NO20065195L - Terapeutiske enzymformuleringer og anvendelser derav - Google Patents

Terapeutiske enzymformuleringer og anvendelser derav

Info

Publication number
NO20065195L
NO20065195L NO20065195A NO20065195A NO20065195L NO 20065195 L NO20065195 L NO 20065195L NO 20065195 A NO20065195 A NO 20065195A NO 20065195 A NO20065195 A NO 20065195A NO 20065195 L NO20065195 L NO 20065195L
Authority
NO
Norway
Prior art keywords
applications
enzyme formulations
therapeutic enzyme
enzymes
formulations
Prior art date
Application number
NO20065195A
Other languages
English (en)
Other versions
NO340598B1 (no
Inventor
Lu Shan
Michael Bethune
Chaitan Khosla
Jonathan Gass
Original Assignee
Alvine Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alvine Pharmaceuticals Inc filed Critical Alvine Pharmaceuticals Inc
Publication of NO20065195L publication Critical patent/NO20065195L/no
Publication of NO340598B1 publication Critical patent/NO340598B1/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4813Exopeptidases (3.4.11. to 3.4.19)
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/06Enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482Serine endopeptidases (3.4.21)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/04Antipruritics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dermatology (AREA)
  • Polymers & Plastics (AREA)
  • Microbiology (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Transplantation (AREA)
  • Pulmonology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Farmasøytiske formuleringer av glutenaseenzymer er tilveiebrakt. Enzymene finner spesielt anvendelse i behandlingen av en cøliaki eller dermatitis herpetiformis pasient.
NO20065195A 2004-04-26 2006-11-13 Terapeutiske enzymformuleringer og anvendelser derav NO340598B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US56566804P 2004-04-26 2004-04-26
US10/969,314 US7320788B2 (en) 2002-02-14 2004-10-19 Enzyme treatment of foodstuffs for Celiac Sprue
PCT/US2005/006129 WO2005107786A1 (en) 2004-04-26 2005-02-23 Therapeutic enzyme formulations and uses thereof

Publications (2)

Publication Number Publication Date
NO20065195L true NO20065195L (no) 2007-01-18
NO340598B1 NO340598B1 (no) 2017-05-15

Family

ID=35320040

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20065195A NO340598B1 (no) 2004-04-26 2006-11-13 Terapeutiske enzymformuleringer og anvendelser derav

Country Status (11)

Country Link
US (1) US7320788B2 (no)
EP (1) EP1740197B1 (no)
JP (3) JP2007534752A (no)
AU (1) AU2005239985B2 (no)
CA (1) CA2563505C (no)
DK (1) DK1740197T3 (no)
ES (1) ES2437569T3 (no)
NO (1) NO340598B1 (no)
PL (1) PL1740197T3 (no)
PT (1) PT1740197E (no)
WO (1) WO2005107786A1 (no)

