NO20071208L - Trisykliske 5-opioidmodulatorer - Google Patents

Trisykliske 5-opioidmodulatorer

Info

Publication number
NO20071208L
NO20071208L NO20071208A NO20071208A NO20071208L NO 20071208 L NO20071208 L NO 20071208L NO 20071208 A NO20071208 A NO 20071208A NO 20071208 A NO20071208 A NO 20071208A NO 20071208 L NO20071208 L NO 20071208L
Authority
NO
Norway
Prior art keywords
tricyclic
modulators
opioid
opioid modulators
pharmaceutical
Prior art date
Application number
NO20071208A
Other languages
English (en)
Inventor
Li Liu
Scott L Dax
Bart Decorte
Mark Mcdonnell
James J Mcnally
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of NO20071208L publication Critical patent/NO20071208L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Oppfinnelsen er rettet mot delta-opioidreseptormodulatorer. Mer spesielt angår oppfinnelsen tricykliske ?-opioidmodulatorer. Farmasøytiske og veterinærpreparater og metoder for behandling av mild til sterk smerte og forskjellige sykdommer som anvender forbindelser ifølge oppfinnelsen er også beskrevet.
NO20071208A 2004-08-05 2007-03-05 Trisykliske 5-opioidmodulatorer NO20071208L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US59913104P 2004-08-05 2004-08-05
PCT/US2005/027568 WO2007030089A1 (en) 2004-08-05 2005-08-02 Tricyclic delta- opioid modulators

Publications (1)

Publication Number Publication Date
NO20071208L true NO20071208L (no) 2007-04-19

Family

ID=37075386

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20071208A NO20071208L (no) 2004-08-05 2007-03-05 Trisykliske 5-opioidmodulatorer

Country Status (17)

Country Link
US (2) US7553850B2 (no)
EP (1) EP1910353A1 (no)
JP (1) JP2008529971A (no)
KR (1) KR20080027216A (no)
CN (1) CN101039940A (no)
AR (1) AR050198A1 (no)
AU (1) AU2005335481A1 (no)
BR (1) BRPI0513075A (no)
CA (1) CA2574768A1 (no)
EA (1) EA200700403A1 (no)
EC (1) ECSP077230A (no)
IL (1) IL181120A0 (no)
NI (1) NI200700030A (no)
NO (1) NO20071208L (no)
TW (1) TW200621767A (no)
WO (1) WO2007030089A1 (no)
ZA (1) ZA200701875B (no)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7589103B2 (en) 2003-06-27 2009-09-15 Janssen Pharmaceutica N.V. Tricyclic-bridged piperidinylidene derivatives as 8-opioid modulators
AU2005335481A1 (en) 2004-08-05 2007-04-19 Janssen Pharmaceutica N.V. Tricyclic delta- opioid modulators
CN101115751A (zh) * 2004-12-22 2008-01-30 詹森药业有限公司 三环δ-阿片样物质调节剂
KR20070092286A (ko) * 2004-12-22 2007-09-12 얀센 파마슈티카 엔.브이. 트리사이클릭 델타-오피오이드 조절제
EP1833825A1 (en) * 2004-12-22 2007-09-19 Janssen Pharmaceutica N.V. Tricyclic delta-opioid modulators
US7432257B2 (en) * 2005-01-06 2008-10-07 Janssen Pharmaceutica N.V. Piperdinyl-phenoxazine and phenothiazine derivatives as δ-opioid modulators
BRPI0611885A2 (pt) * 2005-06-16 2010-10-05 Janssen Pharmaceutica Nv moduladores opióides tricìclicos
CA2615774C (en) 2005-07-21 2014-12-09 Rensselaer Polytechnic Institute Large substituent, non-phenolic opioids
EP2725908B1 (en) 2011-06-29 2017-05-31 Alkermes, Inc. Peripherally acting opioid compounds
WO2018083635A2 (en) 2016-11-04 2018-05-11 Auckland Uniservices Limited Tricyclic heterocyclic derivatives and uses thereof

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US2901478A (en) 1957-02-11 1959-08-25 Promonta Chem Fab Phenothiazine compounds
US3179665A (en) 1959-12-16 1965-04-20 Wander Ag Dr A 9-(n-ethyl and n-propyl piperidyl-3'-methyl)-thioxanthenes
DE1159954B (de) 1961-11-25 1963-12-27 Boehringer & Soehne Gmbh Verfahren zur Herstellung neuer 10-(Alkoxypiperidinopropyl)-phenthiazine und ihrer Salze
DE1670118A1 (de) 1966-07-22 1970-11-05 Boehringer Mannheim Gmbh Verfahren zur Herstellung neuer Derivate des 6,11-Dihydro-dibenz[b,e]oxepins und ihrer Salze
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US7589103B2 (en) * 2003-06-27 2009-09-15 Janssen Pharmaceutica N.V. Tricyclic-bridged piperidinylidene derivatives as 8-opioid modulators
AU2005335481A1 (en) 2004-08-05 2007-04-19 Janssen Pharmaceutica N.V. Tricyclic delta- opioid modulators
EP1833825A1 (en) * 2004-12-22 2007-09-19 Janssen Pharmaceutica N.V. Tricyclic delta-opioid modulators
KR20070092286A (ko) 2004-12-22 2007-09-12 얀센 파마슈티카 엔.브이. 트리사이클릭 델타-오피오이드 조절제
CN101115751A (zh) 2004-12-22 2008-01-30 詹森药业有限公司 三环δ-阿片样物质调节剂
US7432257B2 (en) * 2005-01-06 2008-10-07 Janssen Pharmaceutica N.V. Piperdinyl-phenoxazine and phenothiazine derivatives as δ-opioid modulators
BRPI0611885A2 (pt) * 2005-06-16 2010-10-05 Janssen Pharmaceutica Nv moduladores opióides tricìclicos

Also Published As

Publication number Publication date
AR050198A1 (es) 2006-10-04
EP1910353A1 (en) 2008-04-16
BRPI0513075A (pt) 2008-04-22
KR20080027216A (ko) 2008-03-26
ZA200701875B (en) 2008-07-30
EA200700403A1 (ru) 2007-08-31
NI200700030A (es) 2008-02-04
US20060030585A1 (en) 2006-02-09
WO2007030089A8 (en) 2007-05-31
AU2005335481A8 (en) 2008-12-11
AU2005335481A1 (en) 2007-04-19
TW200621767A (en) 2006-07-01
US7553850B2 (en) 2009-06-30
JP2008529971A (ja) 2008-08-07
CA2574768A1 (en) 2006-02-05
US20090291979A1 (en) 2009-11-26
IL181120A0 (en) 2008-03-20
CN101039940A (zh) 2007-09-19
ECSP077230A (es) 2007-04-26
WO2007030089A1 (en) 2007-03-15

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