General Engineering & Computer Science (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2004294292 | 2004-10-06 | ||
| PCT/JP2005/018896 WO2006038729A1 (ja) | 2004-10-06 | 2005-10-06 | 変異型アミロイドタンパク質 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20072158L true NO20072158L (no) | 2007-07-05 |
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| Application Number | Title | Priority Date | Filing Date |
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| NO20072158A NO20072158L (no) | 2004-10-06 | 2007-04-26 | Mutert amyloidprotein |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20080063636A1 (zh) |
| EP (1) | EP1811025A4 (zh) |
| JP (1) | JP4776544B2 (zh) |
| KR (1) | KR20070100234A (zh) |
| CN (1) | CN101052718A (zh) |
| AU (1) | AU2005290401A1 (zh) |
| BR (1) | BRPI0516279A (zh) |
| CA (1) | CA2583431A1 (zh) |
| IL (1) | IL182404A0 (zh) |
| MX (1) | MX2007004149A (zh) |
| NO (1) | NO20072158L (zh) |
| NZ (1) | NZ554794A (zh) |
| RU (1) | RU2007116346A (zh) |
| WO (1) | WO2006038729A1 (zh) |
| ZA (1) | ZA200702869B (zh) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10303974A1 (de) | 2003-01-31 | 2004-08-05 | Abbott Gmbh & Co. Kg | Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung |
| CN101432302A (zh) | 2005-11-30 | 2009-05-13 | 艾博特公司 | 抗－Aβ球聚体抗体，其抗原结合部分，相应的杂交瘤、核酸、载体、宿主细胞，生产所述抗体的方法，包含所述抗体的组合物，所述抗体的应用以及使用所述抗体的方法 |
| CA2631195C (en) | 2005-11-30 | 2016-04-05 | Abbott Laboratories | Monoclonal antibodies against amyloid beta protein and uses thereof |
| US8455626B2 (en) | 2006-11-30 | 2013-06-04 | Abbott Laboratories | Aβ conformer selective anti-aβ globulomer monoclonal antibodies |
| EP2124952A2 (en) | 2007-02-27 | 2009-12-02 | Abbott GmbH & Co. KG | Method for the treatment of amyloidoses |
| US8987419B2 (en) | 2010-04-15 | 2015-03-24 | AbbVie Deutschland GmbH & Co. KG | Amyloid-beta binding proteins |
| MX358739B (es) | 2010-08-14 | 2018-09-03 | Abbvie Inc Star | Proteinas de union a amiloide beta. |
| WO2014126225A1 (ja) * | 2013-02-14 | 2014-08-21 | 公立大学法人大阪市立大学 | ノックインマウス |
| CA3220267A1 (en) | 2021-05-26 | 2022-12-01 | Kariem Ezzat Ahmed | Compositions and methods for treatment and/or prophylaxis of proteinopathies |
| WO2024071361A1 (ja) * | 2022-09-27 | 2024-04-04 | 株式会社カネカ | 凝集性タンパク質に対する凝集抑制活性又は凝集促進活性を評価する方法 |
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| US5338663A (en) * | 1990-08-24 | 1994-08-16 | President And Fellows Of Harvard College | Method of identifying inhibitors of β-protein esterase activity |
| WO2001090182A2 (en) * | 2000-05-22 | 2001-11-29 | New York University | Synthetic immunogenic but non-amyloidogenic peptides homologous to amyloid beta for induction of an immune response to amyloid beta and amyloid deposits |
| EP1572894B1 (en) * | 2001-11-21 | 2016-04-13 | New York University | Synthetic immunogenic but non-deposit-forming polypeptides and peptides homologous to amyloid beta, prion protein, amylin, alpha synuclein, or polyglutamine repeats for induction of an immune response thereto |
| AU2003256578A1 (en) * | 2002-07-17 | 2004-02-02 | Intellect Neurosciences, Inc. | Peptides and methods of screening immunogenic peptide vaccines against alzheimer's disease |
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2005
- 2005-10-06 US US11/664,714 patent/US20080063636A1/en not_active Abandoned
- 2005-10-06 EP EP05793045A patent/EP1811025A4/en not_active Withdrawn
- 2005-10-06 WO PCT/JP2005/018896 patent/WO2006038729A1/ja active Application Filing
- 2005-10-06 ZA ZA200702869A patent/ZA200702869B/xx unknown
- 2005-10-06 MX MX2007004149A patent/MX2007004149A/es unknown
- 2005-10-06 AU AU2005290401A patent/AU2005290401A1/en not_active Abandoned
- 2005-10-06 KR KR1020077007975A patent/KR20070100234A/ko not_active Application Discontinuation
- 2005-10-06 CN CNA2005800369299A patent/CN101052718A/zh active Pending
- 2005-10-06 BR BRPI0516279-3A patent/BRPI0516279A/pt not_active IP Right Cessation
- 2005-10-06 JP JP2006539359A patent/JP4776544B2/ja active Active
- 2005-10-06 NZ NZ554794A patent/NZ554794A/en unknown
- 2005-10-06 RU RU2007116346/13A patent/RU2007116346A/ru unknown
- 2005-10-06 CA CA002583431A patent/CA2583431A1/en not_active Abandoned
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2007
- 2007-04-10 IL IL182404A patent/IL182404A0/en unknown
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Also Published As
| Publication number | Publication date |
|---|---|
| MX2007004149A (es) | 2007-09-11 |
| EP1811025A4 (en) | 2008-02-06 |
| US20080063636A1 (en) | 2008-03-13 |
| RU2007116346A (ru) | 2008-11-20 |
| EP1811025A1 (en) | 2007-07-25 |
| AU2005290401A1 (en) | 2006-04-13 |
| IL182404A0 (en) | 2007-07-24 |
| NZ554794A (en) | 2010-01-29 |
| KR20070100234A (ko) | 2007-10-10 |
| JPWO2006038729A1 (ja) | 2008-05-15 |
| BRPI0516279A (pt) | 2008-09-02 |
| CN101052718A (zh) | 2007-10-10 |
| ZA200702869B (en) | 2008-07-30 |
| WO2006038729A1 (ja) | 2006-04-13 |
| JP4776544B2 (ja) | 2011-09-21 |
| CA2583431A1 (en) | 2006-04-13 |
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