ZA200702869B - Mutated amyloid protein - Google Patents
Mutated amyloid proteinInfo
- Publication number
- ZA200702869B ZA200702869B ZA200702869A ZA200702869A ZA200702869B ZA 200702869 B ZA200702869 B ZA 200702869B ZA 200702869 A ZA200702869 A ZA 200702869A ZA 200702869 A ZA200702869 A ZA 200702869A ZA 200702869 B ZA200702869 B ZA 200702869B
- Authority
- ZA
- South Africa
- Prior art keywords
- amyloid protein
- mutated amyloid
- mutated
- protein
- amyloid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0007—Nervous system antigens; Prions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Neurology (AREA)
- Genetics & Genomics (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Mycology (AREA)
- Toxicology (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Analytical Chemistry (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2004294292 | 2004-10-06 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200702869B true ZA200702869B (en) | 2008-07-30 |
Family
ID=36142786
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200702869A ZA200702869B (en) | 2004-10-06 | 2005-10-06 | Mutated amyloid protein |
Country Status (15)
Country | Link |
---|---|
US (1) | US20080063636A1 (xx) |
EP (1) | EP1811025A4 (xx) |
JP (1) | JP4776544B2 (xx) |
KR (1) | KR20070100234A (xx) |
CN (1) | CN101052718A (xx) |
AU (1) | AU2005290401A1 (xx) |
BR (1) | BRPI0516279A (xx) |
CA (1) | CA2583431A1 (xx) |
IL (1) | IL182404A0 (xx) |
MX (1) | MX2007004149A (xx) |
NO (1) | NO20072158L (xx) |
NZ (1) | NZ554794A (xx) |
RU (1) | RU2007116346A (xx) |
WO (1) | WO2006038729A1 (xx) |
ZA (1) | ZA200702869B (xx) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10303974A1 (de) | 2003-01-31 | 2004-08-05 | Abbott Gmbh & Co. Kg | Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung |
KR20080090408A (ko) | 2005-11-30 | 2008-10-08 | 아보트 러보러터리즈 | 항-Aβ 글로불로머 항체, 이의 항원-결합 잔기, 상응하는하이브리도마, 핵산, 벡터, 숙주 세포, 당해 항체의 제조방법, 당해 항체를 포함하는 조성물, 당해 항체의 용도 및당해 항체의 사용 방법 |
DK1976877T4 (en) | 2005-11-30 | 2017-01-16 | Abbvie Inc | Monoclonal antibodies to amyloid beta protein and uses thereof |
US8455626B2 (en) | 2006-11-30 | 2013-06-04 | Abbott Laboratories | Aβ conformer selective anti-aβ globulomer monoclonal antibodies |
US20100311767A1 (en) | 2007-02-27 | 2010-12-09 | Abbott Gmbh & Co. Kg | Method for the treatment of amyloidoses |
JP2013523182A (ja) | 2010-04-15 | 2013-06-17 | アボット・ラボラトリーズ | アミロイドベータ結合タンパク質 |
CN105348387B (zh) | 2010-08-14 | 2020-08-25 | Abbvie 公司 | β淀粉样蛋白结合蛋白 |
WO2014126225A1 (ja) * | 2013-02-14 | 2014-08-21 | 公立大学法人大阪市立大学 | ノックインマウス |
KR20240013764A (ko) | 2021-05-26 | 2024-01-30 | 리게인 테라퓨틱스 스웨덴 에이비 | 단백질병증의 치료 및/또는 예방을 위한 조성물 및 방법 |
WO2024071361A1 (ja) * | 2022-09-27 | 2024-04-04 | 株式会社カネカ | 凝集性タンパク質に対する凝集抑制活性又は凝集促進活性を評価する方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5338663A (en) * | 1990-08-24 | 1994-08-16 | President And Fellows Of Harvard College | Method of identifying inhibitors of β-protein esterase activity |
JP2003534351A (ja) * | 2000-05-22 | 2003-11-18 | ニュー・ヨーク・ユニヴァーシティー | アミロイドβ及びアミロイド沈着物に対する免疫応答誘導のための、アミロイドβと相同的な、合成の、免疫原性だが非アミロイド原性ペプチド |
US7479482B2 (en) * | 2001-11-21 | 2009-01-20 | New York University | Synthetic immunogenic but non-deposit-forming polypeptides and peptides homologous to amyloid β, prion protein, amylin, α-synuclein, or polyglutamine repeats for induction of an immune response thereto |
EP1575529A4 (en) * | 2002-07-17 | 2007-08-08 | Intellect Neurosciences Inc | PEPTIDES AND METHOD FOR THE INVESTIGATION OF IMMUNOGENOUS PEPTIDE VACCINES AGAINST ALZHEIMER DISEASE |
-
2005
- 2005-10-06 JP JP2006539359A patent/JP4776544B2/ja active Active
- 2005-10-06 BR BRPI0516279-3A patent/BRPI0516279A/pt not_active IP Right Cessation
- 2005-10-06 AU AU2005290401A patent/AU2005290401A1/en not_active Abandoned
- 2005-10-06 CA CA002583431A patent/CA2583431A1/en not_active Abandoned
- 2005-10-06 US US11/664,714 patent/US20080063636A1/en not_active Abandoned
- 2005-10-06 RU RU2007116346/13A patent/RU2007116346A/ru unknown
- 2005-10-06 NZ NZ554794A patent/NZ554794A/en unknown
- 2005-10-06 EP EP05793045A patent/EP1811025A4/en not_active Withdrawn
- 2005-10-06 CN CNA2005800369299A patent/CN101052718A/zh active Pending
- 2005-10-06 MX MX2007004149A patent/MX2007004149A/es unknown
- 2005-10-06 ZA ZA200702869A patent/ZA200702869B/xx unknown
- 2005-10-06 WO PCT/JP2005/018896 patent/WO2006038729A1/ja active Application Filing
- 2005-10-06 KR KR1020077007975A patent/KR20070100234A/ko not_active Application Discontinuation
-
2007
- 2007-04-10 IL IL182404A patent/IL182404A0/en unknown
- 2007-04-26 NO NO20072158A patent/NO20072158L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
JPWO2006038729A1 (ja) | 2008-05-15 |
JP4776544B2 (ja) | 2011-09-21 |
CN101052718A (zh) | 2007-10-10 |
RU2007116346A (ru) | 2008-11-20 |
AU2005290401A1 (en) | 2006-04-13 |
WO2006038729A1 (ja) | 2006-04-13 |
IL182404A0 (en) | 2007-07-24 |
NO20072158L (no) | 2007-07-05 |
EP1811025A1 (en) | 2007-07-25 |
MX2007004149A (es) | 2007-09-11 |
BRPI0516279A (pt) | 2008-09-02 |
KR20070100234A (ko) | 2007-10-10 |
US20080063636A1 (en) | 2008-03-13 |
NZ554794A (en) | 2010-01-29 |
EP1811025A4 (en) | 2008-02-06 |
CA2583431A1 (en) | 2006-04-13 |
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