NO20065319L - Piperidinderivater som modulatorer for kjemokinreseptor CCR5 - Google Patents

Piperidinderivater som modulatorer for kjemokinreseptor CCR5

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Publication number
NO20065319L
NO20065319L NO20065319A NO20065319A NO20065319L NO 20065319 L NO20065319 L NO 20065319L NO 20065319 A NO20065319 A NO 20065319A NO 20065319 A NO20065319 A NO 20065319A NO 20065319 L NO20065319 L NO 20065319L
Authority
NO
Norway
Prior art keywords
modulators
chemokine receptor
piperidine derivatives
receptor ccr5
ccr5
Prior art date
Application number
NO20065319A
Other languages
English (en)
Inventor
Alan Faull
Howard Tucker
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35197429&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20065319(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from SE0401057A external-priority patent/SE0401057D0/xx
Priority claimed from SE0500057A external-priority patent/SE0500057D0/sv
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of NO20065319L publication Critical patent/NO20065319L/no

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Abstract

Forbindelser med formel (I): preparater som omfatter dem, fremgangsmåter for fremstilling av dem og anvendelse av dem i medisinsk behandling (for eksempel for modulernig av CCR5 reseptoraktivitet i et varmblodig dyr).
NO20065319A 2004-04-23 2006-11-20 Piperidinderivater som modulatorer for kjemokinreseptor CCR5 NO20065319L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE0401057A SE0401057D0 (sv) 2004-04-23 2004-04-23 Chemical Compounds
SE0500057A SE0500057D0 (sv) 2005-01-10 2005-01-10 Chemical compounds
PCT/SE2005/000574 WO2005101989A2 (en) 2004-04-23 2005-04-20 Piperidine derivatives as modulators of chemokine receptor ccr5

Publications (1)

Publication Number Publication Date
NO20065319L true NO20065319L (no) 2007-01-23

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ID=35197429

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Application Number Title Priority Date Filing Date
NO20065319A NO20065319L (no) 2004-04-23 2006-11-20 Piperidinderivater som modulatorer for kjemokinreseptor CCR5

Country Status (16)

Country Link
US (2) US7615555B2 (no)
EP (1) EP1742934A2 (no)
JP (1) JP2007533735A (no)
KR (1) KR20070007345A (no)
AR (1) AR048834A1 (no)
AU (1) AU2005235169B2 (no)
BR (1) BRPI0510126A (no)
CA (1) CA2562417A1 (no)
IL (1) IL178650A0 (no)
MX (1) MXPA06012045A (no)
NO (1) NO20065319L (no)
RU (1) RU2368608C2 (no)
SA (1) SA05260099B1 (no)
TW (1) TW200610761A (no)
UY (1) UY28870A1 (no)
WO (1) WO2005101989A2 (no)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE602007007497D1 (de) * 2006-09-18 2010-08-12 Hoffmann La Roche Octahydropyrroloä3,4-cüpyrrolderivate und ihre verwendung als antivirale mittel
TW200831093A (en) * 2006-12-11 2008-08-01 Astrazeneca Ab Chemical compound
TW200831483A (en) * 2006-12-11 2008-08-01 Astrazeneca Ab Chemical compound
AU2007334519A1 (en) 2006-12-14 2008-06-26 Merck Sharp & Dohme Corp. Acyl bipiperidinyl compounds, compositions containing such compounds and methods of treatment
WO2008101728A1 (de) * 2007-02-23 2008-08-28 K.H.S. Pharma Holding Gmbh Verfahren zur herstellung von azoniaspironortropinestern und von nortropan-3-on verbindungen
US7977358B2 (en) 2007-07-26 2011-07-12 Hoffmann-La Roche Inc. Pyrazol derivatives
NZ599853A (en) 2008-04-11 2012-08-31 Janssen Pharmaceutica Nv Process for the preparation of meso-N-[(3-endo)-8-benzyl-8-azabicyclo[3.2.1]oct-3-yl]acetamide and its derivatives
US8217060B2 (en) 2009-05-15 2012-07-10 Janssen Pharmaceutica, Nv Benzimidazole derivatives useful as TRP M8 receptor modulators
ES2564457T3 (es) 2009-07-24 2016-03-22 Glaxosmithkline Llc Derivados de azabiciclo[3,2,1]octilo para su uso en el tratamiento de VIH
CN102241664B (zh) * 2010-05-13 2014-11-12 上海医药工业研究院 芳烷二胺类衍生物及其作为抗抑郁症药物的应用
JP2013530947A (ja) 2010-05-17 2013-08-01 アレイ バイオファーマ、インコーポレイテッド Gpr119調節薬としてのピペリジニル置換ラクタム
WO2013074641A1 (en) * 2011-11-16 2013-05-23 Array Biopharma Inc. Piperidinyl- substituted cyclic ureas as gpr119 modulators
JP6303250B2 (ja) 2012-12-21 2018-04-04 石原産業株式会社 有害生物防除剤
US9090618B2 (en) 2012-12-27 2015-07-28 Purdue Pharma L.P. Substituted benzimidazole-type piperidine compounds and uses thereof
US10556899B2 (en) * 2018-02-09 2020-02-11 Sci Pharmtech, Inc. Method for preparing Maraviroc

