NO20063080L - Azepinoindolderivater som farmasoytiske midler - Google Patents
Azepinoindolderivater som farmasoytiske midlerInfo
- Publication number
- NO20063080L NO20063080L NO20063080A NO20063080A NO20063080L NO 20063080 L NO20063080 L NO 20063080L NO 20063080 A NO20063080 A NO 20063080A NO 20063080 A NO20063080 A NO 20063080A NO 20063080 L NO20063080 L NO 20063080L
- Authority
- NO
- Norway
- Prior art keywords
- pharmaceutical agents
- modulating
- compounds
- azepinoindole derivatives
- methods
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Child & Adolescent Psychology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Emergency Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/895,431 US7595311B2 (en) | 2002-05-24 | 2003-12-02 | Azepinoindole derivatives as pharmaceutical agents |
PCT/US2004/040352 WO2005056554A2 (en) | 2003-12-02 | 2004-12-01 | Azepinoindole derivatives as pharmaceutical agents |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20063080L true NO20063080L (no) | 2006-08-23 |
Family
ID=34679499
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20063080A NO20063080L (no) | 2003-12-02 | 2006-07-03 | Azepinoindolderivater som farmasoytiske midler |
Country Status (16)
Country | Link |
---|---|
US (2) | US7595311B2 (ru) |
EP (1) | EP1692136A2 (ru) |
JP (2) | JP2007513168A (ru) |
KR (2) | KR20120091269A (ru) |
CN (2) | CN102358741A (ru) |
AU (1) | AU2004297198B2 (ru) |
BR (1) | BRPI0417260A (ru) |
CA (1) | CA2555279C (ru) |
CR (1) | CR8497A (ru) |
IL (1) | IL176014A0 (ru) |
NO (1) | NO20063080L (ru) |
NZ (1) | NZ548179A (ru) |
RU (1) | RU2423363C2 (ru) |
UA (1) | UA86957C2 (ru) |
WO (1) | WO2005056554A2 (ru) |
ZA (1) | ZA200604352B (ru) |
Families Citing this family (68)
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DE10252667A1 (de) | 2002-11-11 | 2004-05-27 | Grünenthal GmbH | Spirocyclische Cyclohexan-Derivate |
AU2004259009A1 (en) * | 2003-07-23 | 2005-02-03 | Exelixis, Inc. | Azepine derivatives as pharmaceutical agents |
US7767689B2 (en) * | 2004-03-15 | 2010-08-03 | Ptc Therapeutics, Inc. | Carboline derivatives useful in the treatment of cancer |
JP4857452B2 (ja) | 2004-03-15 | 2012-01-18 | ピーティーシー セラピューティクス,インコーポレーテッド | 血管新生の抑制に有用なカルボリン誘導体 |
US8076353B2 (en) | 2004-03-15 | 2011-12-13 | Ptc Therapeutics, Inc. | Inhibition of VEGF translation |
US8076352B2 (en) | 2004-03-15 | 2011-12-13 | Ptc Therapeutics, Inc. | Administration of carboline derivatives useful in the treatment of cancer and other diseases |
DE102005016460A1 (de) * | 2005-04-11 | 2006-10-19 | Grünenthal GmbH | Spriocyclische Cyclohexanderivate zur Behandlung von Substanzabhängigkeit |
US7943576B2 (en) * | 2005-11-30 | 2011-05-17 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Methods of using enterostatin as inhibitor of angiogenesis |
EP1963331A1 (en) * | 2005-12-15 | 2008-09-03 | Exelixis, Inc. | Azepinoindole derivatives as pharmaceutical agents |
CA2627630A1 (en) * | 2005-12-20 | 2007-06-28 | Novartis Ag | Nicotinic acid derivatives as modulators of metabotropic glutamate receptors |
EP2086970B1 (en) * | 2006-08-24 | 2014-02-26 | Novartis AG | 2-(pyrazin-2-yl)-thiazole and 2-(1h pyrazol-3-yl)-thiazole derivatives as well as related compounds as stearoyl-coa desaturase (scd) inhibitors for the treatment of metabolic, cardiovascular and other disorders |
JP5351025B2 (ja) * | 2006-09-22 | 2013-11-27 | ノバルティス アーゲー | ヘテロ環式有機化合物 |
BRPI0720452A2 (pt) * | 2006-12-20 | 2014-01-14 | Novartis Ag | Compostos orgânicos |
DE102007009235A1 (de) * | 2007-02-22 | 2008-09-18 | Grünenthal GmbH | Spirocyclische Cyclohexan-Derivate |
