NO20064351L - Caspaseinhibitorer og anvendelser derav - Google Patents

Caspaseinhibitorer og anvendelser derav

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Publication number
NO20064351L
NO20064351L NO20064351A NO20064351A NO20064351L NO 20064351 L NO20064351 L NO 20064351L NO 20064351 A NO20064351 A NO 20064351A NO 20064351 A NO20064351 A NO 20064351A NO 20064351 L NO20064351 L NO 20064351L
Authority
NO
Norway
Prior art keywords
caspase inhibitors
compounds
formula
present
provides
Prior art date
Application number
NO20064351A
Other languages
English (en)
Norwegian (no)
Inventor
John Studley
Jean-Damien Charrier
Michael Mortimore
Steven Durrant
Michael O'donnell
Alistair Rutherford
Sharn Ramaya
Martin Trudeau
Adam Looker
Original Assignee
Vertex Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34923260&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20064351(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Vertex Pharma filed Critical Vertex Pharma
Publication of NO20064351L publication Critical patent/NO20064351L/no

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    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0202—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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NO20064351A 2004-02-27 2006-09-26 Caspaseinhibitorer og anvendelser derav NO20064351L (no)

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PE20011350A1 (es) 2000-05-19 2002-01-15 Vertex Pharma PROFARMACO DE UN INHIBIDOR DE ENZIMA CONVERTIDORA DE INTERLEUCINA-1ß (ICE)
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US20060128696A1 (en) * 2004-05-15 2006-06-15 Annamaria Vezzani Treating seizures using ice inhibitors
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WO2017079566A1 (en) 2015-11-05 2017-05-11 Conatus Pharmaceuticals, Inc. Caspase inhibitors for use in the treatment of liver cancer
BR112018013558A2 (pt) 2015-12-31 2018-12-04 Conatus Pharmaceuticals Inc método de tratamento de uma doença hepática em um indivíduo, método de uso de um inibidor de caspase, método para diminuir ou sustentar uma classificação meld ou seus componentes, método para tratar, diminuir ou sustentar uma classificação meld ou seus componentes, método para tratar, diminuir ou sustentar uma classificação de child-pugh ou seus componentes, composição farmacêutica que compreende um inibidor de caspase, kit, método de tratamento, método de tratamento de cirrose hepática e prevenção de uma classificação meld elevada, método de tratamento de cirrose hepática e prevenção de uma classificação de child-pugh elevada
CN105853408B (zh) * 2016-04-15 2018-12-04 浙江大学 苯酰胺衍生物在制备Caspase-1抑制剂中的应用
RU2019113150A (ru) 2016-10-05 2020-11-06 Новартис Аг Комбинация композиций, содержащих агонисты fxr, предназначенная для лечения или предупреждения фиброзирующего, цирротического заболевания или нарушения
WO2022123062A1 (en) 2020-12-11 2022-06-16 INSERM (Institut National de la Santé et de la Recherche Médicale) Blocking caspase and/or fasl for preventing fatal outcome in covid-19 patients
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AU2005219861B2 (en) 2011-08-11
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JP2007525503A (ja) 2007-09-06
AR047981A1 (es) 2006-03-15
ZA200607634B (en) 2008-01-08
TW200540152A (en) 2005-12-16
CA2557645C (en) 2013-09-24
JP2014140385A (ja) 2014-08-07
KR20060129069A (ko) 2006-12-14
CA2557645A1 (en) 2005-09-15
WO2005085236A2 (en) 2005-09-15
CN102161656B (zh) 2013-02-20
TW201217332A (en) 2012-05-01
EP1718639A2 (de) 2006-11-08
RU2006134258A (ru) 2008-04-10
CN102161656A (zh) 2011-08-24
US20100105914A1 (en) 2010-04-29
US20050233979A1 (en) 2005-10-20
EP2270004A1 (de) 2011-01-05
WO2005085236A3 (en) 2005-10-20
US7652153B2 (en) 2010-01-26
TWI362381B (en) 2012-04-21
NZ549665A (en) 2010-09-30
JP2011144203A (ja) 2011-07-28
HK1099757A1 (en) 2007-08-24
NO20064344L (no) 2006-10-19
IL177709A0 (en) 2006-12-31
RU2382780C2 (ru) 2010-02-27

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