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX9100513A (es) 1990-08-06 1992-04-01 Smith Kline French Lab Compuestos
CA2296314A1 (en) 1997-07-25 1999-02-04 Merck & Co., Inc. Cyclic amine modulators of chemokine receptor activity
IL125658A0 (en) 1997-08-18 1999-04-11 Hoffmann La Roche Ccr-3 receptor antagonists
AR013669A1 (es) * 1997-10-07 2001-01-10 Smithkline Beecham Corp Compuestos y metodos
CN1279668A (zh) 1997-11-18 2001-01-10 帝人株式会社 环胺衍生物及其作为药物的用途
JP2002501898A (ja) 1998-02-02 2002-01-22 メルク エンド カムパニー インコーポレーテッド ケモカイン受容体活性の環状アミン調節剤
US6288083B1 (en) * 1998-09-04 2001-09-11 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
US7217714B1 (en) * 1998-12-23 2007-05-15 Agouron Pharmaceuticals, Inc. CCR5 modulators
EP1013276A1 (en) * 1998-12-23 2000-06-28 Pfizer Inc. Aminoazacycloalkanes as CCR5 modulators
PE20001420A1 (es) * 1998-12-23 2000-12-18 Pfizer Moduladores de ccr5
SE9902987D0 (sv) * 1999-08-24 1999-08-24 Astra Pharma Prod Novel compounds
GB0005642D0 (en) * 2000-03-10 2000-05-03 Astrazeneca Uk Ltd Chemical compounds
GB0011838D0 (en) * 2000-05-17 2000-07-05 Astrazeneca Ab Chemical compounds
JP3693957B2 (ja) * 2000-05-26 2005-09-14 ファイザー・インク 療法において有用なトロパン誘導体
SE0103818D0 (sv) * 2001-11-15 2001-11-15 Astrazeneca Ab Chemical compounds
US6855724B2 (en) * 2002-04-08 2005-02-15 Agouron Pharmaceuticals, Inc. Tropane derivatives useful in therapy
EP1352672A3 (en) * 2002-04-08 2004-01-07 Acrostak Corp. PTCA and/or PTA balloon
CN1744899A (zh) 2002-12-13 2006-03-08 史密丝克莱恩比彻姆公司 作为ccr5拮抗剂的哌啶衍生物
AR042628A1 (es) 2002-12-20 2005-06-29 Astrazeneca Ab Derivados de piperidina como moduladores del receptor ccr5
SE0203820D0 (sv) 2002-12-20 2002-12-20 Astrazeneca Ab chemical compounds
SE0203828D0 (sv) 2002-12-20 2002-12-20 Astrazeneca Ab Chemical compounds
SE0401657D0 (sv) * 2004-06-24 2004-06-24 Astrazeneca Ab Chemical compounds
SE0401656D0 (sv) * 2004-06-24 2004-06-24 Astrazeneca Ab Chemical compounds
TW200831483A (en) * 2006-12-11 2008-08-01 Astrazeneca Ab Chemical compound
TW200831093A (en) * 2006-12-11 2008-08-01 Astrazeneca Ab Chemical compound

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US20070167442A1 (en) 2007-07-19
AU2005235169A1 (en) 2005-11-03
IL178650A0 (en) 2007-02-11
TW200610761A (en) 2006-04-01
SA05260099B1 (ar) 2009-12-22
KR20070007345A (ko) 2007-01-15
RU2368608C2 (ru) 2009-09-27
RU2006138663A (ru) 2008-05-27
MXPA06012045A (es) 2007-01-25
WO2005101989A3 (en) 2006-04-27
WO2005101989A2 (en) 2005-11-03
UY28870A1 (es) 2005-11-30
BRPI0510126A (pt) 2007-06-26
EP1742934A2 (en) 2007-01-17
US7615555B2 (en) 2009-11-10
AU2005235169B2 (en) 2008-09-18
CA2562417A1 (en) 2005-11-03
JP2007533735A (ja) 2007-11-22

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