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EP1572127B2 (en) * 2002-02-14 2014-10-29 The Board of Trustees of the Leland Stanford Junior University Enzyme treatment of foodstuffs for celiac sprue
US8143210B2 (en) * 2002-02-14 2012-03-27 The Board Of Trustees Of The Leland Stanford Junior University Enzyme treatment of foodstuffs for celiac sprue
US7605150B2 (en) * 2002-05-14 2009-10-20 The Board Of Trustees Of The Leland Stanford Junior University Drug therapy for Celiac Sprue
US7462688B2 (en) * 2002-05-14 2008-12-09 The Board Of Trustees Of The Leland Stanford Junior University Peptides for diagnostic and therapeutic methods for celiac sprue
US7265093B2 (en) * 2002-05-14 2007-09-04 The Board Of Trustees Of The Leland Stanford Junior University Drug therapy for Celiac Sprue
GB0212885D0 (en) * 2002-06-05 2002-07-17 Isis Innovation Therapeutic epitopes and uses thereof
ES2383595T3 (es) 2002-11-20 2012-06-22 The Board Of Trustees Of The Leland Stanford Junior University Procedimiento de diagnóstico de la celiaquía
US7579313B2 (en) 2003-11-18 2009-08-25 The Board Of Trustees Of The Leland Stanford Junior University Transglutaminase inhibitors and methods of use thereof
US10105437B2 (en) 2004-04-28 2018-10-23 Btg International Limited Epitopes related to coeliac disease
CN104056251B (zh) 2004-04-28 2019-09-17 英国技术集团国际有限公司 与腹部疾病有关的表位
IL161886A0 (en) * 2004-05-09 2005-11-20 Technion Res & Dev Foundation Development of inducers of udp-n-acetyl-alphad-galactosamine: polypeptide n-acetylgalactosami-nyltransferase 3(ppgantase
WO2006097949A1 (en) * 2005-03-16 2006-09-21 Actial Farmacêutica, Lda. Mixture of at least 6 species of lactic acid bacteria and/or bifidobacteria in the manufacture of sourdough
WO2007044906A2 (en) * 2005-10-11 2007-04-19 Alvine Pharmaceuticals, Inc. Compositions and methods for enhanced gastrointestinal stability of oligopeptides and polypeptides
BRPI0617317A2 (pt) 2005-10-11 2011-07-19 Mofin S R L método para preparação de composição incluindo pelo menos uma cultura de bolor ou esporo isenta de glúten, composição, método para preparação de produto laticìnio de marmoreamento azul
WO2008115428A2 (en) * 2007-03-16 2008-09-25 The Board Of Trustees Of The Leland Stanford Junior University A scaleable manufacturing process for cysteine endoprotease b, isoform 2
EP2136833B1 (en) * 2007-03-16 2019-05-01 The Board of Trustees of the Leland Stanford Junior University Combination enzyme therapy for digestion of dietary gluten
US20100322912A1 (en) * 2007-12-10 2010-12-23 Chaitan Khosla Combination Enzyme Therapy for Gastric Digestion of Dietary Gluten in Celiac Sprue Patients
ES2343499B1 (es) * 2007-12-24 2011-06-10 Consejo Superior De Investigaciones Cientificas Microorganismos para mejorar el estado de salud de individuos con desordenes relacionados con la ingesta de gluten.
DK2321640T3 (en) * 2008-08-21 2017-02-27 Immunogenics Llc FORMULATION FOR ORAL ADMINISTRATION OF PROTEINS
WO2010042203A1 (en) * 2008-10-10 2010-04-15 Alvine Pharmaceuticals, Inc. Dosage forms that facilitate rapid activation of zymogen
CA3042826A1 (en) 2008-11-30 2010-06-03 Immusant, Inc. Compositions and methods for treatment of celiac disease
AU2010205890B2 (en) * 2009-01-15 2015-01-15 Glutagen Pty Ltd Compositions for the treatment of gluten intolerance and uses thereof
DE102009045268A1 (de) 2009-10-01 2011-04-07 Charité - Universitätsmedizin Berlin Neue Marker für die Diagnose von Zöliakie
WO2011044365A1 (en) 2009-10-07 2011-04-14 Trustees Of Boston University Rothia species glutamine endopeptidases and use thereof
CN102858795A (zh) 2010-02-02 2013-01-02 天野酶制品美国有限公司 蛋白酶针对谷蛋白不耐受的用途
EA031179B1 (ru) * 2010-03-12 2018-11-30 Компани Жервэ Данон Молочнокислые бактерии, применяемые при чревной болезни
WO2012006384A2 (en) 2010-07-07 2012-01-12 Trustees Of Boston University Rothia species gluten-degrading enzymes and uses thereof
CA3009238C (en) * 2011-01-20 2020-10-27 Cyrex Laboratories, Llc Methods and apparatus for detection of gluten sensitivity, and its differentiation from celiac disease