US20080300235A1 (en) * | 2007-06-01 | 2008-12-04 | Wyeth | FXR Agonists for Reducing LOX-1 Expression |
US20080299118A1 (en) * | 2007-06-01 | 2008-12-04 | Wyeth | FXR Agonists for the Treatment of Malignancies |
EP2025674A1 (de) | 2007-08-15 | 2009-02-18 | sanofi-aventis | Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
US20090163474A1 (en) * | 2007-10-19 | 2009-06-25 | Wyeth | FXR Agonists for the Treatment of Nonalcoholic Fatty Liver and Cholesterol Gallstone Diseases |
US20090215748A1 (en) * | 2007-12-20 | 2009-08-27 | Wyeth | FXR agonists for treating vitamin D associated diseases |
JP5501251B2 (ja) | 2008-01-11 | 2014-05-21 | アルバニー モレキュラー リサーチ, インコーポレイテッド | Mch拮抗薬としての(1−アジノン)置換ピリドインドール類 |
MX2010010337A (es) | 2008-03-27 | 2010-10-07 | Gruenenthal Gmbh | Derivados de espiro(5.5)undecano. |
DK2260042T3 (da) * | 2008-03-27 | 2011-10-31 | Gruenenthal Gmbh | Substituerede spirocykliske cyklohexan-derivater |
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RU2514192C2 (ru) * | 2008-03-27 | 2014-04-27 | Грюненталь Гмбх | Гидроксиметилциклогексиламины |
ES2621407T3 (es) * | 2008-03-27 | 2017-07-04 | Grünenthal GmbH | Ciclohexildiaminas sustituidas |
EP2334681A1 (en) * | 2008-09-26 | 2011-06-22 | Wyeth LLC | 1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxylate nuclear receptor inhibitors |
EP2942350A1 (en) | 2008-10-17 | 2015-11-11 | Xenon Pharmaceuticals Inc. | Spiro-oxindole compounds and their use as therapeutic agents |
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WO2011107494A1 (de) | 2010-03-03 | 2011-09-09 | Sanofi | Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung |
WO2011157827A1 (de) | 2010-06-18 | 2011-12-22 | Sanofi | Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen |
US8993765B2 (en) | 2010-12-21 | 2015-03-31 | Albany Molecular Research, Inc. | Tetrahydro-azacarboline MCH-1 antagonists, methods of making, and uses thereof |
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US10092574B2 (en) | 2012-09-26 | 2018-10-09 | Valorisation-Recherche, Limited Partnership | Inhibitors of polynucleotide repeat-associated RNA foci and uses thereof |
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US10077268B2 (en) | 2014-03-13 | 2018-09-18 | Salk Institute For Biological Studies | FXR agonists and methods for making and using |
US10301268B2 (en) | 2014-03-13 | 2019-05-28 | The Salk Institute For Biological Studies | Analogs of fexaramine and methods of making and using |
CN111662297A (zh) * | 2014-11-21 | 2020-09-15 | 阿卡纳治疗学有限公司 | 用于治疗疾病的稠合双环化合物 |
CN112655433B (zh) * | 2014-12-26 | 2023-01-06 | 富士胶片株式会社 | 农业大棚 |
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CH445512A (de) * | 1964-12-03 | 1967-10-31 | Geigy Ag J R | Verfahren zur Herstellung von neuen Indolderivaten |
GR35044B (el) | 1966-05-10 | 1968-07-31 | The Upjohn Company | Μεθοδος παρασκευης οργανικων ενωσεων. |
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FR2455039A1 (fr) | 1979-04-26 | 1980-11-21 | Synthelabo | Pyrimido et imidazo-pyrido-indole-diones et leur application en therapeutique |
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LU85894A1 (fr) * | 1985-05-10 | 1986-12-05 | Omnichem Sa | Derives de 1,2,3,4,5,6-hexahydro-azepino (4,5-b) indole leur preparation,composes intermediaires,et leur application en therapeutique |
HU198012B (en) | 1987-07-03 | 1989-07-28 | Richter Gedeon Vegyeszet | Process for producing cyclic amino-acid derivatives and pharmaceutical compositions containing them |
