NO20070114L - Fremstilling av makromolekylaere konjugater ved firekomponent kondensasjonsreaksjon - Google Patents
Fremstilling av makromolekylaere konjugater ved firekomponent kondensasjonsreaksjonInfo
- Publication number
- NO20070114L NO20070114L NO20070114A NO20070114A NO20070114L NO 20070114 L NO20070114 L NO 20070114L NO 20070114 A NO20070114 A NO 20070114A NO 20070114 A NO20070114 A NO 20070114A NO 20070114 L NO20070114 L NO 20070114L
- Authority
- NO
- Norway
- Prior art keywords
- conjugates
- condensation reaction
- preparation
- component condensation
- macromolecular conjugates
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/785—Polymers containing nitrogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Polyethers (AREA)
- Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US57819904P | 2004-06-08 | 2004-06-08 | |
PCT/US2005/020138 WO2005123140A2 (fr) | 2004-06-08 | 2005-06-08 | Preparation de conjugues macromoleculaires par reaction de condensation a quatre composants |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20070114L true NO20070114L (no) | 2007-01-08 |
Family
ID=35355954
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20070114A NO20070114L (no) | 2004-06-08 | 2007-01-08 | Fremstilling av makromolekylaere konjugater ved firekomponent kondensasjonsreaksjon |
Country Status (12)
Country | Link |
---|---|
US (1) | US7476725B2 (fr) |
EP (1) | EP1761282A2 (fr) |
JP (1) | JP2008502788A (fr) |
KR (1) | KR20070027621A (fr) |
CN (1) | CN1997401A (fr) |
AU (1) | AU2005253979A1 (fr) |
CA (1) | CA2568388A1 (fr) |
IL (1) | IL179303A0 (fr) |
MX (1) | MXPA06014307A (fr) |
NO (1) | NO20070114L (fr) |
WO (1) | WO2005123140A2 (fr) |
ZA (1) | ZA200609930B (fr) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8470315B2 (en) | 2004-04-13 | 2013-06-25 | Quintessence Biosciences, Inc. | Non-natural ribonuclease conjugates as cytotoxic agents |
EP2007538A4 (fr) * | 2006-03-31 | 2011-04-20 | Centocor Ortho Biotech Inc | Partenaires de liaison présentant des domaines d'immunoglobuline modifiés pour avoir une demi-vie plus longue |
WO2007140282A1 (fr) * | 2006-05-24 | 2007-12-06 | Peg Biosciences | Composés de lieurs à base de polyéthylène glycol et conjugués biologiquement actifs à base desdits composés |
WO2007149594A2 (fr) | 2006-06-23 | 2007-12-27 | Quintessence Biosciences, Inc. | Ribonucléases modifiées |
US9175061B2 (en) | 2006-07-07 | 2015-11-03 | Novo Nordisk Health Care Ag | Protein conjugates and methods for their preparation |
WO2008010991A2 (fr) * | 2006-07-17 | 2008-01-24 | Quintessence Biosciences, Inc. | Méthodes et compositions pour le traitement du cancer |
JP2010540681A (ja) | 2007-10-08 | 2010-12-24 | クインテッセンス バイオサイエンシズ,インコーポレーテッド | リボヌクレアーゼに基づく治療のための組成物及び方法 |
KR100967833B1 (ko) * | 2008-05-20 | 2010-07-05 | 아이디비켐(주) | 고순도의 폴리에틸렌글리콜 알데하이드 유도체의 제조방법 |
WO2010039985A1 (fr) | 2008-10-01 | 2010-04-08 | Quintessence Biosciences, Inc. | Ribonucléases thérapeutiques |
RU2617402C2 (ru) | 2011-06-10 | 2017-04-25 | Мерсана Терапьютикс, Инк. | Конъюгаты белок-полимер-лекарственное средство |
US8815226B2 (en) | 2011-06-10 | 2014-08-26 | Mersana Therapeutics, Inc. | Protein-polymer-drug conjugates |
JP5841768B2 (ja) * | 2011-08-05 | 2016-01-13 | 花王株式会社 | 脂肪蓄積抑制剤 |
Family Cites Families (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4179337A (en) * | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
US4917888A (en) * | 1985-06-26 | 1990-04-17 | Cetus Corporation | Solubilization of immunotoxins for pharmaceutical compositions using polymer conjugation |
US4766106A (en) * | 1985-06-26 | 1988-08-23 | Cetus Corporation | Solubilization of proteins for pharmaceutical compositions using polymer conjugation |
US5103556A (en) * | 1988-05-05 | 1992-04-14 | Circon Corporation | Method of manufacturing an electrohydraulic probe |
US4902502A (en) * | 1989-01-23 | 1990-02-20 | Cetus Corporation | Preparation of a polymer/interleukin-2 conjugate |
DE69033192T3 (de) | 1989-04-19 | 2004-05-19 | Enzon, Inc. | Aktive karbonate von polyalkylenoxyden zur modifizierung von polypeptiden |
