NO20070874L - Sammensetning for a fremme vaskulaer glattt muskelavslapping. - Google Patents

Sammensetning for a fremme vaskulaer glattt muskelavslapping.

Info

Publication number
NO20070874L
NO20070874L NO20070874A NO20070874A NO20070874L NO 20070874 L NO20070874 L NO 20070874L NO 20070874 A NO20070874 A NO 20070874A NO 20070874 A NO20070874 A NO 20070874A NO 20070874 L NO20070874 L NO 20070874L
Authority
NO
Norway
Prior art keywords
composition
vasodilator
active ingredient
volatile
saturated
Prior art date
Application number
NO20070874A
Other languages
English (en)
Inventor
Adrian Francis Davis
Original Assignee
Futura Medical Dev Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Futura Medical Dev Ltd filed Critical Futura Medical Dev Ltd
Publication of NO20070874L publication Critical patent/NO20070874L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Endocrinology (AREA)
  • Vascular Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

En sammensetning for topisk påføring på en del av kroppen omfatter en vasodilator, for eksempel glyceryl trinitrat, som aktiv ingrediens oppløst i en blanding av flyktige og ikke-flyktige oppløsningsmidler med forskjellige oppløsende evner for vasodilatoren. Vasodilatoren er til stede i sammensetningen ved en konsentrasjon ved eller svakt under metning, hvorved inndamping av det flyktige oppløsningsmidlet i bruk vil opprettholde vasodilatoren ved mettet eller supemettede konsentrasjoner i resten, hvorved vasodilatoren vil bli mettet eller supermettet i det gjenværende oppløsningsmidlet, og når den aktive komponenten passerer gjennom huden og blir absorbert i blodstrømmen, og blir således uttømt i den resterende sammensetningen, vil fortsatt inndamping av flyktig oppløsningsmiddel opprettholde den aktive ingrediensen hovedsakelig ved metning eller supermetningsnivå i den resterende sammensetningen gjennom hoveddelen av absorpsjonsfasen, for dermed maksimalisere absorpsjonsnivåene, men ved et moderat doseringsnivå.
NO20070874A 2004-08-09 2007-02-15 Sammensetning for a fremme vaskulaer glattt muskelavslapping. NO20070874L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0417675.6A GB0417675D0 (en) 2004-08-09 2004-08-09 Composition for promoting vascular smooth muscle relaxation
PCT/GB2005/003110 WO2006016139A1 (en) 2004-08-09 2005-08-08 Composition for promoting vascular smooth muscle relaxation

Publications (1)

Publication Number Publication Date
NO20070874L true NO20070874L (no) 2007-02-15

Family

ID=32982731

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20070874A NO20070874L (no) 2004-08-09 2007-02-15 Sammensetning for a fremme vaskulaer glattt muskelavslapping.

Country Status (20)

Country Link
US (1) US8951553B2 (no)
EP (1) EP1786468B1 (no)
JP (1) JP2008509208A (no)
KR (1) KR101204397B1 (no)
CN (1) CN101022832A (no)
AT (1) ATE433761T1 (no)
AU (1) AU2005271049B2 (no)
BR (1) BRPI0513991A (no)
CA (1) CA2573386C (no)
DE (1) DE602005014999D1 (no)
ES (1) ES2328380T3 (no)
GB (1) GB0417675D0 (no)
IL (1) IL180577A0 (no)
MX (1) MX2007001639A (no)
NO (1) NO20070874L (no)
NZ (1) NZ552789A (no)
RU (1) RU2407519C2 (no)
TW (1) TWI371273B (no)
WO (1) WO2006016139A1 (no)
ZA (1) ZA200700193B (no)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0602224D0 (en) * 2006-02-03 2006-03-15 Futura Medical Dev Ltd Composition for promoting vascular smooth muscle relaxation
GB201713160D0 (en) * 2017-08-16 2017-09-27 Futura Medical Dev Ltd Topical composition
CN109276565A (zh) * 2018-10-19 2019-01-29 太阳雨林（厦门）生物医药有限公司 硝化甘油在制备治疗慢性肢体缺血性疾病药物中的应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4704119A (en) * 1983-02-03 1987-11-03 Alza Corporation Method comprising transdermal and buccal treatment of angina
HU199678B (en) * 1988-07-08 1990-03-28 Egyt Gyogyszervegyeszeti Gyar Process for producing aerosols containing nitroglicerol
US5370862A (en) * 1990-06-13 1994-12-06 Schwarz Pharma Ag Pharmaceutical hydrophilic spray containing nitroglycerin for treating angina
DE4018919C2 (de) 1990-06-13 1994-08-25 Sanol Arznei Schwarz Gmbh Nitroglycerin-Spray
DE4026072A1 (de) 1990-08-17 1992-02-20 Sanol Arznei Schwarz Gmbh Nitroglycerinhaltiger, hydrophiler, waessriger pumpspray
WO1994002119A1 (en) 1992-07-23 1994-02-03 Hisamitsu Pharmaceutical Co., Inc. Percutaneously administrable base composition and drug composition prepared therefrom
US5807569A (en) * 1993-05-27 1998-09-15 Smithkline Beecham P.L.C. Topical composition
US5698589A (en) * 1993-06-01 1997-12-16 International Medical Innovations, Inc. Water-based topical cream containing nitroglycerin and method of preparation and use thereof
GB9802078D0 (en) * 1998-01-30 1998-03-25 Futura Medical Limited Preparation for treatment of erectile dysfunction

Also Published As

Publication number Publication date
EP1786468B1 (en) 2009-06-17
ES2328380T3 (es) 2009-11-12
IL180577A0 (en) 2007-06-03
CA2573386A1 (en) 2006-02-16
AU2005271049A1 (en) 2006-02-16
BRPI0513991A (pt) 2008-05-20
KR101204397B1 (ko) 2012-11-26
US20080081058A1 (en) 2008-04-03
TWI371273B (en) 2012-09-01
CN101022832A (zh) 2007-08-22
RU2407519C2 (ru) 2010-12-27
DE602005014999D1 (de) 2009-07-30
WO2006016139A1 (en) 2006-02-16
TW200605874A (en) 2006-02-16
CA2573386C (en) 2013-10-01
ZA200700193B (en) 2009-03-25
ATE433761T1 (de) 2009-07-15
EP1786468A1 (en) 2007-05-23
KR20070054631A (ko) 2007-05-29
AU2005271049B2 (en) 2011-08-04
US8951553B2 (en) 2015-02-10
JP2008509208A (ja) 2008-03-27
MX2007001639A (es) 2007-04-24
NZ552789A (en) 2010-12-24
RU2007106941A (ru) 2008-09-20
GB0417675D0 (en) 2004-09-08

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