NO20063772L - Sammensetninger og fremgangsmater vedrorende dyrking av neural stamceller med benmarg fra stromaceller - Google Patents

Sammensetninger og fremgangsmater vedrorende dyrking av neural stamceller med benmarg fra stromaceller

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Publication number
NO20063772L
NO20063772L NO20063772A NO20063772A NO20063772L NO 20063772 L NO20063772 L NO 20063772L NO 20063772 A NO20063772 A NO 20063772A NO 20063772 A NO20063772 A NO 20063772A NO 20063772 L NO20063772 L NO 20063772L
Authority
NO
Norway
Prior art keywords
methods
neural stem
compositions
stem cells
bone marrow
Prior art date
Application number
NO20063772A
Other languages
English (en)
Inventor
Smita Savant-Bhonsale
Padmavathy Vanguri
Original Assignee
Theradigm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Theradigm Inc filed Critical Theradigm Inc
Publication of NO20063772L publication Critical patent/NO20063772L/no

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0618Cells of the nervous system
    • C12N5/0623Stem cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662Stem cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/11Epidermal growth factor [EGF]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/115Basic fibroblast growth factor (bFGF, FGF-2)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20Cytokines; Chemokines
    • C12N2501/23Interleukins [IL]
    • C12N2501/235Leukemia inhibitory factor [LIF]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00Coculture with; Conditioned medium produced by
    • C12N2502/13Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
    • C12N2502/1352Mesenchymal stem cells
    • C12N2502/1358Bone marrow mesenchymal stem cells (BM-MSC)

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Developmental Biology & Embryology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

Foreliggende oppfinnelse omfatter metoder og sammensetninger for å forøke veksten av neuralstamceller. Metoder for modulering av MHC-molekylekspresjon på en neural stamcelle (NSC) er også inkludert i oppfinnelsen.
NO20063772A 2004-02-06 2006-08-23 Sammensetninger og fremgangsmater vedrorende dyrking av neural stamceller med benmarg fra stromaceller NO20063772L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US54258104P 2004-02-06 2004-02-06
US63352104P 2004-12-06 2004-12-06
PCT/US2005/002895 WO2005076845A2 (en) 2004-02-06 2005-02-01 Compositions and methods relating to culturing neural stem cells with bone marrow stromal cells

Publications (1)

Publication Number Publication Date
NO20063772L true NO20063772L (no) 2006-10-03

Family

ID=34864500

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20063772A NO20063772L (no) 2004-02-06 2006-08-23 Sammensetninger og fremgangsmater vedrorende dyrking av neural stamceller med benmarg fra stromaceller

Country Status (12)

Country Link
US (1) US20050176141A1 (no)
EP (1) EP1718733A4 (no)
JP (1) JP2007520233A (no)
KR (1) KR20070001171A (no)
AU (1) AU2005213326A1 (no)
BR (1) BRPI0507429A (no)
CA (1) CA2555376A1 (no)
CR (1) CR8547A (no)
MX (1) MXPA06008932A (no)
NO (1) NO20063772L (no)
RU (1) RU2006132068A (no)
WO (1) WO2005076845A2 (no)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
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WO2007113387A1 (en) * 2006-03-31 2007-10-11 Jozef Bizik Method and device for treating or selecting cells
EP2054506A1 (en) * 2006-08-15 2009-05-06 Agency for Science, Technology and Research Mesenchymal stem cell conditioned medium
KR100980849B1 (ko) * 2007-04-25 2010-09-10 가톨릭대학교 산학협력단 인터루킨(il)-10을 포함하는 조혈모세포의 자가 재생산을촉진하는 조성물
EP2155860B1 (en) * 2007-05-03 2014-08-27 The Brigham and Women's Hospital, Inc. Multipotent stem cells and uses thereof
US8318485B2 (en) * 2008-02-25 2012-11-27 Natalie Gavrilova Stem cell therapy for the treatment of diabetic retinopathy and diabetic optic neuropathy
KR101077042B1 (ko) * 2008-03-28 2011-10-26 경희대학교 산학협력단 중배엽 줄기세포의 증식을 촉진하기 위한 cd45+ 세포 또는 cd45+ 세포 배양액의 용도
CN102325878A (zh) * 2008-12-23 2012-01-18 斯特姆塞尔思加利福尼亚有限公司 少突胶质前体细胞的靶向细胞群及制备与使用方法
CN101735980B (zh) * 2010-02-11 2011-07-27 中国人民解放军总医院 体外培养骨髓间充质干细胞的完全培养基
US9428730B2 (en) 2012-02-29 2016-08-30 Mead Johnson Nutrition Company Coatings and culture media for promoting neurogenesis in adipose tissue derived stem cells
CN104324053B (zh) * 2014-09-28 2018-09-11 严玉霖 一种快速愈合犬创伤组织的犬干细胞分泌因子修复液
CN105420193B (zh) * 2015-12-07 2019-04-09 中国科学院广州生物医药与健康研究院 分化培养基及其在制备神经干细胞中的用途
WO2020153687A1 (ko) * 2019-01-22 2020-07-30 고려대학교 산학협력단 직접 세포전환을 기반으로한 신경줄기세포의 성상교세포로의 분화방법

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5750376A (en) * 1991-07-08 1998-05-12 Neurospheres Holdings Ltd. In vitro growth and proliferation of genetically modified multipotent neural stem cells and their progeny
US5849553A (en) * 1992-07-27 1998-12-15 California Institute Of Technology Mammalian multipotent neural stem cells
US6528245B2 (en) * 1998-05-07 2003-03-04 University Of South Florida Bone marrow cells as a source of neurons for brain and spinal cord repair
JP4526186B2 (ja) * 1998-06-08 2010-08-18 オシリス セラピューティクス,インコーポレイテッド 造血幹細胞を試験管内で維持する方法と組成物
US5958767A (en) * 1998-08-14 1999-09-28 The Children's Medical Center Corp. Engraftable human neural stem cells
US6372494B1 (en) * 1999-05-14 2002-04-16 Advanced Tissue Sciences, Inc. Methods of making conditioned cell culture medium compositions
EP1335972A2 (en) * 2000-11-22 2003-08-20 Geron Corporation Tolerizing allografts of pluripotent stem cells
US20030082153A1 (en) * 2001-10-22 2003-05-01 The Government Of The United States Of America Stem cells that transform to beating cardiomyocytes
US20060252150A1 (en) * 2002-11-08 2006-11-09 Linzhao Cheng Human embryonic stem cell cultures, and compositions and methods for growing same

Also Published As

Publication number Publication date
WO2005076845A2 (en) 2005-08-25
AU2005213326A1 (en) 2005-08-25
CA2555376A1 (en) 2005-08-25
JP2007520233A (ja) 2007-07-26
RU2006132068A (ru) 2008-03-20
WO2005076845A3 (en) 2005-10-06
BRPI0507429A (pt) 2007-06-26
EP1718733A2 (en) 2006-11-08
US20050176141A1 (en) 2005-08-11
EP1718733A4 (en) 2007-02-07
CR8547A (es) 2007-09-07
KR20070001171A (ko) 2007-01-03
MXPA06008932A (es) 2007-01-26

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