DE69026306T2 (de) * | 1989-05-27 | 1996-10-17 | Seikagaku Kogyo Co Ltd | Verfahren für die Herstellung von Polyethylenglykolderivate und modifizierte Proteine. |
JP3202744B2 (ja) * | 1989-05-27 | 2001-08-27 | 住友製薬株式会社 | ポリエチレングリコール誘導体を含有する蛋白質修飾試薬 |
US5286637A (en) * | 1989-08-07 | 1994-02-15 | Debiopharm, S.A. | Biologically active drug polymer derivatives and method for preparing same |
WO1992016555A1 (fr) | 1991-03-18 | 1992-10-01 | Enzon, Inc. | Conjuges de polypeptides et de glycopolypeptides associes a des polymeres, contenant de l'hydrazine |
US5395619A (en) * | 1993-03-03 | 1995-03-07 | Liposome Technology, Inc. | Lipid-polymer conjugates and liposomes |
US5932462A (en) * | 1995-01-10 | 1999-08-03 | Shearwater Polymers, Inc. | Multiarmed, monofunctional, polymer for coupling to molecules and surfaces |
SE9503380D0 (sv) * | 1995-09-29 | 1995-09-29 | Pharmacia Ab | Protein derivatives |
JP4410852B2 (ja) * | 1996-08-02 | 2010-02-03 | オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド | 単一の共有結合n末端水溶性ポリマーを有するポリペプチド |
DE19636538A1 (de) | 1996-09-09 | 1998-03-12 | Bayer Ag | Substituierte Aminosäurederivate |
DE59810914D1 (de) | 1997-05-14 | 2004-04-08 | Morphochem Ag | Verfahren zur herstellung von polymeren, die nucleobasen als seitengruppen aufweisen |
US6043221A (en) * | 1997-07-30 | 2000-03-28 | Amgen Inc. | Method for preventing and treating hearing loss using a neuturin protein product |
JP2000146971A (ja) * | 1998-11-10 | 2000-05-26 | Nisshinbo Ind Inc | 生物学的活性物質の固定化用担体 |
TW476231B (en) * | 1998-11-30 | 2002-02-11 | Omron Tateisi Electronics Co | Electronic machine |
SE519326C2 (sv) | 1999-11-22 | 2003-02-11 | Astrazeneca Ab | Funktionaliserade polymera reagens innefattande en syralabil isonitrildel samt förfarande för dess framställning |
JP2003535208A (ja) * | 2000-06-08 | 2003-11-25 | ラ ホヤ ファーマシューティカル カンパニー | 高分子量ポリエチレン・オキシドを含む多価プラットホーム分子 |
DE10150077B4 (de) | 2001-10-10 | 2004-07-29 | Morphochem Aktiengesellschaft für kombinatorische Chemie | Verfahren zur Herstellung polymergebundener Isonitrile |
DE10162134A1 (de) | 2001-12-18 | 2003-07-10 | Morphochem Ag Ag Fuer Kombinat | Harzgebundene Isonitrile |
DE10326303A1 (de) | 2003-06-11 | 2004-12-30 | Celares Gmbh | Reagenzien zur Modifikation von Biopharmazeutika, deren Herstellung und Anwendung |
JP2005146068A (ja) * | 2003-11-13 | 2005-06-09 | Japan Science & Technology Agency | アルコキシアセチル基を構成するカルボン酸修飾されたモノメチルエーテルポリエチレングリコールポリマーの利用、前記ポリマーからの誘導体化合物類 |
-
2005
- 2005-06-08 EP EP05757910A patent/EP1761282A2/fr not_active Withdrawn
- 2005-06-08 US US11/148,122 patent/US7476725B2/en not_active Expired - Fee Related
- 2005-06-08 CA CA002568388A patent/CA2568388A1/fr not_active Abandoned
- 2005-06-08 AU AU2005253979A patent/AU2005253979A1/en not_active Abandoned
- 2005-06-08 WO PCT/US2005/020138 patent/WO2005123140A2/fr active Application Filing
- 2005-06-08 KR KR1020067027339A patent/KR20070027621A/ko not_active Application Discontinuation
- 2005-06-08 JP JP2007527690A patent/JP2008502788A/ja active Pending
- 2005-06-08 MX MXPA06014307A patent/MXPA06014307A/es unknown
- 2005-06-08 CN CNA2005800188344A patent/CN1997401A/zh active Pending
- 2005-06-08 ZA ZA200609930A patent/ZA200609930B/xx unknown
-
2006
- 2006-11-15 IL IL179303A patent/IL179303A0/en unknown
-
2007
- 2007-01-08 NO NO20070114A patent/NO20070114L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
EP1761282A2 (fr) | 2007-03-14 |
CN1997401A (zh) | 2007-07-11 |
WO2005123140A3 (fr) | 2006-08-03 |
US20050287113A1 (en) | 2005-12-29 |
US7476725B2 (en) | 2009-01-13 |
IL179303A0 (en) | 2007-03-08 |
CA2568388A1 (fr) | 2005-12-29 |
WO2005123140A2 (fr) | 2005-12-29 |
KR20070027621A (ko) | 2007-03-09 |
AU2005253979A1 (en) | 2005-12-29 |
MXPA06014307A (es) | 2007-03-12 |
ZA200609930B (en) | 2009-01-28 |
JP2008502788A (ja) | 2008-01-31 |
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Legal Events
Date | Code | Title | Description |
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FC2A | Withdrawal, rejection or dismissal of laid open patent application |