NO20065156L - Hittil ukjente forbindelser for behandling av hjertearytmi og bruksmetoder - Google Patents

Hittil ukjente forbindelser for behandling av hjertearytmi og bruksmetoder

Info

Publication number
NO20065156L
NO20065156L NO20065156A NO20065156A NO20065156L NO 20065156 L NO20065156 L NO 20065156L NO 20065156 A NO20065156 A NO 20065156A NO 20065156 A NO20065156 A NO 20065156A NO 20065156 L NO20065156 L NO 20065156L
Authority
NO
Norway
Prior art keywords
treatment
methods
cardiac arrhythmias
hitherto unknown
unknown compounds
Prior art date
Application number
NO20065156A
Other languages
English (en)
Inventor
Pascal Druzgala
Original Assignee
Aryx Therapeutics
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aryx Therapeutics filed Critical Aryx Therapeutics
Publication of NO20065156L publication Critical patent/NO20065156L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/80—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Den foreliggende oppfinnelsen skaffer til veie forbindelser med formel II eller et farmasøytisk akseptabelt salt derav for behandling av hjertearytmi og fremgangsmåter for bruk, hvori Rier HellerCi-Cioalkyl; R2 er H eller eventuell substituert Ci-Cio alkyl, heteroalkyl, sykloalkyl eller heterosykloalkyl; n= 0 til 4 p= 0 eller 1 R3 og R4 er uavhengig H eller C1-C4 alkyl
NO20065156A 2004-04-09 2006-11-09 Hittil ukjente forbindelser for behandling av hjertearytmi og bruksmetoder NO20065156L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US56091704P 2004-04-09 2004-04-09
PCT/US2005/012138 WO2005099684A1 (en) 2004-04-09 2005-04-08 Benzofuranyl derivatives useful for the treatment of cardiac arrhythmia

Publications (1)

Publication Number Publication Date
NO20065156L true NO20065156L (no) 2006-11-09

Family

ID=34965215

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20065156A NO20065156L (no) 2004-04-09 2006-11-09 Hittil ukjente forbindelser for behandling av hjertearytmi og bruksmetoder

Country Status (14)

Country Link
US (3) US7105568B2 (no)
EP (1) EP1732537A1 (no)
JP (1) JP2007532576A (no)
KR (1) KR20070001259A (no)
CN (1) CN1950080A (no)
AU (1) AU2005232701A1 (no)
BR (1) BRPI0509740A (no)
CA (1) CA2560336A1 (no)
IL (1) IL178127A0 (no)
MX (1) MXPA06011647A (no)
NO (1) NO20065156L (no)
RU (1) RU2373199C2 (no)
WO (1) WO2005099684A1 (no)
ZA (1) ZA200607666B (no)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2005232701A1 (en) * 2004-04-09 2005-10-27 Aryx Therapeutics Benzofuranyl derivatives useful for the treatment of cardiac arrhytmia
RU2446143C2 (ru) * 2010-05-19 2012-03-27 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Ярославский государственный технический университет" (ЯГТУ) Способ получения эфиров замещенных 5,6-дицианобензофуран-2-карбоновых кислот
CN108396016B (zh) * 2018-02-05 2021-05-25 中国科学院南海海洋研究所 一种酯酶phe21及其编码基因和在手性乙酸仲丁酯制备中的应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2550091B1 (fr) * 1983-08-02 1986-05-23 Sanofi Sa Composition pharmaceutique ou veterinaire destinee a combattre des troubles ischemiques cardiaques contenant un derive du benzofuranne
US5175187A (en) * 1989-03-06 1992-12-29 Soorianarain Baligadoo Synergistic compositions for the treatment of coronary insufficiency and methods of use thereof
US5364880A (en) * 1993-06-16 1994-11-15 Advanced Therapies, Inc. Compound for treatment of cardiac arrhythmia, synthesis, and methods of use
US6309823B1 (en) * 1993-10-26 2001-10-30 Affymetrix, Inc. Arrays of nucleic acid probes for analyzing biotransformation genes and methods of using the same
US6121278A (en) * 1997-09-03 2000-09-19 Guilford Pharmaceuticals, Inc. Di-n-heterocyclic compounds, methods, and compositions for inhibiting parp activity
ATE369351T1 (de) * 1999-10-15 2007-08-15 Aryx Therapeutics Enantiomere verbindungen zur behandlung von herzrythmusstörungen und verfahren zu ihrer anwendung
EP1451169A1 (en) * 2001-12-10 2004-09-01 ARYx Therapeutics Novel compounds for the treatment of cardiac arrhythmia, synthesis, and methods of use
US7015568B2 (en) * 2003-08-21 2006-03-21 Texas Instruments Incorporated System for ultraviolet atmospheric seed layer remediation
AU2005232701A1 (en) * 2004-04-09 2005-10-27 Aryx Therapeutics Benzofuranyl derivatives useful for the treatment of cardiac arrhytmia

Also Published As

Publication number Publication date
US7351842B2 (en) 2008-04-01
CN1950080A (zh) 2007-04-18
BRPI0509740A (pt) 2007-09-25
ZA200607666B (en) 2008-03-26
RU2373199C2 (ru) 2009-11-20
RU2006139649A (ru) 2008-05-20
AU2005232701A1 (en) 2005-10-27
US20080114059A1 (en) 2008-05-15
EP1732537A1 (en) 2006-12-20
US20050228045A1 (en) 2005-10-13
KR20070001259A (ko) 2007-01-03
US7105568B2 (en) 2006-09-12
JP2007532576A (ja) 2007-11-15
MXPA06011647A (es) 2007-04-13
WO2005099684A1 (en) 2005-10-27
IL178127A0 (en) 2006-12-31
US20060276535A1 (en) 2006-12-07
CA2560336A1 (en) 2005-10-27

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Legal Events

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FC2A Withdrawal, rejection or dismissal of laid open patent application