US9267128B2 (en) 2011-03-30 2016-02-23 Alvine Pharmaceuticals, Inc. Proteases for degrading gluten
WO2013016427A1 (en) 2011-07-25 2013-01-31 Alvine Pharmaceuticals, Inc. Methods and pharmaceutical compositions for treating celiac disease and gluten intolerance
HUE037870T2 (hu) 2011-08-10 2018-09-28 Univ Washington Through Its Center For Commercialization Készítmények és módszerek lisztérzékenység kezelésére
US20140219982A1 (en) * 2011-09-29 2014-08-07 Amano Enzyme Inc. Exogenous opioid peptide-degrading enzyme
AU2012348782B2 (en) * 2011-12-06 2017-10-26 Fondazione Istituto Insubrico Di Ricerca Per La Vita New proteases able to hydrolyze gluten peptides and proteins at acidic pH, from the Actinomycete Actinoallomurus
WO2014011662A2 (en) * 2012-07-09 2014-01-16 Alvine Pharmaceuticals, Inc. Acid stable prolyl endopeptidases for degrading gluten
ITRM20120468A1 (it) * 2012-10-02 2014-04-03 Uni Degli Studi Di Foggia Metodo per la detossificazione delle proteine del glutine dalla granella dei cereali
US9005610B2 (en) 2012-11-21 2015-04-14 Nepetx, Llc Treatment of gluten intolerance and related conditions
WO2014116871A1 (en) 2013-01-23 2014-07-31 Alvine Pharmaceuticals, Inc. Methods and pharmaceutical compositions for treating celiac disease and gluten intolerance
WO2015023728A1 (en) 2013-08-14 2015-02-19 University Of Washington Through Its Center For Commercialization Compositions and methods for treating celiac sprue disease
CA2923822A1 (en) 2013-09-10 2015-03-19 Immusant, Inc. Dosage of a gluten peptide composition
EP2883458A1 (en) * 2013-12-11 2015-06-17 DSM IP Assets B.V. Medicament and method for treating innate immune response diseases
CN106488772B (zh) * 2014-05-07 2020-11-27 内米西斯有限公司 用于乳糜泄的口服酶疗法的甲基丙烯酸透明质酸衍生物的水凝胶
WO2015192211A1 (en) * 2014-06-16 2015-12-23 Nepetx, Llc Compositions and methods for treating gluten intolerance and disorders arising therefrom
WO2016054038A1 (en) 2014-09-29 2016-04-07 Immusant, Inc. Use of hla genetic status to assess or select treatment of celiac disease
FR3034307B1 (fr) 2015-04-03 2021-10-22 Univ Grenoble 1 Reacteur intestinal implantable
US10793846B2 (en) 2015-06-08 2020-10-06 University Of Washington Compositions and methods for treating celiac sprue disease
JP2019504011A (ja) 2015-12-16 2019-02-14 ネプエトゥクス,エルエルシー グルテン不耐症およびそれにより発生する障害を治療するための組成物および方法
US20190307860A1 (en) 2016-11-23 2019-10-10 Immunogenics Llc Latiglutenase (alv003) for use in the treatment of symptomatic celiac disease, gluten intolerance or gluten sensitivity
WO2020087017A1 (en) * 2018-10-26 2020-04-30 The Regents Of The University Of California Use of proteolytic enzymes to enhance protein bioavailability
KR102184812B1 (ko) * 2018-12-13 2020-11-30 대한민국 새찰쌀보리 추출물을 포함하는 골다공증 예방 또는 치료용 조성물
WO2020205871A1 (en) * 2019-04-02 2020-10-08 Muhammed Majeed Method and composition for therapeutic management of gluten intolerance
IT201900012942A1 (it) 2019-07-25 2021-01-25 Nemysis Ltd Metodo per la produzione di una composizione enzimatica comprendente una endopeptidasi ricombinante
CN114174519A (zh) 2019-07-25 2022-03-11 内米西斯有限公司 用于生产包含重组内肽酶的酶组合物的方法
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Also Published As

Publication number Publication date
AU2005239985A1 (en) 2005-11-17
CA2563505C (en) 2020-09-08
EP1740197A4 (en) 2009-09-16
AU2005239985B2 (en) 2010-08-12
PT1740197E (pt) 2013-12-02
NO340598B1 (no) 2017-05-15
US7320788B2 (en) 2008-01-22
CA2563505A1 (en) 2005-11-17
JP2007534752A (ja) 2007-11-29
PL1740197T3 (pl) 2014-03-31
DK1740197T3 (da) 2013-11-11
WO2005107786A1 (en) 2005-11-17
JP2012092125A (ja) 2012-05-17
ES2437569T3 (es) 2014-01-13
EP1740197A1 (en) 2007-01-10
US20050249719A1 (en) 2005-11-10
JP2015063554A (ja) 2015-04-09
EP1740197B1 (en) 2013-10-16

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Legal Events

Date Code Title Description
CHAD Change of the owner's name or address (par. 44 patent law, par. patentforskriften)

Owner name: THE BOARD OF TRUSTEES OF THE LELAND STANFORD, US

MM1K Lapsed by not paying the annual fees