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ATE229954T1 (de) | 1998-06-12 | 2003-01-15 | Sod Conseils Rech Applic | Betacarbolinverbindungen |
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US7030109B2 (en) | 1999-07-19 | 2006-04-18 | Pharmacia & Upjohn Company | 1,2,3,4,5,6-Hexahydroazepino[4,5-b]indoles containing arylsulfones at the 9-position |
MY122278A (en) | 1999-07-19 | 2006-04-29 | Upjohn Co | 1,2,3,4,5,6-hexahydroazepino[4,5-b]indoles containing arylsulfones at the 9-position |
FR2799757B1 (fr) * | 1999-10-15 | 2001-12-14 | Adir | Nouveaux derives polycycliques azaindoliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
US6586421B2 (en) * | 2000-09-20 | 2003-07-01 | Pharmacia & Upjohn Company | Substituted azepino[4,5b]indoline derivatives |
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TWI329111B (en) * | 2002-05-24 | 2010-08-21 | X Ceptor Therapeutics Inc | Azepinoindole and pyridoindole derivatives as pharmaceutical agents |
AU2004259009A1 (en) * | 2003-07-23 | 2005-02-03 | Exelixis, Inc. | Azepine derivatives as pharmaceutical agents |
-
2003
- 2003-12-02 US US10/895,431 patent/US7595311B2/en not_active Expired - Lifetime
-
2004
- 2004-12-01 JP JP2006542742A patent/JP2007513168A/ja active Pending
- 2004-12-01 KR KR1020127014076A patent/KR20120091269A/ko active IP Right Grant
- 2004-12-01 EP EP04812795A patent/EP1692136A2/en not_active Withdrawn
- 2004-12-01 UA UAA200607302A patent/UA86957C2/ru unknown
- 2004-12-01 NZ NZ548179A patent/NZ548179A/en not_active IP Right Cessation
- 2004-12-01 RU RU2006123424/04A patent/RU2423363C2/ru active
- 2004-12-01 BR BRPI0417260-4A patent/BRPI0417260A/pt not_active IP Right Cessation
- 2004-12-01 CN CN2011102439838A patent/CN102358741A/zh active Pending
- 2004-12-01 WO PCT/US2004/040352 patent/WO2005056554A2/en active Application Filing
- 2004-12-01 AU AU2004297198A patent/AU2004297198B2/en not_active Ceased
- 2004-12-01 CN CNA200480041235XA patent/CN1914207A/zh active Pending
- 2004-12-01 CA CA2555279A patent/CA2555279C/en active Active
-
2006
- 2006-05-29 ZA ZA200604352A patent/ZA200604352B/xx unknown
- 2006-05-30 IL IL176014A patent/IL176014A0/en unknown
- 2006-06-28 CR CR8497A patent/CR8497A/es not_active Application Discontinuation
- 2006-06-30 KR KR1020067013217A patent/KR101270072B1/ko active IP Right Grant
- 2006-07-03 NO NO20063080A patent/NO20063080L/no not_active Application Discontinuation
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2009
- 2009-08-04 US US12/535,453 patent/US8524704B2/en not_active Expired - Lifetime
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2011
- 2011-06-10 JP JP2011130688A patent/JP2011207907A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
US20100173824A1 (en) | 2010-07-08 |
RU2423363C2 (ru) | 2011-07-10 |
CA2555279A1 (en) | 2005-06-23 |
CA2555279C (en) | 2012-10-23 |
WO2005056554A2 (en) | 2005-06-23 |
AU2004297198A1 (en) | 2005-06-23 |
EP1692136A2 (en) | 2006-08-23 |
US20050054634A1 (en) | 2005-03-10 |
KR20060124662A (ko) | 2006-12-05 |
JP2011207907A (ja) | 2011-10-20 |
WO2005056554A3 (en) | 2005-08-18 |
AU2004297198B2 (en) | 2012-02-09 |
KR101270072B1 (ko) | 2013-05-31 |
BRPI0417260A (pt) | 2007-03-06 |
US7595311B2 (en) | 2009-09-29 |
CN102358741A (zh) | 2012-02-22 |
KR20120091269A (ko) | 2012-08-17 |
IL176014A0 (en) | 2006-10-05 |
CN1914207A (zh) | 2007-02-14 |
RU2006123424A (ru) | 2008-01-10 |
CR8497A (es) | 2006-11-17 |
ZA200604352B (en) | 2008-12-31 |
JP2007513168A (ja) | 2007-05-24 |
UA86957C2 (ru) | 2009-06-10 |
US8524704B2 (en) | 2013-09-03 |
NZ548179A (en) | 2009-11-27 |
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